{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:54:06Z","timestamp":1792133646045,"version":"4.4.0"},"reference-count":55,"publisher":"Impact Journals, LLC","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2024,1,31]]},"DOI":"10.18632\/aging.205407","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T17:34:40Z","timestamp":1705512880000},"page":"1276-1297","source":"Crossref","is-referenced-by-count":6,"title":["Molecular subgroup establishment and signature creation of lncRNAs associated with acetylation in lung adenocarcinoma"],"prefix":"10.18632","volume":"16","author":[{"given":"Hao","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changjian","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongtao","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghong","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yimeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolong","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Tangdu Hospital of Air Force Military Medical University, Xi\u2019an 71003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3322\/caac.21763","article-title":"Cancer statistics, 2023.","volume":"7","author":"Jemal","year":"2023","journal-title":"CA Cancer J Clin"},{"key":"2","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1038\/nature25183","article-title":"The biology and management of non-small cell lung cancer.","volume":"55","author":"Boshoff","year":"2018","journal-title":"Nature"},{"key":"3","doi-asserted-by":"publisher","first-page":"102237","DOI":"10.1016\/j.ctrv.2021.102237","article-title":"Adenocarcinoma spectrum lesions of the lung: Detection, pathology and treatment strategies.","volume":"9","author":"Rintoul","year":"2021","journal-title":"Cancer Treat Rev"},{"key":"4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/s12943-022-01519-7","article-title":"Methyltransferase like 7B is a potential therapeutic target for reversing EGFR-TKIs resistance in lung adenocarcinoma.","volume":"2","author":"Zou","year":"2022","journal-title":"Mol Cancer"},{"key":"5","doi-asserted-by":"publisher","first-page":"9332","DOI":"10.7150\/thno.47137","article-title":"USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer.","volume":"1","author":"Yang","year":"2020","journal-title":"Theranostics"},{"key":"6","doi-asserted-by":"publisher","first-page":"829057","DOI":"10.3389\/fimmu.2022.829057","article-title":"Immune- and Stemness-Related Genes Revealed by Comprehensive Analysis and Validation for Cancer Immunity and Prognosis and Its Nomogram in Lung Adenocarcinoma.","volume":"1","author":"Li","year":"2022","journal-title":"Front Immunol"},{"key":"7","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.7150\/ijbs.42080","article-title":"Ligand-receptor interaction atlas within and between tumor cells and T cells in lung adenocarcinoma.","volume":"1","author":"Jiang","year":"2020","journal-title":"Int J Biol Sci"},{"key":"8","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.","volume":"7","author":"Bray","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"9","doi-asserted-by":"publisher","first-page":"119504","DOI":"10.1016\/j.lfs.2021.119504","article-title":"Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy.","volume":"27","author":"Manyam","year":"2021","journal-title":"Life Sci"},{"key":"10","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/0092-8674(93)90051-q","article-title":"A positive role for histone acetylation in transcription factor access to nucleosomal DNA.","volume":"7","author":"Wolffe","year":"1993","journal-title":"Cell"},{"key":"11","doi-asserted-by":"publisher","first-page":"2220","DOI":"10.1038\/s41467-023-37805-1","article-title":"A VEL3 histone deacetylase complex establishes a maternal epigenetic state controlling progeny seed dormancy.","volume":"1","author":"Penfield","year":"2023","journal-title":"Nat Commun"},{"key":"12","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/nrm3931","article-title":"50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond.","volume":"1","author":"Ott","year":"2015","journal-title":"Nat Rev Mol Cell Biol"},{"key":"13","doi-asserted-by":"publisher","first-page":"106767","DOI":"10.1016\/j.phrs.2023.106767","article-title":"BRD4: New hope in the battle against glioblastoma.","volume":"19","author":"Chen","year":"2023","journal-title":"Pharmacol Res"},{"key":"14","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1038\/s41419-023-05582-w","article-title":"KAT8 acetylation-controlled lipolysis affects the invasive and migratory potential of colorectal cancer cells.","volume":"1","author":"Yang","year":"2023","journal-title":"Cell Death Dis"},{"key":"15","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1038\/s41392-023-01342-6","article-title":"Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies.","volume":"8","author":"Niu","year":"2023","journal-title":"Signal Transduct Target Ther"},{"key":"16","doi-asserted-by":"publisher","first-page":"114407","DOI":"10.1016\/j.biopha.2023.114407","article-title":"Long non-coding RNAs and gastric cancer: An update of potential biomarkers and therapeutic applications.","volume":"16","author":"Bazazzadeh","year":"2023","journal-title":"Biomed Pharmacother"},{"key":"17","doi-asserted-by":"publisher","first-page":"3021","DOI":"10.18632\/aging.204655","article-title":"lncRNA TUSC7 sponges miR-10a-5p and inhibits BDNF\/ERK pathway to suppress glioma cell proliferation and migration.","volume":"1","author":"Yang","year":"2023","journal-title":"Aging (Albany NY)"},{"key":"18","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s13059-023-02925-w","article-title":"A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA.","volume":"2","author":"Jiang","year":"2023","journal-title":"Genome Biol"},{"key":"19","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1038\/s41419-023-05790-4","article-title":"LncRNA UCA1 promotes keratinocyte-driven inflammation via suppressing METTL14 and activating the HIF-1\u03b1\/NF-\u03baB axis in psoriasis.","volume":"1","author":"Chen","year":"2023","journal-title":"Cell Death Dis"},{"key":"20","doi-asserted-by":"publisher","first-page":"110680","DOI":"10.1016\/j.cellsig.2023.110680","article-title":"LncRNA MEG3 regulates ASK1\/JNK axis-mediated apoptosis and autophagy via sponging miR-23a in granulosa cells of yak tertiary follicles.","volume":"10","author":"Yu","year":"2023","journal-title":"Cell Signal"},{"key":"21","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13045-019-0773-y","article-title":"LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p\/c-Myc axis.","volume":"1","author":"Huang","year":"2019","journal-title":"J Hematol Oncol"},{"key":"22","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1038\/s41418-019-0381-y","article-title":"The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1\u03b1.","volume":"2","author":"Liang","year":"2020","journal-title":"Cell Death Differ"},{"key":"23","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1038\/s41467-019-08554-x","article-title":"Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment.","volume":"1","author":"Montone","year":"2019","journal-title":"Nat Commun"},{"key":"24","doi-asserted-by":"publisher","first-page":"61","DOI":"10.2217\/fon-2018-0099","article-title":"Emerging targets in advanced non-small-cell lung cancer.","volume":"1","author":"Rossi","year":"2018","journal-title":"Future Oncol"},{"key":"25","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.canlet.2019.10.009","article-title":"Epidemiology of lung cancer and lung cancer screening programs in China and the United States.","volume":"46","author":"Powell","year":"2020","journal-title":"Cancer Lett"},{"key":"26","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.athoracsur.2017.08.045","article-title":"Thoracoscopic Surgery Versus Thoracotomy for Lung Cancer: Short-Term Outcomes of a Randomized Trial.","volume":"10","author":"Rong","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"27","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jtcvs.2018.11.124","article-title":"Initial results of pulmonary resection after neoadjuvant nivolumab in patients with resectable non-small cell lung cancer.","volume":"15","author":"Broderick","year":"2019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"28","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.lungcan.2018.02.008","article-title":"Neoadjuvant treatment followed by surgery versus definitive chemoradiation in stage IIIA-N2 non-small-cell lung cancer: A multi-institutional study by the oncologic group for the study of lung cancer (Spanish Radiation Oncology Society).","volume":"11","author":"Murcia-Mej\u00eda","year":"2018","journal-title":"Lung Cancer"},{"key":"29","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s40779-022-00412-0","article-title":"Melatonin inhibits ESCC tumor growth by mitigating the HDAC7\/\u03b2-catenin\/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability.","volume":"9","author":"Yang","year":"2022","journal-title":"Mil Med Res"},{"key":"30","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13046-022-02266-9","article-title":"HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of \u03b2-catenin-FGF18 pathway.","volume":"4","author":"Suda","year":"2022","journal-title":"J Exp Clin Cancer Res"},{"key":"31","doi-asserted-by":"publisher","first-page":"865975","DOI":"10.3389\/fimmu.2022.865975","article-title":"Lysine Acetylation\/Deacetylation Modification of Immune-Related Molecules in Cancer Immunotherapy.","volume":"1","author":"Yan","year":"2022","journal-title":"Front Immunol"},{"key":"32","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1186\/s12967-022-03711-1","article-title":"m6A-immune-related lncRNA prognostic signature for predicting immune landscape and prognosis of bladder cancer.","volume":"2","author":"Luo","year":"2022","journal-title":"J Transl Med"},{"key":"33","doi-asserted-by":"publisher","first-page":"880288","DOI":"10.3389\/fimmu.2022.880288","article-title":"Establishment of a lncRNA-Based Prognostic Gene Signature Associated With Altered Immune Responses in HCC.","volume":"1","author":"Dong","year":"2022","journal-title":"Front Immunol"},{"key":"34","doi-asserted-by":"publisher","first-page":"675545","DOI":"10.3389\/fonc.2021.675545","article-title":"Identification of a Ferroptosis-Related LncRNA Signature as a Novel Prognosis Model for Lung Adenocarcinoma.","volume":"1","author":"Zhao","year":"2021","journal-title":"Front Oncol"},{"key":"35","doi-asserted-by":"publisher","first-page":"4721","DOI":"10.2147\/OTT.S322998","article-title":"Identification and Experimental Validation of Immune-Associate lncRNAs for Predicting Prognosis in Cervical Cancer.","volume":"1","author":"Lu","year":"2021","journal-title":"Onco Targets Ther"},{"key":"36","doi-asserted-by":"publisher","first-page":"5827544","DOI":"10.1155\/2022\/5827544","article-title":"Identification of Immune-Related lncRNA Pairs and Construction and Validation of a New Prognostic Signature of Colon Cancer.","volume":"202","author":"Xie","year":"2022","journal-title":"Can J Gastroenterol Hepatol"},{"key":"37","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1080\/15384101.2022.2067675","article-title":"ADAMTS9-AS2 regulates PPP1R12B by adsorbing miR-196b-5p and affects cell cycle-related signaling pathways inhibiting the malignant process of esophageal cancer.","volume":"2","author":"Chen","year":"2022","journal-title":"Cell Cycle"},{"key":"38","doi-asserted-by":"publisher","first-page":"154346","DOI":"10.1016\/j.prp.2023.154346","article-title":"A review on the role of ADAMTS9-AS2 in different disorders.","volume":"24","author":"Mokhtari","year":"2023","journal-title":"Pathol Res Pract"},{"key":"39","doi-asserted-by":"publisher","first-page":"8541","DOI":"10.2147\/IJGM.S340683","article-title":"LncRNA ADAMTS9-AS2 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Lung Adenocarcinoma.","volume":"1","author":"Ye","year":"2021","journal-title":"Int J Gen Med"},{"key":"40","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/JLB.1MIA0321-164R","article-title":"Adipose-derived stem cell-derived extracellular vesicles inhibit neuroblastoma growth by regulating GABBR1 activity through LINC00622-mediated transcription factor AR.","volume":"11","author":"Yang","year":"2022","journal-title":"J Leukoc Biol"},{"key":"41","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1186\/s12967-022-03633-y","article-title":"MIR99AHG inhibits EMT in pulmonary fibrosis via the miR-136-5p\/USP4\/ACE2 axis.","volume":"2","author":"Liao","year":"2022","journal-title":"J Transl Med"},{"key":"42","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1080\/15384101.2022.2125751","article-title":"METTL3-mediated long non-coding RNA MIR99AHG methylation targets miR-4660 to promote bone marrow mesenchymal stem cell osteogenic differentiation.","volume":"2","author":"Zhao","year":"2023","journal-title":"Cell Cycle"},{"key":"43","doi-asserted-by":"crossref","unstructured":"Statement of Retraction: Long non-coding RNA LINC00968 reduces cell proliferation and migration and angiogenesis in breast cancer through up-regulation of PROX1 by reducing has-miR-423-5p. Cell Cycle. 2022; 21:2558. https:\/\/doi.org\/10.1080\/15384101.2022.2097799.","DOI":"10.1080\/15384101.2022.2097799"},{"key":"44","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/s12943-022-01581-1","article-title":"AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1\/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG\/miR-22-3p.","volume":"2","author":"Hermeking","year":"2022","journal-title":"Mol Cancer"},{"key":"45","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1038\/s41419-021-04105-9","article-title":"MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor.","volume":"1","author":"Fang","year":"2021","journal-title":"Cell Death Dis"},{"key":"46","doi-asserted-by":"publisher","first-page":"647236","DOI":"10.3389\/fonc.2021.647236","article-title":"Autophagy-Related Long Non-coding RNA Is a Prognostic Indicator for Bladder Cancer.","volume":"1","author":"Luo","year":"2021","journal-title":"Front Oncol"},{"key":"47","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.neurobiolaging.2019.05.023","article-title":"Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.","volume":"8","author":"Hu","year":"2019","journal-title":"Neurobiol Aging"},{"key":"48","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1186\/s12885-022-10232-z","article-title":"M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma.","volume":"2","author":"Li","year":"2022","journal-title":"BMC Cancer"},{"key":"49","doi-asserted-by":"publisher","first-page":"1163314","DOI":"10.3389\/fcell.2023.1163314","article-title":"An integrated bioinformatic analysis of bulk and single-cell sequencing clarifies immune microenvironment and metabolic profiles of lung adenocarcinoma to predict immunotherapy efficacy.","volume":"1","author":"Zheng","year":"2023","journal-title":"Front Cell Dev Biol"},{"key":"50","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1002\/ijc.34536","article-title":"Multi-target angiogenesis inhibitor combined with PD-1 inhibitors may benefit advanced non-small cell lung cancer patients in late line after failure of EGFR-TKI therapy.","volume":"15","author":"Zhong","year":"2023","journal-title":"Int J Cancer"},{"key":"51","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.immuni.2016.05.001","article-title":"Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.","volume":"4","author":"Kuchroo","year":"2016","journal-title":"Immunity"},{"key":"52","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1038\/nrc3239","article-title":"The blockade of immune checkpoints in cancer immunotherapy.","volume":"1","author":"Pardoll","year":"2012","journal-title":"Nat Rev Cancer"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201700297","article-title":"Silicon-containing analogs of camptothecin as anticancer agents.","volume":"35","author":"Lazarev","year":"2018","journal-title":"Arch Pharm (Weinheim)"},{"key":"54","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1517\/13543784.2011.617740","article-title":"Preclinical and clinical activity of the topoisomerase I inhibitor, karenitecin, in melanoma.","volume":"2","author":"Daud","year":"2011","journal-title":"Expert Opin Investig Drugs"},{"key":"55","doi-asserted-by":"publisher","first-page":"582447","DOI":"10.3389\/fphar.2021.582447","article-title":"The Optimal Adjuvant Strategy of Aidi Injection With Gemcitabine and Cisplatin in Advanced Non-small Cell Lung Cancer: A Meta-analysis of 70 Randomized Controlled Trials.","volume":"1","author":"Xiao","year":"2021","journal-title":"Front Pharmacol"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T17:54:47Z","timestamp":1707155687000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,17]]},"references-count":55,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,1,31]]}},"alternative-id":["205407","38240708"],"URL":"https:\/\/doi.org\/10.18632\/aging.205407","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,17]]}}}