{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T12:25:03Z","timestamp":1782217503396,"version":"3.54.5"},"reference-count":45,"publisher":"Impact Journals, LLC","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2021,2,28]]},"DOI":"10.18632\/aging.202472","type":"journal-article","created":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T10:23:10Z","timestamp":1613038990000},"page":"5415-5425","source":"Crossref","is-referenced-by-count":23,"title":["A retrospective study of long term follow-up of 2283 vitiligo patients treated by autologous, non-cultured melanocyte\u2013keratinocyte transplantation"],"prefix":"10.18632","volume":"13","author":[{"given":"Dimin","family":"Zhang","sequence":"first","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Wei","sequence":"additional","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weisong","family":"Hong","sequence":"additional","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifang","family":"Fu","sequence":"additional","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guopei","family":"Qian","sequence":"additional","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai-e","family":"Xu","sequence":"additional","affiliation":[{"name":"The Department of Dermatology, The Third People\u2019s Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2021,2,11]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1146\/annurev-immunol-100919-023531","article-title":"Vitiligo: mechanisms of pathogenesis and treatment.","volume":"3","author":"Harris","year":"2020","journal-title":"Annu Rev Immunol"},{"key":"2","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.det.2016.11.013","article-title":"Genetics of vitiligo.","volume":"3","author":"Andersen","year":"2017","journal-title":"Dermatol Clin"},{"key":"3","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1007\/s40257-017-0298-5","article-title":"Vitiligo: an update on pathophysiology and treatment options.","volume":"1","author":"van Geel","year":"2017","journal-title":"Am J Clin Dermatol"},{"key":"4","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jid.2019.03.1142","article-title":"Harnessing the power of regenerative therapy for vitiligo and alopecia areata.","volume":"14","author":"Birlea","year":"2020","journal-title":"J Invest Dermatol"},{"key":"5","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1038\/jid.2011.321","article-title":"Six decades of vitiligo genetics: genome-wide studies provide insights into autoimmune pathogenesis.","volume":"13","author":"Spritz","year":"2012","journal-title":"J Invest Dermatol"},{"key":"6","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1111\/pcmr.12878","article-title":"The enigma and challenges of vitiligo pathophysiology and treatment.","volume":"3","author":"Hamzavi","year":"2020","journal-title":"Pigment Cell Melanoma Res"},{"key":"7","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1111\/jdv.14739","article-title":"The prevalence and odds of depression in patients with vitiligo: a meta-analysis.","volume":"3","author":"Liu","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"8","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1111\/j.1365-2230.2009.03765.x","article-title":"Vitiligo is more than skin deep: a survey of members of the vitiligo society.","volume":"3","author":"Bewley","year":"2010","journal-title":"Clin Exp Dermatol"},{"key":"9","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.jaad.2015.07.039","article-title":"Vitiligo is not a cosmetic disease.","volume":"7","author":"Pandya","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"10","doi-asserted-by":"publisher","first-page":"CD003263","DOI":"10.1002\/14651858.CD003263.pub5","article-title":"Interventions for vitiligo.","author":"Ezzedine","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"11","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1038\/JID.2015.398","article-title":"The vitiligo impact patient scale (VIPs): development and validation of a vitiligo burden assessment tool.","volume":"13","author":"Ezzedine","year":"2016","journal-title":"J Invest Dermatol"},{"key":"12","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1111\/bjd.12532","article-title":"Surgical interventions for vitiligo: an evidence-based review.","volume":"16","author":"Isedeh","year":"2013","journal-title":"Br J Dermatol"},{"key":"13","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.det.2016.11.007","article-title":"Medical and maintenance treatments for vitiligo.","volume":"3","author":"Passeron","year":"2017","journal-title":"Dermatol Clin"},{"key":"14","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.mrfmmm.2004.06.059","article-title":"Mechanisms underlying UV-induced immune suppression.","volume":"57","author":"Ullrich","year":"2005","journal-title":"Mutat Res"},{"key":"15","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1111\/j.0022-202X.2004.23551.x","article-title":"Single UVB overexposure stimulates melanocyte proliferation in murine skin, in contrast to fractionated or UVA-1 exposure.","volume":"12","author":"de Gruijl","year":"2005","journal-title":"J Invest Dermatol"},{"key":"16","first-page":"1","article-title":"Update on the management of vitiligo.","volume":"2","author":"Hamzavi","year":"2019","journal-title":"Skin Therapy Lett"},{"key":"17","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.jaad.2010.10.043","article-title":"Vitiligo: a comprehensive overview part II: treatment options and approach to treatment.","volume":"6","author":"Petronic-Rosic","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"18","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/j.jaad.2011.05.002","article-title":"Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: the experience of an academic medical center in the United States.","volume":"6","author":"Hamzavi","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"19","doi-asserted-by":"publisher","first-page":"521","DOI":"10.2147\/CCID.S151503","article-title":"Autologous non-cultured melanocyte-keratinocyte transplantation in the treatment of vitiligo: patient selection and perspectives.","volume":"1","author":"Esmat","year":"2018","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"20","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1111\/j.1365-2133.2010.10014.x","article-title":"Long-term results of noncultured epidermal cellular grafting in vitiligo, halo naevi, piebaldism and naevus depigmentosus.","volume":"16","author":"Lambert","year":"2010","journal-title":"Br J Dermatol"},{"key":"21","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1046\/j.1365-4362.2003.01628.x","article-title":"Melanocyte-keratinocyte cell transplantation for stable vitiligo.","volume":"4","author":"Mulekar","year":"2003","journal-title":"Int J Dermatol"},{"key":"22","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1001\/archderm.140.10.1211","article-title":"Long-term follow-up study of segmental and focal vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.","volume":"14","author":"Mulekar","year":"2004","journal-title":"Arch Dermatol"},{"key":"23","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1111\/j.1365-4632.2005.02226.x","article-title":"Long-term follow-up study of 142 patients with vitiligo vulgaris treated by autologous, non-cultured melanocyte-keratinocyte cell transplantation.","volume":"4","author":"Mulekar","year":"2005","journal-title":"Int J Dermatol"},{"key":"24","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1001\/archderm.140.10.1203","article-title":"Double-blind placebo-controlled study of autologous transplanted epidermal cell suspensions for repigmenting vitiligo.","volume":"14","author":"Naeyaert","year":"2004","journal-title":"Arch Dermatol"},{"key":"25","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0190-9622(92)70024-a","article-title":"Autologous grafting with noncultured melanocytes: a simplified method for treatment of depigmented lesions.","volume":"2","author":"Surleve-Bazeille","year":"1992","journal-title":"J Am Acad Dermatol"},{"key":"26","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1046\/j.1365-2133.2002.04837.x","article-title":"Long-term follow-up of leucoderma patients treated with transplants of autologous cultured melanocytes, ultrathin epidermal sheets and basal cell layer suspension.","volume":"14","author":"Juhlin","year":"2002","journal-title":"Br J Dermatol"},{"key":"27","first-page":"1032","article-title":"Treatment of vitiligo with a melanocyte-keratinocyte cell suspension versus dermabrasion only: a pilot study with a 12-month follow up.","volume":"1","author":"Ocampo-Candiani","year":"2011","journal-title":"J Drugs Dermatol"},{"key":"28","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/jdv.12426","article-title":"Clinical and treatment characteristics determining therapeutic outcome in patients undergoing autologous non-cultured outer root sheath hair follicle cell suspension for treatment of stable vitiligo.","volume":"2","author":"Saikia","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"29","doi-asserted-by":"publisher","first-page":"393","DOI":"10.4103\/0378-6323.18942","article-title":"A study of autologous melanocyte transfer in treatment of stable vitiligo.","volume":"7","author":"Bilimoria","year":"2005","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"30","doi-asserted-by":"publisher","first-page":"571","DOI":"10.3109\/09546634.2015.1034068","article-title":"Blister roof grafting, cultured melanocytes transplantation and non-cultured epidermal cell suspension transplantation in treating stable vitiligo: a mutual self-control study.","volume":"2","author":"Xu","year":"2015","journal-title":"J Dermatolog Treat"},{"key":"31","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jaad.2017.01.056","article-title":"Long-term follow-up of patients undergoing autologous noncultured melanocyte-keratinocyte transplantation for vitiligo and other leukodermas.","volume":"7","author":"Hamzavi","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"32","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.jaad.2003.12.013","article-title":"Treatment of vitiligo by transplantation of cultured pure melanocyte suspension: analysis of 120 cases.","volume":"5","author":"Hung","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"33","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1111\/j.1365-2133.1995.tb08715.x","article-title":"Transplantation of melanocytes in vitiligo.","volume":"13","author":"Juhlin","year":"1995","journal-title":"Br J Dermatol"},{"key":"34","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1034\/j.1600-0749.2003.00032.x","article-title":"Epidemiology of vitiligo and associated autoimmune diseases in caucasian probands and their families.","volume":"1","author":"Spritz","year":"2003","journal-title":"Pigment Cell Res"},{"key":"35","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.jaad.2015.03.036","article-title":"Autologous cell suspension transplantation using a cell extraction device in segmental vitiligo and piebaldism patients: a randomized controlled pilot study.","volume":"7","author":"Wolkerstorfer","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"36","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.jaad.2016.04.007","article-title":"Twelve-month and sixty-month outcomes of noncultured cellular grafting for vitiligo.","volume":"7","author":"Goh","year":"2016","journal-title":"J Am Acad Dermatol"},{"key":"37","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.1001\/archderm.136.11.1380","article-title":"Treatment of \u201cstable\u201d vitiligo by timedsurgery and transplantation of cultured epidermal autografts.","volume":"13","author":"Pellegrini","year":"2000","journal-title":"Arch Dermatol"},{"key":"38","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1111\/dsu.12444","article-title":"A randomized controlled study of the effects of different modalities of narrow-band ultraviolet B therapy on the outcome of cultured autologous melanocytes transplantation in treating vitiligo.","volume":"4","author":"Xu","year":"2014","journal-title":"Dermatol Surg"},{"key":"39","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1084\/jem.189.4.711","article-title":"312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions.","volume":"18","author":"Krueger","year":"1999","journal-title":"J Exp Med"},{"key":"40","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1097\/DSS.0000000000001190","article-title":"Efficacy of cyclosporine after autologous noncultured melanocyte transplantation in localized stable vitiligo-a pilot, open label, comparative study.","volume":"4","author":"Khoja","year":"2017","journal-title":"Dermatol Surg"},{"key":"41","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1590\/abd1806-4841.20175700","article-title":"Evaluation of treatment response to autologous transplantation of noncultured melanocyte\/keratinocyte cell suspension in patients with stable vitiligo.","volume":"9","author":"Ramos","year":"2017","journal-title":"An Bras Dermatol"},{"key":"42","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1111\/j.1365-2133.2012.10886.x","article-title":"Study of clinical, biochemical and immunological factors determining stability of disease in patients with generalized vitiligo undergoing melanocyte transplantation.","volume":"16","author":"Singh","year":"2012","journal-title":"Br J Dermatol"},{"key":"43","doi-asserted-by":"publisher","first-page":"e60254","DOI":"10.1371\/journal.pone.0060254","article-title":"Dermal mesenchymal stem cells (DMSCs) inhibit skin-homing CD8+ T cell activity, a determining factor of vitiligo patients\u2019 autologous melanocytes transplantation efficiency.","volume":"8","author":"Xu","year":"2013","journal-title":"PLoS One"},{"key":"44","doi-asserted-by":"publisher","first-page":"429","DOI":"10.4103\/0019-5154.119948","article-title":"Role ofreflectance confocal microscopy in determining stability in vitiligo: a preliminary study.","volume":"5","author":"Xu","year":"2013","journal-title":"Indian J Dermatol"},{"key":"45","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1111\/jdv.15411","article-title":"Six-year follow-up of vitiligo patients successfully treated with autologous non-cultured melanocyte-keratinocyte transplantation.","volume":"3","author":"Ezzedine","year":"2019","journal-title":"J Eur Acad Dermatol Venereol"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T16:17:33Z","timestamp":1617725853000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,11]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,2,28]]}},"alternative-id":["202472","33582653"],"URL":"https:\/\/doi.org\/10.18632\/aging.202472","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,11]]}}}