{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T05:04:27Z","timestamp":1775279067227,"version":"3.50.1"},"reference-count":41,"publisher":"Impact Journals, LLC","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2016,12,6]]},"DOI":"10.18632\/aging.101119","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T17:20:58Z","timestamp":1481131258000},"page":"3311-3320","source":"Crossref","is-referenced-by-count":22,"title":["Association between genetic variants in the XPG gene and gastric cancer risk in a Southern Chinese population"],"prefix":"10.18632","volume":"8","author":[{"given":"Rui-Xi","family":"Hua","sequence":"first","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"},{"name":"Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen-Jian","family":"Zhuo","sequence":"additional","affiliation":[{"name":"School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong 999077, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinhong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Molecular Epidemiology Laboratory and Department of Laboratory Medicine, Harbin Medical University Cancer Hospital, Harbin 150040, Heilongjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan-Hua","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080,Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Qiong","family":"Xue","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Dan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang-Bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi-Zhao","family":"Li","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Fen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Hua","family":"Jia","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo-Ping","family":"Shen","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"},{"name":"Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"He","sequence":"additional","affiliation":[{"name":"Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Department of Experimental Research, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, China"},{"name":"Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2016,12,6]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"E359","DOI":"10.1002\/ijc.29210","article-title":"Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.","volume":"13","author":"Bray","year":"2015","journal-title":"Int J Cancer"},{"key":"2","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012.","volume":"6","author":"Jemal","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Amedei A, Benagiano M, della Bella C, Niccolai E, D\u2019Elios MM. Novel immunotherapeutic strategies of gastric cancer treatment. J Biomed Biotechnol. 2011; 2011:437348. 10.1155\/2011\/437348","DOI":"10.1155\/2011\/437348"},{"key":"4","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1111\/j.1440-1746.2009.06188.x","article-title":"Epidemiology of Helicobacter pylori infection and gastric cancer in Asia.","volume":"2","author":"Ang","year":"2010","journal-title":"J Gastroenterol Hepatol"},{"key":"5","doi-asserted-by":"publisher","first-page":"794","DOI":"10.3109\/00365521.2013.799221","article-title":"The prevalence of Helicobacter pylori infection in the Netherlands.","volume":"4","author":"Kuipers","year":"2013","journal-title":"Scand J Gastroenterol"},{"key":"6","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1093\/ije\/31.3.624","article-title":"Relation of adult lifestyle and socioeconomic factors to the prevalence of Helicobacter pylori infection.","volume":"3","author":"Leeds","year":"2002","journal-title":"Int J Epidemiol"},{"key":"7","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1093\/annonc\/mdn536","article-title":"Dietary intake of selected micronutrients and gastric cancer risk: an Italian case-control study.","volume":"2","author":"La Vecchia","year":"2009","journal-title":"Ann Oncol"},{"key":"8","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/978-1-61779-612-8_26","article-title":"Multifactorial etiology of gastric cancer.","volume":"86","author":"Zabaleta","year":"2012","journal-title":"Methods Mol Biol"},{"key":"9","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1136\/gutjnl-2015-309168","article-title":"Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.","volume":"6","author":"Nitti","year":"2015","journal-title":"Gut"},{"key":"10","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1126\/science.1056154","article-title":"Human DNA repair genes.","volume":"29","author":"Lindahl","year":"2001","journal-title":"Science"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.10553","article-title":"Identification of biomarkers for pseudo and true progression of GBM based on radiogenomics study.","author":"Zhou","year":"2016","journal-title":"Oncotarget"},{"key":"12","doi-asserted-by":"publisher","first-page":"589","DOI":"10.2174\/1566524033479456","article-title":"Genomic instability and cancer.","volume":"3","author":"Bapat","year":"2003","journal-title":"Curr Mol Med"},{"key":"13","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1021\/cr040483f","article-title":"Molecular mechanisms of mammalian global genome nucleotide excision repair.","volume":"10","author":"Sch\u00e4rer","year":"2006","journal-title":"Chem Rev"},{"key":"14","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/S0921-8777(99)00047-6","article-title":"Replication of damaged DNA: molecular defect in xeroderma pigmentosum variant cells.","volume":"43","author":"Fuchs","year":"1999","journal-title":"Mutat Res"},{"key":"15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0923-1811(99)00088-2","article-title":"Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum.","volume":"2","author":"Cleaver","year":"2000","journal-title":"J Dermatol Sci"},{"key":"16","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/363182a0","article-title":"Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2.","volume":"36","author":"Clarkson","year":"1993","journal-title":"Nature"},{"key":"17","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/carcin\/bgm282","article-title":"Xeroderma pigmentosum genes: functions inside and outside DNA repair.","volume":"2","author":"Sugasawa","year":"2008","journal-title":"Carcinogenesis"},{"key":"18","doi-asserted-by":"publisher","first-page":"16030","DOI":"10.1074\/jbc.272.25.16030","article-title":"The non-catalytic function of XPG protein during dual incision in human nucleotide excision repair.","volume":"27","author":"Sancar","year":"1997","journal-title":"J Biol Chem"},{"key":"19","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.lungcan.2008.11.014","article-title":"Polymorphisms in XRCC1 and XPG and response to platinum-based chemotherapy in advanced non-small cell lung cancer patients.","volume":"6","author":"Yingfeng","year":"2009","journal-title":"Lung Cancer"},{"key":"20","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.lungcan.2011.12.002","article-title":"Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and\/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinum.","volume":"7","author":"Isla","year":"2012","journal-title":"Lung Cancer"},{"key":"21","doi-asserted-by":"publisher","first-page":"e35970","DOI":"10.1371\/journal.pone.0035970","article-title":"The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies.","volume":"7","author":"Yu","year":"2012","journal-title":"PLoS One"},{"key":"22","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1007\/s00439-012-1152-8","article-title":"Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations.","volume":"13","author":"Li","year":"2012","journal-title":"Hum Genet"},{"key":"23","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1111\/jcmm.12773","article-title":"Association between XPG polymorphisms and stomach cancer susceptibility in a Chinese population.","volume":"2","author":"Zhou","year":"2016","journal-title":"J Cell Mol Med"},{"key":"24","doi-asserted-by":"publisher","first-page":"6269","DOI":"10.7314\/APJCP.2012.13.12.6269","article-title":"SNPs of excision repair cross complementing group 5 and gastric cancer risk in Chinese populations.","volume":"1","author":"Zhang","year":"2012","journal-title":"Asian Pac J Cancer Prev"},{"key":"25","doi-asserted-by":"publisher","first-page":"e41500","DOI":"10.1371\/journal.pone.0041500","article-title":"Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS One"},{"key":"26","doi-asserted-by":"publisher","first-page":"6700","DOI":"10.1038\/srep06700","article-title":"Association study between XPG Asp1104His polymorphism and colorectal cancer risk in a Chinese population.","volume":"4","author":"Zhu","year":"2014","journal-title":"Sci Rep"},{"key":"27","doi-asserted-by":"publisher","first-page":"11724","DOI":"10.18632\/oncotarget.7352","article-title":"XPG rs2296147 T>C polymorphism predicted clinical outcome in colorectal cancer.","volume":"7","author":"Jia","year":"2016","journal-title":"Oncotarget"},{"key":"28","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.7150\/jca.15602","article-title":"XPG gene polymorphisms contribute to colorectal cancer susceptibility: a two-stage case-control study.","volume":"7","author":"Jia","year":"2016","journal-title":"J Cancer"},{"key":"29","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1111\/jcmm.12836","article-title":"Association of potentially functional variants in the XPG gene with neuroblastoma risk in a Chinese population.","volume":"2","author":"Xia","year":"2016","journal-title":"J Cell Mol Med"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Washington K. 7th edition of the AJCC cancer staging manual: stomach. Ann Surg Oncol. 2010; 17(12):3077-3079.","DOI":"10.1245\/s10434-010-1362-z"},{"key":"31","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/978-0-387-09599-8_9","article-title":"XPG: its products and biological roles.","volume":"63","author":"Sch\u00e4rer","year":"2008","journal-title":"Adv Exp Med Biol"},{"key":"32","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1126\/science.7801121","article-title":"Transcription-coupled repair and human disease.","volume":"26","author":"Hanawalt","year":"1994","journal-title":"Science"},{"key":"33","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/S0092-8674(02)00795-X","article-title":"Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome.","volume":"10","author":"Prakash","year":"2002","journal-title":"Cell"},{"key":"34","doi-asserted-by":"publisher","first-page":"12566","DOI":"10.1038\/srep12566","article-title":"Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity.","volume":"5","author":"Zhou","year":"2015","journal-title":"Sci Rep"},{"key":"35","doi-asserted-by":"publisher","first-page":"7986","DOI":"10.1038\/srep07986","article-title":"Association between PLCE1 rs2274223 A > G polymorphism and cancer risk: proof from a meta-analysis.","volume":"5","author":"Zheng","year":"2015","journal-title":"Sci Rep"},{"key":"36","doi-asserted-by":"publisher","first-page":"254","DOI":"10.18632\/genesandcancer.63","article-title":"PSCA s2294008 C>T and rs2976392 G>A polymorphisms contribute to cancer susceptibility: evidence from published studies.","volume":"6","author":"Li","year":"2015","journal-title":"Genes Cancer"},{"key":"37","doi-asserted-by":"publisher","first-page":"9420","DOI":"10.18632\/oncotarget.7137","article-title":"PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population.","volume":"7","author":"Wang","year":"2016","journal-title":"Oncotarget"},{"key":"38","doi-asserted-by":"publisher","first-page":"42661","DOI":"10.18632\/oncotarget.6124","article-title":"Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population.","volume":"6","author":"Jin","year":"2015","journal-title":"Oncotarget"},{"key":"39","doi-asserted-by":"publisher","first-page":"15930","DOI":"10.18632\/oncotarget.7527","article-title":"Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population.","volume":"7","author":"Wang","year":"2016","journal-title":"Oncotarget"},{"key":"40","doi-asserted-by":"publisher","first-page":"5513","DOI":"10.2147\/OTT.S113055","article-title":"Polymorphisms in the XPC gene and gastric cancer susceptibility in a Southern Chinese population.","volume":"9","author":"Jia","year":"2016","journal-title":"Onco Targets Ther"},{"key":"41","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1007\/s13277-015-3936-7","article-title":"Evaluation of GWAS-identified SNPs at 6p22 with neuroblastoma susceptibility in a Chinese population.","volume":"3","author":"Xia","year":"2016","journal-title":"Tumour Biol"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.101119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T16:34:24Z","timestamp":1599064464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.101119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,6]]},"references-count":41,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12,31]]}},"alternative-id":["101119","27929383"],"URL":"https:\/\/doi.org\/10.18632\/aging.101119","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,6]]}}}