{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T10:17:22Z","timestamp":1771496242479,"version":"3.50.1"},"reference-count":38,"publisher":"Knowledge E DMCC","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["knepublishing.com"],"crossmark-restriction":true},"short-container-title":["JOVR"],"abstract":"<jats:p>Purpose: To evaluate the 1-year effectiveness of selective laser trabeculoplasty (SLT) in patients with pseudoexfoliative glaucoma (PEXG).\nMethods: This prospective, single-arm, non-randomized interventional study involved 40 eyes from 40 patients with PEXG with no history of glaucoma surgery and laser trabeculoplasty. All participants underwent a single session of 360\u00ba SLT. Follow-up visits were conducted at 2 hours, 1 day, 1 week, and at 1, 2, 3, 4, 5, 6, and 12 months after the procedure. The intraocular pressure (IOP), the number of anti-glaucoma medications (NOM), and the 1-year success rate were investigated as primary outcome measures; while the incidence of adverse effects was considered the secondary outcome. Treatment success was defined as a \u226520% decrease in IOP compared to baseline.\nResults: The baseline IOP was 22.19 \u00b1 2.08 mmHg, and the mean NOM was 3.12 \u00b1 0.55 before the SLT procedure. The mean IOP was significantly lower at all follow-up visits than at baseline, whereas the mean NOM remained unchanged throughout the follow-up period. The mean IOP values at 1, 3, 6, and 12 months after SLT were 18.02, 16.92, 16.47, and 15.31 mmHg, respectively. The overall 1-year success rate was 85%, with an average IOP reduction of 31.0% relative to baseline. The most common adverse event following SLT was mild anterior chamber inflammation, which occurred in 32.5% of eyes.\nConclusion: The SLT procedure could significantly reduce IOP in patients with PEXG with minimal adverse effects. The 1-year outcomes were favorable, suggesting that SLT may serve as an effective primary or complementary treatment for PEXG.<\/jats:p>","DOI":"10.18502\/jovr.v21.17046","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T09:04:32Z","timestamp":1771491872000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.18502\/knecrossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["One-year Success Rate of Selective Laser Trabeculoplasty in Pseudoexfoliative Glaucoma: A Prospective Study"],"prefix":"10.18502","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0276-4384","authenticated-orcid":false,"given":"Behzad Fallahi","family":"Motlagh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2249-3075","authenticated-orcid":false,"given":"Amin","family":"Arasteh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5379-4663","authenticated-orcid":false,"given":"Ali","family":"Mostafaie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakimallah","family":"Ghalamara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0209-208X","authenticated-orcid":false,"given":"Farhad","family":"Najafzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7770","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"324591","doi-asserted-by":"crossref","unstructured":"1. 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A population-based survey of the prevalence and types of glaucoma in central Iran: the Yazd eye study. Ophthalmology 2013;120:1977-1984.","DOI":"10.1016\/j.ophtha.2013.02.029"},{"key":"324595","doi-asserted-by":"crossref","unstructured":"5. Barkana Y, Belkin M. Selective laser trabeculoplasty. Surv Ophthalmol 2007;52:634-654.","DOI":"10.1016\/j.survophthal.2007.08.014"},{"key":"324596","doi-asserted-by":"crossref","unstructured":"6. Chen YF, Zeng W. Mechanism of selective laser trabeculoplasty: A systemic review. Int J Ophthalmol 2024;17:963-968.","DOI":"10.18240\/ijo.2024.05.22"},{"key":"324597","doi-asserted-by":"crossref","unstructured":"7. Kennedy JB, SooHoo JR, Kahook MY, Seibold LK. SooHoo JR, Kahook MY, Seibold LK. Selective laser trabeculoplasty: An update. Asia Pac J Ophthalmol 2016;5:63-69.","DOI":"10.1097\/APO.0000000000000175"},{"key":"324598","doi-asserted-by":"crossref","unstructured":"8. Wong MO, Lee JW, Choy BN, Chan JC, Lai JS. Systematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma. Surv Ophthalmol 2015;60:36-50.","DOI":"10.1016\/j.survophthal.2014.06.006"},{"key":"324599","doi-asserted-by":"crossref","unstructured":"9. Takusagawa HL, Hoguet A, Sit AJ, Rosdahl JA, Chopra V, Ou Y, et al. Selective laser trabeculoplasty for the treatment of glaucoma: A report by the American Academy of Ophthalmology. Ophthalmology 2024;131:37-47.","DOI":"10.1016\/j.ophtha.2023.07.029"},{"key":"324600","doi-asserted-by":"crossref","unstructured":"10. Schl\u00f6tzer-Schrehardt U. Pseudoexfoliative glaucoma: Epidemiology, pathophysiology, and clinical implications. In Gillmann K and Mansouri K, eds. The science of glaucoma management. Academic Press; 2023:89-104.","DOI":"10.1016\/B978-0-323-88442-6.00034-0"},{"key":"324601","doi-asserted-by":"crossref","unstructured":"11. Y\u00fcksel N, Tu\u011fan BY. Pseudoexfoliation glaucoma: Clinical presentation and therapeutic options. Turk J Ophthalmol. 2023;53:247.","DOI":"10.4274\/tjo.galenos.2023.76300"},{"key":"324602","doi-asserted-by":"crossref","unstructured":"12. Katsanos A, Konstas AG, Mikropoulos DG, Quaranta L, Voudouragkaki IC, Athanasopoulos GP, et al. A review of the clinical usefulness of selective laser trabeculoplasty in exfoliative glaucoma. Adv Ther 2018;35:619-630.","DOI":"10.1007\/s12325-018-0695-z"},{"key":"324603","doi-asserted-by":"crossref","unstructured":"13. Gazzard G, Konstantakopoulou E, Garway-Heath D, Adeleke M, Vickerstaff V, Ambler G, et al.; LiGHT Trial Study Group. Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial: Six-year results of primary selective laser trabeculoplasty versus eye drops for the treatment of glaucoma and ocular hypertension. Ophthalmology 2023;130:139-151.","DOI":"10.1016\/j.ophtha.2022.09.009"},{"key":"324604","doi-asserted-by":"crossref","unstructured":"14. Chi SC, Kang YN, Hwang DK, Liu CJ. Selective laser trabeculoplasty versus medication for open-angle glaucoma: Systematic review and meta-analysis of randomised clinical trials. Br J Ophthalmol 2020;104:1500- 1507.","DOI":"10.1136\/bjophthalmol-2019-315613"},{"key":"324605","doi-asserted-by":"crossref","unstructured":"15. Song JS, Vianna J, Shuba L, Rafuse P, Nicolela M. Evaluating selective laser trabeculoplasty versus argon laser trabeculoplasty in pseudoexfoliation glaucoma patients. Can J Ophthalmol 2018;53:70-75.","DOI":"10.1016\/j.jcjo.2017.07.004"},{"key":"324606","doi-asserted-by":"crossref","unstructured":"16. Kent SS, Hutnik CM, Birt CM, Damji KF, Harasymowycz P, Si F, et al. A randomized clinical trial of selective laser trabeculoplasty versus argon laser trabeculoplasty in patients with pseudoexfoliation. J Glaucoma 2015;24:344- 347.","DOI":"10.1097\/IJG.0b013e31829e55e4"},{"key":"324607","doi-asserted-by":"crossref","unstructured":"17. Goldenfeld M, Geyer O, Segev E, Kaplan-Messas A, Melamed S. Selective laser trabeculoplasty in uncontrolled pseudoexfoliation glaucoma. Ophthalmic Surg Lasers Imaging 2011;42:390-393.","DOI":"10.3928\/15428877-20110630-01"},{"key":"324608","doi-asserted-by":"crossref","unstructured":"18. Lee JH, Na JH, Chung HJ, Choi JY, Kim MJ. Selective laser trabeculoplasty for medically uncontrolled pseudoexfoliation glaucoma in Korean patients. Korean J Ophthalmol 2021;35:476.","DOI":"10.3341\/kjo.2021.0086"},{"key":"324609","unstructured":"19. Lee SC. Clinical outcomes of selective laser trabeculoplasty in Korean eyes with uncontrolled pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci 2017;58:4975-4975."},{"key":"324610","doi-asserted-by":"crossref","unstructured":"20. Hallaj S, Sinha S, Mehran NA, Morrill AM, Pro MJ, Dale E, et al. Intraocular pressure profile following selective laser trabeculoplasty in pigmentary and primary openangle glaucoma. Eur J Ophthalmol 2024;34:1957-1963.","DOI":"10.1177\/11206721241237305"},{"key":"324611","doi-asserted-by":"crossref","unstructured":"21. Khawaja AP, Campbell JH, Kirby N, Chandwani HS, Keyzor I, Parekh M, et al.; UK Glaucoma Real-World Data Consortium. Real-world outcomes of selective laser trabeculoplasty in the United Kingdom. Ophthalmology 2020;127:748-757.","DOI":"10.1016\/j.ophtha.2019.11.017"},{"key":"324612","doi-asserted-by":"crossref","unstructured":"22. Shibata M, Sugiyama T, Ishida O, Ueki M, Kojima S, Okuda T, et al. Clinical results of selective laser trabeculoplasty in open-angle glaucoma in Japanese eyes: Comparison of 180 degree with 360 degree SLT. J Glaucoma 2012;21:17- 21.","DOI":"10.1097\/IJG.0b013e3181fc8020"},{"key":"324613","doi-asserted-by":"crossref","unstructured":"23. Rasmuson E, Bengtsson B, Lind\u00e9n C, Heijl A, Aspberg J, Andersson-Geimer S, et al. Laser trabeculoplasty in newly diagnosed multi-treated glaucoma patients. Acta Ophthalmol. 2021;99:269-274.","DOI":"10.1111\/aos.14576"},{"key":"324614","doi-asserted-by":"crossref","unstructured":"24. Elahi S, Rao HL, Dumitru A, Mansouri K. Predictors of success in selective laser trabeculoplasty: Data from the Lausanne laser trabeculoplasty registry. J Glaucoma 2020;29:550-555.","DOI":"10.1097\/IJG.0000000000001534"},{"key":"324615","doi-asserted-by":"crossref","unstructured":"25. Sandhu S, Damji KF. Laser management of glaucoma in exfoliation syndrome. J Glaucoma 2018;27:S91\u2013S94.","DOI":"10.1097\/IJG.0000000000000909"},{"key":"324616","doi-asserted-by":"crossref","unstructured":"26. Lindegger DJ, Funk J, Jaggi GP. Long-term effect of selective laser trabeculoplasty on intraocular pressure in pseudoexfoliation glaucoma. Klin Monbl Augenheilkd 2015;232:405-408.","DOI":"10.1055\/s-0034-1396334"},{"key":"324617","unstructured":"27. Miraftabi A, Nilforushan N, Nassiri N, Nouri-Mahdavi K. Selective laser trabeculoplasty in patients with pseudoexfoliative glaucoma vs primary open angle glaucoma: A one-year comparative study. Int J Ophthalmol 2016;9:406."},{"key":"324618","doi-asserted-by":"crossref","unstructured":"28. Weinand FS, Althen F. Long-term clinical results of selective laser trabeculoplasty in the treatment of primary open angle glaucoma. Eur J Ophthalmol 2006;16:100-104.","DOI":"10.1177\/112067210601600116"},{"key":"324619","doi-asserted-by":"crossref","unstructured":"29. Wang NL, Friedman DS, Zhou Q, Guo L, Zhu D, Peng Y, et al. A population-based assessment of 24- hour intraocular pressure among subjects with primary open-angle glaucoma: The Handan Eye Study. Invest Ophthalmol Vis Sci 2011;52:7817-7821.","DOI":"10.1167\/iovs.11-7528"},{"key":"324620","doi-asserted-by":"crossref","unstructured":"30. Terauchi R, Ogawa S, Sotozono A, Noro T, Tatemichi M, Nakano T. 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Ophthalmology 2019;126:1238-1248.","DOI":"10.1016\/j.ophtha.2019.04.012"},{"key":"324627","doi-asserted-by":"crossref","unstructured":"37. Mahdy MAMS. Efficacy and Safety of selective laser trabeculoplasty as a primary procedure for controlling intraocular pressure in primary open angle glaucoma and ocular hypertensive patients. Sultan Qaboos Univ Med J 2008;8:53.","DOI":"10.18295\/2075-0528.2693"},{"key":"324628","doi-asserted-by":"crossref","unstructured":"38. Bettis DI, Whitehead JJ, Farhi P, Zabriskie NA. Intraocular pressure spike and corneal decompensation following selective laser trabeculoplasty in patients with exfoliation glaucoma. J Glaucoma 2016;25:e433\u2013e437.","DOI":"10.1097\/IJG.0000000000000340"}],"container-title":["Journal of Ophthalmic and Vision Research"],"original-title":[],"link":[{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/17046\/31506","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/17046\/31507","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/download\/17046\/31506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T09:07:18Z","timestamp":1771492038000},"score":1,"resource":{"primary":{"URL":"https:\/\/knepublishing.com\/index.php\/JOVR\/article\/view\/17046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,19]]},"references-count":38,"URL":"https:\/\/doi.org\/10.18502\/jovr.v21.17046","relation":{},"ISSN":["2008-322X","2008-2010"],"issn-type":[{"value":"2008-322X","type":"electronic"},{"value":"2008-2010","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,19]]}}}