{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T03:38:49Z","timestamp":1774496329124,"version":"3.50.1"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJM"],"abstract":"<jats:p>Background and Objectives: Candida albicans complex species are well known as the main cause of candidiasis, particu- larly among susceptible individuals. In this study, we report the genetic diversity of Candida spp. and the antifungal suscep- tibility pattern of the cryptic C. albicans complex isolates in Kerman, Iran.\r\nMaterials and Methods: A total of 112 yeast isolates were obtained from different clinical samples, and molecular identifi- cation was performed. All C. albicans complex isolates were tested for susceptibility of them to amphotericin B, fluconazole, and itraconazole.\r\nResults: The majority of clinical isolates were C. albicans complex (n=48) followed by C. glabrata complex (n=34), C. parapsilosis complex (n=21), and C. krusei (n=9). Among C. albicans complex, 45 isolates were C. albicans (94%), 2 iso- lates were C. dubliniensis (4%), and 1 isolate was C. africana (2%). Amphotericin B was the most active antifungal, whereas. 8.9% and 6.7% of the isolates were resistant to fluconazole and itraconazole, respectively.\r\nConclusion: Regarding the high incidence of Candida infections particularly in susceptible populations and the emergence of an infrequent yeast species with elevated MICs, which is indistinguishable with conventional methods, developing accu- rate molecular methods for laboratory diagnosis should be considered in the clinical setting.<\/jats:p>","DOI":"10.18502\/ijm.v14i3.9795","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T11:36:31Z","timestamp":1655811391000},"source":"Crossref","is-referenced-by-count":2,"title":["Molecular discrimination and antifungal susceptibility profile of cryptic Candida albicans complex species isolated from patients in Iran"],"prefix":"10.18502","author":[{"given":"Ashkan","family":"Faridi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azam","family":"Amanizadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyyed Amin","family":"Ayatollahi Mosavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Salari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davood","family":"Kalantar-Neyestanaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somayeh","family":"Sharifynia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Setareh","family":"Agha Kuchak Afshari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2022,6,20]]},"container-title":["Iranian Journal of Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/9795\/9339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/9795\/9339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T17:01:39Z","timestamp":1734454899000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/9795"},"secondary":[{"URL":"https:\/\/ijm.tums.ac.ir\/index.php\/ijm\/article\/view\/3280","label":"UNIVERSITY"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/9795","label":"PUBLISHER"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,20]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijm.v14i3.9795","relation":{},"ISSN":["2008-4447","2008-3289"],"issn-type":[{"value":"2008-4447","type":"electronic"},{"value":"2008-3289","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,20]]}}}