{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:45:34Z","timestamp":1774525534692,"version":"3.50.1"},"reference-count":0,"publisher":"Sultan Qaboos University","issue":"2","license":[{"start":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T00:00:00Z","timestamp":1567900800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sultan Qaboos Univ Med J"],"abstract":"<jats:p>ABSTRACT: Objectives: This study aimed to evaluate the aetiologies of hyperprolactinaemia in the United Arab\u00a0Emirates (UAE). Methods: This retrospective study used laboratory databases to identify all patients who underwent\u00a0evaluation for prolactin at Tawam Hospital, Al Ain, UAE, between 2009 and 2015. Of those 2,280 patients, all\u00a0patients with low or normal prolactin (n = 1,315) were excluded. Subsequently, charts of the remaining patients (n= 965) with hyperprolactinaemia were reviewed and those with incomplete work-ups or insufficient documentation\u00a0of the hyperprolactinaemia\u2019s aetiology were excluded (n = 458). Results: A total of 507 patients were included in the study. The average age at prolactin evaluation was 36 \u00b1 13.2 years and the majority (67.1%) of patients were\u00a0female. The most common reasons for requesting prolactin were menstrual disorders (29.5%), infertility (18%),evaluation of sellar masses (14.3%), ruling out seizures (13.4 %) and monitoring while on psychiatric medications\u00a0(8.7%). The most common causes of hyperprolactinaemia were prolactinoma (17%), transient hyperprolactinaemia(14.6%), drug-induced side effects (14.4%), polycystic ovarian syndrome (11.8%) and seizure disorder (7.7%). In\u00a0females, common aetiologies were prolactinomas, transient and idiopathic hyperprolactinaemia, while sellar masses, seizures, chronic kidney disease and acute illnesses were common aetiologies of hyperprolactinaemia in males.\u00a0The prolactin level varied between the different aetiologies and a level of &gt;250 ng\/mL was suggestive of macroprolactinoma.\u00a0Conclusion: A significant proportion of patients with hyperprolactinaemia have transient hyperprolactinaemia.\u00a0Before further investigations are carried out, prolactin level assessment should be repeated, especially\u00a0in patients with mild hyperprolactinaemia.Keywords: Hyperprolactinemia; Prolactinoma; Etiology; Epidemiology; United Arab Emirates.<\/jats:p>","DOI":"10.18295\/squmj.2019.19.02.008","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T06:39:16Z","timestamp":1583908756000},"page":"129","source":"Crossref","is-referenced-by-count":13,"title":["Aetiologies of Hyperprolactinaemia: A retrospective analysis from a tertiary healthcare centre"],"prefix":"10.18295","volume":"19","author":[{"given":"Azhar A.","family":"Malik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salem A.","family":"Beshyah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled M.","family":"Aldahmani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7681","published-online":{"date-parts":[[2019,9,8]]},"container-title":["Sultan Qaboos University Medical Journal [SQUMJ]"],"original-title":[],"link":[{"URL":"https:\/\/journals.squ.edu.om\/index.php\/squmj\/article\/viewFile\/3240\/2683","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.squ.edu.om\/index.php\/squmj\/article\/viewFile\/3240\/2683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T14:55:54Z","timestamp":1744210554000},"score":1,"resource":{"primary":{"URL":"https:\/\/mjournal.squ.edu.om\/home\/vol19\/iss2\/5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,8]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,9,8]]}},"URL":"https:\/\/doi.org\/10.18295\/squmj.2019.19.02.008","relation":{},"ISSN":["2075-0528","2075-051X"],"issn-type":[{"value":"2075-0528","type":"electronic"},{"value":"2075-051X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9,8]]}}}