{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:14:47Z","timestamp":1766067287494,"version":"3.37.3"},"reference-count":37,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"1","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100007329","name":"Universidad del Valle","doi-asserted-by":"publisher","award":["1852. 208"],"award-info":[{"award-number":["1852. 208"]}],"id":[{"id":"10.13039\/501100007329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Colomb. Obstet. Ginecol."],"abstract":"<jats:p>Objetivo: evaluar la prevalencia de yodo deficiencia y de bocio en mujeres ind\u00edgenas gestantes de cinco \u00e1reas no metropolitanas en Colombia. Materiales y m\u00e9todos: estudio de corte transversal descriptivo. Se incluyeron mujeres embarazadas de cualquier edad gestacional sin condiciones patol\u00f3gicas del embarazo, atendidas en los centros de salud comunitarios o en sus residencias. Se excluyeron aquellas con comorbilidades presentes al momento del embarazo y tambi\u00e9n a quienes recib\u00edan suplementos con yodo. Muestreo aleatorio simple. Se midieron las caracter\u00edsticas sociodemogr\u00e1ficas y obst\u00e9tricas, la concentraci\u00f3n de yodo en orina y la presencia de bocio de acuerdo a la metodolog\u00eda de la Organizaci\u00f3n Mundial de la Salud. Se realiz\u00f3 un an\u00e1lisis descriptivo. Resultados: 189 gestantes ind\u00edgenas fueron candidatas a ingresar al estudio, de las cuales 2 no aceptaron participar y 62 ten\u00edan criterios de exclusi\u00f3n, finalmente se analizaron 125. La concentraci\u00f3n urinaria de yodo tuvo una mediana de 184,4 \u03bcg\/L (min-max: 12,0-390,0). Un total de 42 gestantes (33,6%) ten\u00edan yodo deficiencia (&lt; 100 \u03bcg\/L) y se evidenci\u00f3 bocio (grado 1-2) en 43 (34,4%). No se identific\u00f3 bocio grados 3 o 4. Conclusiones: embarazadas ind\u00edgenas residentes en \u00e1reas no metropolitanas evidenciaron alta prevalencia de bocio y yodo deficiencia. Se requiere evaluar los efectos materno-perinatales e implementar intervenciones nutricionales.<\/jats:p>","DOI":"10.18597\/rcog.3549","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T19:38:01Z","timestamp":1616528281000},"page":"12-23","source":"Crossref","is-referenced-by-count":1,"title":["Prevalencia de bocio y yodo-deficiencia en embarazadas ind\u00edgenas de cinco \u00e1reas no metropolitanas de Colombia 2019"],"prefix":"10.18597","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7190-4707","authenticated-orcid":false,"given":"Juli\u00e1n Alberto","family":"Herrera-Murgueitio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2322-4301","authenticated-orcid":false,"given":"Ana Yiby","family":"Forero-Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7674-0804","authenticated-orcid":false,"given":"Marco Antonio","family":"Tamara-Burgos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0674-1419","authenticated-orcid":false,"given":"Mar\u00eda Marcela","family":"Arriola-Salgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6491-4384","authenticated-orcid":false,"given":"Elia Johanna","family":"G\u00f3mez-Porras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7733-168X","authenticated-orcid":false,"given":"Sandra Ximena","family":"C\u00e9spedes-Gait\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6161-8611","authenticated-orcid":false,"given":"Erika Julieth","family":"Uma\u00f1a-Bautista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5136-4205","authenticated-orcid":false,"given":"Dar\u00edo","family":"Herrera-Murgueitio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7190-4707","authenticated-orcid":false,"given":"Javier","family":"Torres- Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3771-7553","authenticated-orcid":false,"given":"Ana Mar\u00eda","family":"Galvis-Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0792-7119","authenticated-orcid":false,"given":"An\u00edbal","family":"Nieto-D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"key":"86770","doi-asserted-by":"crossref","unstructured":"Mansourian AR. Thyroid function tests during first-trimester of pregnancy: a review of literature. Pakistan J Biol Sci. 2010;13(14):664\u201373. https:\/\/doi.org\/10.3923\/pjbs.2010.664.673","DOI":"10.3923\/pjbs.2010.664.673"},{"key":"86771","unstructured":"Sack J. Thyroid function in pregnancy - maternal-fetal relationship in health and disease. Pediatr Endocrinol Rev. 2003; 1(S2):170\u20136."},{"key":"86772","unstructured":"WHO\/UNICEF\/IICCID. Assesment of iodine deficiency disorders and monitoring their elimination: A guide for programme managers. 3rd ed. Geneva: World Health Organization; 2007. https:\/\/apps.who.int\/iris\/handle\/10665\/43781"},{"key":"86773","unstructured":"Kirgegaard-Klibto DM, Perlev K, Andersen SL, Perrild H, Knudsen N, Weber T, et al. Lodine deficiency in pregnancy is prevalent in vulnerable groups in Denmark. Danish Med J 2016; 63 (11)."},{"key":"86774","doi-asserted-by":"crossref","unstructured":"Fereja M, Gebremedhin S, Gebreegziabher T, Girma M, Stoecker JB. Pregnancy and delivery BMC. Prevalence of iodine deficiency and associated factors among pregnant women in Ada district, Oromia region, Ethiopia: a cross- sectional study. BMC Pregnancy Childbirth. 2018; 1(57): 257. https:\/\/doi.org\/10.1186\/s12884-018-1905-z","DOI":"10.1186\/s12884-018-1905-z"},{"key":"86775","doi-asserted-by":"crossref","unstructured":"Gowachirapant S, Winichagoon P, Wyss L, Tong B, Baumgartner J, Melse-Boonstra A, et al. Urinary iodine concentrations indicate iodine deficiency in pregnant Thai women but iodine sufficiency in their school-aged children. J Nutr. 2009; 139 (6): 1169-72. https:\/\/doi.org\/10.3945\/jn.108.100438","DOI":"10.3945\/jn.108.100438"},{"key":"86776","doi-asserted-by":"crossref","unstructured":"Buzinge Cb, Longo-Mbenza B, kengne AP. The prevalence of insufficient iodine intake in pregnancy in Africa: protocol for a systematic review and meta-analysis. Syst Rev. 2019; 8:209. https:\/\/doi.org\/10.1186\/s13643-019-1092-7","DOI":"10.1186\/s13643-019-1092-7"},{"key":"86777","doi-asserted-by":"crossref","unstructured":"Campos Rde O, Barreto Idos S, Maia LR, Rebou\u00e7as SC, Cerqueira TL, Oliveira CA, et al . Iodine nutritional status in Brazil: a meta-analysis of all studies performed in the country pinpoints to an insufficient evaluation and heterogeneity. Arch Endocrinol Metab. 2015; 59(1):13-22. https:\/\/doi.org\/10.1590\/2359-3997000000004","DOI":"10.1590\/2359-3997000000004"},{"key":"86778","doi-asserted-by":"crossref","unstructured":"Zimmerman MB, Jooste PL, Pandav CS. Iodine deficiency disorders. Lancet. 2008; 372 (9645):1251-62. https:\/\/doi.org\/10.1016\/S0140-6736(08)61005-3","DOI":"10.1016\/S0140-6736(08)61005-3"},{"key":"86779","doi-asserted-by":"crossref","unstructured":"Yadav K, Pandav CS. National Iodine Deficiency Disorders Control Programme: Current status & future strategy. Indian J Med Res. 2018; 148 (5):503-10. https:\/\/doi.org\/10.4103\/ijmr.IJMR_1717_18","DOI":"10.4103\/ijmr.IJMR_1717_18"},{"key":"86780","doi-asserted-by":"crossref","unstructured":"Toloza FJK, Motahary S. Consequences of severe iodine deficiency in pregnancy: evidence in humans. Endocrinol frontal. 2020;11.409. https:\/\/doi.org\/10.3389\/fendo.2020.00409","DOI":"10.3389\/fendo.2020.00409"},{"key":"86781","doi-asserted-by":"crossref","unstructured":"De Escobar GM, Obreg\u00f3n MJ, del Rey FE. Maternal thyroid hormones early in pregnancy and fetal brain development. Best Pract Res Clin Endocrinol Metab. 2004; 18(2):225\u201348. https:\/\/doi.org\/10.1016\/j.beem.2004.03.012","DOI":"10.1016\/j.beem.2004.03.012"},{"key":"86782","doi-asserted-by":"crossref","unstructured":"Melse-Boonstra A, Jaiswal N. Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development. Best Pract Res Clin Endocrinol Metab. 2010;24(1):29\u201338. https:\/\/doi.org\/10.1016\/j.beem.2009.09.002","DOI":"10.1016\/j.beem.2009.09.002"},{"key":"86783","doi-asserted-by":"crossref","unstructured":"Zimmermann MB. The role of iodine in human growth and development. Semin Cell Dev Biol. 2011; 22(6): 645\u20135. https:\/\/doi.org\/10.1016\/j.semcdb.2011.07.009","DOI":"10.1016\/j.semcdb.2011.07.009"},{"key":"86784","doi-asserted-by":"crossref","unstructured":"Nazeri P, Shab-Bidar S, Pearce EN, Shariat M. Do maternal urinary iodine concentration or thyroid hormones within the normal range during pregnancy affect growth parameters at birth? A systematic review and meta-analysis. Nutr Rev. 2020; 78 (9):747-63. https:\/\/doi.org\/10.1093\/nutrit\/nuz105","DOI":"10.1093\/nutrit\/nuz105"},{"key":"86785","unstructured":"Qian M, Wang D, Watkins WE, Gebski V, Yan YQ, Li M, et al. The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China. Asia Pac J Clin Nutr. 2005;14(1):32\u201342."},{"key":"86786","doi-asserted-by":"crossref","unstructured":"Mian C, Vitaliano P, Pozza D, Barollo S, Pitton M, Callegari G, et al. Iodine status in pregnancy: role of dietary habits and geographical origin. Clin Endocrinol 2009; 70(5):776\u2014780. https:\/\/doi.org\/10.1111\/j.1365-2265.2008.03416.x","DOI":"10.1111\/j.1365-2265.2008.03416.x"},{"key":"86787","doi-asserted-by":"crossref","unstructured":"Chittimoju SB, Pearce EN. Iodine deficiency and supplementation in pregnancy. Clin Obstet Gynecol 2019; 62(2):330-8. https:\/\/doi.org\/10.1097\/GRF.0000000000000428","DOI":"10.1097\/GRF.0000000000000428"},{"key":"86788","doi-asserted-by":"crossref","unstructured":"Vanderpas JB, Moreno R. Historical aspects of iodine deficiency control. Minerva Med. 2017; 108 (2):124-35. 20. Donnay S, Arena BJ,b, Lucas AC, Velasco ID, Ares SE. Suplementaci\u00f3n con yodo durante el embarazo y la lactancia. Sociedad Espa\u00f1ola de Endocrinolog\u00eda y Nutrici\u00f3n. Endocr Nutr. 2014; 61:27-34. https:\/\/doi.org\/10.1016\/j.endonu.2013.05.004","DOI":"10.1016\/j.endonu.2013.05.004"},{"key":"86789","doi-asserted-by":"crossref","unstructured":"Anderson M, Benoist B, Delange F, ZuspanJ. Iodine deficiency in Europe: a continuing public health problem. Public Health nutr. 2007; 10(12A):1606-1611. https:\/\/doi.org\/10.1017\/S1368980007361004","DOI":"10.1017\/S1368980007361004"},{"key":"86790","doi-asserted-by":"crossref","unstructured":"Harding KB, Pe\u00f1a-Rosas JP, Webster AC, Yap CM, Payne BA, Ota E, et al. Iodine supplementation for women during the preconception, pregnancy and postpartum period. Cochrane Database Syst Rev. 2017, 3(3): CD011761. https:\/\/doi.org\/10.1002\/14651858.CD011761.pub2","DOI":"10.1002\/14651858.CD011761.pub2"},{"key":"86791","unstructured":"Mora S. Situaci\u00f3n nutricional de yodo, presencia de bocio y funci\u00f3n tiroidea en una poblaci\u00f3n de mujeres embarazadas en la ciudad de Bogot\u00e1. (Colombia). Tesis de maestr\u00eda 2015. Disponible en: https:\/\/www.repositorio.unal.edu.co\/handle\/unal\/52302"},{"key":"86792","doi-asserted-by":"crossref","unstructured":"Singh GR, Davison B, Ma GY, Eastman CJ, Mackerras DE. Iodine status of Indigenous and non-Indigenous young adults in the top end, before and after mandatory fortification. Med J Aust. 2019;210(3):121\u20135. https:\/\/doi.org\/10.5694\/mja2.12031","DOI":"10.5694\/mja2.12031"},{"key":"86793","unstructured":"L\u00f3pez Rodr\u00edguez G, Galv\u00e1n M, Silva Maldonado I, Ch\u00e1vez Dossetti M. Factores asociados al estado nutricional de yodo en preescolares del estado de Hidalgo, M\u00e9xico. G. 2013;149: 141-147. Disponible en: https:\/\/www.anmm.org.mx\/GMM\/2013\/n2\/GMM_149_2013_2_161-167.pdf"},{"key":"86794","unstructured":"Departamento Administrativo Nacional de Estad\u00edstica (DANE) Colombia. Manual de Conceptos. 2018. Disponible en: https:\/\/www.dane.gov.co\/files\/censo2018\/informacion-tecnica\/cnpv-2018-glosario.pdf"},{"key":"86795","doi-asserted-by":"crossref","unstructured":"Pino S, Fang S, Braverman LE. Ammonium persulfate: a safe alternative oxidizing reagent for measuring urinary iodine. Clinical Chemistry. 1996; 42(2): 239-24.","DOI":"10.1093\/clinchem\/42.2.239"},{"key":"86796","doi-asserted-by":"crossref","unstructured":"Zimmermann MB, Hess SY, Molinari L, debenoist B, Delange F, Braverman LE, et al. New reference values for thyroid volume by ultrasound in iodine sufficient school children: A World Health Organization \/ nutrition for health and develeropment iodine deficiency study group report. Am J Clin Nutr. 2004; 79: 231-7. https:\/\/doi.org\/10.1093\/ajcn\/79.2.231","DOI":"10.1093\/ajcn\/79.2.231"},{"key":"86797","doi-asserted-by":"crossref","unstructured":"Gonz\u00e1lez-Fern\u00e1ndez D, Sahajpal R, Chagu\u0308endo JE, Ortiz-Mart\u00ednez RE, Herrera JA, Scott ME, et al. Associations of history of displacement, food insecurity, and stress with maternal-fetal health in a conflict zone: a case study. Frontiers Publ Health. 2020; 8 (319). https:\/\/doi.org\/10.3389\/fpubh.2020.00319","DOI":"10.3389\/fpubh.2020.00319"},{"key":"86798","doi-asserted-by":"crossref","unstructured":"Restrepo-Arango M, Guti\u00e9rrez-Builes L, R\u00edos-Osorio L. Ci\u00eanc. Sa\u00fade Colet Seguridad alimentaria en poblaciones ind\u00edgenas y campesinas: una revisi\u00f3n sistem\u00e1tica 2018; 23(4): 1169-1181. https:\/\/doi.org\/10.1590\/1413-81232018234.13882016","DOI":"10.1590\/1413-81232018234.13882016"},{"key":"86799","unstructured":"FAO, OPS, WFP y UNICEF. 2018. Panorama de la seguridad alimentaria y nutricional en Am\u00e9rica Latina y l Caribe 2018. Santiago. Disponible en: http:\/\/www.fao.org\/3\/ca2127es\/ca2127es.pdf"},{"key":"#cr-split#-86800.1","doi-asserted-by":"crossref","unstructured":"Mundo-Rosas V, Shamah-Levy T, Rivera-Dommarco J, Grupo de Seguridad Alimentaria en M\u00e9xico. Epidemiolog\u00eda de la inseguridad alimentaria en M\u00e9xico. Salud p\u00fablica M\u00e9x. 2013 (supl 2)","DOI":"10.21149\/spm.v55s2.5117"},{"key":"#cr-split#-86800.2","doi-asserted-by":"crossref","unstructured":"55: S206-S213, 2013. https:\/\/doi.org\/10.21149\/spm.v55s2.5117","DOI":"10.21149\/spm.v55s2.5117"},{"key":"86801","unstructured":"Corr\u00eaa EM. Vigil\u00e2ncia epidemiol\u00f3gica da desnutri\u00e7\u00e3o infantil na Regi\u00e3o Norte brasileira de 2008 a 2017. S\u00e3o Paulo; s.n; 2020. 131 p."},{"key":"86802","doi-asserted-by":"crossref","unstructured":"Echagu\u0308e G, Sosa L, D\u00edaz V, Funes P, Rivas L, Granado D, et al. Malnutrici\u00f3n en ni\u00f1os menores de 5 a\u00f1os ind\u00edgenas y no ind\u00edgenas de zonas rurales, Paraguay Mem. Inst. Invest. Cienc. Salud (Impr.). 2016; 14(2): 25-34. https:\/\/doi.org\/10.18004\/Mem.iics\/1812-9528\/2016.014(02)25-034","DOI":"10.18004\/Mem.iics\/1812-9528\/2016.014(02)25-034"},{"key":"86803","doi-asserted-by":"crossref","unstructured":"Mohan V, Sinha RA, Pathak A, Rastogi L, Kumar P, Pal A, et al. Maternal thyroid hormone deficiency affects the fetal neocorticogenesis by reducing the proliferating pool, rate of neurogenesis and indirect neurogenesis. Exp Neurol. 2012;237 (2):477-88. https:\/\/doi.org\/10.1016\/j.expneurol.2012.07.019","DOI":"10.1016\/j.expneurol.2012.07.019"},{"key":"86804","doi-asserted-by":"crossref","unstructured":"Jones SA, Thoemke KR, Anderson GW. The role of thyroid hormone in fetal and neonatal brain development. Curr Opin Endocrinol Diabetes. 2020;12(1):10\u20136. https:\/\/doi.org\/10.1097\/01.med.0000151393.51033.fa","DOI":"10.1097\/01.med.0000151393.51033.fa"},{"key":"86805","doi-asserted-by":"crossref","unstructured":"Zimmermann MB. The role of iodine in human growth and development. Semin Cell Dev Biol. 2011; 22(6): 645\u20135. https:\/\/doi.org\/10.1016\/j.semcdb.2011.07.009","DOI":"10.1016\/j.semcdb.2011.07.009"}],"container-title":["Revista Colombiana de Obstetricia y Ginecolog\u00eda"],"original-title":[],"link":[{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/download\/3549\/3685","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/download\/3549\/3685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T13:13:12Z","timestamp":1618578792000},"score":1,"resource":{"primary":{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/view\/3549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,30]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,3,30]]}},"URL":"https:\/\/doi.org\/10.18597\/rcog.3549","relation":{},"ISSN":["2463-0225","0034-7434"],"issn-type":[{"type":"electronic","value":"2463-0225"},{"type":"print","value":"0034-7434"}],"subject":[],"published":{"date-parts":[[2021,3,30]]}}}