{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T05:35:33Z","timestamp":1734500133403,"version":"3.30.2"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJM"],"abstract":"<jats:p>Background and Objectives: This study aimed to detect SARS-CoV-2 in conjunctival samples of COVID-19 patients to investigate the transmission route of COVID-19 and its correlation with laboratory indexes.\r\nMaterials and Methods: In this cross-sectional study, 44 COVID-19 patients were tested for conjunctival PCR in Ayatollah Rouhani hospital of Babol, Iran, in January and February 2021. The conjunctival samples were collected using a conjunctival swab and suspended in a viral transport medium. After RNA extraction and cDNA synthesis, real-time PCR was performed to investigate the SARS-CoV-2 genome in samples. The ocular manifestations and laboratory indexes were evaluated for all patients.\r\nResults: Among 44 COVID-19 patients, 6 samples (13.63%) were positive in terms of conjunctival PCR. The mean \u00b1 SD age of conjunctival PCR-positive patients was 76.17 \u00b1 16.61-year-old, while conjunctival PCR-negative COVID-19 pa- tients were aged 57.54 \u00b1 13.61-year-old (p &lt;0.05). D-dimer serum level is significantly higher in conjunctival PCR-positive COVID-19 patients (4001.00 \u00b1 3043.36 \u00b5g\/ml) compared to normal individuals (496.80 \u00b1 805.92 \u00b5g\/ml, p &lt;0.01).\r\nConclusion: Our study showed that the conjunctiva and tear contain the SARS-CoV-2 in COVID-19 patients as a possible transmission route.<\/jats:p>","DOI":"10.18502\/ijm.v13i6.8074","type":"journal-article","created":{"date-parts":[[2021,12,25]],"date-time":"2021-12-25T06:41:25Z","timestamp":1640414485000},"source":"Crossref","is-referenced-by-count":0,"title":["Conjunctival polymerase chain reactions in COVID-19 patients and its correlation with clinical and paraclinical indexes"],"prefix":"10.18502","author":[{"given":"Maral","family":"Farzin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Ahmad","family":"Rasoulinejad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansour","family":"Babaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzin","family":"Sadeghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Sadeghi-Haddad-Zavareh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Firouzjahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behzad","family":"Heidari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2021,12,22]]},"container-title":["Iranian Journal of Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/8074\/7752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/8074\/7752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T16:45:42Z","timestamp":1734453942000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/8074"},"secondary":[{"URL":"https:\/\/ijm.tums.ac.ir\/index.php\/ijm\/article\/view\/3179","label":"UNIVERSITY"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/8074","label":"PUBLISHER"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,22]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijm.v13i6.8074","relation":{},"ISSN":["2008-4447","2008-3289"],"issn-type":[{"type":"electronic","value":"2008-4447"},{"type":"print","value":"2008-3289"}],"subject":[],"published":{"date-parts":[[2021,12,22]]}}}