{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:22:31Z","timestamp":1757701351743,"version":"3.40.4"},"reference-count":13,"publisher":"Knowledge E DMCC","issue":"3","content-domain":{"domain":["knepublishing.com"],"crossmark-restriction":true},"short-container-title":["JOVR"],"abstract":"<jats:p>Purpose: To report a case of advanced childhood glaucoma secondary to congenital ectropion uveae (CEU).\r\nCase Report: The patient was a seven-year-old boy with unilateral glaucoma secondary to CEU and facial asymmetry, mild unilateral ptosis, and proptosis in the left eye. The intraocular pressure (IOP) was 28 mmHg and cup-to-disc ratio was 0.8 in the left eye. After starting glaucoma medication, IOP decreased to 21 mmHg. In view of the uncontrolled IOP with medication and high cup-to-disc ratio and increased axial length of the left eye, mitomycin-C (MMC)-augmented trabeculectomy was planned. Despite sub-tenon MMC injection and bleb needling, the bleb failed after six months, and we had to perform a shunt procedure to control the IOP.\r\nConclusion: Although CEU is rare, ophthalmologists should be familiar with this syndrome because of the high frequency of glaucoma and its challenging management during childhood.<\/jats:p>","DOI":"10.18502\/jovr.v14i3.4793","type":"journal-article","created":{"date-parts":[[2019,7,20]],"date-time":"2019-07-20T05:11:30Z","timestamp":1563599490000},"page":"370-375","update-policy":"https:\/\/doi.org\/10.18502\/knecrossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Glaucoma in Ectropion Uveae Syndrome: a Case Report and Literature Review"],"prefix":"10.18502","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2733-7802","authenticated-orcid":false,"given":"Mohammadmehdi","family":"Hatami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azadeh","family":"Doozandeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohadeseh","family":"Feizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2019,7,18]]},"reference":[{"key":"15373","doi-asserted-by":"crossref","unstructured":"Ritch R, Forbes M, Hetherington J, Jr, Harrison R, Podos SM. Congenital ectropion uveae with glaucoma. Ophthalmology 1984;91:326\u2013331.","DOI":"10.1016\/S0161-6420(84)34288-9"},{"key":"15374","doi-asserted-by":"crossref","unstructured":"Morales J, Chaudhry IA, Bosley TM. Glaucoma and globe enlargement associated with neurofibromatosis type 1. Ophthalmology 2009;116:1725\u20131730.","DOI":"10.1016\/j.ophtha.2009.06.019"},{"key":"15375","unstructured":"Edward DP, Morales J, Bouhenni RA, Patil J, Edward PR, Cummings TJ, et al. Congenital ectropion uvea and"},{"key":"15376","doi-asserted-by":"crossref","unstructured":"mechanisms of glaucoma in neurofibromatosis type 1: new insights. Ophthalmology 2012;119:1485\u20131194.","DOI":"10.1016\/j.ophtha.2012.01.027"},{"key":"15377","unstructured":"Skuta GL, Cantor LB, Cioffi GA. Childhood glaucoma. In: Glaucoma 2013-2014. Section 10. San Francisco, CA:"},{"key":"15378","unstructured":"American Academy of ophthalmology (AAO); 2004: 148."},{"key":"15379","doi-asserted-by":"crossref","unstructured":"Dowling JL, Jr, Albert DM, Nelson LB, Walton DS. Primary glaucoma associated with iridotrabecular dysgenesis and ectropion uveae. Ophthalmology 1985;92:912\u2013921.","DOI":"10.1016\/S0161-6420(85)33935-0"},{"key":"15380","doi-asserted-by":"crossref","unstructured":"Wilson ME. Congenital iris ectropion and a new classification for anterior segment dysgenesis. J Pediatr Ophthalmol Strabismus 1990;27:48\u201355.","DOI":"10.3928\/0191-3913-19900101-13"},{"key":"15381","doi-asserted-by":"crossref","unstructured":"Bansal A, Luck J. Primary iris pigment epithelial hyperplasia and glaucoma. Brit J Ophthalmol 2002;86:352\u2013353.","DOI":"10.1136\/bjo.86.3.352"},{"key":"15382","doi-asserted-by":"crossref","unstructured":"Beck AD. Diagnosis and management of pediatric glaucoma. Ophthalmol Clin North Am 2001;14:501\u2013512.","DOI":"10.1016\/S0896-1549(05)70248-0"},{"key":"15383","unstructured":"Salim S, Shields MB. Iridocorneal Endothelial Syndrome and Glaucoma. EyeNet Magazine 2011;15:47\u201349."},{"key":"15384","unstructured":"Salim S, Walton DS. Goniotomy and trabeculotomy. In: Yanoff M, Duker JS. Ophthalmology. 3rd ed. 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