{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T03:20:45Z","timestamp":1648696845323},"reference-count":29,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"2","license":[{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Colomb. Obstet. Ginecol."],"abstract":"<jats:p>Objetivo: determinar la prevalencia del compromiso ganglionar de pacientes con c\u00e1ncer de endometrio y hacer una exploraci\u00f3n de los factores asociados a la invasi\u00f3n ganglionar. Materiales y m\u00e9todos: estudio de prevalencia con an\u00e1lisis exploratorio. Se incluyeron pacientes con c\u00e1ncer de endometrio llevadas a histerectom\u00eda abdominal total m\u00e1s salpingooforectom\u00eda bilateral y linfadenectom\u00eda p\u00e9lvica, con o sin linfadenectom\u00eda paraa\u00f3rtica en siete centros de oncolog\u00eda de Colombia, en el periodo 2009-2016. Se excluyeron pacientes con radioterapia o quimioterapia previa, diagn\u00f3stico histol\u00f3gico de tumores neuroendocrinos, carcinosarcomas, tumores sincr\u00f3nicos o metacr\u00f3nicos. Muestreo no probabil\u00edstico. Tama\u00f1o muestral n = 290. Variables medidas: sociodemogr\u00e1ficas, cl\u00ednicas e histopatol\u00f3gicas y compromiso ganglionar p\u00e9lvico o paraa\u00f3rtico. Se presenta la prevalencia de periodo; el an\u00e1lisis exploratorio se realiz\u00f3 por medio de odds ratio (OR) crudo y el ajustado mediante un modelo multivariado (regresi\u00f3n log\u00edstica no condicional). Resultados: se obtuvieron 467 casos de los cuales se excluyeron 163 por no presentar la totalidad de las variables, se estudiaron 304 pacientes. La prevalencia del compromiso ganglionar fue del 15,8% (48\/304). Los factores asociados al compromiso ganglionar en el an\u00e1lisis crudo y ajustado fueron la invasi\u00f3n linfovascular (OR ajustado = 9,32; IC 95%: 4,27-21,15) e invasi\u00f3n miometrial (OR ajustado = 3.95; IC 95%: 1,29-14,98). Conclusi\u00f3n: el 15% de las pacientes sometidas a linfadenectom\u00eda tienen compromiso ganglionar. Se deben evaluar alternativas diagn\u00f3sticas menos invasivas que la cirug\u00eda radical para establecer la invasi\u00f3n ganglionar.<\/jats:p>","DOI":"10.18597\/rcog.3450","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T13:01:36Z","timestamp":1594645296000},"source":"Crossref","is-referenced-by-count":0,"title":["Prevalencia del compromiso ganglionar en pacientes con c\u00e1ncer de endometrio, Colombia 2009-2016: an\u00e1lisis exploratorio de factores asociados"],"prefix":"10.18597","volume":"71","author":[{"given":"Robinson Segundo","family":"Fern\u00e1ndez-Mercado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio Arturo","family":"Miranda-Mej\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang\u00e9lica Viviana","family":"Fletcher-Prieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Alexander","family":"Rodr\u00edguez-Gallego","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmundo","family":"Mora-Padilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sim\u00f3n","family":"Orostegui-Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro","family":"Gonz\u00e1lez-Rubio de la Hoz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Alberto","family":"Vallejo-Bertel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"S\u00e1enz-Salazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Alejandra","family":"Fern\u00e1ndez-C\u00e1sseres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen Cecilia","family":"Fl\u00f3rez-Lozano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9dgar","family":"Navarro-Lechuga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2020,5,20]]},"reference":[{"key":"84857","doi-asserted-by":"crossref","unstructured":"Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. 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