{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T05:34:04Z","timestamp":1734500044325,"version":"3.30.2"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JFRH"],"abstract":"<jats:p>Objective: The purpose of this study was comparison of association of three main first trimester screening factors with pregnancy outcomes among Iranian pregnant women.\r\nMaterials and methods: This prospective study was done during 2017-2019 years in Qazvin, Iran. To do so, a total of 1500pregnant women in first trimester were enrolled. At the first step, Nuchal translucency (NT) was measured in 11-13 \u00b1 5 week, then the serum pregnancy-associated plasma protein A (PAPP-A) and free-\u03b2-human chorionic gonadotropin (free-\u03b2-HCG) were measured in 12-14 weeks of gestation. Pregnant women were followed up until the end of pregnancy for the complications of pregnancy such as intra-uterine growth retardation (IUGR), intrauterine death (IUFD), different types of fetal loss and preterm labor.\r\nResults: The results showed that low levels of serum biomarkers had more association with pregnancy complications in comparison to high levels of them. Significant association of IUGR (P = 0.001), IUFD (P = 0.032) and pre-term labor (P = 0.002) was shown in women with low serum levels of PAPP-A in comparison to low serum levels of free-\u03b2-hCG. Significant high frequency of different types of fetal loss (IUFD, Abortion, Elective termination) was shown in fetuses with N \u2265 3 in comparison to low levels of serum biomarkers (P = 0.001).\r\nConclusion: This study highlighted the importance of accurately interpreting the results of the first trimester of pregnancy screening which should be considered by primatologists for subsequent pregnancy care.<\/jats:p>","DOI":"10.18502\/jfrh.v14i2.4349","type":"journal-article","created":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T12:16:03Z","timestamp":1602072963000},"source":"Crossref","is-referenced-by-count":0,"title":["High Frequency of Fetal Loss in Fetuses with Normal  Karyotype and Nuchal Translucency \u2265 3 among the  Iranian Pregnant Women"],"prefix":"10.18502","author":[{"given":"Shokoh","family":"Abotorabi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niloufar","family":"Moeini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar","family":"Moghbelinejad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2020,10,7]]},"container-title":["Journal of Family &amp; Reproductive Health"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JFRH\/article\/download\/4349\/4243","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JFRH\/article\/download\/4349\/4243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T16:11:23Z","timestamp":1734451883000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JFRH\/article\/view\/4349"},"secondary":[{"URL":"https:\/\/jfrh.tums.ac.ir\/index.php\/jfrh\/article\/view\/1254","label":"UNIVERSITY"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JFRH\/article\/view\/4349","label":"PUBLISHER"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/jfrh.v14i2.4349","relation":{},"ISSN":["1735-9392","1735-8949"],"issn-type":[{"type":"electronic","value":"1735-9392"},{"type":"print","value":"1735-8949"}],"subject":[],"published":{"date-parts":[[2020,10,7]]}}}