{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:59:41Z","timestamp":1772110781355,"version":"3.50.1"},"reference-count":0,"publisher":"Knowledge E DMCC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ijph"],"abstract":"<jats:p>Background: Oral squamous cell carcinoma (OSCC) has numerous physical, psychosocial and financial implications, which significantly affect patients' quality of life. We aimed to determine the health-related quality of life (HRQoL) and identify quality of life (QoL) predictors in patients with OSCC.\r\nMethods: We included 64 consecutive patients aged 40 to 80 yr treated for OSCC from Jan to Dec 2021. Health-related QoL was evaluated using the 30-item Cancer Quality of Life Questionnaire (QLQ-C30) and the 35-item Head and Neck Cancer-Quality of Life Questionnaire (QLQ-H&amp;N35). The demographic questionnaire and clinical parameters were also presented.\r\nResults: The functioning scale in the QLQ-C30 questionnaire with the lowest average score was Global health status. The mean QLQ-C30 summary score (80.92 \u00b1 10.4) was higher than the Global health status score (50.5 \u00b1 22.2). In the QLQ-H&amp;N35 questionnaire, the symptoms with highest scores were weight loss, dry mouth, and social eating. Linear regression analysis demonstrated that Global health status score was associated with education level [\u03b2-coefficient = 19.33 (95% CI: 10.7-24.9, P=0.004], alcohol consumption [\u03b2-coefficient=10.04 (95% CI: 4.5-14.8), P=0.023] and invasive surgical procedure [\u03b2-coefficient=22.75 (95% CI: 15.0-30.5), P=0.002]. The QLQ-C30 summary score was associated with living alone [\u03b2-coefficient= -20.05 (95% CI: \u221229.91-(\u221210.21), P=0.018], smoking status [\u03b2-coefficient=4.35 (95% CI: 1.8-6.91), P=0.043] and alcohol consumption [\u03b2-coefficient =4.59 (95% CI: 1.99-7.19), P=0.037].\r\nConclusion: We found several significant predictors of worse perception of HRQoL among patients with OSCC, which may be useful for specific prevention and treatment in order to achieve better QoL.\r\n\u00a0<\/jats:p>","DOI":"10.18502\/ijph.v53i2.14926","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T05:48:15Z","timestamp":1708321695000},"source":"Crossref","is-referenced-by-count":1,"title":["Quality of Life of Patients with Oral Squamous Cell Carcinoma"],"prefix":"10.18502","author":[{"given":"Maja Milosevic","family":"Markovic","sequence":"first","affiliation":[]},{"given":"Milan","family":"Petrovic","sequence":"additional","affiliation":[]},{"given":"Milan","family":"Latas","sequence":"additional","affiliation":[]},{"given":"Igor","family":"Djordjevic","sequence":"additional","affiliation":[]},{"given":"Srdjan","family":"Milovanovic","sequence":"additional","affiliation":[]},{"given":"Svetlana","family":"Jovanovic","sequence":"additional","affiliation":[]}],"member":"7770","published-online":{"date-parts":[[2024,2,18]]},"container-title":["Iranian Journal of Public Health"],"original-title":[],"link":[{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/ijph\/article\/download\/14926\/14044","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/ijph\/article\/download\/14926\/14044","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:01:44Z","timestamp":1772107304000},"score":1,"resource":{"primary":{"URL":"https:\/\/publish.kne-publishing.com\/index.php\/ijph\/article\/view\/14926"},"secondary":[{"URL":"https:\/\/ijph.tums.ac.ir\/index.php\/ijph\/article\/view\/29466","label":"UNIVERSITY"}]},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,18]]},"references-count":0,"URL":"https:\/\/doi.org\/10.18502\/ijph.v53i2.14926","relation":{},"ISSN":["2251-6093","2251-6085"],"issn-type":[{"value":"2251-6093","type":"electronic"},{"value":"2251-6085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,18]]}}}