{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T15:37:37Z","timestamp":1774366657356,"version":"3.50.1"},"reference-count":79,"publisher":"Impact Journals, LLC","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2023,11,30]]},"DOI":"10.18632\/aging.205200","type":"journal-article","created":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T16:05:47Z","timestamp":1699632347000},"page":"12852-12872","source":"Crossref","is-referenced-by-count":3,"title":["Peptidome analysis reveals critical roles for peptides in a rat model of intestinal ischemia\/reperfusion injury"],"prefix":"10.18632","volume":"15","author":[{"given":"Jiaxuan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Trauma Center, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Clinical Biobank and Institute of Oncology, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Clinical Biobank and Institute of Oncology, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannan","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leijun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhua","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Trauma Center, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofei","family":"Zhi","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"750731","DOI":"10.3389\/fmed.2021.750731","article-title":"Oxidative Stress in Intestinal Ischemia-Reperfusion.","volume":"8","author":"Fan","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"2","doi-asserted-by":"publisher","first-page":"17788","DOI":"10.1038\/s41598-018-36198-2","article-title":"DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.","volume":"8","author":"Ding","year":"2018","journal-title":"Sci Rep"},{"key":"3","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1097\/MOT.0b013e32835ef1eb","article-title":"New insights in intestinal ischemia-reperfusion injury: implications for intestinal transplantation.","volume":"1","author":"Olde Damink","year":"2013","journal-title":"Curr Opin Organ Transplant"},{"key":"4","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3892\/etm.2021.10369","article-title":"MicroRNA-146a overexpression alleviates intestinal ischemia\/reperfusion-induced acute lung injury in mice.","volume":"2","author":"Li","year":"2021","journal-title":"Exp Ther Med"},{"key":"5","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.3892\/ijmm.2018.3480","article-title":"The interplay of BMP4 and IL-7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemi\u2c65reperfusion.","volume":"4","author":"Zhang","year":"2018","journal-title":"Int J Mol Med"},{"key":"6","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1038\/s41419-018-0436-x","article-title":"The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2\/ARE signaling pathway.","volume":"9","author":"Li","year":"2018","journal-title":"Cell Death Dis"},{"key":"7","doi-asserted-by":"publisher","first-page":"4359305","DOI":"10.1155\/2020\/4359305","article-title":"Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia\/Reperfusion Injury in Rats through NF-\u03baB\/NLRP3 Pathway.","volume":"202","author":"Zhou","year":"2020","journal-title":"Mediators Inflamm"},{"key":"8","doi-asserted-by":"publisher","first-page":"7857082","DOI":"10.1155\/2019\/7857082","article-title":"Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia\/Reperfusion.","volume":"201","author":"Zhou","year":"2019","journal-title":"Oxid Med Cell Longev"},{"key":"9","doi-asserted-by":"publisher","first-page":"116737","DOI":"10.1016\/j.lfs.2019.116737","article-title":"Peptidomics analysis of umbilical cord blood reveals potential preclinical biomarkers for neonatal respiratory distress syndrome.","volume":"23","author":"Han","year":"2019","journal-title":"Life Sci"},{"key":"10","doi-asserted-by":"publisher","first-page":"9061568","DOI":"10.1155\/2020\/9061568","article-title":"The Platelet microRNA Profile of Kawasaki Disease: Identification of Novel Diagnostic Biomarkers.","volume":"202","author":"Huang","year":"2020","journal-title":"Biomed Res Int"},{"key":"11","doi-asserted-by":"publisher","first-page":"7337","DOI":"10.3892\/mmr.2017.7582","article-title":"Peptidome analysis of amniotic fluid from pregnancies with preeclampsia.","volume":"1","author":"Jia","year":"2017","journal-title":"Mol Med Rep"},{"key":"12","doi-asserted-by":"publisher","first-page":"7267","DOI":"10.1021\/ac0607010","article-title":"Profiling signaling peptides in single mammalian cells using mass spectrometry.","volume":"7","author":"Sweedler","year":"2006","journal-title":"Anal Chem"},{"key":"13","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/nchembio.1120","article-title":"Peptidomic discovery of short open reading frame-encoded peptides in human cells.","volume":"9","author":"Saghatelian","year":"2013","journal-title":"Nat Chem Biol"},{"key":"14","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1053\/gast.2001.22158","article-title":"Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.","volume":"12","author":"Kasuga","year":"2001","journal-title":"Gastroenterology"},{"key":"15","doi-asserted-by":"publisher","first-page":"741","DOI":"10.3389\/fendo.2019.00741","article-title":"A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived FromMice.","volume":"1","author":"Zeng","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"key":"16","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1038\/cmi.2015.36","article-title":"Effect of ebosin on modulating interleukin-1\u03b2-induced inflammatory responses in rat fibroblast-like synoviocytes.","volume":"1","author":"Li","year":"2016","journal-title":"Cell Mol Immunol"},{"key":"17","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s00383-002-0834-z","article-title":"Morphologic changes and lipid peroxidation in renal tissues of young rats following intestinal ischemia-reperfusion.","volume":"1","author":"Bulut","year":"2002","journal-title":"Pediatr Surg Int"},{"key":"18","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.nut.2009.04.010","article-title":"Endotoxin level in ischemia-reperfusion injury in rats: effect of glutamine pretreatment on endotoxin levels and gut morphology.","volume":"2","author":"Melli","year":"2010","journal-title":"Nutrition"},{"key":"19","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.febslet.2014.01.022","article-title":"MiR-874 promotes intestinal barrier dysfunction through targeting AQP3 following intestinal ischemic injury.","volume":"58","author":"Xu","year":"2014","journal-title":"FEBS Lett"},{"key":"20","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.3892\/ijmm.2017.3341","article-title":"Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.","volume":"4","author":"Yang","year":"2018","journal-title":"Int J Mol Med"},{"key":"21","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1001\/archsurg.1970.01340280030009","article-title":"Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal.","volume":"10","author":"Gurd","year":"1970","journal-title":"Arch Surg"},{"key":"22","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1111\/cas.14881","article-title":"Proteomic analysis of urinary and tissue-exudative extracellular vesicles to discover novel bladder cancer biomarkers.","volume":"11","author":"Kato","year":"2021","journal-title":"Cancer Sci"},{"key":"23","doi-asserted-by":"publisher","first-page":"5390","DOI":"10.3390\/ijms21155390","article-title":"Expression of Nectin-4 and PD-L1 in Upper Tract Urothelial Carcinoma.","volume":"2","author":"Fushimi","year":"2020","journal-title":"Int J Mol Sci"},{"key":"24","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1038\/nprot.2012.024","article-title":"A positive\/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue.","volume":"7","author":"Asara","year":"2012","journal-title":"Nat Protoc"},{"key":"25","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.canlet.2020.05.009","article-title":"LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers.","volume":"48","author":"Tang","year":"2020","journal-title":"Cancer Lett"},{"key":"26","doi-asserted-by":"publisher","first-page":"3113","DOI":"10.1016\/j.febslet.2011.08.045","article-title":"Knockdown of aquaporin 3 is involved in intestinal barrier integrity impairment.","volume":"58","author":"Xu","year":"2011","journal-title":"FEBS Lett"},{"key":"27","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/s41419-018-0450-z","article-title":"miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia\/reperfusion injury by targeting nurr1.","volume":"9","author":"Tian","year":"2018","journal-title":"Cell Death Dis"},{"key":"28","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.2147\/DDDT.S91321","article-title":"SPOCK1 promotes tumor growth and metastasis in human prostate cancer.","volume":"1","author":"Wang","year":"2016","journal-title":"Drug Des Devel Ther"},{"key":"29","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.ecoenv.2019.03.015","article-title":"Peptidomic analysis of zebrafish embryos exposed to polychlorinated biphenyls and their impact on eye development.","volume":"17","author":"Tong","year":"2019","journal-title":"Ecotoxicol Environ Saf"},{"key":"30","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.clim.2014.04.018","article-title":"Membrane lipid interactions in intestinal ischemia\/reperfusion-induced Injury.","volume":"15","author":"Fleming","year":"2014","journal-title":"Clin Immunol"},{"key":"31","doi-asserted-by":"publisher","first-page":"7873","DOI":"10.1111\/jcmm.15420","article-title":"miRNA-182\/Deptor\/mTOR axis regulates autophagy to reduce intestinal ischaemia\/reperfusion injury.","volume":"2","author":"Duan","year":"2020","journal-title":"J Cell Mol Med"},{"key":"32","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.3906\/sag-2008-258","article-title":"The role of anakinra in the modulation of intestinal cell apoptosis and inflammatory response during ischemia\/reperfusion.","volume":"5","author":"Erkasap","year":"2021","journal-title":"Turk J Med Sci"},{"key":"33","doi-asserted-by":"publisher","first-page":"191624","DOI":"10.1155\/2014\/191624","article-title":"The protective effects of curcumin on experimental acute liver lesion induced by intestinal ischemia-reperfusion through inhibiting the pathway of NF-\u03baB in a rat model.","volume":"201","author":"Tian","year":"2014","journal-title":"Oxid Med Cell Longev"},{"key":"34","doi-asserted-by":"publisher","first-page":"6120194","DOI":"10.1155\/2020\/6120194","article-title":"Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia\/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase\/Akt Pathway.","volume":"202","author":"He","year":"2020","journal-title":"Oxid Med Cell Longev"},{"key":"35","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1620\/tjem.216.197","article-title":"Mesenteric ischemia: still a deadly puzzle for the medical community.","volume":"21","author":"Safioleas","year":"2008","journal-title":"Tohoku J Exp Med"},{"key":"36","doi-asserted-by":"publisher","first-page":"G63","DOI":"10.1152\/ajpgi.00112.2013","article-title":"Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research.","volume":"30","author":"Blikslager","year":"2015","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"37","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s00109-016-1464-6","article-title":"Nurr1 promotes intestinal regeneration after ischemia\/reperfusion injury by inhibiting the expression of p21 (Waf1\/Cip1).","volume":"9","author":"Tian","year":"2017","journal-title":"J Mol Med (Berl)"},{"key":"38","doi-asserted-by":"publisher","first-page":"BSR20191043","DOI":"10.1042\/BSR20191043","article-title":"MicroRNA files in the prevention of intestinal ischemia\/reperfusion injury by hydrogen rich saline.","volume":"4","author":"Huang","year":"2020","journal-title":"Biosci Rep"},{"key":"39","doi-asserted-by":"publisher","first-page":"4463","DOI":"10.1002\/pmic.201000078","article-title":"Proteomic analysis of intestinal ischemia\/reperfusion injury and ischemic preconditioning in rats reveals the protective role of aldose reductase.","volume":"1","author":"Huang","year":"2010","journal-title":"Proteomics"},{"key":"40","doi-asserted-by":"publisher","first-page":"7101","DOI":"10.1002\/jcp.26633","article-title":"Peptidome analysis of lung tissues from a hyperoxia-induced bronchopulmonary dysplasia mouse model: Insights into the pathophysiological process of bronchopulmonary dysplasia.","volume":"23","author":"Han","year":"2018","journal-title":"J Cell Physiol"},{"key":"41","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1159\/000456282","article-title":"Peptidomic Analysis of Cultured Cardiomyocytes Exposed to Acute Ischemic-Hypoxia.","volume":"4","author":"Song","year":"2017","journal-title":"Cell Physiol Biochem"},{"key":"42","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.drudis.2014.10.003","article-title":"Peptide therapeutics: current status and future directions.","volume":"2","author":"Hoffmann","year":"2015","journal-title":"Drug Discov Today"},{"key":"43","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.drudis.2013.05.011","article-title":"Future directions for peptide therapeutics development.","volume":"1","author":"Reichert","year":"2013","journal-title":"Drug Discov Today"},{"key":"44","doi-asserted-by":"publisher","first-page":"1890","DOI":"10.1002\/jcb.29424","article-title":"Peptidomics analysis of myometrium tissues in term labor compared with term nonlabor.","volume":"12","author":"Li","year":"2020","journal-title":"J Cell Biochem"},{"key":"45","doi-asserted-by":"publisher","first-page":"3306","DOI":"10.3390\/ijms23063306","article-title":"Peptidomic Analysis on Mouse Lung Tissue Reveals AGDP as a Potential Bioactive Peptide against Pseudorabies Virus Infection.","volume":"2","author":"Yang","year":"2022","journal-title":"Int J Mol Sci"},{"key":"46","doi-asserted-by":"publisher","first-page":"7696","DOI":"10.3390\/ijms21207696","article-title":"The Human Digestive Tract Is Capable of Degrading Gluten from Birth.","volume":"2","author":"Rodr\u00edguez-Aparicio","year":"2020","journal-title":"Int J Mol Sci"},{"key":"47","doi-asserted-by":"publisher","first-page":"2662","DOI":"10.3382\/ps\/pev260","article-title":"Effects of exogenous proteases without or with carbohydrases on nutrient digestibility and disappearance of non-starch polysaccharides in broiler chickens.","volume":"9","author":"Romero","year":"2015","journal-title":"Poult Sci"},{"key":"48","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1586\/14789450.2013.841547","article-title":"Proteomic identification of protease cleavage sites: cell-biological and biomedical applications.","volume":"1","author":"Schilling","year":"2013","journal-title":"Expert Rev Proteomics"},{"key":"49","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/s41368-018-0032-z","article-title":"Salivary protease spectrum biomarkers of oral cancer.","volume":"1","author":"Jiang","year":"2019","journal-title":"Int J Oral Sci"},{"key":"50","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/978-1-4939-6850-3_14","article-title":"Profiling of Protease Cleavage Sites by Proteome-Derived Peptide Libraries and Quantitative Proteomics.","volume":"157","author":"Schilling","year":"2017","journal-title":"Methods Mol Biol"},{"key":"51","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1007\/s00018-009-0007-5","article-title":"Processing of peptide and hormone precursors at the dibasic cleavage sites.","volume":"6","author":"Fahy","year":"2009","journal-title":"Cell Mol Life Sci"},{"key":"52","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1038\/s41598-019-57095-2","article-title":"Oxidised Metof human serum albumin is a biomarker of oxidative stress, reflecting glycaemic fluctuations and hypoglycaemia in diabetes.","volume":"1","author":"Shichiri","year":"2020","journal-title":"Sci Rep"},{"key":"53","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1089\/152308603770310239","article-title":"Oxidation of methionine residues of proteins: biological consequences.","volume":"5","author":"Levine","year":"2003","journal-title":"Antioxid Redox Signal"},{"key":"54","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s12276-018-0098-x","article-title":"NAA10-related syndrome.","volume":"5","author":"Lyon","year":"2018","journal-title":"Exp Mol Med"},{"key":"55","doi-asserted-by":"publisher","first-page":"e1700475","DOI":"10.1126\/sciadv.1700475","article-title":"Membrane localization of acetylated CNK1 mediates a positive feedback on RAF\/ERK signaling.","volume":"3","author":"Radziwill","year":"2017","journal-title":"Sci Adv"},{"key":"56","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1038\/s41580-018-0081-3","article-title":"Functions and mechanisms of non-histone protein acetylation.","volume":"2","author":"Choudhary","year":"2019","journal-title":"Nat Rev Mol Cell Biol"},{"key":"57","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1042\/BJ20041071","article-title":"Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.","volume":"38","author":"Lillehaug","year":"2005","journal-title":"Biochem J"},{"key":"58","doi-asserted-by":"publisher","first-page":"109937","DOI":"10.1016\/j.celrep.2021.109937","article-title":"Function and molecular mechanism of N-terminal acetylation in autophagy.","volume":"3","author":"Lu","year":"2021","journal-title":"Cell Rep"},{"key":"59","doi-asserted-by":"publisher","first-page":"7182428","DOI":"10.1155\/2020\/7182428","article-title":"Peptidomics Analysis Reveals Peptide PDCryab1 Inhibits Doxorubicin-Induced Cardiotoxicity.","volume":"202","author":"Qian","year":"2020","journal-title":"Oxid Med Cell Longev"},{"key":"60","doi-asserted-by":"publisher","first-page":"14090","DOI":"10.1002\/jcp.28098","article-title":"Peptidome analysis reveals the involvement of endogenous peptides in mouse pancreatic dysfunction with aging.","volume":"23","author":"Hu","year":"2019","journal-title":"J Cell Physiol"},{"key":"61","doi-asserted-by":"publisher","first-page":"4156","DOI":"10.1007\/s12010-022-04005-4","article-title":"Data-Independent Acquisition-Based Mass Spectrometry (DIA-MS) for Quantitative Analysis of Human Intestinal Ischemia\/Reperfusion.","volume":"19","author":"Zhang","year":"2022","journal-title":"Appl Biochem Biotechnol"},{"key":"62","doi-asserted-by":"publisher","first-page":"818513","DOI":"10.3389\/fcell.2022.818513","article-title":"Remifentanil Promotes PDIA3 Expression by Activating p38MAPK to Inhibit Intestinal Ischemia\/Reperfusion-Induced Oxidative and Endoplasmic Reticulum Stress.","volume":"1","author":"Huang","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"63","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1021\/pr201025m","article-title":"Metabolic adaptation to a disruption in oxygen supply during myocardial ischemia and reperfusion is underpinned by temporal and quantitative changes in the cardiac proteome.","volume":"1","author":"Sze","year":"2012","journal-title":"J Proteome Res"},{"key":"64","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1016\/j.biopha.2018.06.091","article-title":"KGF inhibits hypoxia-induced intestinal epithelial cell apoptosis by upregulating AKT\/ERK pathway-dependent E-cadherin expression.","volume":"10","author":"Mei","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"65","doi-asserted-by":"publisher","first-page":"G339","DOI":"10.1152\/ajpgi.90607.2008","article-title":"Ischemia-mediated aggregation of the actin cytoskeleton is one of the major initial events resulting in ischemia-reperfusion injury.","volume":"29","author":"Tsokos","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"66","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/j.bbamcr.2017.03.007","article-title":"Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms.","volume":"186","author":"Ivanov","year":"2017","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"67","doi-asserted-by":"publisher","first-page":"6267","DOI":"10.3390\/ijms20246267","article-title":"The Microbiota and Cancer Cachexia.","volume":"2","author":"Trevino","year":"2019","journal-title":"Int J Mol Sci"},{"key":"68","doi-asserted-by":"publisher","first-page":"1880","DOI":"10.1007\/s10753-012-9510-1","article-title":"Lipopolysaccharide-induced bacterial translocation is intestine site-specific and associates with intestinal mucosal inflammation.","volume":"3","author":"Li","year":"2012","journal-title":"Inflammation"},{"key":"69","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1111\/jpn.13087","article-title":"Eleutheroside B increase tight junction proteins and anti-inflammatory cytokines expression in intestinal porcine jejunum epithelial cells (IPEC-J2).","volume":"10","author":"Jiang","year":"2019","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"key":"70","doi-asserted-by":"publisher","first-page":"101051","DOI":"10.1016\/j.tranon.2021.101051","article-title":"The remodelling of actin composition as a hallmark of cancer.","volume":"1","author":"Diaz","year":"2021","journal-title":"Transl Oncol"},{"key":"71","doi-asserted-by":"publisher","first-page":"e140604","DOI":"10.1172\/jci.insight.140604","article-title":"Pseudo-obstruction-inducing ACTG2R257C alters actin organization and function.","volume":"5","author":"Heuckeroth","year":"2020","journal-title":"JCI Insight"},{"key":"72","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1096\/fj.04-3260com","article-title":"Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process.","volume":"1","author":"Nusrat","year":"2005","journal-title":"FASEB J"},{"key":"73","first-page":"2006","article-title":"Adenosine A2B receptor modulates intestinal barrier function under hypoxic and ischemia\/reperfusion conditions.","volume":"7","author":"Yang","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"key":"74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0079-6107(02)00037-8","article-title":"Tight junction proteins.","volume":"8","author":"Jaramillo","year":"2003","journal-title":"Prog Biophys Mol Biol"},{"key":"75","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.semcdb.2014.08.011","article-title":"Architecture of tight junctions and principles of molecular composition.","volume":"3","author":"Anderson","year":"2014","journal-title":"Semin Cell Dev Biol"},{"key":"76","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1083\/jcb.123.6.1777","article-title":"Occludin: a novel integral membrane protein localizing at tight junctions.","volume":"12","author":"Tsukita","year":"1993","journal-title":"J Cell Biol"},{"key":"77","doi-asserted-by":"publisher","first-page":"G1054","DOI":"10.1152\/ajpgi.00055.2011","article-title":"Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier.","volume":"30","author":"Ma","year":"2011","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"78","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s40635-018-0203-4","article-title":"Tight junction structure, function, and assessment in the critically ill: a systematic review.","volume":"6","author":"Pierce","year":"2018","journal-title":"Intensive Care Med Exp"},{"key":"79","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1242\/jcs.113399","article-title":"Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1.","volume":"12","author":"Fanning","year":"2013","journal-title":"J Cell Sci"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T14:32:59Z","timestamp":1701873179000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,10]]},"references-count":79,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2023,11,30]]}},"alternative-id":["205200","37955663"],"URL":"https:\/\/doi.org\/10.18632\/aging.205200","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,10]]}}}