{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:26:35Z","timestamp":1787023595596,"version":"build-2736575974"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJPA"],"abstract":"<jats:p>Background: We aimed to conduct a comprehensive analysis of cutaneous leishmaniasis\u2019s (CL) clinical polymorphism by examining the relationship between clinical forms, duration of illness, and their spatiotemporal distribution.\r\nMethods: A retrospective study at University of Gondar Hospital analyzed cutaneous leishmaniasis patients treated from 2022 to 2024. Demographic and epidemiologic data were collected, with parasite detection via microscopic and clinical examination.\r\nResults: Overall, 454 CL cases from 49 districts were diagnosed, predominantly affecting males aged \u226430, with a mean age of 25.31 yr (SD \u00b118.3). Significant differences were noted in age and sex (P&lt;0.05). Approximately 70% had lesions \u22654 cm. Most CL cases had 2+ parasite loads. Sodium stibogluconate (SSG) remained the primary treatment choice for patients. The spatial distribution of CL cases covered a larger geographical area, although the cases (&gt;20) were concentrated in Central Gondar. The mucosal CL shared a similar geographical pattern with the recurrent CL type. Notably, 48% had chronic presentations and lived with the disease for \u226512 months. In diffuse CL (DCL) a longer delay was seen and its clinical presentation was associated with longitudinal time series. Acute patients exhibited a higher parasitic load than chronic ones (38% vs. 24%), respectively.\r\nConclusion: CL significantly affected school-aged children. The symmetrical distribution of cases in districts studied could increase the attention of clinicians and enhance management strategies. Extended disease durations necessitated specialized treatments for clinical transitions.<\/jats:p>","DOI":"10.18502\/ijpa.v20i2.19026","type":"journal-article","created":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T16:06:51Z","timestamp":1751818011000},"source":"Crossref","is-referenced-by-count":1,"title":["Spatial Epidemiology of Clinical Forms of Cutaneous Leishmaniasis and Treatment Practice: Evidence from Leishmaniasis Research and Treatment Center, Northwest Ethiopia"],"prefix":"10.18502","author":[{"given":"Bizuayehu","family":"Gashaw","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endalew","family":"Yizengaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endalkachew","family":"Nibret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7770","published-online":{"date-parts":[[2025,7,2]]},"container-title":["Iranian Journal of Parasitology"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJPA\/article\/download\/19026\/17752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJPA\/article\/download\/19026\/17752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T10:26:11Z","timestamp":1772015171000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/IJPA\/article\/view\/19026"},"secondary":[{"URL":"https:\/\/ijpa.tums.ac.ir\/index.php\/ijpa\/article\/view\/4469","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,2]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijpa.v20i2.19026","relation":{},"ISSN":["1735-7020"],"issn-type":[{"value":"1735-7020","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7,2]]}}}