{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T14:52:32Z","timestamp":1776783152459,"version":"3.51.2"},"reference-count":44,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["revista.fecolsog.org"],"crossmark-restriction":false},"short-container-title":["Rev. colomb. obstet. ginecol."],"abstract":"<jats:p>Objetivo: desarrollar un marco conceptual que permita la interpretaci\u00f3n de los gases arteriales y venosos, as\u00ed como los par\u00e1metros de perfusi\u00f3n en mujeres gestantes, integrando las adaptaciones fisiol\u00f3gicas del embarazo para favorecer la toma de decisiones cl\u00ednicas.\nMateriales y m\u00e9todos: a partir de un caso hipot\u00e9tico, que ilustra de manera pr\u00e1ctica el tema, se desarrolla un documento explicativo en el que se analizan los principales cambios fisiol\u00f3gicos del embarazo que afectan la interpretaci\u00f3n de los gases arteriales y venosos, tales como la hiperventilaci\u00f3n inducida por progesterona, responsable de una alcalosis respiratoria compensada. Asimismo, se abordan las adaptaciones hemodin\u00e1micas y de perfusi\u00f3n materna, la oxigenaci\u00f3n fetal y sus implicaciones cl\u00ednicas.\nResultados: en el embarazo se producen un conjunto de cambios fisiol\u00f3gicos que impactan la homeostasis materna y fetal, con subsecuentes modificaciones en los gases arteriales y venosos, as\u00ed como en los par\u00e1metros de perfusi\u00f3n. Cambios a nivel respiratorio, como el aumento del consumo de ox\u00edgeno, del volumen minuto y del volumen corriente, son responsables de la disminuci\u00f3n de los niveles de PaCO\u2082, lo que da lugar a una alcalosis respiratoria compensada y, de manera secundaria, a un aumento del pH arterial. A nivel hemodin\u00e1mico, se observa un aumento progresivo del gasto cardiaco y una disminuci\u00f3n de la resistencia vascular perif\u00e9rica, lo que resulta en una circulaci\u00f3n de alto volumen y baja resistencia, propia de un estado hiperdin\u00e1mico. Estos aspectos son claves a la hora de brindar atenci\u00f3n a la paciente obst\u00e9trica cr\u00edticamente enferma.\nConclusiones: Hay limitaciones en el conocimiento actual respecto a la interpretaci\u00f3n de los gases arteriales como indicadores de la funci\u00f3n respiratoria y la perfusi\u00f3n de los tejidos en la mujer gestante, como tambi\u00e9n respecto a la interacci\u00f3n entre la oxigenaci\u00f3n materna, fetal y la perfusi\u00f3n placentaria, especialmente en situaciones de estr\u00e9s critico o a nivel de grandes alturas. Por ahora, los par\u00e1metros de interpretaci\u00f3n derivados de mujeres no gestantes deben guiar la atenci\u00f3n de la gestante con complicaciones serias. Se requieren estudios que caractericen de mejor manera los cambios que presenta la mujer gestante cr\u00edticamente enferma, a la luz de los cambios fisiol\u00f3gicos que acompa\u00f1an el embarazo para una m\u00e1s adecuada interpretaci\u00f3n de los gases arteriales y venosos como indicadores de ventilaci\u00f3n y perfusi\u00f3n tisular de la madre, el feto y la placenta.<\/jats:p>","DOI":"10.18597\/rcog.4357","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T19:03:41Z","timestamp":1769540621000},"update-policy":"https:\/\/doi.org\/10.18597\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Evaluando el estado \u00e1cido-base y la perfusi\u00f3n: gases arteriales y venosos durante la gestaci\u00f3n","Evaluating acid\u2013base status and perfusion: arterial and venous blood gases during pregnancy"],"prefix":"10.18597","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3015-1320","authenticated-orcid":false,"given":"Daniel","family":"Molano Franco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0579-5186","authenticated-orcid":false,"given":"Antonio","family":"Viruez-Soto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3219-5792","authenticated-orcid":false,"given":"Yuliana","family":"Luna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7913","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"105755","doi-asserted-by":"crossref","unstructured":"Blechner J. 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