{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T09:30:41Z","timestamp":1793698241866,"version":"4.5.1"},"reference-count":0,"publisher":"Sultan Qaboos University","issue":"1","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sultan Qaboos University Medical Journal"],"abstract":"<jats:p>Sarcoidosis is an idiopathic multisystem inflammatory disorder characterised by non-caseating granulomas and a wide range of reported prevalence. Renal-limited sarcoidosis is a rare manifestation of sarcoidosis which remains a diagnostic challenge due to lack of extra renal manifestation and specific diagnostic criteria. We report a 37-year-old man who presented to a tertiary care hospital, Muscat, Oman, in 2024, with a two-month history of fever, weight loss, hypercalcaemia, high-to-normal 1,25-Vitamin D, high angiotensin-converting enzyme levels and acute kidney injury. His renal biopsy showed evidence of tubulointerstitial nephritis without granulomas or nephrocalcinosis. After exclusion of infectious, malignant, drug- related and autoimmune causes, a probable diagnosis of renal-limited sarcoidosis was considered. The patient received a course of steroids with subsequent improvement in his symptoms, renal function and renal biopsy inflammatory activity. This case highlights the diagnostic uncertainty and challenges in renal-limited sarcoidosis, particularly in the absence of granulomatous inflammation.<\/jats:p>","DOI":"10.18295\/2075-0528.3004","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T17:58:36Z","timestamp":1787075916000},"page":"466-471","source":"Crossref","is-referenced-by-count":0,"title":["Probable Renal-Limited Sarcoidosis Presenting With Tubulointerstitial Nephritis Without Granulomas on Renal Biopsy: &lt;i&gt;A diagnostic challenge&lt;\/i&gt;"],"prefix":"10.18295","volume":"26","author":[{"given":"Jawahar Hamood","family":"AlNoumani","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Shoaib","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Marzouqi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Sohar Hospital, Sohar, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Al","family":"Lawati","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7681","published-online":{"date-parts":[[2026,8,17]]},"container-title":["Sultan Qaboos University Medical Journal"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T09:17:18Z","timestamp":1793697438000},"score":1,"resource":{"primary":{"URL":"https:\/\/mjournal.squ.edu.om\/home\/vol26\/iss1\/57"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,8,17]]}},"URL":"https:\/\/doi.org\/10.18295\/2075-0528.3004","relation":{},"ISSN":["2075-0528"],"issn-type":[{"value":"2075-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]}}}