{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T15:09:38Z","timestamp":1772204978780,"version":"3.50.1"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJM"],"abstract":"<jats:p>Background and Objectives: Candiduria related to urinary catheters is frequently encountered in patients hospitalized in intensive care units. The diagnosis and management of catheter-associated candiduria in hospitalized patients is frequently a gray area for both physicians and microbiologists because of the paucity of clinical and microbiological data.\r\nMaterials \u00a0and \u00a0Methods:\u00a0 This \u00a0cross-sectional \u00a0study aims \u00a0to \u00a0enhance \u00a0the \u00a0understanding of \u00a0candiduria \u00a0among \u00a0adult ICU \u00a0patients \u00a0with \u00a0urinary \u00a0catheters \u00a0across \u00a0three \u00a0hospitals \u00a0in \u00a0Tehran, \u00a0Iran. \u00a0Yeast \u00a0identification\u00a0 was \u00a0performed \u00a0us- ing a two-step multiplex PCR, and antifungal susceptibility testing was performed following the CLSI M27, 4th \u00a0edition, recommendations.\r\nResults: Among the 110 enrolled ICU patients, 38 (35%) had significant candiduria. A total of 45 yeast isolates were col- lected. The distribution was as follows: Candida glabrata (23\/45; 51%), C. albicans (14\/45; 31%), and C. tropicalis (4\/45; 9%). These three species accounted for 91% of the isolates. Antifungal resistance was detected: six isolates (two C. glabrata, two C. albicans, one C. krusei, and one C. tropicalis) were fluconazole-resistant, and one C. glabrata isolate was resistant to itraconazole, voriconazole, and caspofungin. All isolated species were susceptible to amphotericin B. Symptomatic can- diduria occurred in 29% of cases (11\/38); only 55% (6\/11) were treated, and of those, 50% (3\/6) experienced fluconazole treatment failure. One symptomatic patient developed candidemia shortly after acquiring candiduria. The mortality rate was 21% (8\/38), with no apparent difference in death rates between symptomatic and asymptomatic candiduric patients.\r\nConclusion: Our findings reveal that high fluconazole failure rates among patients with symptomatic candiduria are concern- ing. Furthermore, speciation and antifungal susceptibility testing are crucial, as they guide clinicians in selecting the most effective agent and improving case management.<\/jats:p>","DOI":"10.18502\/ijm.v18i1.20939","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:43:35Z","timestamp":1771062215000},"source":"Crossref","is-referenced-by-count":0,"title":["Candiduria in catheterized ICU patients: epidemiology, molecular identification, and antifungal susceptibility"],"prefix":"10.18502","author":[{"given":"Ali","family":"Ahmadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebrahim","family":"Hazrati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahtab","family":"Noorifard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohreh","family":"Farahnejad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojgan","family":"Mohammadimehr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2026,2,12]]},"container-title":["Iranian Journal of Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/20939\/19593","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/download\/20939\/19593","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T14:16:56Z","timestamp":1772201816000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJM\/article\/view\/20939"},"secondary":[{"URL":"https:\/\/ijm.tums.ac.ir\/index.php\/ijm\/article\/view\/5045","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,12]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijm.v18i1.20939","relation":{},"ISSN":["2008-4447","2008-3289"],"issn-type":[{"value":"2008-4447","type":"electronic"},{"value":"2008-3289","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,12]]}}}