{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:54:13Z","timestamp":1786550053244,"version":"build-2736575974"},"reference-count":27,"publisher":"Federacion Colombiana de Obstetricia y Ginecologia","issue":"2","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["revista.fecolsog.org"],"crossmark-restriction":false},"short-container-title":["Rev. colomb. obstet. ginecol."],"abstract":"<jats:p>Objetivo: presentar un caso cli\u0301nico de si\u0301ndrome de eritrocitosis miomatosa (SEM), y revisar la literatura sobre su diagno\u0301stico y tratamiento.\n\n\n\n\nMateriales y me\u0301todos: se describe el caso de una paciente de 45 an\u0303os, quien consulto\u0301 por hemorragia uterina a un hospital general de media complejidad, que atiende pacientes ginecolo\u0301gicas con patologi\u0301as benignas y urgencias ginecobste\u0301tricas, se hizo diagno\u0301stico de miomatosis uterina y policitemia. Fue sometida a histerectomi\u0301a con resolucio\u0301n de la eritrocitosis a los 42 di\u0301as en el posoperatorio. Se realizo\u0301 una revisio\u0301n de la literatura mediante bu\u0301squeda en las bases de datos: MedLine, Embase y LILACS, utilizando te\u0301rminos MeSH y DeCS relacionados; se incluyeron reportes y series de casos de mujeres con SEM, y se busco\u0301 informacio\u0301n sobre el diagno\u0301stico y tratamiento en publicaciones en ingle\u0301s y espan\u0303ol de los u\u0301ltimos 20 an\u0303os.\n\n\n\n\nResultados: se identificaron 29 ti\u0301tulos en las bases de datos mencionadas, de los cuales 17 cumplieron los criterios de inclusio\u0301n: 15 reportes de caso y 2 series de casos que, en conjunto, describieron 20 pacientes con SEM. Los si\u0301ntomas ma\u0301s frecuentes fueron el aumento progresivo del taman\u0303o de la masa abdominal, dolor pe\u0301lvico y hemorragia uterina anormal (35%). El ultrasonido fue la te\u0301cnica de imagen diagno\u0301stica ma\u0301s utilizada, se encontraron pocos estudios de biologi\u0301a molecular y hormonas. La histerectomi\u0301a fue el tratamiento ma\u0301s comu\u0301n, con resolucio\u0301n completa de la eritrocitocitosis en todos los casos con seguimiento disponible. Los reportes de complicaciones de esta condicio\u0301n son pocos.\n\n\n\n\n\n\n\n\nConclusiones: el SEM debe considerarse en el diagno\u0301stico diferencial de mujeres con policitemia no explicada y miomatosis. La histerectomi\u0301a constituye el tratamiento definitivo, con posterior normalizacio\u0301n de los para\u0301metros hematolo\u0301gicos. Se requieren ma\u0301s estudios que permitan comprender mejor su fisiopatologi\u0301a y sus complicaciones, asi\u0301 como evaluar otras alternativas terape\u0301uticas.\n\n\n\n\n\u00a0<\/jats:p>","DOI":"10.18597\/rcog.4653","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:46:28Z","timestamp":1785422788000},"page":"e4653","update-policy":"https:\/\/doi.org\/10.18597\/crossmark","source":"Crossref","is-referenced-by-count":0,"title":["S\u00edndrome de eritrocitosis miomatosa: reporte de caso y revisi\u00f3n de la literatura","Myomatous erythrocytosis syndrome: Case report and literature review"],"prefix":"10.18597","volume":"77","author":[{"given":"Giovanni Enrique","family":"Ria\u00f1o Castellanos","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/059yx9a68","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Nacional de Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernarda Jinneth","family":"Acosta Forero","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/059yx9a68","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Nacional de Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2229-1569","authenticated-orcid":false,"given":"Laura Lorena","family":"Leuro Mosquera","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/059yx9a68","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Nacional de Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0724-5617","authenticated-orcid":false,"given":"Daniela Valentina","family":"Afanador Jaimes","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7913","published-online":{"date-parts":[[2026,7,14]]},"reference":[{"key":"107614","doi-asserted-by":"crossref","unstructured":"1. 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Erythropoietin and erythropoietin receptor system in a large uterine myoma of a patient with myomatous erythrocytosis syndrome: Possible relationship with the pathogenesis of unusual tumor size. Hum Pathol. 2005;36(1):120-7. https:\/\/doi.org\/10.1016\/j.humpath.2004.10.009","DOI":"10.1016\/j.humpath.2004.10.009"},{"key":"107618","doi-asserted-by":"crossref","unstructured":"5. Kohama T, Shinohara K, Takahura M, Inoue M. Large uterinemyomawitherythropoietinmessengerRNAand erythrocytosis. Obstet Gynecol. 2000;96(5 Pt 2):826-8. https:\/\/doi.org\/10.1016\/s0029-7844(00)00952-2","DOI":"10.1097\/00006250-200011001-00013"},{"key":"107619","doi-asserted-by":"crossref","unstructured":"6. Yokoyama Y, Shinohara A, Hirokawa M, Maeda N. Erythrocytosis due to an erythropoietin- producing large uterine leiomyoma. Gynecol Obstet Invest. 2003;56(4):179-83. https:\/\/doi.org\/10.1159\/000074104","DOI":"10.1159\/000074104"},{"key":"107620","doi-asserted-by":"crossref","unstructured":"7. Suzuki M, Takamizawa S, Nomaguchi K, Suzu S, Yamada M, Igarashi T, et al. Erythropoietin synthesis by tumour tissues in a patient with uterine myoma and erythrocytosis. Br J Haematol. 2001;113(1):49-51. https:\/\/doi.org\/10.1046\/j.1365-2141.2001.02682.x","DOI":"10.1046\/j.1365-2141.2001.02682.x"},{"key":"107621","doi-asserted-by":"crossref","unstructured":"8. Narita F, Ohara N , Fukunaga K . Myomatouserythrocytosis syndrome. J Obstet Gynaecol. 2003;23(5):577. https:\/\/doi.org\/10.1080\/0144361031000156654","DOI":"10.1080\/0144361031000156654"},{"key":"107622","doi-asserted-by":"crossref","unstructured":"9. Valente E, Zueger M, Donato D. A rare case of venous sinus thrombosis and pulmonary embolisms secondary to myomatous erythrocytosis syndrome. AJOG Glob Rep. 2024;4(2):100340. https:\/\/doi.org\/10.1016\/j.xagr.2024.100340","DOI":"10.1016\/j.xagr.2024.100340"},{"key":"107623","doi-asserted-by":"crossref","unstructured":"10. Guo Q, Qian C, Wang X, Qian Z. Transferrin receptors. 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Case Rep Obstet Gynecol. 2023;2023:7520453. https:\/\/doi.org\/10.1155\/2023\/7520453","DOI":"10.1155\/2023\/7520453"},{"key":"107627","doi-asserted-by":"crossref","unstructured":"14. Mui J, Yang M, Cohen T, McDonald D, Hunt H. More than a myoma: A review of myomatous erythrocytosis syndrome. J Obstet Gynaecol Can. 2020;42(2):198- 203.e3. https:\/\/doi.org\/10.1016\/j.jogc.2018.12.025","DOI":"10.1016\/j.jogc.2018.12.025"},{"key":"107628","doi-asserted-by":"crossref","unstructured":"15. Wang S, Chen Y, Shih Y, Chen M, Lu C. Case report: Myomatous erythrocytosis syndrome presenting as rapid growth of an extra-uterine mass. Front Surg. 2022;9:950358. https:\/\/doi.org\/10.3389\/fsurg.2022.950358","DOI":"10.3389\/fsurg.2022.950358"},{"key":"107629","doi-asserted-by":"crossref","unstructured":"16. Abdul N, Ismail M, Nik N, Daud K, Abu G. Huge uterine fibroid in a postmenopausal woman associated with polycythaemia: A case report. Maturitas. 2008;60(2):177-9. https:\/\/doi.org\/10.1016\/j.maturitas.2008.03.013","DOI":"10.1016\/j.maturitas.2008.03.013"},{"key":"107630","unstructured":"17. Vlasveld L, de Wit C, Verweij R, Castel A, Jansen P, Peters A. Myomatous erythrocytosis syndrome: Further proof for the pathogenic role of erythropoietin. Neth J Med. 2008;66(7)."},{"key":"107631","doi-asserted-by":"crossref","unstructured":"18. Shu X, Chen N, Chen B, Yang H, Bi H. Myomatous erythrocytosis syndrome: A case report. World J Clin Cases. 2022;10(10):3206-12. https:\/\/doi.org\/10.12998\/wjcc.v10.i10.3206","DOI":"10.12998\/wjcc.v10.i10.3206"},{"key":"107632","doi-asserted-by":"crossref","unstructured":"19. Gordon B, Fischbeck T, Salamo R, Schroff S. Treating myomatous erythrocytosis syndrome with uterine artery embolization. Obstet Gynecol. 2019;133(6):1274-7. https:\/\/doi.org\/10.1097\/AOG.0000000000003289","DOI":"10.1097\/AOG.0000000000003289"},{"key":"107633","doi-asserted-by":"crossref","unstructured":"20. 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Myomatous erythrocytosis syndrome-an uncommon cause of secondary polycythemia. Ann Hematol. 2023;102(8):2275-6. https:\/\/doi.org\/10.1007\/s00277-023-05176-8","DOI":"10.1007\/s00277-023-05176-8"},{"key":"107637","doi-asserted-by":"crossref","unstructured":"24. Couillandre P, Lewalle P, Benghiat S, Salaroli A. Surprising erythrocytosis resolution after myomectomy: Myomatous erythrocytosis syndrome. Eur J Case Rep Intern Med. 2023;10(3). https:\/\/doi.org\/10.12890\/2023_003722","DOI":"10.12890\/2023_003722"},{"key":"107638","doi-asserted-by":"crossref","unstructured":"25. Gonza\u0301lez-Paredes G, Labastida C, Uzca\u0301tegui-Paz E. Si\u0301ndrome miomatoso eritrocitario. Reporte de 2 casos. Prog Obstet Ginecol. 2009;52(2):112-7. https:\/\/doi.org\/10.1016\/S0304-5013(09)70345-0","DOI":"10.1016\/S0304-5013(09)70345-0"},{"key":"107639","doi-asserted-by":"crossref","unstructured":"26. de Guzman G, Manalo E. Myomatous erythrocytosis syndrome: A case series. 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Cureus. 2020;12(2):e6892. https:\/\/doi.org\/10.7759\/cureus.6892","DOI":"10.7759\/cureus.6892"}],"container-title":["Revista Colombiana de Obstetricia y Ginecolog\u00eda"],"original-title":[],"link":[{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/download\/4653\/4147","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/download\/4653\/4147","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:12:36Z","timestamp":1786547556000},"score":1,"resource":{"primary":{"URL":"https:\/\/revista.fecolsog.org\/index.php\/rcog\/article\/view\/4653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,14]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,7,16]]}},"URL":"https:\/\/doi.org\/10.18597\/rcog.4653","relation":{},"ISSN":["2463-0225","0034-7434"],"issn-type":[{"value":"2463-0225","type":"electronic"},{"value":"0034-7434","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,14]]},"assertion":[{"value":"2026-07-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer Reviewed","group":{"name":"peer_review","label":"Peer Review"}},{"value":"Federaci\u00f3n Colombiana de Obstetricia y Ginecolog\u00eda","name":"publisher","label":"This article is maintained by"},{"value":"Revista Colombiana de Osbtetricia y Ginecolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"Reporte de Caso","name":"content_type","label":"Content Type"}]}}