{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T01:03:00Z","timestamp":1759798980429,"version":"build-2065373602"},"reference-count":9,"publisher":"Knowledge E DMCC","issue":"2","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["knepublishing.com"],"crossmark-restriction":true},"short-container-title":["JOVR"],"abstract":"<jats:p>Purpose: To report a case of adult-onset asthma and periocular xanthogranuloma (AAPOX) in a patient with intermediate uveitis and a history of Hodgkin\u2019s lymphoma (HL).\r\nCase Report: A 51-year-old man with a past medical history of HL presented with blurred vision, asthma, and bilateral yellowish eyelid lesions. The eyelid lesions and asthma appeared 10 years after being diagnosed with HL. Physical examination was significant for multiple subcutaneous and firm eyelid masses in addition to the presence of pre-auricular and submandibular lymphadenopathies. Ophthalmic examination revealed bilateral intermediate uveitis and mild macular edema. Further systemic evaluations, including laboratory testing and imaging, were normal. Excisional biopsy of the eyelid lesions was performed and the histopathologic examination was consistent with the diagnosis of AAPOX.\r\nConclusion: The presence of AAPOX in a patient with intermediate uveitis and history of HL suggests that immunological dysfunction may play a role in the pathogenesis of adult orbital xanthogranulomatous disease.<\/jats:p>","DOI":"10.18502\/jovr.v19i2.9629","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T03:29:05Z","timestamp":1720409345000},"page":"255-259","update-policy":"https:\/\/doi.org\/10.18502\/knecrossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Presentation of Adult-onset Asthma and Periocular Xanthogranuloma with Intermediate Uveitis and Hodgkin\u2019s Lymphoma: A Case Report"],"prefix":"10.18502","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7388-6725","authenticated-orcid":false,"given":"Sahba","family":"Fekri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad-Hasan","family":"Rikhtehgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6736-7435","authenticated-orcid":false,"given":"Abbas","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8304-3804","authenticated-orcid":false,"given":"Amirreza","family":"Veisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir A.","family":"Azari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"190504","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.03.010"},{"key":"190505","unstructured":"Jakobiec FA, Mills MD, Hidayat AA, Dallow RL, Townsend DJ, Brinker EA, et al. Periocular xanthogranulomas associated with severe adult-onset asthma. Trans Am Ophthalmol Soc 1993;91:99\u2013125."},{"key":"190506","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.085894"},{"key":"190507","doi-asserted-by":"publisher","DOI":"10.5858\/133.12.1994"},{"key":"190508","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000191"},{"key":"190509","doi-asserted-by":"publisher","DOI":"10.1097\/01.IOP.0000132177.20945.E9"},{"key":"190510","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001916"},{"key":"190511","doi-asserted-by":"publisher","DOI":"10.20452\/pamw.14933"},{"key":"190512","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpa.0000236737.84982.45"}],"container-title":["Journal of Ophthalmic and Vision Research"],"original-title":[],"link":[{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/9629\/26149","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/9629\/26289","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/9629\/26149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T19:11:10Z","timestamp":1759777870000},"score":1,"resource":{"primary":{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/view\/9629"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,21]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,6,21]]}},"URL":"https:\/\/doi.org\/10.18502\/jovr.v19i2.9629","relation":{},"ISSN":["2008-322X","2008-2010"],"issn-type":[{"type":"electronic","value":"2008-322X"},{"type":"print","value":"2008-2010"}],"subject":[],"published":{"date-parts":[[2024,6,21]]}}}