{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T21:53:44Z","timestamp":1775339624779,"version":"3.50.1"},"reference-count":51,"publisher":"Impact Journals, LLC","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2020,3,3]]},"DOI":"10.18632\/aging.102894","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T19:07:10Z","timestamp":1583262430000},"page":"4424-4444","source":"Crossref","is-referenced-by-count":30,"title":["Discovery and validation of the prognostic value of the lncRNAs encoding snoRNAs in patients with clear cell renal cell carcinoma"],"prefix":"10.18632","volume":"12","author":[{"given":"Wuping","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaifang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoan","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanqing","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kan","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Hereditary Kidney Cancer Research Center, Peking University First Hospital, Beijing 100034, P.R. China"},{"name":"Institute of Urology, Peking University, Beijing 100034, P.R. China"},{"name":"National Urological Cancer Center, Beijing 100034, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2020,3,3]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1186\/1756-0500-5-246","article-title":"RCDB: Renal Cancer Gene Database.","volume":"5","author":"Ramana","year":"2012","journal-title":"BMC Res Notes"},{"key":"2","doi-asserted-by":"publisher","first-page":"17009","DOI":"10.1038\/nrdp.2017.9","article-title":"Renal cell carcinoma.","volume":"3","author":"Ficarra","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"3","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1056\/NEJMra1601333","article-title":"Systemic Therapy for Metastatic Renal-Cell Carcinoma.","volume":"37","author":"Motzer","year":"2017","journal-title":"N Engl J Med"},{"key":"4","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1038\/ng.2699","article-title":"Integrated molecular analysis of clear-cell renal cell carcinoma.","volume":"4","author":"Kon","year":"2013","journal-title":"Nat Genet"},{"key":"5","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.semcancer.2012.06.002","article-title":"The metabolic basis of kidney cancer.","volume":"2","author":"Ricketts","year":"2013","journal-title":"Semin Cancer Biol"},{"key":"6","doi-asserted-by":"publisher","first-page":"JCO2018792549","DOI":"10.1200\/JCO.2018.79.2549","article-title":"Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.","volume":"3","author":"Cheng","year":"2018","journal-title":"J Clin Oncol"},{"key":"7","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.cell.2009.02.006","article-title":"Evolution and functions of long noncoding RNAs.","volume":"13","author":"Reik","year":"2009","journal-title":"Cell"},{"key":"8","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1038\/nm.3981","article-title":"The emerging role of lncRNAs in cancer.","volume":"2","author":"Huarte","year":"2015","journal-title":"Nat Med"},{"key":"9","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.tcb.2017.11.008","article-title":"Long Noncoding RNA in Cancer: Wiring Signaling Circuitry.","volume":"2","author":"Yang","year":"2018","journal-title":"Trends Cell Biol"},{"key":"10","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1038\/nrg2521","article-title":"Long non-coding RNAs: insights into functions.","volume":"1","author":"Mattick","year":"2009","journal-title":"Nat Rev Genet"},{"key":"11","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s12943-017-0681-0","article-title":"Long noncoding RNA MRCCAT1 promotes metastasis of clear cell renal cell carcinoma via inhibiting NPR3 and activating p38-MAPK signaling.","volume":"1","author":"Wang","year":"2017","journal-title":"Mol Cancer"},{"key":"12","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12943-019-0998-y","article-title":"A positive feed-forward loop between LncRNA-URRCC and EGFL7\/P-AKT\/FOXO3 signaling promotes proliferation and metastasis of clear cell renal cell carcinoma.","volume":"1","author":"Xue","year":"2019","journal-title":"Mol Cancer"},{"key":"13","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0955-0674(97)80005-1","article-title":"Function and synthesis of small nucleolar RNAs.","volume":"9","author":"Kiss","year":"1997","journal-title":"Curr Opin Cell Biol"},{"key":"14","doi-asserted-by":"publisher","first-page":"D220","DOI":"10.1093\/nar\/gkz884","article-title":"snoDB: an interactive database of human snoRNA sequences, abundance and interactions.","volume":"4","author":"Scott","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"15","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1016\/S0092-8674(00)81308-2","article-title":"Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs.","volume":"8","author":"Kiss","year":"1996","journal-title":"Cell"},{"key":"16","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1186\/1476-4598-9-198","article-title":"Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer.","volume":"9","author":"Jiang","year":"2010","journal-title":"Mol Cancer"},{"key":"17","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1038\/onc.2011.304","article-title":"Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer.","volume":"3","author":"Jenster","year":"2012","journal-title":"Oncogene"},{"key":"18","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1038\/sj.bjc.6606076","article-title":"The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis.","volume":"10","author":"Harris","year":"2011","journal-title":"Br J Cancer"},{"key":"19","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.ebiom.2017.07.009","article-title":"SNORA21 - An Oncogenic Small Nucleolar RNA, with a Prognostic Biomarker Potential in Human Colorectal Cancer.","volume":"2","author":"Goel","year":"2017","journal-title":"EBioMedicine"},{"key":"20","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1136\/gutjnl-2015-309359","article-title":"Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.","volume":"6","author":"Goel","year":"2017","journal-title":"Gut"},{"key":"21","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1186\/s12943-019-1079-y","article-title":"Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the mA reader YTHDF3.","volume":"1","author":"Li","year":"2019","journal-title":"Mol Cancer"},{"key":"22","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.canlet.2018.03.038","article-title":"Long non-coding RNA SNHG15 interacts with and stabilizes transcription factor Slug and promotes colon cancer progression.","volume":"42","author":"Zhang","year":"2018","journal-title":"Cancer Lett"},{"key":"23","doi-asserted-by":"publisher","first-page":"e3092","DOI":"10.1038\/cddis.2017.484","article-title":"Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression.","volume":"8","author":"Wang","year":"2017","journal-title":"Cell Death Dis"},{"key":"24","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1177\/1758834012443725","article-title":"Novel agents in renal carcinoma: a reality check.","volume":"4","author":"Rini","year":"2012","journal-title":"Ther Adv Med Oncol"},{"key":"25","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s12943-019-0942-1","article-title":"Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt\/\u03b2-catenin signaling pathway.","volume":"1","author":"Zhang","year":"2019","journal-title":"Mol Cancer"},{"key":"26","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1038\/nrc3195","article-title":"Are snoRNAs and snoRNA host genes new players in cancer?","volume":"1","author":"Farzaneh","year":"2012","journal-title":"Nat Rev Cancer"},{"key":"27","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1038\/nrc.2017.104","article-title":"Ribosome biogenesis in cancer: new players and therapeutic avenues.","volume":"1","author":"Volarevi\u0107","year":"2018","journal-title":"Nat Rev Cancer"},{"key":"28","doi-asserted-by":"publisher","first-page":"1833","DOI":"10.1038\/onc.2009.21","article-title":"c-Myc induces changes in higher order rDNA structure on stimulation of quiescent cells.","volume":"2","author":"Wright","year":"2009","journal-title":"Oncogene"},{"key":"29","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s12943-018-0894-x","article-title":"The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p.","volume":"1","author":"Wang","year":"2018","journal-title":"Mol Cancer"},{"key":"30","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1186\/s13046-019-1177-0","article-title":"LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells.","volume":"3","author":"Sun","year":"2019","journal-title":"J Exp Clin Cancer Res"},{"key":"31","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.omtn.2019.06.008","article-title":"Gene Amplification-Driven Long Noncoding RNA SNHG17 Regulates Cell Proliferation and Migration in Human Non-Small-Cell Lung Cancer.","volume":"1","author":"Wang","year":"2019","journal-title":"Mol Ther Nucleic Acids"},{"key":"32","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.semcancer.2018.06.004","article-title":"Challenges and opportunities in the proteomic characterization of clear cell renal cell carcinoma (ccRCC): A critical step towards the personalized care of renal cancers.","volume":"5","author":"Chan","year":"2019","journal-title":"Semin Cancer Biol"},{"key":"33","doi-asserted-by":"publisher","first-page":"3101","DOI":"10.1200\/JCO.2005.04.8280","article-title":"Renal cell carcinoma recurrence after nephrectomy for localized disease: predicting survival from time of recurrence.","volume":"2","author":"Russo","year":"2006","journal-title":"J Clin Oncol"},{"key":"34","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.3892\/or.2017.5837","article-title":"The long non-coding RNA SNHG3 functions as a competing endogenous RNA to promote malignant development of colorectal cancer.","volume":"3","author":"Yuan","year":"2017","journal-title":"Oncol Rep"},{"key":"35","doi-asserted-by":"publisher","first-page":"367","DOI":"10.3233\/CBM-170710","article-title":"Upregulation of SNHG3 expression associated with poor prognosis and enhances malignant progression of ovarian cancer.","volume":"2","author":"Wang","year":"2018","journal-title":"Cancer Biomark"},{"key":"36","doi-asserted-by":"publisher","first-page":"108695","DOI":"10.1016\/j.biopha.2019.108695","article-title":"LncRNA SNHG3\/miRNA-151a-3p\/RAB22A axis regulates invasion and migration of osteosarcoma.","volume":"11","author":"Chen","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"37","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1007\/s13277-015-4052-4","article-title":"SNHG3 correlates with malignant status and poor prognosis in hepatocellular carcinoma.","volume":"3","author":"Liu","year":"2016","journal-title":"Tumour Biol"},{"key":"38","doi-asserted-by":"publisher","first-page":"111595","DOI":"10.1016\/j.yexcr.2019.111595","article-title":"LncRNA SNHG3 promotes clear cell renal cell carcinoma proliferation and migration by upregulating TOP2A.","volume":"38","author":"Liu","year":"2019","journal-title":"Exp Cell Res"},{"key":"39","doi-asserted-by":"publisher","first-page":"7032","DOI":"10.1002\/jcp.27456","article-title":"Aberrant expression of long noncoding RNA SNHG15 correlates with liver metastasis and poor survival in colorectal cancer.","volume":"23","author":"Dong","year":"2019","journal-title":"J Cell Physiol"},{"key":"40","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1038\/s41419-018-0975-1","article-title":"LncRNA SNHG15 acts as a ceRNA to regulate YAP1-Hippo signaling pathway by sponging miR-200a-3p in papillary thyroid carcinoma.","volume":"9","author":"Zheng","year":"2018","journal-title":"Cell Death Dis"},{"key":"41","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s12929-017-0353-9","article-title":"LncRNA SNHG15 contributes to proliferation, invasion and autophagy in osteosarcoma cells by sponging miR-141.","volume":"2","author":"Zheng","year":"2017","journal-title":"J Biomed Sci"},{"key":"42","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1186\/s13046-019-1169-0","article-title":"SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF.","volume":"3","author":"Huarte","year":"2019","journal-title":"J Exp Clin Cancer Res"},{"key":"43","doi-asserted-by":"publisher","first-page":"384","DOI":"10.3892\/ijo.2018.4395","article-title":"Knockdown of SNHG15 suppresses renal cell carcinoma proliferation and EMT by regulating the NF-\u03baB signaling pathway.","volume":"5","author":"Yu","year":"2018","journal-title":"Int J Oncol"},{"key":"44","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1002\/1878-0261.12439","article-title":"Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe-Dnmts axis.","volume":"1","author":"Keil","year":"2019","journal-title":"Mol Oncol"},{"key":"45","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1080\/15592294.2019.1595998","article-title":"Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.","volume":"1","author":"Alwers","year":"2019","journal-title":"Epigenetics"},{"key":"46","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s13148-019-0619-z","article-title":"Discovery and validation of DNA methylation markers for overall survival prognosis in patients with thymic epithelial tumors.","volume":"1","author":"Wang","year":"2019","journal-title":"Clin Epigenetics"},{"key":"47","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s13148-019-0664-7","article-title":"Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk.","volume":"1","author":"Jones","year":"2019","journal-title":"Clin Epigenetics"},{"key":"48","doi-asserted-by":"publisher","first-page":"8","DOI":"10.7554\/eLife.43024","article-title":"Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer.","volume":"8","author":"Kim","year":"2019","journal-title":"eLife"},{"key":"49","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s13148-019-0666-5","article-title":"DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.","volume":"1","author":"Bohrer","year":"2019","journal-title":"Clin Epigenetics"},{"key":"50","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1158\/1078-0432.CCR-18-3230","article-title":"Epigenetic Silencing of miRNA-338-5p and miRNA-421 Drives SPINK1-Positive Prostate Cancer.","volume":"2","author":"Ateeq","year":"2019","journal-title":"Clin Cancer Res"},{"key":"51","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1186\/s13046-018-0924-y","article-title":"Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis.","volume":"3","author":"Zhou","year":"2018","journal-title":"J Exp Clin Cancer Res"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.102894","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T20:05:02Z","timestamp":1599077102000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.102894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,3]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,3,15]]}},"alternative-id":["102894","32126023"],"URL":"https:\/\/doi.org\/10.18632\/aging.102894","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,3]]}}}