{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T05:16:53Z","timestamp":1737695813992,"version":"3.33.0"},"reference-count":14,"publisher":"Knowledge E DMCC","issue":"1","content-domain":{"domain":["knepublishing.com"],"crossmark-restriction":true},"short-container-title":["IJRM"],"abstract":"<jats:p>Background: Preterm labor (PTL) is one of the most important factors in neonatal mortality. Some studies have revealed a reverse relationship between cervical length (CL) and PTL, however, further evidence is needed to confirm it.\r\nObjective: To investigate the predictive value of CL in spontaneous and in vitro fertilization (IVF) pregnancies.\r\nMaterials and Methods: This prospective cohort study was performed on 154 pregnant women from 16-26 wk of gestation with a singleton fetus in spontaneous delivery (n = 77) and IVF pregnancies (n = 77) and followed up until delivery. Women with multiple pregnancy, placenta previa, cerclage, and congenital anomalies were excluded from the study. The cut-off determination was done according to the Roc analysis.\r\nResults: The mean CL in term delivery and PTL groups were 37 \u00b1 7 mm and 31 \u00b1 6 mm, respectively (p &lt; 0.001). The frequency of PTL in spontaneous and IVF pregnancies were 7.8% and 23.27%, respectively (p = 0.007). According to the Roc analysis, the best cut-off for normal pregnancy was \u2264 36 mm with the negative predictive value of 97.9%, the positive predictive value of 11.4%, sensitivity 83.3%, and specificity of 46.5%. While for the IVF group, the cut off was \u2264 30 mm, with a negative predictive value of 88.4%, a positive predictive value of 57.8%, sensitivity of 63.2%, and a specificity of 86%.\r\nConclusion: In this study, IVF had a significant direct correlation with PTL. CL also had a significant indirect relationship with PTL.\r\nKey words: Cervix, IVF, Preterm delivery, PTL.<\/jats:p>","DOI":"10.18502\/ijrm.v19i1.8180","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T05:34:50Z","timestamp":1611639290000},"page":"57-62","update-policy":"https:\/\/doi.org\/10.18502\/knecrossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: A cohort study"],"prefix":"10.18502","volume":"19","author":[{"given":"Razieh","family":"Mohammad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahvash","family":"Zargar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojgan","family":"Barati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somayeh","family":"Ershadian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"Berghella V, Palacio M, Ness A, Alfirevic Z, Nicolaides KH, Saccone G. Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data. Ultrasound Obstet Gynecol 2017; 49: 322\u2013329.","key":"110292","DOI":"10.1002\/uog.17388"},{"doi-asserted-by":"crossref","unstructured":"Sharvit M, Weiss R, Ganor Paz Y, Tzadikevitch Geffen K, Danielli Miller N, Biron-Shental T. Vaginal examination vs. cervical length - which is superior in predicting preterm birth?. J Perinat Med 2017; 45: 977\u2013983.","key":"110293","DOI":"10.1515\/jpm-2016-0273"},{"doi-asserted-by":"crossref","unstructured":"Leitich H, Brunbauer M, Kaider A, Egarter Ch, Husslein P. Cervical length and dilatation of the internal cervical os detected by vaginal ultrasonography as markers for preterm delivery: A systematic review. 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Int J Environ Res Public Health 2013; 10: 2296\u20132335.","key":"110297","DOI":"10.3390\/ijerph10062296"},{"doi-asserted-by":"crossref","unstructured":"Cavoretto P, Candiani M, Giorgione V, Inversetti A, Abu- Saba MM, Tiberio F, et al. Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF\/ICSI treatment: meta-analysis of cohort studies. Ultrasound Obstet Gynecol 2018; 51: 43\u201353.","key":"110298","DOI":"10.1002\/uog.18930"},{"unstructured":"Mohamadjafari R, Nagafian M, Vahaby E, Gharibzadeh S. [Correlation between cervical length by transvaginal sonography at 16-24wks of pregnancy and preterm labor.] Stud Med Sci 2013; 24: 441\u2013448. (in Persian)","key":"110299"},{"doi-asserted-by":"crossref","unstructured":"Pasquini L, Sisti G, Nasioudis D, Kanninen T, Sorbi F, Fambrini M, et al. Ability of cervical length to predict spontaneous preterm delivery in twin pregnancies using the receiver-operating characteristic curve analysis and an a priori cut-off value. J Obstet Gynaecol 2017; 37: 562\u2013565.","key":"110300","DOI":"10.1080\/01443615.2016.1258046"},{"unstructured":"Szymusik I, Wegrzyn P, Marianowski P, Dziadecki W, Bablok L, Wielgos M. Is mid-gestational cervical length measurement as sensitive prediction factor of preterm delivery in IVF as in spontaneous singleton pregnancies? Neuro Endocrinol Lett 2011; 32: 453\u2013457.","key":"110301"},{"doi-asserted-by":"crossref","unstructured":"Al-Safi ZA, Shavell VI, Roberts RP, Singh M, Puscheck EE, Diamond MP. First trimester cervical length and preterm delivery in pregnancies conceived through in vitro fertilization. Fertil Steril 2011; 96: S13.","key":"110302","DOI":"10.1016\/j.fertnstert.2011.07.057"},{"doi-asserted-by":"crossref","unstructured":"Berghella V, Baxter JK, Hendrix NW. Cervical assessment by ultrasound for preventing preterm delivery. Cochrane Database Syst Rev 2009; 2: CD007235.","key":"110303","DOI":"10.1002\/14651858.CD007235.pub2"},{"doi-asserted-by":"crossref","unstructured":"O\u2019Hara S, Zelesco M, Sun Z. Cervical length for predicting preterm birth and a comparison of ultrasonic measurement techniques. Aust J Ultrasound Med 2013; 16: 124\u2013134.","key":"110304","DOI":"10.1002\/j.2205-0140.2013.tb00100.x"},{"doi-asserted-by":"crossref","unstructured":"Iams JD, Goldenberg RL, Meis PJ, Mercer BM, Moawad A, Das A, et al. The length of the cervix and the risk of spontaneous premature delivery. 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