{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T10:27:29Z","timestamp":1772015249635,"version":"3.50.1"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["fid"],"abstract":"<jats:p>Objectives: This study compared the antimicrobial effects of Endoseal MTA and AH Plus sealers on Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) mature biofilms on dentin blocks.\r\nMaterials and Methods: In this in vitro study, the root canals of 207 dentin blocks sectioned from the roots of extracted teeth were inoculated with E. faecalis and C. albicans, and incubated for 3 weeks. The specimens were evaluated in 12 groups (n=17) for random root canal filling with AH Plus, Endoseal MTA, or no sealer, and assessment after 24 hours and 2 weeks. Dentin chips were cultured on blood agar, and the colonies were counted. One random specimen from each group was assessed under a scanning electron microscope (SEM). Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests with Bonferroni adjustment at 0.05 level of significance.\r\nResults: At 24 hours, Endoseal MTA significantly decreased the E. faecalis count compared with the positive control (P&lt;0.008). At 2 weeks, the colony count of both microorganisms was significantly lower in the AH Plus group compared with the control group (P&lt;0.008). The C. albicans colony count in the Endoseal MTA group was significantly lower than that in the control group at 2 weeks (P&lt;0.008). AH Plus caused significantly greater reduction in C. albicans colony count at 2 weeks compared with Endoseal MTA (P&lt;0.008).\r\nConclusion: AH Plus showed a higher antimicrobial activity over time against both E. faecalis and C. albicans. Endoseal MTA only showed short-term antibacterial effect.<\/jats:p>","DOI":"10.18502\/fid.v22i19.18760","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T04:33:29Z","timestamp":1748320409000},"source":"Crossref","is-referenced-by-count":0,"title":["In Vitro Antimicrobial Effects of Endoseal MTA and AH Plus Sealers on Enterococcus Faecalis and Candida Albicans Mature Biofilms"],"prefix":"10.18502","author":[{"given":"Elham","family":"Khoshbin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Forough","family":"Nikzad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Reza","family":"Arabestani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Farhdian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamed","family":"Karkehabadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2025,5,27]]},"container-title":["Frontiers in Dentistry"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/fid\/article\/download\/18760\/17852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/fid\/article\/download\/18760\/17852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:46:12Z","timestamp":1772012772000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/fid\/article\/view\/18760"},"secondary":[{"URL":"https:\/\/fid.tums.ac.ir\/index.php\/fid\/article\/view\/4610","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/fid.v22i19.18760","relation":{},"ISSN":["2676-296X"],"issn-type":[{"value":"2676-296X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,27]]}}}