{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:37:02Z","timestamp":1793093822494,"version":"4.5.0"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":["knepublishing.com"],"crossmark-restriction":true},"short-container-title":["AJMB"],"abstract":"<jats:p>Background: Mangrove-associated fungi are widely known due to their bioactivities, especially their antibacterial and lignocellulose-degrading enzymes activity. However, research on their bioactivity in Indonesia, particularly in Jepara Regency remain limited. This research aims to explore the antibacterial and wood-degrading enzymatic pro-perties from mangroves-associated fungi of Jepara, Indonesia.\u00a0\u00a0\nMethods: A total of 43 isolates were successfully collected from leaf and barks of Ex-coecaria agallocha, Acanthus ilicifolius, as well as Lumnitzera racemosa. Antibacterial screening against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was then conducted to all isolates, where 1 isolate was active against E. coli, 12 against S. aureus, and 5 isolates active against both pathogens. All active isolates were identified through microscopic observation.\u00a0\nResults:\u00a0 Isolates with the most consistent inhibition zone, namely AB1, E2D2, E2B4, and LB10 continued to have metabolite extraction and antibacterial assay through disc-diffusion methods against the same 2 pathogens.\u00a0 Isolate E2B4 was able to produce the largest halo zone diameter measuring 22.28\u00b11.59 mm at concentration of 50 mg\/mL against S. aureus. Based on preliminary phytochemical screening, crude extract of E2B4 contains flavonoid and alkaloid as secondary metabolite. To search for further bioactivity, wood-degrading enzymatic assay was conducted, where the result showed that 6 isolates were actively produced cellulase, 1 laccase, 7 tannase, and 5 lignin peroxidase. DNA barcoding revealed that AB1, E2D2, and E2B4 isolates were identified as Phaeophleospora eucalypticola, Curvularia lunata, and Paraconiothyrium sp., respectively.\u00a0\u00a0\nConclusion: Therefore, these findings highlight mangrove-associated fungi bio-activities potential through screening assay and provide critical information regarding the rarely studied Indonesian fungi.\u00a0\n\u00a0<\/jats:p>","DOI":"10.18502\/ajmb.v18i3.22242","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T13:00:58Z","timestamp":1785934858000},"update-policy":"https:\/\/doi.org\/10.18502\/knecrossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Bioactivities of Mangrove-Associated Filamentous Fungi from Jepara, Indonesia:    Anti-Bacterial Metabolites and Wood-Degrading Enzymes"],"prefix":"10.18502","author":[{"given":"Christian","family":"Wibowo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delianis","family":"Pringgenies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sri","family":"Sedjati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7770","published-online":{"date-parts":[[2026,8,5]]},"container-title":["Avicenna Journal of Medical Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/AJMB\/article\/download\/22242\/20725","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/AJMB\/article\/download\/22242\/20725","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:15:03Z","timestamp":1793092503000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/AJMB\/article\/view\/22242"},"secondary":[{"URL":"https:\/\/submission.ajmb.org\/article_250474.html","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ajmb.v18i3.22242","relation":{},"ISSN":["2008-4625","2008-2835"],"issn-type":[{"value":"2008-4625","type":"electronic"},{"value":"2008-2835","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,5]]}}}