{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T10:25:35Z","timestamp":1793701535276,"version":"4.5.1"},"reference-count":0,"publisher":"Sultan Qaboos University","issue":"4","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sultan Qaboos University Medical Journal"],"abstract":"<jats:p>Objectives: This study aimed to assess the local epidemiology and outcome of bloodstream infection (BSI) among Omani children. Methods: This retrospective study was conducted at Sultan Qaboos University Hospital, Muscat, Oman, over 5 years (2014\u20132018) and included laboratory-confirmed BSI among children aged 0\u201312 years old. Patients' demographic, clinical and laboratory data were extracted from the hospital's electronic records and used to assess BSI rates and outcomes. Results: A total of 1,253 positive blood cultures were identified, of which 592 (47.2%) were regarded as contaminants. Overall, 404 (32.2%) significant episodes of BSI were identified in 272 patients; 346 (85.6%) significant episodes were in children aged \u00e2\u2030\u00a45 years and 366 (90.6%) had comorbidities. The 5-year incidence of BSI was 13 per 1,000 admissions. Furthermore, 333 (82.4%) episodes were healthcare-related infections. Enterobacterales (n = 152; 37.6%) were the most common organisms identified followed by coagulase-negative staphylococci (n = 63; 15.6%). Approximately 40% of Gram-negative organisms were resistant to third-generation cephalosporins. The crude mortality rate at 30 days was 9.2%. Paediatric intensive care unit admission (crude odds ratio [COR] = 2.24, 95% confidence interval [CI]: 0.98\u20134.78) and the presence of graft-versus-host disease (COR = 7.99, 95% CI: 1.52\u201337.76) were associated with increased death within 30 days. The multivariate logistic regression analysis showed that Pseudomonas aeruginosa (adjusted odds ratio = 18.46, 95% CI: 3.96\u201397.84) was the only independent predictor of increasing 30-day mortality in this cohort. Conclusion: A high rate of hospital-related BSI was found in children in Oman, highlighting the need to optimise infection control strategies and the care of central vein access devices.<\/jats:p>","DOI":"10.18295\/squmj.7.2024.044","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T04:55:12Z","timestamp":1721883312000},"page":"501-506","source":"Crossref","is-referenced-by-count":1,"title":["Bloodstream Infection in Children Managed at a Tertiary Hospital in Oman"],"prefix":"10.18295","volume":"24","author":[{"given":"Nadiya","family":"Al Saeghi","sequence":"first","affiliation":[{"name":"Department of Child Health, Al Nahda Hospital, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwah","family":"Al Thuhli","sequence":"additional","affiliation":[{"name":"Department of Child Health, Al Nahda Hospital, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajer","family":"Al Hamrashi","sequence":"additional","affiliation":[{"name":"Oman Medical Specialty Board, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naema","family":"Al Shibli","sequence":"additional","affiliation":[{"name":"Oman Medical Specialty Board, Muscat, Oman; Department of Child Health, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adil","family":"Al Wahaibi","sequence":"additional","affiliation":[{"name":"Department of Epidemiological Surveillance, Ministry of Health, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Badriya","family":"Al Adawi","sequence":"additional","affiliation":[{"name":"Department of Microbiology & Immunology, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila","family":"Al Yazidi","sequence":"additional","affiliation":[{"name":"Oman Medical Specialty Board, Muscat, Oman; Department of Child Health, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7681","published-online":{"date-parts":[[2024,11,27]]},"container-title":["Sultan Qaboos University Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.squ.edu.om\/index.php\/squmj\/article\/download\/6687\/4147","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.squ.edu.om\/index.php\/squmj\/article\/download\/6687\/4147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T09:26:53Z","timestamp":1793698013000},"score":1,"resource":{"primary":{"URL":"https:\/\/mjournal.squ.edu.om\/home\/vol24\/iss4\/4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,11,27]]}},"URL":"https:\/\/doi.org\/10.18295\/squmj.7.2024.044","relation":{},"ISSN":["2075-0528"],"issn-type":[{"value":"2075-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]}}}