{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:10:23Z","timestamp":1776132623043,"version":"3.50.1"},"reference-count":13,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"2","license":[{"start":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T00:00:00Z","timestamp":1688083200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T00:00:00Z","timestamp":1688083200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["revista.fecolsog.org"],"crossmark-restriction":false},"short-container-title":["Rev. colomb. obstet. ginecol."],"abstract":"<jats:p>Objetivos: describir las caracter\u00edsticas cl\u00ednicas y sociodemogr\u00e1ficas de las gestantes con diagn\u00f3stico de diabetes mellitus gestacional (DMG) y evaluar posibles factores asociados al control gluc\u00e9mico fuera de objetivo y requerimiento de insulina.Materiales y m\u00e9todos: cohorte retrospectiva descriptiva. Se incluyeron mujeres con DMG atendidas en un hospital de referencia entre enero de 2018 y septiembre de 2020; se excluyeron mujeres con parto realizado en otra Instituci\u00f3n. Las variables medidas fueron edad, \u00edndice de masa corporal al inicio del embarazo, antecedentes familiares de diabetes, edad gestacional al diagn\u00f3stico, glucemia basal y glucemia post prueba de tolerancia oral a la glucosa, fructosamina, Hba1c, y uso de insulinoterapia. Se realiz\u00f3 un an\u00e1lisis descriptivo y exploratorio de los factores asociados al mal control gluc\u00e9mico por medio del an\u00e1lisis uni y multivariado.Resultados: el 44 % de las pacientes con DMG presentaron control gluc\u00e9mico fuera de objetivo con medidas higi\u00e9nico-diet\u00e9ticas. El an\u00e1lisis exploratorio mostr\u00f3 que podr\u00eda haber un incremento en el riesgo del mal control gluc\u00e9mico asociado al valor inicial de la glucemia durante la PTOG (OR crudo: 3,57, IC 95 %: 2,1 - 6,1), el IMC &gt; 25 kg\/m2 (OR: 1,97, IC 95 %: 1,15 - 3,34) y la mayor edad gestacional al momento del diagn\u00f3stico como factor protector del requerimiento de la insulinoterapia (OR: 0,45, IC 95 %: 0,27 - 0,75). Sin embargo, estas asociaciones no se confirm\u00f3 en el an\u00e1lisis multivariado.Conclusiones: el valor de la glucemia basal mayor a 95 mg\/dl, el IMC mayor a 25 kg\/m2 podr\u00edan estar asociadas al mal control gluc\u00e9mico en las mujeres con DMG. Se necesitan estudios que eval\u00faen estas variables con control de los factores de confusi\u00f3n para determinar los factores que indican el uso de insulina en mujeres gestantes.<\/jats:p>","DOI":"10.18597\/rcog.3883","type":"journal-article","created":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T17:45:30Z","timestamp":1684259130000},"page":"136-142","update-policy":"https:\/\/doi.org\/10.18597\/crossmark","source":"Crossref","is-referenced-by-count":3,"title":["Factores de riesgo asociados al requerimiento de insulina en pacientes con diabetes gestacional en un hospital de referencia en Buenos Aires, Argentina: estudio de cohorte retrospectiva","Risk factors associated with the need for insulin in patients with gestational diabetes in a reference hospital in Buenos Aires, Argentina: retrospective cohort study"],"prefix":"10.18597","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2682-4601","authenticated-orcid":false,"given":"Melina","family":"Saban","sequence":"first","affiliation":[{"name":"Hospital Brit\u00e1nico, Ciudad Aut\u00f3noma de Buenos Aires (Argentina)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6190-7640","authenticated-orcid":false,"given":"Gabriela","family":"Rovira","sequence":"additional","affiliation":[{"name":"Hospital Brit\u00e1nico, Ciudad Aut\u00f3noma de Buenos Aires (Argentina)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1850-8318","authenticated-orcid":false,"given":"Marina In\u00e9s","family":"Curri\u00e1","sequence":"additional","affiliation":[{"name":"Hospital Brit\u00e1nico, Ciudad Aut\u00f3noma de Buenos Aires (Argentina)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2023,6,30]]},"reference":[{"key":"93054","doi-asserted-by":"crossref","unstructured":"Salzberg S, Alvari\u00f1as J, L\u00f3pez G, Gorban S, Linari A, Falc\u00f3n E, et al. Gu\u00edas de diagn\u00f3stico y tratamiento de diabetes gestacional. Rev. ALAD. 2016;6:155-69. https:\/\/doi.org\/10.47196\/diab.v50i3.45","DOI":"10.47196\/diab.v50i3.45"},{"key":"93055","doi-asserted-by":"crossref","unstructured":"Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan D, et al. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. 2008;358:1991\u20132002. https:\/\/doi.org\/10.1056\/NEJMoa0707943","DOI":"10.1056\/NEJMoa0707943"},{"key":"93056","doi-asserted-by":"crossref","unstructured":"Gorban S, Sucani S, Salzberg S, Alvari\u00f1as J, Faingold C, Jawerbaum A, et al. Prevalence of gestational diabetes mellitus in Argentina according to the Latin American Diabetes Association (ALAD) and International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria and the associated maternal-neonatal complications. Health Care Women Int. 2021;42:636\u2013656. https:\/\/doi.org\/10.1080\/07399332.2020.1800012","DOI":"10.1080\/07399332.2020.1800012"},{"key":"93057","doi-asserted-by":"crossref","unstructured":"Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, et al. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med. 2005;352: 2477\u20132486. https:\/\/doi.org\/10.1056\/NEJMoa042973","DOI":"10.1056\/NEJMoa042973"},{"key":"93058","doi-asserted-by":"crossref","unstructured":"Dabelea D, Hanson RL, Lindsay RS, Pettitt DJ, Imperatore G, Gabir MM, et al. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes. 2000;49:2208\u20132211. https:\/\/doi.org\/10.2337\/diabetes.49.12.2208","DOI":"10.2337\/diabetes.49.12.2208"},{"key":"93059","doi-asserted-by":"crossref","unstructured":"Walker JD. NICE guidance on diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period. NICE clinical guideline 63. London, March 2008. Diabet Med. 2008;25: 1025\u20131027. https:\/\/doi.org\/10.1111\/j.1464-5491.2008.02532.x","DOI":"10.1111\/j.1464-5491.2008.02532.x"},{"key":"93060","doi-asserted-by":"crossref","unstructured":"Russell C, Dodds L, Armson BA, Kephart G, Joseph KS. Diabetes mellitus following gestational diabetes: role of subsequent pregnancy. BJOG. 2008;115: 253\u20139; discussion 260. https:\/\/doi.org\/10.1111\/j.1471-0528.2007.01459.x","DOI":"10.1111\/j.1471-0528.2007.01459.x"},{"key":"93061","doi-asserted-by":"crossref","unstructured":"Sapienza AD, Francisco RPV, Trindade TC, Zugaib M. Factors predicting the need for insulin therapy in patients with gestational diabetes mellitus. Diabetes Res Clin Pract. 2010;88:81\u201386. https:\/\/doi.org\/10.1016\/j.diabres.2009.12.023","DOI":"10.1016\/j.diabres.2009.12.023"},{"key":"93062","unstructured":"Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines. Weight Gain During Pregnancy: Reexamining the Guidelines. Rasmussen KM, Yaktine AL, editors. Washington (DC): National Academies Press (US); 2009."},{"key":"93063","doi-asserted-by":"crossref","unstructured":"ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al. 15. Management of diabetes in pregnancy: Standards of care in diabetes-2023. Diabetes Care. 2023;46:S254\u2013S266. https:\/\/doi.org\/10.2337\/dc23-S015","DOI":"10.2337\/dc23-S015"},{"key":"93064","doi-asserted-by":"crossref","unstructured":"Akinci B, Celtik A, Yener S, Yesil S. Is fasting glucose level during oral glucose tolerance test an indicator of the insulin need in gestational diabetes? 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