{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:03:55Z","timestamp":1772107435274,"version":"3.50.1"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJM"],"abstract":"<jats:p>Background and Objectives: Dermatophytosis is a significant worldwide health concern, particularly in tropical and sub- tropical regions. Tinea unguium (TU) and Tinea capitis (TC) are among the most prevalent clinical manifestations of der- matophytosis caused by several dermatophyte fungi. This study investigated the molecular epidemiology and distribution of dermatophytes causing TU and TC in Tehran, Iran.\r\nMaterials and Methods: From March 2023 to March 2024, a clinical mycology center in Tehran received 342 suspected cases of TU and TC. The diagnostic methods included the conventional and molecular methods by sequencing the ITS region of ribosomal DNA.\r\nResults: Overall prevalence of dermatophytosis was 59\/342 (17.2%) among suspected patients by direct examination. TU and TC were diagnosed in 31\/59 (53%) and 28\/59 (47%), respectively. The final prevalence among suspected patients was 43\/342 (12.5%) by PCR-sequencing, and TC accounted for the largest group of them, 25\/43 (58%). Females repre- sented the largest group of suspected TU cases (204\/303, 67%; mean age: 57 years), while males predominated among TC patients (28\/39, 74%; mean age: 10 years). PCR-sequencing revealed Trichophyton tonsurans was the most common agent of TC, 22\/25 (88%), and Trichophyton indotineae emerged as a notable cause of TU in 5\/18 (28%) of confirmed cases.\r\nConclusion: In our study, T. tonsurans remained the predominant cause of TC, while T. indotineae emerged as a signifi- cant cause of TU. Agreement between conventional and molecular methods was substantial (\u03ba=0.73, 95% CI: 0.61\u20130.85), with 81.8% misidentification of the T. mentagrophytes complex but complete accuracy for T. tonsurans and Microsporum canis.<\/jats:p>","DOI":"10.18502\/ijm.v17i5.19895","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:58:51Z","timestamp":1760428731000},"source":"Crossref","is-referenced-by-count":0,"title":["Shifting etiological agents of dermatophytosis: a molecular epidemiological study from Iran"],"prefix":"10.18502","author":[{"given":"Mahsa Naeimi","family":"Eshkaleti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Jamal","family":"Hashemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadegh","family":"Khodavaisy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roshanak Daie","family":"Ghazvini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazem","family":"Ahmadikia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas Rahimi","family":"Foroshani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Ahmadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasibeh","family":"Ghasemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2025,10,13]]},"container-title":["Iranian Journal of Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/19895\/18587","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/19895\/18587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T11:16:01Z","timestamp":1772104561000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/19895"},"secondary":[{"URL":"https:\/\/ijm.tums.ac.ir\/index.php\/ijm\/article\/view\/5494","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,13]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijm.v17i5.19895","relation":{},"ISSN":["2008-4447","2008-3289"],"issn-type":[{"value":"2008-4447","type":"electronic"},{"value":"2008-3289","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,13]]}}}