{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:53:04Z","timestamp":1747201984600,"version":"3.40.5"},"reference-count":13,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"4","license":[{"start":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T00:00:00Z","timestamp":1609286400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Colomb. Obstet. Ginecol."],"abstract":"<jats:p>Objetivo: reportar el caso de una aplasia eritroide pura secundaria al embarazo y hacer una revisi\u00f3n de la literatura sobre el diagn\u00f3stico, tratamiento y pron\u00f3stico materno y perinatal. Materiales y m\u00e9todos: se presenta el caso de una paciente de 24 a\u00f1os, con embarazo de 34 semanas, remitida a un hospital p\u00fablico de referencia regional por anemia en estudio; se realiza biopsia de m\u00e9dula \u00f3sea sobre la que se hace diagn\u00f3stico de aplasia eritroide pura asociada al embarazo. Recibe manejo con transfusiones seriadas de gl\u00f3bulos rojos; se realiza ces\u00e1rea a t\u00e9rmino, con reci\u00e9n nacido sano; en su puerperio presenta estabilidad de los valores de hemoglobina. Se realiz\u00f3 b\u00fasqueda bibliogr\u00e1fica en las bases de datos electr\u00f3nicas de Medline v\u00eda PubMed, LILACS, SciELO y ScienceDirect, con los t\u00e9rminos \u201cembarazo\u201d, \u201caplasia pura de c\u00e9lulas rojas\u201d, \u201cpregnancy\u201d y \u201cpure red-cell aplasia\u201d. Se incluyeron reportes de caso, series de casos y revisiones bibliogr\u00e1ficas en ingl\u00e9s y espa\u00f1ol, desde enero de 1999 a enero de 2020, de pacientes gestantes con aplasia eritriode pura. Se tom\u00f3 informaci\u00f3n sobre el diagn\u00f3stico, tratamiento y pron\u00f3stico materno y perinatal. Tres autores seleccionaron los estudios por t\u00edtulo y resumen. Se hace s\u00edntesis descriptiva. Resultados: se identificaron 828 t\u00edtulos, de los cuales 818 fueron descartados luego de revisar los criterios de inclusi\u00f3n. Se incluyeron diez art\u00edculos: seis reportes de casos, tres reportes de caso con revisi\u00f3n de la literatura, un reporte de caso en la modalidad de poster, para un total de 10 casos reportados. El diagn\u00f3stico se bas\u00f3 en bajos niveles de hemoglobina y compromiso de la l\u00ednea eritriode en la biopsia de m\u00e9dula. El tratamiento en transfusiones de gl\u00f3bulos rojos y el pron\u00f3stico materno-fetal fueron buenos. Conclusi\u00f3n: el diagn\u00f3stico de la aplasia eritroide pura en el embarazo requiere biopsia de m\u00e9dula. El pron\u00f3stico materno-perinatal es bueno, con soporte transfusional. Se requieren m\u00e1s estudios para evaluar la seguridad y eficacia de los corticosteroides para esta entidad en el embarazo.<\/jats:p>","DOI":"10.18597\/rcog.3543","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T15:19:31Z","timestamp":1609255171000},"page":"365-373","source":"Crossref","is-referenced-by-count":0,"title":["Aplasia eritroide pura secundaria a embarazo: reporte de un caso y revisi\u00f3n de la literatura"],"prefix":"10.18597","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4906-6476","authenticated-orcid":false,"given":"Juan Felipe","family":"Herrera-Quintana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6973-238X","authenticated-orcid":false,"given":"Ana Carolina","family":"Rojas-Figueroa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9143-1006","authenticated-orcid":false,"given":"Rafael Leonardo","family":"Arag\u00f3n-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6652-6991","authenticated-orcid":false,"given":"Roberto","family":"Gallo-Roa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5443-1883","authenticated-orcid":false,"given":"Marcos Fidel","family":"Castillo Zamora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2020,12,30]]},"reference":[{"key":"86421","unstructured":"Mangla A, Hamad H. Pure red cell aplasia. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020. PMID: 31751023."},{"key":"86422","doi-asserted-by":"crossref","unstructured":"Means RT. Pure red cell aplasia. Blood. 2016; 128(21):2504-9. https:\/\/doi.org\/10.1182\/blood-2016-05-717140","DOI":"10.1182\/blood-2016-05-717140"},{"key":"86423","doi-asserted-by":"crossref","unstructured":"Sawada K, Fujishima N, Hirokawa M. Acquired pure red cell aplasia: Updated review of treatment. Br J Haematol. 2008;142(4):505-14. https:\/\/doi.org\/10.1111\/j.1365-2141.2008.07216.x","DOI":"10.1111\/j.1365-2141.2008.07216.x"},{"key":"86424","doi-asserted-by":"crossref","unstructured":"Kashyap R, Pradhan M. Maternal and fetal outcome in pregnancy-associated pure red cell aplasia. J Obstet Gynaecol. 2010;30(7):733-4. https:\/\/doi.org\/10.3109\/01443615.2010.501919","DOI":"10.3109\/01443615.2010.501919"},{"key":"86425","doi-asserted-by":"crossref","unstructured":"Matsui H, Umehara N, Shibata M, Kaneko K, Irie R, Yoshioka T, et al. A case of thymoma complicated pure red cell aplasia and candida funisitis during pregnancy. Placenta. 2017;57:323. https:\/\/doi.org\/10.1016\/j.placenta.2017.07.310","DOI":"10.1016\/j.placenta.2017.07.310"},{"key":"86426","doi-asserted-by":"crossref","unstructured":"Choudry MA, Moffett BK, Laber DA. Pure red-cell aplasia secondary to pregnancy, characterization of a syndrome. Ann Hematol. 2007;86(4):233-7. https:\/\/doi.org\/10.1007\/s00277-006-0211-4","DOI":"10.1007\/s00277-006-0211-4"},{"key":"86427","doi-asserted-by":"crossref","unstructured":"Aggarwal S. Reversible pure red cell aplasia of pregnancy: A therapeutic challenge. 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