{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:54:08Z","timestamp":1786550048318,"version":"build-2736575974"},"reference-count":17,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"2","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100007329","name":"Universidad del Valle","doi-asserted-by":"publisher","award":["Convocatoria 166- 2024, CI 11319"],"award-info":[{"award-number":["Convocatoria 166- 2024, CI 11319"]}],"id":[{"id":"10.13039\/501100007329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["revista.fecolsog.org"],"crossmark-restriction":false},"short-container-title":["Rev. colomb. obstet. ginecol."],"abstract":"<jats:p>Objetivo: estimar la prevalencia de infecci\u00f3n por virus de la hepatitis B (VHB), virus de la hepatitis C (VHC) y virus linfotr\u00f3pico humano de c\u00e9lulas T tipo 1 (HTLV-1) mediante panel ampliado en mujeres embarazadas atendidas en dos ciudades de Colombia, 2024-2025, y describir la clasificaci\u00f3n serol\u00f3gica obtenida con el triple panel para VHB. \nMateriales y m\u00e9todos: estudio transversal descriptivo realizado en mujeres embarazadas atendidas en tres instituciones de primer nivel de Cali y Buenaventura entre el 1 de junio de 2024 y el 30 de junio de 2025. La selecci\u00f3n se hizo mediante muestreo consecutivo. Se aplic\u00f3 el panel ampliado, que incluy\u00f3 ant\u00edgeno de superficie del VHB, anticuerpos contra el ant\u00edgeno de superficie y contra el n\u00facleo total, anticuerpos contra VHC con confirmaci\u00f3n mediante ARN viral, y anticuerpos contra HTLV-1 con confirmaci\u00f3n por Western Blot. Se realiz\u00f3 an\u00e1lisis descriptivo y se estim\u00f3 la prevalencia de periodo.\nResultados: se evaluaron 320 mujeres para criterios de elegibilidad; 305 firmaron consentimiento informado, respondieron un cuestionario estructurado, tuvieron muestras completas y fueron incluidas en el an\u00e1lisis final. La mediana de edad fue de 26 a\u00f1os y la mediana de edad gestacional de 22 semanas. La prevalencia de HTLV-1 fue de 1,6 % y la infecci\u00f3n activa por virus de la hepatitis C del 0,7 %. Para el virus de la hepatitis B la prevalencia de infecci\u00f3n aguda fue del 0,3 %, y para la infecci\u00f3n cr\u00f3nica reagudizada fue del 0,7 %. El 70,25 % eran mujeres susceptibles de la infecci\u00f3n, 84 con inmunidad atribuible a vacunaci\u00f3n (27,5 %) y 4 con infecci\u00f3n resuelta (1,3 %).\nConclusiones: la alta susceptibilidad a la infecci\u00f3n VHB es un problema que deber\u00eda ser abordado desde una pol\u00edtica p\u00fablica que tenga en cuenta la revisi\u00f3n del estado vacunal y la vacunaci\u00f3n durante el control prenatal. Se requieren estudios de implementaci\u00f3n que eval\u00faen la factibilidad, aceptabilidad, costo-efectividad e impacto cl\u00ednico y program\u00e1tico del panel ampliado para VHB, VHC y HTLV-1 en la atenci\u00f3n prenatal.<\/jats:p>","DOI":"10.18597\/rcog.4645","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T13:20:27Z","timestamp":1786454427000},"page":"e4645","update-policy":"https:\/\/doi.org\/10.18597\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["Prevalencia de hepatitis B, hepatitis C y HTLV-1 mediante el uso del panel ampliado en mujeres embarazadas de dos ciudades de Colombia, 2024-2025","Prevalence of Hepatitis B, Hepatitis C, and HTLV-1 Using an Expanded Testing Panel Among Pregnant Women in Two Cities in Colombia, 2024-2025"],"prefix":"10.18597","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4704-2171","authenticated-orcid":false,"given":"Juan Pablo","family":"Rojas-Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Universidad del Valle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3770-4058","authenticated-orcid":false,"given":"M\u00f3nica Alexandra","family":"Gil-Artunduaga","sequence":"additional","affiliation":[{"name":"Universidad Libre Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9733-3757","authenticated-orcid":false,"given":"Nathalia","family":"Cort\u00e9s","sequence":"additional","affiliation":[{"name":"Universidad Libre Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6945-8261","authenticated-orcid":false,"given":"Herney Andr\u00e9s","family":"Garc\u00eda Perdomo","sequence":"additional","affiliation":[{"name":"Universidad del Valle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0794-4093","authenticated-orcid":false,"given":"Ludy","family":"Vargas Torres","sequence":"additional","affiliation":[{"name":"Pedagogical and Technological University of Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7913","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"107833","doi-asserted-by":"crossref","unstructured":"1. 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Nota t\u00e9cnica sobre buenas pr\u00e1cticas para prevenir la transmisi\u00f3n maternoinfantil del virus linfotr\u00f3pico humano de c\u00e9lulas T tipo 1. Washington, D.C.: OPS; 2024."},{"key":"107840","unstructured":"8. Ministerio de Salud y Protecci\u00f3n Social. Resoluci\u00f3n 3280 de 2018. Colombia."},{"key":"107841","doi-asserted-by":"crossref","unstructured":"9. Abbasi F, Almukhtar M, Fazlollahpour-Naghibi A, Alizadeh F, Behzad Mogha-dam K, Jafari Tadi M, et al. Hepatitis C infection seroprevalence in pregnant women worldwide: A systematic review and meta-analysis. EClin Med. 2023;66:102327. https:\/\/doi.org\/10.1016\/j.eclinm.2023.102327","DOI":"10.1016\/j.eclinm.2023.102327"},{"key":"107842","doi-asserted-by":"crossref","unstructured":"10. S\u00e1nchez-N\u00fa\u00f1ez J, de-Miguel-Balsa E, Soriano V, Lorenzo-Garrido E, Gim\u00e9nez-Richarte A, Otero-Rodr\u00edguez S, et al. Prevalence of HTLV-1\/2 infection in pregnant women in Central and South America and the Caribbean: A systematic review and meta-analysis. Int J Infect Dis. 2024;143:107018. https:\/\/doi.org\/10.1016\/j.ijid.2024.107018","DOI":"10.1016\/j.ijid.2024.107018"},{"key":"107843","doi-asserted-by":"crossref","unstructured":"11. Cort\u00e9s Buelvas A, Beltr\u00e1n M, Gallego G, Isaza L. Estudio prospectivo seroepidemiol\u00f3gico de infecci\u00f3n por el virus linfotr\u00f3pico humano I y II (HTLV-I\/II) en donantes de sangre de \u00e1reas colombianas end\u00e9micas y no end\u00e9micas. Colomb Med. 1999;30(1):19-25. https:\/\/doi.org\/10.25100\/cm.v30i.1.117","DOI":"10.25100\/cm.v30i.1.117"},{"key":"107844","doi-asserted-by":"crossref","unstructured":"12. Blank A, Yamaguchi K, Blank M, Lourido M, Takatsuki K. HTLV-II detection in an Amerindian family in Colombian southern Andean region. 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Paraparesia esp\u00e1stica tropical \/ mielopat\u00eda asociada a HTLV (PET\/MAH): reporte de casos en el Pac\u00edfico colombiano. Rev Fac Cienc Salud Univ Cauca. 2013;15(3):31-40."},{"key":"107848","doi-asserted-by":"crossref","unstructured":"16. Ram\u00edrez C, Duque E, Levin A, Pantoja M, Blattner W. Neoplasias de c\u00e9lulas T y virus HTLV-I en el suroccidente colombiano. Colomb Med. 1989;20(2):38-41. https:\/\/doi.org\/10.25100\/cm.v20i2.6246","DOI":"10.25100\/cm.v20i2.6246"},{"key":"107849","doi-asserted-by":"crossref","unstructured":"17. Wu S, Wang J, Guo Q, Lan H, Sun Y, Ren M, et al. Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: A systematic review and meta-analysis. 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