{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:05:47Z","timestamp":1760123147582},"reference-count":54,"publisher":"Impact Journals, LLC","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2021,11,30]]},"DOI":"10.18632\/aging.203712","type":"journal-article","created":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T00:50:45Z","timestamp":1638060645000},"page":"24740-24752","source":"Crossref","is-referenced-by-count":5,"title":["Inhibition of Fam114A1 protects melanocytes from apoptosis through higher RACK1 expression"],"prefix":"10.18632","volume":"13","author":[{"given":"Miaoni","family":"Zhou","sequence":"first","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuquan","family":"Lin","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingang","family":"Wu","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuyi","family":"Ping","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Xu","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Jin","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aie","family":"Xu","sequence":"additional","affiliation":[{"name":"The Third People\u2019s Hospital of Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2021,11,27]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1111\/j.1471-4159.2006.04093.x","article-title":"Noxp20 and Noxp70, two new markers of early neuronal differentiation, detected in teratocarcinoma-derived neuroectodermic precursor cells.","volume":"9","author":"Kellermann","year":"2006","journal-title":"J Neurochem"},{"key":"2","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.jprot.2016.05.003","article-title":"Proteomic profiling reveals dopaminergic regulation of progenitor cell functions of goldfish radial glial cells","volume":"14","author":"Trudeau","year":"2016","journal-title":"J Proteomics"},{"key":"3","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1016\/j.bbrc.2015.11.055","article-title":"Characterization and sub-cellular localization of GalNAc-binding proteins isolated from human hepatic stellate cells.","volume":"46","author":"Li","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"4","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/nmeth.2368","article-title":"Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells.","volume":"1","author":"Cravatt","year":"2013","journal-title":"Nat Methods"},{"key":"5","doi-asserted-by":"publisher","first-page":"16008","DOI":"10.1038\/npjgenmed.2016.8","article-title":"Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease.","volume":"1","author":"Brown","year":"2016","journal-title":"NPJ Genom Med"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/7651_2015_305","volume-title":"Methods Mol Biol","author":"Sommer","year":"2015"},{"key":"7","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1002\/stem.740","article-title":"Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor.","volume":"2","author":"Herlyn","year":"2011","journal-title":"Stem Cells"},{"key":"8","doi-asserted-by":"publisher","first-page":"3179","DOI":"10.1096\/fj.08-123596","article-title":"Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells.","volume":"2","author":"Bennett","year":"2009","journal-title":"FASEB J"},{"key":"9","volume-title":"StatPearls","author":"Lui","year":"2021"},{"key":"10","doi-asserted-by":"publisher","first-page":"284","DOI":"10.5966\/sctm.2012-0147","article-title":"Concise review: adult mesenchymal stem cells, adult neural crest stem cells, and therapy of neurological pathologies: a state of play.","volume":"2","author":"Wislet-Gendebien","year":"2013","journal-title":"Stem Cells Transl Med"},{"key":"11","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.det.2018.02.007","article-title":"End-Stage Renal Disease Chronic Itch and Its Management.","volume":"3","author":"Szepietowski","year":"2018","journal-title":"Dermatol Clin"},{"key":"12","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1177\/120347541201600404","article-title":"Potential role of neurogenic inflammatory factors in the pathogenesis of vitiligo.","volume":"1","author":"Zhou","year":"2012","journal-title":"J Cutan Med Surg"},{"key":"13","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1159\/000067818","article-title":"New aspects in acne inflammation.","volume":"20","author":"Morohashi","year":"2003","journal-title":"Dermatology"},{"key":"14","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.jdcr.2019.01.021","article-title":"A novel KIT mutation in a family with expanded syndrome of piebaldism.","volume":"5","author":"Wakil","year":"2019","journal-title":"JAAD Case Rep"},{"key":"15","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1111\/ced.13833","article-title":"Atypical presentation of dyschromatosis universalis hereditaria with a novel ABCB6 mutation.","volume":"4","author":"Lin","year":"2019","journal-title":"Clin Exp Dermatol"},{"key":"16","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1073\/pnas.91.3.839","article-title":"Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.","volume":"9","author":"Mochly-Rosen","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"17","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1002\/hep.25978","article-title":"Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity.","volume":"5","author":"Zhang","year":"2013","journal-title":"Hepatology"},{"key":"18","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1038\/embor.2010.169","article-title":"Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrest.","volume":"1","author":"Inada","year":"2010","journal-title":"EMBO Rep"},{"key":"19","doi-asserted-by":"publisher","first-page":"11047","DOI":"10.1158\/0008-5472.CAN-06-0596","article-title":"Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.","volume":"6","author":"Weber","year":"2006","journal-title":"Cancer Res"},{"key":"20","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1016\/j.cell.2014.10.041","article-title":"RACK1 controls IRES-mediated translation of viruses.","volume":"15","author":"Imler","year":"2014","journal-title":"Cell"},{"key":"21","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1261\/rna.061671.117","article-title":"ASC1 and RPS3: new actors in 18S nonfunctional rRNA decay.","volume":"2","author":"Moore","year":"2017","journal-title":"RNA"},{"key":"22","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1261\/rna.049080.114","article-title":"Asc1, homolog of human RACK1, prevents frameshifting in yeast by ribosomes stalled at CGA codon repeats.","volume":"2","author":"Grayhack","year":"2015","journal-title":"RNA"},{"key":"23","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1038\/onc.2014.127","article-title":"RACK1, a versatile hub in cancer.","volume":"3","author":"Xie","year":"2015","journal-title":"Oncogene"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15218","article-title":"Ribosomes as a nexus between translation and cancer progression: Focus on ribosomal Receptor for Activated C Kinase 1 (RACK1) in breast cancer.","author":"Racchi","year":"2020","journal-title":"Br J Pharmacol"},{"key":"25","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.cellsig.2017.01.013","article-title":"The cyclic AMP phosphodiesterase 4D5 (PDE4D5)\/receptor for activated C-kinase 1 (RACK1) signalling complex as a sensor of the extracellular nano-environment.","volume":"3","author":"Bird","year":"2017","journal-title":"Cell Signal"},{"key":"26","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/j.autrev.2010.02.013","article-title":"Current remedies for vitiligo.","volume":"9","author":"Ali","year":"2010","journal-title":"Autoimmun Rev"},{"key":"27","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.autrev.2006.03.012","article-title":"Therapeutic implications of autoimmune vitiligo T cells.","volume":"5","author":"Le Poole","year":"2006","journal-title":"Autoimmun Rev"},{"key":"28","doi-asserted-by":"publisher","first-page":"e60254","DOI":"10.1371\/journal.pone.0060254","article-title":"Dermal mesenchymal stem cells (DMSCs) inhibit skin-homing CD8+ T cell activity, a determining factor of vitiligo patients\u2019 autologous melanocytes transplantation efficiency.","volume":"8","author":"Xu","year":"2013","journal-title":"PLoS One"},{"key":"29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.3892\/mmr.2012.1117","article-title":"CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis.","volume":"7","author":"Xu","year":"2013","journal-title":"Mol Med Rep"},{"key":"30","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1111\/j.1365-2133.2011.10398.x","article-title":"Ratio of size of recipient and donor areas in treatment of vitiligo by autologous cultured melanocyte transplantation.","volume":"16","author":"Xu","year":"2011","journal-title":"Br J Dermatol"},{"key":"31","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1111\/j.1468-3083.2010.03824.x","article-title":"Treatment of vitiligo in children and adolescents by autologous cultured pure melanocytes transplantation with comparison of efficacy to results in adults.","volume":"2","author":"Xu","year":"2011","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"32","doi-asserted-by":"publisher","first-page":"e93232","DOI":"10.1371\/journal.pone.0093232","article-title":"Interferon-\u03b3 induces senescence in normal human melanocytes.","volume":"9","author":"Xu","year":"2014","journal-title":"PLoS One"},{"key":"33","doi-asserted-by":"publisher","first-page":"5415","DOI":"10.18632\/aging.202472","article-title":"A retrospective study of long term follow-up of 2283 vitiligo patients treated by autologous, non-cultured melanocyte-keratinocyte transplantation.","volume":"1","author":"Xu","year":"2021","journal-title":"Aging (Albany NY)"},{"key":"34","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/j.1600-0625.2009.01053.x","article-title":"\u201cTranscription physiology\u201d of pigment formation in melanocytes: central role of MITF.","volume":"1","author":"Borovansk\u00fd","year":"2010","journal-title":"Exp Dermatol"},{"key":"35","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.molmed.2006.07.008","article-title":"MITF: master regulator of melanocyte development and melanoma oncogene.","volume":"1","author":"Fisher","year":"2006","journal-title":"Trends Mol Med"},{"key":"36","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ijbiomac.2015.07.064","article-title":"Inhibitory effect of brazilein on tyrosinase and melanin synthesis: Kinetics and in silico approach.","volume":"8","author":"Siva","year":"2015","journal-title":"Int J Biol Macromol"},{"key":"37","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1248\/bpb.31.154","article-title":"Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis.","volume":"3","author":"Choi","year":"2008","journal-title":"Biol Pharm Bull"},{"key":"38","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/1478-811X-9-22","article-title":"RACK1, A multifaceted scaffolding protein: Structure and function.","volume":"9","author":"Kiely","year":"2011","journal-title":"Cell Commun Signal"},{"key":"39","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1111\/pcmr.12878","article-title":"The enigma and challenges of vitiligo pathophysiology and treatment.","volume":"3","author":"Hamzavi","year":"2020","journal-title":"Pigment Cell Melanoma Res"},{"key":"40","doi-asserted-by":"publisher","first-page":"100981","DOI":"10.1016\/j.arr.2019.100981","article-title":"Premature cell senescence in human skin: Dual face in chronic acquired pigmentary disorders.","volume":"5","author":"Picardo","year":"2020","journal-title":"Ageing Res Rev"},{"key":"41","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1001\/jama.293.6.730","article-title":"New insights and new therapies in vitiligo.","volume":"29","author":"Grimes","year":"2005","journal-title":"JAMA"},{"key":"42","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1034\/j.1600-0749.2003.00023.x","article-title":"Evidence for an autoimmune pathogenesis of vitiligo.","volume":"1","author":"Naeyaert","year":"2003","journal-title":"Pigment Cell Res"},{"key":"43","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1001\/jamadermatol.2019.0696","article-title":"Treatment Outcomes of Topical Calcineurin Inhibitor Therapy for Patients With Vitiligo: A Systematic Review and Meta-analysis.","volume":"15","author":"Bae","year":"2019","journal-title":"JAMA Dermatol"},{"key":"44","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1111\/j.1525-1470.2009.00978.x","article-title":"Childhood vitiligo: a long-term study of localized vitiligo treated by noncultured cellular grafting.","volume":"2","author":"Al Saeed","year":"2010","journal-title":"Pediatr Dermatol"},{"key":"45","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1038\/jid.2009.32","article-title":"Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients.","volume":"12","author":"Luiten","year":"2009","journal-title":"J Invest Dermatol"},{"key":"46","doi-asserted-by":"publisher","first-page":"e1022","DOI":"10.1038\/cddis.2013.539","article-title":"Stress-induced RNASET2 overexpression mediates melanocyte apoptosis via the TRAF2 pathway","volume":"5","author":"Xiang","year":"2014","journal-title":"Cell Death Dis"},{"key":"47","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.3892\/or.2015.3920","article-title":"RACK1 modulates apoptosis induced by sorafenib in HCC cells by interfering with the IRE1\/XBP1 axis.","volume":"3","author":"Chen","year":"2015","journal-title":"Oncol Rep"},{"key":"48","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1177\/1947601913486348","article-title":"RACK1 Function in Cell Motility and Protein Synthesis.","volume":"4","author":"Ronai","year":"2013","journal-title":"Genes Cancer"},{"key":"49","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1053\/j.gastro.2011.12.046","article-title":"RACK1 suppresses gastric tumorigenesis by stabilizing the \u03b2-catenin destruction complex.","volume":"14","author":"Li","year":"2012","journal-title":"Gastroenterology"},{"key":"50","doi-asserted-by":"publisher","first-page":"2667","DOI":"10.1016\/j.yexcr.2007.05.013","article-title":"RACK1 regulates Src activity and modulates paxillin dynamics during cell migration.","volume":"31","author":"Huttenlocher","year":"2007","journal-title":"Exp Cell Res"},{"key":"51","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1021\/pr9009386","article-title":"Identification of Rack1, EF-Tu and Rhodanese as aging-related proteins in human colonic epithelium by proteomic analysis.","volume":"9","author":"Xiao","year":"2010","journal-title":"J Proteome Res"},{"key":"52","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1016\/j.bbrc.2014.03.114","article-title":"Acute dyskerin depletion triggers cellular senescence and renders osteosarcoma cells resistant to genotoxic stress-induced apoptosis.","volume":"44","author":"Alawi","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"key":"53","doi-asserted-by":"publisher","first-page":"e727","DOI":"10.1038\/cddis.2013.199","article-title":"Mitochondrial DNA damage induces apoptosis in senescent cells.","volume":"4","author":"Rodier","year":"2013","journal-title":"Cell Death Dis"},{"key":"54","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s10495-009-0316-z","article-title":"Hallmarks for senescence in carcinogenesis: novel signaling players.","volume":"1","author":"Kazanietz","year":"2009","journal-title":"Apoptosis"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.203712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T20:06:55Z","timestamp":1638821215000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.203712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,27]]},"references-count":54,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2021,11,30]]}},"alternative-id":["203712","34837888"],"URL":"https:\/\/doi.org\/10.18632\/aging.203712","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,27]]}}}