{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:30:12Z","timestamp":1710117012832},"reference-count":40,"publisher":"Impact Journals, LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"DOI":"10.18632\/aging.205271","type":"journal-article","created":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T20:04:23Z","timestamp":1710101063000},"source":"Crossref","is-referenced-by-count":0,"title":["Azilsartan improves urinary albumin excretion in hypertension mice"],"prefix":"10.18632","author":[{"given":"Jun","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfeng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjin","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaofeng","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Nephrology, People\u2019s Hospital of Ganzhou, Ganzhou 341001, Jiangxi Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2024,3,10]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1152\/physrev.00031.2016","article-title":"Role of the Immune System in Hypertension.","volume":"9","author":"Johnson","year":"2017","journal-title":"Physiol Rev"},{"key":"2","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1161\/CIRCRESAHA.116.303697","article-title":"Inflammation, immunity, and hypertensive end-organ damage.","volume":"11","author":"Harrison","year":"2015","journal-title":"Circ Res"},{"key":"3","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/S0140-6736(05)17789-7","article-title":"Chronic kidney disease: the global challenge.","volume":"36","author":"Bello","year":"2005","journal-title":"Lancet"},{"key":"4","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1146\/annurev-physiol-021317-121134","article-title":"Salt, Hypertension, and Immunity.","volume":"8","author":"Crowley","year":"2018","journal-title":"Annu Rev Physiol"},{"key":"5","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.cjca.2020.02.081","article-title":"Oxidative Stress: A Unifying Paradigm in Hypertension.","volume":"3","author":"Montezano","year":"2020","journal-title":"Can J Cardiol"},{"key":"6","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1124\/pr.117.014753","article-title":"Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.","volume":"7","author":"Robledinos-Ant\u00f3n","year":"2018","journal-title":"Pharmacol Rev"},{"key":"7","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1007\/s00467-018-4005-4","article-title":"Oxidative stress in chronic kidney disease.","volume":"3","author":"Bammens","year":"2019","journal-title":"Pediatr Nephrol"},{"key":"8","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1093\/eurheartj\/ehr003","article-title":"Renal function and target organ damage in hypertension.","volume":"3","author":"Bakris","year":"2011","journal-title":"Eur Heart J"},{"key":"9","doi-asserted-by":"publisher","first-page":"101266","DOI":"10.1016\/j.redox.2019.101266","article-title":"CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-\u03baB activation.","volume":"2","author":"Jiang","year":"2019","journal-title":"Redox Biol"},{"key":"10","doi-asserted-by":"publisher","first-page":"28848","DOI":"10.1074\/jbc.C500200200","article-title":"Inhibition of vascular permeability factor\/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2.","volume":"28","author":"Jain","year":"2005","journal-title":"J Biol Chem"},{"key":"11","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1084\/jem.20031132","article-title":"KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation.","volume":"19","author":"Jain","year":"2004","journal-title":"J Exp Med"},{"key":"12","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.tips.2019.02.004","article-title":"Targeting Mechanosensitive Transcription Factors in Atherosclerosis.","volume":"4","author":"Jin","year":"2019","journal-title":"Trends Pharmacol Sci"},{"key":"13","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1007\/s11906-010-0150-2","article-title":"Vascular endothelial function and hypertension: insights and directions.","volume":"1","author":"Widlansky","year":"2010","journal-title":"Curr Hypertens Rep"},{"key":"14","doi-asserted-by":"publisher","first-page":"762","DOI":"10.3390\/cells11050762","article-title":"Renoprotective Effect of KLF2 on Glomerular Endothelial Dysfunction in Hypertensive Nephropathy.","volume":"1","author":"Yang","year":"2022","journal-title":"Cells"},{"key":"15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/bs.podrm.2019.10.001","article-title":"Azilsartan medoxomil.","volume":"4","author":"Abdelhameed","year":"2020","journal-title":"Profiles Drug Subst Excip Relat Methodol"},{"key":"16","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1093\/jpp\/rgab097","article-title":"Azilsartan ameliorates ventricular hypertrophy in rats suffering from pressure overload-induced cardiac hypertrophy by activating the Keap1-Nrf2 signalling pathway.","volume":"7","author":"Luo","year":"2021","journal-title":"J Pharm Pharmacol"},{"key":"17","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.trsl.2014.06.003","article-title":"Cerebrovasculoprotective effects of azilsartan medoxomil in diabetes.","volume":"16","author":"Ergul","year":"2014","journal-title":"Transl Res"},{"key":"18","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1093\/ajh\/hpu016","article-title":"Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats.","volume":"2","author":"Imig","year":"2014","journal-title":"Am J Hypertens"},{"key":"19","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1021\/acsomega.0c03655","article-title":"Azilsartan Suppressed LPS-Induced Inflammation in U937 Macrophages through Suppressing Oxidative Stress and Inhibiting the TLR2\/MyD88 Signal Pathway.","volume":"6","author":"Wang","year":"2020","journal-title":"ACS Omega"},{"key":"20","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.neuint.2016.02.005","article-title":"Azilsartan, an angiotensin II type 1 receptor blocker, attenuates tert-butyl hydroperoxide-induced endothelial cell injury through inhibition of mitochondrial dysfunction and anti-inflammatory activity.","volume":"9","author":"Xie","year":"2016","journal-title":"Neurochem Int"},{"key":"21","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1161\/HYPERTENSIONAHA.120.16437","article-title":"IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone\/Salt-Induced Hypertension in Mice.","volume":"7","author":"Arumugam","year":"2021","journal-title":"Hypertension"},{"key":"22","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1038\/jcbfm.2015.154","article-title":"miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions.","volume":"3","author":"Persidsky","year":"2015","journal-title":"J Cereb Blood Flow Metab"},{"key":"23","doi-asserted-by":"publisher","first-page":"e48","DOI":"10.1161\/01.RES.0000159707.05637.a1","article-title":"Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function.","volume":"9","author":"Jain","year":"2005","journal-title":"Circ Res"},{"key":"24","doi-asserted-by":"publisher","first-page":"e0189221","DOI":"10.1371\/journal.pone.0189221","article-title":"Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells.","volume":"1","author":"Kim","year":"2017","journal-title":"PLoS One"},{"key":"25","doi-asserted-by":"publisher","first-page":"12996","DOI":"10.18632\/aging.202973","article-title":"Azilsartan ameliorates ox-LDL-induced endothelial dysfunction via promoting the expression of KLF2.","volume":"1","author":"Luo","year":"2021","journal-title":"Aging (Albany NY)"},{"key":"26","doi-asserted-by":"publisher","first-page":"9","DOI":"10.2169\/internalmedicine.43.9","article-title":"Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure.","volume":"4","author":"Nangaku","year":"2004","journal-title":"Intern Med"},{"key":"27","doi-asserted-by":"publisher","first-page":"109244","DOI":"10.1016\/j.vetmic.2021.109244","article-title":"Goose nephritic astrovirus infection increases autophagy, destroys intercellular junctions in renal tubular epithelial cells, and damages podocytes in the kidneys of infected goslings.","volume":"26","author":"Bao","year":"2021","journal-title":"Vet Microbiol"},{"key":"28","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1161\/hy1101.093423","article-title":"NADH\/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat.","volume":"3","author":"Webb","year":"2001","journal-title":"Hypertension"},{"key":"29","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1159\/000086411","article-title":"Oxidative stress and antioxidant treatment in hypertension and the associated renal damage.","volume":"2","author":"Meng","year":"2005","journal-title":"Am J Nephrol"},{"key":"30","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/S1875-5364(14)60053-4","article-title":"Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension.","volume":"1","author":"Wang","year":"2014","journal-title":"Chin J Nat Med"},{"key":"31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1097\/HJH.0000000000001613","article-title":"Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II\/high-salt-diet-induced hypertension.","volume":"3","author":"Ye","year":"2018","journal-title":"J Hypertens"},{"key":"32","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1152\/japplphysiol.00536.2015","article-title":"Intestinal epithelial barrier function and tight junction proteins with heat and exercise.","volume":"12","author":"Moseley","year":"2016","journal-title":"J Appl Physiol (1985)"},{"key":"33","doi-asserted-by":"publisher","first-page":"F20","DOI":"10.1152\/ajprenal.00052.2005","article-title":"Tight junction biology and kidney dysfunction.","volume":"29","author":"Ward","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"34","doi-asserted-by":"publisher","first-page":"1679","DOI":"10.1098\/rstb.2010.0025","article-title":"Claudin and occludin expression and function in the seminiferous epithelium.","volume":"36","author":"Hess","year":"2010","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"35","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1080\/21655979.2021.2012550","article-title":"Sitagliptin protects renal glomerular endothelial cells against high glucose-induced dysfunction and injury.","volume":"1","author":"Shao","year":"2022","journal-title":"Bioengineered"},{"key":"36","doi-asserted-by":"publisher","first-page":"5957","DOI":"10.1128\/MCB.15.11.5957","article-title":"Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Kr\u00fcppel-like factor: identification of a new multigene family.","volume":"1","author":"Lingrel","year":"1995","journal-title":"Mol Cell Biol"},{"key":"37","doi-asserted-by":"publisher","first-page":"29299","DOI":"10.1074\/jbc.M103670200","article-title":"Lung Kr\u00fcppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.","volume":"27","author":"Lingrel","year":"2001","journal-title":"J Biol Chem"},{"key":"38","doi-asserted-by":"publisher","first-page":"254","DOI":"10.3390\/biomedicines10020254","article-title":"The Role of KLF2 in the Regulation of Atherosclerosis Development and Potential Use of KLF2-Targeted Therapy.","volume":"1","author":"Orekhov","year":"2022","journal-title":"Biomedicines"},{"key":"39","doi-asserted-by":"publisher","first-page":"2383","DOI":"10.3390\/ijms18112383","article-title":"KLF2 in Regulation of NF-\u03baB-Mediated Immune Cell Function and Inflammation.","volume":"1","author":"Das","year":"2017","journal-title":"Int J Mol Sci"},{"key":"40","doi-asserted-by":"publisher","first-page":"3621","DOI":"10.1080\/21655979.2021.1948950","article-title":"Azilsartan protects against hyperglycemia-induced hyperpermeability of the blood-brain barrier.","volume":"1","author":"Chen","year":"2021","journal-title":"Bioengineered"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,10]],"date-time":"2024-03-10T20:04:27Z","timestamp":1710101067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,10]]},"references-count":40,"alternative-id":["205271"],"URL":"https:\/\/doi.org\/10.18632\/aging.205271","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,10]]}}}