{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T10:47:39Z","timestamp":1782038859172,"version":"3.54.5"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JTHC"],"abstract":"<jats:p>Atrial fibrillation (AF) is highly prevalent in patients undergoing cardiac surgery, and persistent AF poses significant challenges in postoperative rhythm management. This study investigated whether maintaining high-normal potassium levels (&gt;4.4 mmol\/L) during and after cardiopulmonary bypass (CPB) enhances SR restoration and stability in patients with persistent AF. A prospective observational study of 245 patients undergoing elective cardiac surgery was conducted, with potassium levels maintained above 4.5 mmol\/L during CPB and supplemented postoperatively for 48 hours. Outcomes included SR conversion rates, hemodynamic parameters, and predictors of rhythm stability. Results showed that 87% of patients reverted to SR post-CPB, with 71% maintaining SR at 48 hours. Higher intraoperative potassium levels (mean, 4.54 vs 4.41 mmol\/L; P=.02) significantly predicted successful cardioversion, whereas larger left atrial diameter (67.2 vs 53.8 mm; P&lt;.001) correlated with AF persistence. Hemodynamic stability improved in patients with SR, with lower heart rates, higher mean arterial pressures, and reduced ICU stays (52.5 vs 58.8 h; P&lt;.001). The study concludes that maintaining high-normal potassium levels during and after CPB facilitates SR restoration and short-term stability in patients with persistent AF, improving hemodynamics and reducing ICU dependency. Left atrial enlargement remains a key determinant of AF recurrence. These findings support perioperative potassium optimization as a feasible strategy to enhance postoperative outcomes, warranting further multicenter trials for validation<\/jats:p>","DOI":"10.18502\/jthc.v21i2.21692","type":"journal-article","created":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T07:42:24Z","timestamp":1780818144000},"source":"Crossref","is-referenced-by-count":0,"title":["The Role of High-Normal Potassium Levels in the Maintenance of Sinus Rhythm Following Cardiac Surgery in Patients with Persistent Atrial Fibrillation"],"prefix":"10.18502","author":[{"given":"Kiran Kishor","family":"Pisekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushal","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhawana","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheshta","family":"Sangwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7770","published-online":{"date-parts":[[2026,6,6]]},"container-title":["The Journal of Tehran University Heart Center"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JTHC\/article\/download\/21692\/20155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JTHC\/article\/download\/21692\/20155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T09:51:45Z","timestamp":1782035505000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/JTHC\/article\/view\/21692"},"secondary":[{"URL":"https:\/\/jthc.tums.ac.ir\/index.php\/jthc\/article\/view\/2443","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/jthc.v21i2.21692","relation":{},"ISSN":["2008-2371","1735-8620"],"issn-type":[{"value":"2008-2371","type":"electronic"},{"value":"1735-8620","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,6]]}}}