{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T21:27:41Z","timestamp":1769635661851,"version":"3.49.0"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJPA"],"abstract":"<jats:p>Background: The possible risk factor of Toxoplasma infection and its possible correlation with Interleukin-12 (IL-12) and Interleukin-23 (IL-23) in breast cancer patients was investigated.\r\nMethods: Overall, 190 female patients referred to the Oncology Teaching Hospital in the Medical City Hospital, Baghdad, Iraq were enrolled from 2017-2018. All serum samples were tested for T. gondii immunoglobulins (IgG and IgM (antibodies and IL-12, IL-23 levels.\r\nResults: In patients with breast cancer, the results revealed a high positivity percentage for anti- Toxoplasma IgG. In breast cancer patients infected with T. gondii, the IL-12 level was lower than the controls while the mean level of IL-23 was higher than the controls. According to the cancer grade in breast cancer patients infected with T. gondii, the higher mean titer of IgG and IL-23 was in grade 3 in contrast the highest mean titer of IL-12 was in grade 1. Concerning the tumor stages in breast cancer patients infected with T. gondii, the higher mean titer of IgG, IL-12 and IL-23 was in stage (III). According to the tumor size in breast cancer patients infected with T. gondii, the highest mean titer of IgG, IL-12 and IL-23 was in size &gt;3cm.\r\nConclusion: The levels of IL-23 could be a candidate as a non-invasive primitive marker for earlier prediction of breast cancer stage.<\/jats:p>","DOI":"10.18502\/ijpa.v15i4.4850","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T11:50:48Z","timestamp":1608033048000},"source":"Crossref","is-referenced-by-count":3,"title":["Serum Levels of Il-12 and Il-23 in Breast Cancer Patients Infected with Toxoplasma gondii: A Case-Control Study"],"prefix":"10.18502","author":[{"given":"Maha Mustafa","family":"ASSIM","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Entsar Jabbar","family":"SAHEB","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2020,12,14]]},"container-title":["Iranian Journal of Parasitology"],"original-title":[],"link":[{"URL":"https:\/\/18.184.16.47\/index.php\/IJPA\/article\/download\/4850\/4155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/18.184.16.47\/index.php\/IJPA\/article\/download\/4850\/4155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T16:15:50Z","timestamp":1734452150000},"score":1,"resource":{"primary":{"URL":"https:\/\/18.184.16.47\/index.php\/IJPA\/article\/view\/4850"},"secondary":[{"URL":"https:\/\/ijpa.tums.ac.ir\/index.php\/ijpa\/article\/view\/3166","label":"UNIVERSITY"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJPA\/article\/view\/4850","label":"PUBLISHER"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,14]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijpa.v15i4.4850","relation":{},"ISSN":["1735-7020"],"issn-type":[{"value":"1735-7020","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,14]]}}}