{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:53:06Z","timestamp":1747201986294,"version":"3.40.5"},"reference-count":22,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"3","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Colomb. Obstet. Ginecol."],"abstract":"<jats:p>Objetivo: reportar el caso de una gestante con diagn\u00f3stico ultrasonogr\u00e1fico de alteraci\u00f3n del sistema tegumentario fetal y diagn\u00f3stico posnatal de s\u00edndrome de Omenn.\r\nPresentaci\u00f3n de caso: se presenta el caso de paciente de 27 a\u00f1os con embarazo de 31 semanas, con exploraci\u00f3n ultrasonogr\u00e1fica prenatal que evidencia feto con edema significativo del cuero cabelludo, l\u00edquido amni\u00f3tico ecog\u00e9nico y descamaci\u00f3n de la piel abdominal, con aproximaci\u00f3n diagn\u00f3stica ultrasonogr\u00e1fica de variante de ictiosis. El reci\u00e9n nacido present\u00f3 eritrodermia cong\u00e9nita complicada con infecci\u00f3n de piel, con posterior choque s\u00e9ptico y muerte. El estudio gen\u00e9tico y patol\u00f3gico concluye s\u00edndrome de Omenn.\r\nConclusi\u00f3n: el s\u00edndrome de Omenn debe ser tomado en cuenta en los diagn\u00f3sticos diferenciales cuando en la ultrasonograf\u00eda prenatal existan hallazgos ultrasongr\u00e1ficos de una alteraci\u00f3n del sistema tegumentario. Se requieren estudios que eval\u00faen la exactitud del ultrasonido en el diagn\u00f3stico antenatal de las eritrodermias.<\/jats:p>","DOI":"10.18597\/rcog.3670","type":"journal-article","created":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T20:49:00Z","timestamp":1633466940000},"page":"291-297","source":"Crossref","is-referenced-by-count":2,"title":["Aproximaci\u00f3n diagn\u00f3stica ultrasonogr\u00e1fica prenatal al s\u00edndrome de Omenn: reporte de caso"],"prefix":"10.18597","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5682-5541","authenticated-orcid":false,"given":"Santiago","family":"Aristiz\u00e1bal-Ortiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7593-8197","authenticated-orcid":false,"given":"Alba","family":"Esquivel-Villabona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8522-9207","authenticated-orcid":false,"given":"Yenny Constanza","family":"Bernal-Cifuentes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2021,9,30]]},"reference":[{"key":"87596","doi-asserted-by":"crossref","unstructured":"Sarkar R, Garg S, Garg V. 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