{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:16:55Z","timestamp":1791994615060,"version":"4.4.0"},"reference-count":65,"publisher":"Impact Journals, LLC","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2021,4,15]]},"DOI":"10.18632\/aging.202794","type":"journal-article","created":{"date-parts":[[2021,4,4]],"date-time":"2021-04-04T13:05:06Z","timestamp":1617541506000},"page":"10326-10353","source":"Crossref","is-referenced-by-count":17,"title":["Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving Nrf-2 signaling"],"prefix":"10.18632","volume":"13","author":[{"given":"Qiang","family":"Li","sequence":"first","affiliation":[{"name":"Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing 400067, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qifei","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Linyi People Hospital, Linyi 276000, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Tan","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing 400067, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linfeng","family":"Hu","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400030, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxu","family":"Ge","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400030, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minxuan","family":"Xu","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Medicinal Resources in the Three Gorges Reservoir Region, School of Biological and Chemical Engineering, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Research Center of Brain Intellectual Promotion and Development for Children Aged 0-6 Years, Chongqing University of Education, Chongqing 400067, PR China"},{"name":"Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400030, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2021,4,4]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1681\/ASN.2019101015","article-title":"Fructose production and metabolism in the kidney.","volume":"3","author":"Lanaspa","year":"2020","journal-title":"J Am Soc Nephrol"},{"key":"2","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.freeradbiomed.2019.06.016","article-title":"Antioxidant supplements as a novel mean for blocking recurrent heat stress-induced kidney damage following rehydration with fructose-containing beverages.","volume":"14","author":"S\u00e1nchez-Lozada","year":"2019","journal-title":"Free Radic Biol Med"},{"key":"3","doi-asserted-by":"publisher","first-page":"3521","DOI":"10.2337\/db16-0682","article-title":"Diabetic cardiomyopathy: the case for a role of fructose in disease etiology.","volume":"6","author":"Mellor","year":"2016","journal-title":"Diabetes"},{"key":"4","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s12986-016-0074-1","article-title":"High-fructose and high-fat diet-induced disorders in rats: impact on diabetes risk, hepatic and vascular complications.","volume":"1","author":"Dal","year":"2016","journal-title":"Nutr Metab (Lond)"},{"key":"5","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jep.2016.11.043","article-title":"Aqueous seed extract of Hunteria umbellata (K. Schum.) Hallier f. (Apocynaceae) palliates hyperglycemia, insulin resistance, dyslipidemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome in rats.","volume":"19","author":"Ibitoye","year":"2017","journal-title":"J Ethnopharmacol"},{"key":"6","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1007\/s10620-016-4054-0","article-title":"Role of dietary fructose and hepatic de novo lipogenesis in fatty liver disease.","volume":"6","author":"Kahn","year":"2016","journal-title":"Dig Dis Sci"},{"key":"7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.2131\/jts.43.45","article-title":"High fructose diet feeding accelerates diabetic nephropathy in spontaneously diabetic torii (SDT) rats.","volume":"4","author":"Sugai","year":"2018","journal-title":"J Toxicol Sci"},{"key":"8","doi-asserted-by":"publisher","first-page":"1993","DOI":"10.1007\/s00125-015-3650-4","article-title":"Fructose and uric acid in diabetic nephropathy.","volume":"5","author":"Nakagawa","year":"2015","journal-title":"Diabetologia"},{"key":"9","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s13596-015-0193-7","article-title":"Fructose diet and low dose streptozotocin treatment induces the development of diabetic 0nephropathy in rats.","volume":"1","author":"Gohil","year":"2015","journal-title":"Oriental Pharmacy and Experimental Medicine"},{"key":"10","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.kint.2017.03.004","article-title":"The sweetest thing: blocking fructose metabolism to prevent acute kidney injury?","volume":"9","author":"Reeves","year":"2017","journal-title":"Kidney Int"},{"key":"11","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.freeradbiomed.2015.11.009","article-title":"Dietary (-)-epicatechin mitigates oxidative stress, NO metabolism alterations, and inflammation in renal cortex from fructose-fed rats.","volume":"9","author":"Galleano","year":"2016","journal-title":"Free Radic Biol Med"},{"key":"12","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.freeradbiomed.2015.02.029","article-title":"Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377.","volume":"8","author":"Kong","year":"2015","journal-title":"Free Radic Biol Med"},{"key":"13","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.1016\/j.phymed.2016.08.009","article-title":"Protodioscin ameliorates fructose-induced renal injury via inhibition of the mitogen activated protein kinase pathway.","volume":"2","author":"Guo","year":"2016","journal-title":"Phytomedicine"},{"key":"14","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1681\/ASN.2007091048","article-title":"The role of inflammatory cytokines in diabetic nephropathy.","volume":"1","author":"Mora-Fern\u00e1ndez","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"15","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1093\/ndt\/gfr223","article-title":"Low-fructose diet lowers blood pressure and inflammation in patients with chronic kidney disease.","volume":"2","author":"Manitius","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"16","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jep.2015.04.011","article-title":"Wuling san protects kidney dysfunction by inhibiting renal TLR4\/MyD88 signaling and NLRP3 inflammasome activation in high fructose-induced hyperuricemic mice.","volume":"16","author":"Kong","year":"2015","journal-title":"J Ethnopharmacol"},{"key":"17","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.ejphar.2018.10.008","article-title":"Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-\u03b21\/TGF-\u03b2 type I receptor\/Smads signaling in proximal tubular epithelial cells.","volume":"84","author":"Kong","year":"2019","journal-title":"Eur J Pharmacol"},{"key":"18","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.toxlet.2017.11.031","article-title":"Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.","volume":"28","author":"Peng","year":"2018","journal-title":"Toxicol Lett"},{"key":"19","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1146\/annurev-pharmtox-011112-140320","article-title":"Role of nrf2 in oxidative stress and toxicity.","volume":"5","author":"Ma","year":"2013","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"20","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.jnutbio.2017.01.010","article-title":"Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver.","volume":"4","author":"Mastrocola","year":"2017","journal-title":"J Nutr Biochem"},{"key":"21","doi-asserted-by":"publisher","first-page":"11333","DOI":"10.1021\/j100029a006","article-title":"A study of the fluorescence and reorientation dynamics of carminic acid in primary alcohols.","volume":"9","author":"Blanchard","year":"1995","journal-title":"J Phys Chem"},{"key":"22","doi-asserted-by":"publisher","first-page":"e2","DOI":"10.5415\/apallergy.2019.9.e2","article-title":"Allergy to carminic acid:evidence of involvement of protein-binding hapten.","volume":"9","author":"Ohta","year":"2019","journal-title":"Asia Pac Allergy"},{"key":"23","doi-asserted-by":"publisher","first-page":"5469","DOI":"10.1021\/jo00233a033","article-title":"Simple transformation of carminic acid into kermesic acid.","volume":"5","author":"Scala","year":"1987","journal-title":"J Org Chem"},{"key":"24","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/s0027-5107(02)00212-9","article-title":"Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.","volume":"50","author":"Negishi","year":"2002","journal-title":"Mutat Res"},{"key":"25","first-page":"883","article-title":"Carminic acid: an antioxidant to protect erythrocytes and DNA against radical-induced oxidation.","volume":"2","author":"Wu","year":"2009","journal-title":"J Phys Org Chem"},{"key":"26","first-page":"73","article-title":"Free radical scavenging capacity of carminic acid.","volume":"3","author":"Li","year":"2010","journal-title":"Food Science"},{"key":"27","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1159\/000341485","article-title":"Effect of chenodeoxycholic acid on fibrosis, inflammation and oxidative stress in kidney in high-fructose-fed wistar rats.","volume":"3","author":"Song","year":"2012","journal-title":"Kidney Blood Press Res"},{"key":"28","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1126\/science.1227568","article-title":"JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation.","volume":"33","author":"Davis","year":"2013","journal-title":"Science"},{"key":"29","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3390\/nu9040393","article-title":"Differential effect of sucrose and fructose in combination with a high fat diet on intestinal microbiota and kidney oxidative stress.","volume":"9","author":"Torres","year":"2017","journal-title":"Nutrients"},{"key":"30","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.bbadis.2016.11.005","article-title":"Nrf2 signaling pathway: pivotal roles in inflammation.","volume":"186","author":"Tang","year":"2017","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"31","doi-asserted-by":"publisher","first-page":"F826","DOI":"10.1152\/ajprenal.00444.2019","article-title":"Chronic exercise provides renal-protective effects with upregulation of fatty acid oxidation in the kidney of high fructose-fed rats.","volume":"31","author":"Ito","year":"2020","journal-title":"Am J Physiol Renal Physiol"},{"key":"32","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.lfs.2008.12.014","article-title":"Attenuation of diabetic nephropathy by tocotrienol: involvement of NFkB signaling pathway.","volume":"8","author":"Chopra","year":"2009","journal-title":"Life Sci"},{"key":"33","doi-asserted-by":"publisher","first-page":"48","DOI":"10.4239\/wjd.v1.i2.48","article-title":"Renal function in diabetic nephropathy.","volume":"1","author":"Dabla","year":"2010","journal-title":"World J Diabetes"},{"key":"34","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.cyto.2008.06.015","article-title":"Nephrin and podocin loss is prevented by mycophenolate mofetil in early experimental diabetic nephropathy.","volume":"4","author":"Shen","year":"2008","journal-title":"Cytokine"},{"key":"35","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.freeradbiomed.2018.01.031","article-title":"Deletion of NADPH oxidase 4 reduces severity of traumatic brain injury.","volume":"11","author":"Brann","year":"2018","journal-title":"Free Radic Biol Med"},{"key":"36","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1007\/s40618-019-01134-2","article-title":"L-carnitine counteractsfructose-induced hepatic steatosis through targeting oxidative stress markers.","volume":"4","author":"Terruzzi","year":"2020","journal-title":"J Endocrinol Invest"},{"key":"37","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.cmet.2017.01.004","article-title":"Reducing VEGF-B signaling ameliorates renal lipotoxicity and protects against diabetic kidney disease.","volume":"2","author":"Eriksson","year":"2017","journal-title":"Cell Metab"},{"key":"38","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1001\/jama.2011.861","article-title":"Temporal trends in the prevalence of diabetic kidney disease in the United States.","volume":"30","author":"Himmelfarb","year":"2011","journal-title":"JAMA"},{"key":"39","doi-asserted-by":"publisher","first-page":"117589","DOI":"10.1016\/j.lfs.2020.117589","article-title":"MiR-200b\/c family inhibits renal fibrosis through modulating epithelial-to-mesenchymal transition via targeting fascin-1\/CD44 axis.","volume":"25","author":"Wang","year":"2020","journal-title":"Life Sci"},{"key":"40","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1097\/MPA.0000000000000111","article-title":"Impact of fructose diet and renal failure on the function of pancreatic islets.","volume":"4","author":"Drewa","year":"2014","journal-title":"Pancreas"},{"key":"41","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.cbi.2015.09.002","article-title":"NFAT inhibitor tributylhexadecylphosphoniumbromide, ameliorates high fructose induced insulin resistance and nephropathy.","volume":"24","author":"Tikoo","year":"2015","journal-title":"Chem Biol Interact"},{"key":"42","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.cmet.2010.12.008","article-title":"NF-\u03baB, inflammation, and metabolic disease.","volume":"1","author":"Ghosh","year":"2011","journal-title":"Cell Metab"},{"key":"43","doi-asserted-by":"publisher","first-page":"17023","DOI":"10.1038\/sigtrans.2017.23","article-title":"NF-\u03baB signaling in inflammation.","volume":"2","author":"Sun","year":"2017","journal-title":"Signal Transduct Target Ther"},{"key":"44","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1681\/ASN.2010020218","article-title":"NF-kappaB in renal inflammation.","volume":"2","author":"Ortiz","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"45","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.freeradbiomed.2019.05.031","article-title":"Endoplasmic reticulum stress-induced iRhom2 up-regulation promotes macrophage-regulated cardiac inflammation and lipid deposition in high fat diet (HFD)-challenged mice: intervention of fisetin and metformin.","volume":"14","author":"Tan","year":"2019","journal-title":"Free Radic Biol Med"},{"key":"46","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.ejphar.2011.06.011","article-title":"Genistein modulates NF-\u03baB-associated renal inflammation, fibrosis and podocyte abnormalities in fructose-fed rats.","volume":"66","author":"Anuradha","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"47","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1159\/000331058","article-title":"Evaluation of JNK blockade as an early intervention treatment for type 1 diabetic nephropathy in hypertensive rats.","volume":"3","author":"Tesch","year":"2011","journal-title":"Am J Nephrol"},{"key":"48","doi-asserted-by":"publisher","first-page":"83","DOI":"10.2174\/157016306776637555","article-title":"Advanced glycation end products (AGEs) and their receptor (RAGE) system in diabetic retinopathy.","volume":"3","author":"Matsui","year":"2006","journal-title":"Curr Drug Discov Technol"},{"key":"49","doi-asserted-by":"publisher","first-page":"4826724","DOI":"10.1155\/2017\/4826724","article-title":"The Nrf2\/Keap1\/ARE pathway and oxidative stress as a therapeutic target in type II diabetes mellitus.","volume":"201","author":"Ceradini","year":"2017","journal-title":"J Diabetes Res"},{"key":"50","doi-asserted-by":"publisher","first-page":"5126","DOI":"10.1038\/s41598-018-22913-6","article-title":"Association of NF-E2 related factor 2 (Nrf2) and inflammatory cytokines in recent onset type 2 diabetes mellitus.","volume":"8","author":"Ramkumar","year":"2018","journal-title":"Sci Rep"},{"key":"51","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.fct.2017.09.050","article-title":"Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2\/NF-\u03baB transcriptional pathway.","volume":"10","author":"Liu","year":"2017","journal-title":"Food Chem Toxicol"},{"key":"52","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.freeradbiomed.2018.12.034","article-title":"Loss of RIP3 initiates annihilation of high-fat diet initialized nonalcoholic hepatosteatosis: a mechanism involving toll-like receptor 4 and oxidative stress.","volume":"13","author":"Mingxing","year":"2019","journal-title":"Free Radic Biol Med"},{"key":"53","doi-asserted-by":"publisher","first-page":"6293","DOI":"10.1007\/s12035-019-1512-7","article-title":"Hesperetin confers neuroprotection by regulating Nrf2\/TLR4\/NF-\u03baB signaling in an A\u03b2 mouse model.","volume":"5","author":"Kim","year":"2019","journal-title":"Mol Neurobiol"},{"key":"54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.celrep.2017.09.026","article-title":"AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species.","volume":"2","author":"Jones","year":"2017","journal-title":"Cell Rep"},{"key":"55","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s12943-017-0648-1","article-title":"ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.","volume":"1","author":"Shi","year":"2017","journal-title":"Mol Cancer"},{"key":"56","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1111\/j.1365-2249.2009.03924.x","article-title":"Activation of AMPK inhibits inflammation in MRL\/lpr mouse mesangial cells.","volume":"15","author":"Reilly","year":"2009","journal-title":"Clin Exp Immunol"},{"key":"57","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1096\/fj.04-3144fje","article-title":"Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle.","volume":"1","author":"Pilegaard","year":"2005","journal-title":"FASEB J"},{"key":"58","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.cell.2008.06.051","article-title":"AMPK and PPARdelta agonists are exercise mimetics.","volume":"13","author":"Evans","year":"2008","journal-title":"Cell"},{"key":"59","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1172\/JCI16567","article-title":"The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity.","volume":"11","author":"Wojtaszewski","year":"2003","journal-title":"J Clin Invest"},{"key":"60","doi-asserted-by":"publisher","first-page":"12032","DOI":"10.18632\/aging.102534","article-title":"Compound 13 activates AMPK-Nrf2 signaling to protect neuronal cells from oxygen glucose deprivation-reoxygenation.","volume":"1","author":"Han","year":"2019","journal-title":"Aging (Albany NY)"},{"key":"61","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.taap.2019.03.007","article-title":"4-O-methylhonokiol ameliorates type 2 diabetes-induced nephropathy in mice likely by activation of AMPK-mediated fatty acid oxidation and Nrf2-mediated anti-oxidative stress.","volume":"37","author":"Bi","year":"2019","journal-title":"Toxicol Appl Pharmacol"},{"key":"62","doi-asserted-by":"publisher","first-page":"e1800427","DOI":"10.1002\/adhm.201800427","article-title":"Multicombination approach suppresses listeria monocytogenes-induced septicemia-associated acute hepatic failure: the role of iRhom2 signaling.","volume":"7","author":"Tan","year":"2018","journal-title":"Adv Healthc Mater"},{"key":"63","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.molmet.2019.08.020","article-title":"Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice.","volume":"2","author":"Feng","year":"2019","journal-title":"Mol Metab"},{"key":"64","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1002\/mnfr.201500547","article-title":"Stachyose increases absorption and hepatoprotective effect of tea polyphenols in high fructose-fed mice.","volume":"6","author":"Yang","year":"2016","journal-title":"Mol Nutr Food Res"},{"key":"65","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.peptides.2013.02.002","article-title":"Effect of PACAP treatment on kidney morphology and cytokine expression in rat diabetic nephropathy.","volume":"4","author":"Reglodi","year":"2013","journal-title":"Peptides"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T16:56:16Z","timestamp":1620320176000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.202794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,4]]},"references-count":65,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,4,15]]}},"alternative-id":["202794","33819919"],"URL":"https:\/\/doi.org\/10.18632\/aging.202794","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,4]]}}}