{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:11:58Z","timestamp":1791389518529,"version":"4.3.3"},"reference-count":66,"publisher":"Impact Journals, LLC","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2021,1,31]]},"DOI":"10.18632\/aging.202192","type":"journal-article","created":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T12:51:49Z","timestamp":1607691109000},"page":"1989-2014","source":"Crossref","is-referenced-by-count":23,"title":["Screening and functional prediction of differentially expressed circular RNAs in human glioma of different grades"],"prefix":"10.18632","volume":"13","author":[{"given":"Xiuchao","family":"Geng","sequence":"first","affiliation":[{"name":"Faculty of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, PR China"},{"name":"Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050091, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine, Hebei University, Baoding 071000, PR China"},{"name":"Department of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Li","sequence":"additional","affiliation":[{"name":"Faculty of Acupuncture-Moxibustion and Tuina, Hebei University of Chinese Medicine, Shijiazhuang 050200, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Xi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Yu","sequence":"additional","affiliation":[{"name":"Faculty of Acupuncture-Moxibustion and Tuina, Hebei University of Chinese Medicine, Shijiazhuang 050200, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Shi","sequence":"additional","affiliation":[{"name":"Endoscope Room, Department of General Surgery, Cangzhou Central Hospital, Cangzhou 061001, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomeng","family":"Lin","sequence":"additional","affiliation":[{"name":"Departments of Breast Surgery, Affiliated Hospital of Hebei University, Baoding 071000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoguang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Key Laboratory of Medical Biotechnology of Hebei Province, Hebei Medical University, Shijiazhuang 050017, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[{"name":"Faculty of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050091, PR China"},{"name":"Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease, Hebei University of Chinese Medicine, Shijiazhuang 050091, PR China"},{"name":"School of Clinical Medicine, Hebei University, Baoding 071000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 world health organization classification of tumors of the central nervous system: a summary.","volume":"13","author":"Ellison","year":"2016","journal-title":"Acta Neuropathol"},{"key":"2","doi-asserted-by":"publisher","first-page":"3099","DOI":"10.1002\/jcb.29577","article-title":"Identification of genes related to low-grade glioma progression and prognosis based on integrated transcriptome analysis.","volume":"12","author":"Li","year":"2020","journal-title":"J Cell Biochem"},{"key":"3","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1080\/15476286.2015.1020271","article-title":"Regulation of circRNA biogenesis.","volume":"1","author":"Yang","year":"2015","journal-title":"RNA Biol"},{"key":"4","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.canlet.2015.06.003","article-title":"Circular RNA: a new star of noncoding RNAs.","volume":"36","author":"Li","year":"2015","journal-title":"Cancer Lett"},{"key":"5","doi-asserted-by":"publisher","first-page":"11","DOI":"10.20892\/j.issn.2095-3941.2018.0425","article-title":"Circular RNAs and human glioma.","volume":"1","author":"Zhang","year":"2019","journal-title":"Cancer Biol Med"},{"key":"6","doi-asserted-by":"publisher","first-page":"267","DOI":"10.2217\/epi-2019-0295","article-title":"Circular RNA: biogenesis, degradation, functions and potential roles in mediating resistance to anticarcinogens.","volume":"1","author":"Wang","year":"2020","journal-title":"Epigenomics"},{"key":"7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.canlet.2020.03.002","article-title":"Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.","volume":"47","author":"Kang","year":"2020","journal-title":"Cancer Lett"},{"key":"8","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1093\/neuonc\/noz128","article-title":"CircFOXO3 promotes glioblastoma progression by acting as a competing endogenous RNA for NFAT5.","volume":"2","author":"Qiu","year":"2019","journal-title":"Neuro Oncol"},{"key":"9","doi-asserted-by":"publisher","first-page":"4812","DOI":"10.1158\/0008-5472.CAN-18-0532","article-title":"CircNT5E acts as a sponge of miR-422a to promote glioblastoma tumorigenesis.","volume":"7","author":"Liang","year":"2018","journal-title":"Cancer Res"},{"key":"10","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.2217\/epi-2019-0121","article-title":"Circ_0001730 promotes proliferation and invasion via the miR-326\/Wnt7B axis in glioma cells.","volume":"1","author":"Huang","year":"2019","journal-title":"Epigenomics"},{"key":"11","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1186\/s13046-019-1376-8","article-title":"circPTN sponges miR-145-5p\/miR-330-5p to promote proliferation and stemness in glioma.","volume":"3","author":"Ke","year":"2019","journal-title":"J Exp Clin Cancer Res"},{"key":"12","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/s12943-020-01203-8","article-title":"Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression.","volume":"1","author":"Huang","year":"2020","journal-title":"Mol Cancer"},{"key":"13","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s12943-019-1120-1","article-title":"Circular RNA MAPK4 (circ-MAPK4) inhibits cell apoptosis via MAPK signaling pathway by sponging miR-125a-3p in gliomas.","volume":"1","author":"Liu","year":"2020","journal-title":"Mol Cancer"},{"key":"14","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.pharmthera.2018.01.010","article-title":"Circular RNA and its mechanisms in disease: from the bench to the clinic.","volume":"18","author":"Yao","year":"2018","journal-title":"Pharmacol Ther"},{"key":"15","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1038\/s41388-017-0019-9","article-title":"A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis.","volume":"3","author":"Zhang","year":"2018","journal-title":"Oncogene"},{"key":"16","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1186\/s13046-020-01706-8","article-title":"m6A modification in RNA: biogenesis, functions and roles in gliomas.","volume":"3","author":"Wang","year":"2020","journal-title":"J Exp Clin Cancer Res"},{"key":"17","doi-asserted-by":"publisher","first-page":"5785","DOI":"10.1158\/0008-5472.CAN-18-2868","article-title":"N-methyladenosine modulates nonsense-mediated mRNA decay in human glioblastoma.","volume":"7","author":"Chen","year":"2019","journal-title":"Cancer Res"},{"key":"18","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1038\/cr.2017.31","article-title":"Extensive translation of circular RNAs driven by N-methyladenosine.","volume":"2","author":"Wang","year":"2017","journal-title":"Cell Res"},{"key":"19","doi-asserted-by":"publisher","first-page":"E325","DOI":"10.1073\/pnas.1717794115","article-title":"ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells.","volume":"11","author":"Yan","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"key":"20","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1038\/s41422-020-0279-8","article-title":"mA-dependent biogenesis of circular RNAs in male germ cells.","volume":"3","author":"Wang","year":"2020","journal-title":"Cell Res"},{"key":"21","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.biopsych.2020.02.018","article-title":"N-methyladenosine modification of fatty acid amide hydrolase messenger RNA in circular RNA STAG1-regulated astrocyte dysfunction and depressive-like behaviors.","volume":"8","author":"Yao","year":"2020","journal-title":"Biol Psychiatry"},{"key":"22","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1186\/s12859-018-2304-1","article-title":"CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers.","volume":"1","author":"Feng","year":"2018","journal-title":"BMC Bioinformatics"},{"key":"23","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1038\/nature11993","article-title":"Natural RNA circles function as efficient microRNA sponges.","volume":"49","author":"Kjems","year":"2013","journal-title":"Nature"},{"key":"24","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1161\/CIRCULATIONAHA.117.029004","article-title":"Circular noncoding RNA HIPK3 mediates retinal vascular dysfunction in diabetes mellitus.","volume":"13","author":"Yan","year":"2017","journal-title":"Circulation"},{"key":"25","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3892\/ijo.2020.5049","article-title":"Advances in circular RNAs and their role in glioma (review).","volume":"5","author":"Wang","year":"2020","journal-title":"Int J Oncol"},{"key":"26","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1186\/s12943-019-1056-5","article-title":"A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1.","volume":"1","author":"Zhang","year":"2019","journal-title":"Mol Cancer"},{"key":"27","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.2217\/epi-2018-0023","article-title":"Screening circular RNA related to chemotherapeutic resistance in osteosarcoma by RNA sequencing.","volume":"1","author":"Tai-Cheng","year":"2018","journal-title":"Epigenomics"},{"key":"28","doi-asserted-by":"publisher","first-page":"e87","DOI":"10.1093\/nar\/gkw075","article-title":"Circular RNA profile in gliomas revealed by identification tool UROBORUS.","volume":"4","author":"Lu","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"29","doi-asserted-by":"publisher","first-page":"8057","DOI":"10.1038\/srep08057","article-title":"Correlation of circular RNA abundance with proliferation\u2014exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues.","volume":"5","author":"Pils","year":"2015","journal-title":"Sci Rep"},{"key":"30","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/s12943-019-1031-1","article-title":"Circular RNA circTRIM33-12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression.","volume":"1","author":"Fan","year":"2019","journal-title":"Mol Cancer"},{"key":"31","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1186\/s12943-018-0908-8","article-title":"Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p\/G3BP2\/SRC\/FAK axis.","volume":"1","author":"Huang","year":"2018","journal-title":"Mol Cancer"},{"key":"32","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/s12943-019-1025-z","article-title":"Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626\/EYA4 axis.","volume":"1","author":"Huang","year":"2019","journal-title":"Mol Cancer"},{"key":"33","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s12943-020-01205-6","article-title":"circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p\/PIK3R1\/VEGF-C axis in pancreatic cancer.","volume":"1","author":"Chen","year":"2020","journal-title":"Mol Cancer"},{"key":"34","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.cell.2020.08.009","article-title":"Targeting mitochondria-located circRNA SCAR alleviates NASH via reducing mROS output.","volume":"18","author":"Su","year":"2020","journal-title":"Cell"},{"key":"35","doi-asserted-by":"publisher","first-page":"e108","DOI":"10.1161\/CIRCRESAHA.119.316061","article-title":"The tumor-suppressive human circular RNA CircITCH sponges miR-330-5p to ameliorate doxorubicin-induced cardiotoxicity through upregulating SIRT6, survivin, and SERCA2a.","volume":"12","author":"Cao","year":"2020","journal-title":"Circ Res"},{"key":"36","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1111\/iwj.13265","article-title":"Approaches to the treatment of pilonidal sinus disease, clinical practice in 2019.","volume":"1","author":"Ramanathan","year":"2020","journal-title":"Int Wound J"},{"key":"37","doi-asserted-by":"publisher","first-page":"3369","DOI":"10.3892\/ol.2020.11449","article-title":"Exosomal circular RNA sorting mechanisms and their function in promoting or inhibiting cancer.","volume":"1","author":"Wang","year":"2020","journal-title":"Oncol Lett"},{"key":"38","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1038\/onc.2013.97","article-title":"Tax-interacting protein 1 coordinates the spatiotemporal activation of Rho GTPases and regulates the infiltrative growth of human glioblastoma.","volume":"3","author":"Han","year":"2014","journal-title":"Oncogene"},{"key":"39","doi-asserted-by":"publisher","first-page":"392","DOI":"10.3390\/cancers11030392","article-title":"Targeting the mDia formin-assembled cytoskeleton is an effective anti-invasion strategy in adult high-grade glioma patient-derived neurospheres.","volume":"1","author":"Eisenmann","year":"2019","journal-title":"Cancers (Basel)"},{"key":"40","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.1038\/mt.2016.103","article-title":"Role of HCP5-miR-139-RUNX1 feedback loop in regulating Malignant behavior of glioma cells.","volume":"2","author":"Liu","year":"2016","journal-title":"Mol Ther"},{"key":"41","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1038\/s41419-019-2108-x","article-title":"RUNX1 contributes to the mesenchymal subtype of glioblastoma in a TGF\u03b2 pathway-dependent manner.","volume":"1","author":"Kang","year":"2019","journal-title":"Cell Death Dis"},{"key":"42","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3892\/or.2018.6450","article-title":"Microarray analysis of circular RNA expression profiles associated with gemcitabine resistance in pancreatic cancer cells.","volume":"4","author":"Ding","year":"2018","journal-title":"Oncol Rep"},{"key":"43","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s12943-017-0719-3","article-title":"Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression.","volume":"1","author":"Zhu","year":"2017","journal-title":"Mol Cancer"},{"key":"44","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12943-019-0969-3","article-title":"Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression.","volume":"1","author":"Sun","year":"2019","journal-title":"Mol Cancer"},{"key":"45","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1016\/j.jhep.2018.01.012","article-title":"Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma.","volume":"6","author":"Zhou","year":"2018","journal-title":"J Hepatol"},{"key":"46","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1186\/s13059-019-1685-4","article-title":"Translation of the circular RNA circ\u03b2-catenin promotes liver cancer cell growth through activation of the Wnt pathway.","volume":"2","author":"Zhang","year":"2019","journal-title":"Genome Biol"},{"key":"47","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1002\/hep.29270","article-title":"Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression.","volume":"6","author":"Cao","year":"2017","journal-title":"Hepatology"},{"key":"48","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.canlet.2018.04.035","article-title":"Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338\/MACC1\/MET pathway in pancreatic cancer.","volume":"43","author":"Li","year":"2018","journal-title":"Cancer Lett"},{"key":"49","doi-asserted-by":"publisher","first-page":"3806","DOI":"10.18632\/aging.101674","article-title":"Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation.","volume":"1","author":"Liu","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"50","doi-asserted-by":"publisher","first-page":"411","DOI":"10.2217\/epi-2018-0111","article-title":"Circular RNA expression in exosomes derived from breast cancer cells and patients.","volume":"1","author":"Zhong","year":"2019","journal-title":"Epigenomics"},{"key":"51","doi-asserted-by":"publisher","first-page":"1345","DOI":"10.1039\/c7mb00139h","article-title":"Tumor suppressors microRNA-302d and microRNA-16 inhibit human glioblastoma multiforme by targeting NF-\u03baB and FGF2.","volume":"1","author":"Cui","year":"2017","journal-title":"Mol Biosyst"},{"key":"52","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.cyto.2016.12.013","article-title":"MiR-217 promoted the proliferation and invasion of glioblastoma by repressing YWHAG.","volume":"9","author":"Li","year":"2017","journal-title":"Cytokine"},{"key":"53","doi-asserted-by":"publisher","first-page":"4183","DOI":"10.7150\/thno.21299","article-title":"Identifying and characterizing circRNA-protein interaction.","volume":"7","author":"Yang","year":"2017","journal-title":"Theranostics"},{"key":"54","doi-asserted-by":"publisher","first-page":"3842","DOI":"10.7150\/thno.19764","article-title":"A circular RNA binds to and activates AKT phosphorylation and nuclear localization reducing apoptosis and enhancing cardiac repair.","volume":"7","author":"Sun","year":"2017","journal-title":"Theranostics"},{"key":"55","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s12943-020-01183-9","article-title":"The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer.","volume":"1","author":"Chen","year":"2020","journal-title":"Mol Cancer"},{"key":"56","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.2147\/OTT.S232795","article-title":"Tumor suppressor microRNA-138 suppresses low-grade glioma development and metastasis via regulating IGF2BP2.","volume":"1","author":"Chen","year":"2020","journal-title":"Onco Targets Ther"},{"key":"57","doi-asserted-by":"publisher","first-page":"107641","DOI":"10.1016\/j.celrep.2020.107641","article-title":"Modulation of circRNA metabolism by mA modification.","volume":"3","author":"Bozzoni","year":"2020","journal-title":"Cell Rep"},{"key":"58","doi-asserted-by":"publisher","first-page":"23658","DOI":"10.1002\/jcp.28933","article-title":"LINC01579 promotes cell proliferation by acting as a ceRNA of miR-139-5p to upregulate EIF4G2 expression in glioblastoma.","volume":"23","author":"Xie","year":"2019","journal-title":"J Cell Physiol"},{"key":"59","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1016\/j.celrep.2017.08.027","article-title":"Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs.","volume":"2","author":"Mullen","year":"2017","journal-title":"Cell Rep"},{"key":"60","doi-asserted-by":"publisher","first-page":"4695","DOI":"10.1038\/s41467-019-12651-2","article-title":"N-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis.","volume":"1","author":"Guan","year":"2019","journal-title":"Nat Commun"},{"key":"61","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.omtn.2020.08.004","article-title":"Crosstalk between RNA mA modification and non-coding RNA contributes to cancer growth and progression.","volume":"2","author":"Gao","year":"2020","journal-title":"Mol Ther Nucleic Acids"},{"key":"62","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method.","volume":"2","author":"Schmittgen","year":"2001","journal-title":"Methods"},{"key":"63","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1261\/rna.043687.113","article-title":"circBase: a database for circular RNAs.","volume":"2","author":"Rajewsky","year":"2014","journal-title":"RNA"},{"key":"64","doi-asserted-by":"publisher","first-page":"D149","DOI":"10.1093\/nar\/gkm995","article-title":"The microRNA.org resource: targets and expression.","volume":"3","author":"Sander","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"65","doi-asserted-by":"publisher","first-page":"D925","DOI":"10.1093\/nar\/gkx863","article-title":"CSCD: a database for cancer-specific circular RNAs.","volume":"4","author":"He","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"66","doi-asserted-by":"publisher","first-page":"34985","DOI":"10.1038\/srep34985","article-title":"circRNADb: a comprehensive database for human circular RNAs with protein-coding annotations.","volume":"6","author":"Li","year":"2016","journal-title":"Sci Rep"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T16:07:36Z","timestamp":1617725256000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,11]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,1,31]]}},"alternative-id":["202192","33323543"],"URL":"https:\/\/doi.org\/10.18632\/aging.202192","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,11]]}}}