{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:26:07Z","timestamp":1771658767879,"version":"3.50.1"},"reference-count":63,"publisher":"Impact Journals, LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"DOI":"10.18632\/aging.205475","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T16:59:36Z","timestamp":1706201976000},"source":"Crossref","is-referenced-by-count":3,"title":["Moxibustion prevents tripterygium glycoside-induced oligoasthenoteratozoospermia in rats via reduced oxidative stress and modulation of the Nrf2\/HO-1 signaling pathway"],"prefix":"10.18632","author":[{"given":"Shangjie","family":"Liang","sequence":"first","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqun","family":"Yin","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhizi","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yansu","family":"Fang","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ge","family":"Lu","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongxiao","family":"Li","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaoli","family":"Yin","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meihong","family":"Shen","sequence":"additional","affiliation":[{"name":"College of Acupuncture, Moxibustion and Tuina, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"},{"name":"Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1111\/andr.12502","article-title":"European Academy of Andrology guideline Management of oligo-astheno-teratozoospermia.","volume":"6","author":"Giwercman","year":"2018","journal-title":"Andrology"},{"key":"2","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/andr.12678","article-title":"Symptoms of sexual dysfunction among men from infertile couples: prevalence and association with testosterone deficiency.","volume":"8","author":"Giwercman","year":"2020","journal-title":"Andrology"},{"key":"3","doi-asserted-by":"publisher","first-page":"801125","DOI":"10.3389\/fendo.2021.801125","article-title":"Extensive Assessment of Underlying Etiological Factors in Primary Infertile Men Reduces the Proportion of Men With Idiopathic Infertility.","volume":"1","author":"Salonia","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"4","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s00404-017-4451-4","article-title":"Application of testosterone supplementation in semen to improve sperm motility in asthenozoospermic males.","volume":"29","author":"Choavaratana","year":"2017","journal-title":"Arch Gynecol Obstet"},{"key":"5","first-page":"1287","article-title":"The impact of exogenous testosterone supplementation on spermatogenesis in a rat model of oligoasthenospermia.","volume":"1","author":"Zuo","year":"2020","journal-title":"Int J Clin Exp Pathol"},{"key":"6","doi-asserted-by":"publisher","first-page":"106","DOI":"10.3978\/j.issn.2223-4683.2013.06.01","article-title":"Exogenous testosterone: a preventable cause of male infertility.","volume":"2","author":"Kim","year":"2013","journal-title":"Transl Androl Urol"},{"key":"7","doi-asserted-by":"publisher","first-page":"D1","DOI":"10.1530\/EJE-21-0362","article-title":"Functional hypogonadism in middle-aged and older men: testosterone treatment or not?","volume":"18","author":"Jones","year":"2021","journal-title":"Eur J Endocrinol"},{"key":"8","doi-asserted-by":"publisher","first-page":"799294","DOI":"10.3389\/fmolb.2021.799294","article-title":"The Impact of Oxidative Stress in Male Infertility.","volume":"8","author":"Fiorillo","year":"2022","journal-title":"Front Mol Biosci"},{"key":"9","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1007\/s12011-020-02251-3","article-title":"Impact of Coenzyme Q10 and Selenium on Seminal Fluid Parameters and Antioxidant Status in Men with Idiopathic Infertility.","volume":"19","author":"Sengupta","year":"2021","journal-title":"Biol Trace Elem Res"},{"key":"10","doi-asserted-by":"publisher","first-page":"479","DOI":"10.3390\/antiox12020479","article-title":"Blood Leukocyte ROS Production Reflects Seminal Fluid Oxidative Stress and Spermatozoa Dysfunction in Idiopathic Infertile Men.","volume":"1","author":"Fiorillo","year":"2023","journal-title":"Antioxidants (Basel)"},{"key":"11","doi-asserted-by":"publisher","first-page":"e68490","DOI":"10.1371\/journal.pone.0068490","article-title":"Comparison of oxidative stress\/DNA damage in semen and blood of fertile and infertile men.","volume":"8","author":"Olinski","year":"2013","journal-title":"PLoS One"},{"key":"12","doi-asserted-by":"publisher","first-page":"e13394","DOI":"10.1111\/and.13394","article-title":"The role of propolis against paclitaxel-induced oligospermia, sperm abnormality, oxidative stress and DNA damage in testes of male rats.","volume":"5","author":"Said","year":"2020","journal-title":"Andrologia"},{"key":"13","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s12906-019-2799-7","article-title":"Effects of Qilin pills on spermatogenesis, reproductive hormones, oxidative stress, and the TSSK2 gene in a rat model of oligoasthenospermia.","volume":"2","author":"Gu","year":"2020","journal-title":"BMC Complement Med Ther"},{"key":"14","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/s00441-022-03664-3","article-title":"Exploring Nrf2 as a therapeutic target in testicular dysfunction.","volume":"39","author":"Adeyemi","year":"2022","journal-title":"Cell Tissue Res"},{"key":"15","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.freeradbiomed.2022.10.314","article-title":"Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.","volume":"19","author":"Zhao","year":"2022","journal-title":"Free Radic Biol Med"},{"key":"16","doi-asserted-by":"publisher","first-page":"1559325819878537","DOI":"10.1177\/1559325819878537","article-title":"Astaxanthin Ameliorates the Lipopolysaccharides-Induced Subfertility in Mouse via Nrf2\/HO-1 Antioxidant Pathway.","volume":"1","author":"Zhuang","year":"2019","journal-title":"Dose Response"},{"key":"17","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.lfs.2019.05.040","article-title":"Moxibustion improves ovary function by suppressing apoptosis events and upregulating antioxidant defenses in natural aging ovary.","volume":"22","author":"Huang","year":"2019","journal-title":"Life Sci"},{"key":"18","doi-asserted-by":"publisher","first-page":"829409","DOI":"10.3389\/fimmu.2022.829409","article-title":"Comparison of Efficacy of Acupuncture-Related Therapy in the Treatment of Rheumatoid Arthritis: A Network Meta-Analysis of Randomized Controlled Trials.","volume":"1","author":"Wang","year":"2022","journal-title":"Front Immunol"},{"key":"19","doi-asserted-by":"publisher","first-page":"e049039","DOI":"10.1136\/bmjopen-2021-049039","article-title":"Effects of moxibustion on reproduction and metabolism of polycystic ovary syndrome: a protocol for meta-analysis and systematic review.","volume":"1","author":"Zhou","year":"2021","journal-title":"BMJ Open"},{"key":"20","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1142\/S0192415X21500300","article-title":"CD39\/CD73\/A2a Adenosine Metabolic Pathway: Targets for Moxibustion in Treating DSS-Induced Ulcerative Colitis.","volume":"4","author":"Yu","year":"2021","journal-title":"Am J Chin Med"},{"key":"21","first-page":"1140","article-title":"[Discussion on moxibustion with different dose].","volume":"3","author":"Wang","year":"2015","journal-title":"Zhongguo Zhen Jiu"},{"key":"22","doi-asserted-by":"publisher","first-page":"520","DOI":"10.13702\/j.1000-0607.180509","article-title":"[Parameters and connotations of quantity of mild moxibustion stimulation].","volume":"4","author":"Zhang","year":"2019","journal-title":"Zhen Ci Yan Jiu"},{"key":"23","doi-asserted-by":"publisher","first-page":"8817858","DOI":"10.1155\/2021\/8817858","article-title":"Moxibustion Ameliorates Ovarian Reserve in Rats by Mediating Nrf2\/HO-1\/NLRP3 Anti-Inflammatory Pathway.","volume":"202","author":"Shen","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"24","doi-asserted-by":"publisher","first-page":"3184785","DOI":"10.1155\/2020\/3184785","article-title":"Effect of Moxibustion on Hyperhomocysteinemia and Oxidative Stress Induced by High-Methionine Diet.","volume":"202","author":"Baixiao","year":"2020","journal-title":"Evid Based Complement Alternat Med"},{"key":"25","doi-asserted-by":"publisher","first-page":"6058","DOI":"10.1002\/jcp.29534","article-title":"Male fertility in Mus musculus requires the activity of TRYX5 in sperm migration into the oviduct.","volume":"23","author":"Wang","year":"2020","journal-title":"J Cell Physiol"},{"key":"26","doi-asserted-by":"publisher","first-page":"15221","DOI":"10.1038\/s41598-019-51772-y","article-title":"Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.","volume":"9","author":"Shao","year":"2019","journal-title":"Sci Rep"},{"key":"27","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1186\/s12864-016-2858-0","article-title":"Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015): Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.","volume":"1","author":"Alghamdi","year":"2016","journal-title":"BMC Genomics"},{"key":"28","doi-asserted-by":"publisher","first-page":"3021","DOI":"10.1002\/ar.25002","article-title":"Effect of moxa smoke on sperm parameters and oxidative stress in rats with asthenozoospermia.","volume":"30","author":"Zhao","year":"2023","journal-title":"Anat Rec (Hoboken)"},{"key":"29","doi-asserted-by":"publisher","first-page":"843","DOI":"10.13703\/j.0255-2930.2019.08.012","article-title":"[Effect on sperm quality of asthenospermia and oligospermia treated with grain-moxibustion combined with medicine therapy].","volume":"3","author":"Xia","year":"2019","journal-title":"Zhongguo Zhen Jiu"},{"key":"30","doi-asserted-by":"publisher","first-page":"873","DOI":"10.13703\/j.0255-2930.20210927-k0003","article-title":"[Warming-needle moxibustion with different lengths of moxa stick for asthenospermia with kidney deficiency and liver depression: a randomized controlled trial].","volume":"4","author":"Gao","year":"2022","journal-title":"Zhongguo Zhen Jiu"},{"key":"31","doi-asserted-by":"publisher","first-page":"163","DOI":"10.4103\/CJP.CJP_34_20","article-title":"Low-frequency electroacupuncture at acupoints guanyuan (CV4) and zhongji (CV3) lengthen ejaculatory latency and improves sexual behavior in male rats.","volume":"6","author":"Yeh","year":"2020","journal-title":"Chin J Physiol"},{"key":"32","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/s0254-6272(15)30034-0","article-title":"Effect of lit-moxa stimulation of Guanyuan (CV 4) acupoint on levels of lactic acid and superoxide dismutase in skeletal muscle of rats.","volume":"3","author":"Xiaohong","year":"2015","journal-title":"J Tradit Chin Med"},{"key":"33","doi-asserted-by":"publisher","first-page":"2343817","DOI":"10.1155\/2020\/2343817","article-title":"Mitochondrial Respiratory Chain and Its Regulatory Elements SIRT1 and SIRT3 Play Important Role in the Initial Process of Energy Conversion after Moxibustion at Local Skin.","volume":"202","author":"Yu","year":"2020","journal-title":"Evid Based Complement Alternat Med"},{"key":"34","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.3390\/antiox10071131","article-title":"Sperm Motility, Oxidative Status, and Mitochondrial Activity: Exploring Correlation in Different Species.","volume":"1","author":"Boni","year":"2021","journal-title":"Antioxidants (Basel)"},{"key":"35","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3109\/14647273.2016.1157629","article-title":"Pregnancy prediction by free sperm DNA and sperm DNA fragmentation in semen specimens of IVF\/ICSI-ET patients.","volume":"1","author":"Messinis","year":"2016","journal-title":"Hum Fertil (Camb)"},{"key":"36","doi-asserted-by":"publisher","first-page":"e14268","DOI":"10.1111\/and.14268","article-title":"Association among sperm chromatin condensation, sperm DNA fragmentation and 8-OHdG in seminal plasma and semen parameters in infertile men with oligoasthenoteratozoospermia.","volume":"5","author":"Guvenc","year":"2022","journal-title":"Andrologia"},{"key":"37","doi-asserted-by":"publisher","first-page":"357","DOI":"10.4103\/1008-682X.179252","article-title":"Current medical management of endocrine-related male infertility.","volume":"1","author":"K\u00f6hler","year":"2016","journal-title":"Asian J Androl"},{"key":"38","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1038\/nrurol.2017.69","article-title":"Oxidative stress and male infertility.","volume":"1","author":"Dada","year":"2017","journal-title":"Nat Rev Urol"},{"key":"39","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.13703\/j.0255-2930.2017.09.031","article-title":"[Startup mechanism of moxibustion warming and dredging function].","volume":"3","author":"Zhang","year":"2017","journal-title":"Zhongguo Zhen Jiu"},{"key":"40","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1136\/acupmed-2012-010142","article-title":"Evaluation of different moxibustion doses for lumbar disc herniation: multicentre randomised controlled trial of heat-sensitive moxibustion therapy.","volume":"3","author":"Zhang","year":"2012","journal-title":"Acupunct Med"},{"key":"41","doi-asserted-by":"publisher","first-page":"734","DOI":"10.13703\/j.0255-2930.2019.07.015","article-title":"[Dose-effect relationship in treatment of chronic neck pain with the direct moxibustion of small moxa cone].","volume":"3","author":"Ma","year":"2019","journal-title":"Zhongguo Zhen Jiu"},{"key":"42","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/978-3-030-89340-8_9","article-title":"Oxidative Stress and Idiopathic Male Infertility.","volume":"135","author":"Dutta","year":"2022","journal-title":"Adv Exp Med Biol"},{"key":"43","doi-asserted-by":"publisher","first-page":"442","DOI":"10.5152\/tud.2020.20296","article-title":"Do antioxidants improve serum sex hormones and total motile sperm count in idiopathic infertile men?","volume":"4","author":"\u00c7ayan","year":"2020","journal-title":"Turk J Urol"},{"key":"44","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1007\/s43032-020-00314-3","article-title":"Comparison of the Effect of Ceratonia siliqua L. (Carob) Syrup and Vitamin E on Sperm Parameters, Oxidative Stress Index, and Sex Hormones in Infertile Men: a Randomized Controlled Trial.","volume":"2","author":"Mirabi","year":"2021","journal-title":"Reprod Sci"},{"key":"45","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1530\/REP-23-0097","article-title":"Obesity induces male mice infertility via oxidative stress, apoptosis, and glycolysis.","volume":"16","author":"Ma","year":"2023","journal-title":"Reproduction"},{"key":"46","doi-asserted-by":"publisher","first-page":"1269530","DOI":"10.1155\/2022\/1269530","article-title":"Therapeutic Effects of Xianlu Oral Solution on Rats with Oligoasthenozoospermia through Alleviating Apoptosis and Oxidative Stress.","volume":"202","author":"Jiang","year":"2022","journal-title":"Evid Based Complement Alternat Med"},{"key":"47","doi-asserted-by":"publisher","first-page":"4365895","DOI":"10.1155\/2023\/4365895","article-title":"Diabetes-Induced Autophagy Dysregulation Engenders Testicular Impairment via Oxidative Stress.","volume":"202","author":"Tang","year":"2023","journal-title":"Oxid Med Cell Longev"},{"key":"48","doi-asserted-by":"publisher","first-page":"515","DOI":"10.13703\/j.0255-2930.20200404-k0004","article-title":"[Clinical observation of herb-separated moxibustion on segmental conception vessel combined with low-frequency TEAS for asthenospermia and oligospermia].","volume":"4","author":"Han","year":"2021","journal-title":"Zhongguo Zhen Jiu"},{"key":"49","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.ijheh.2014.08.006","article-title":"Effect of cigarette smoke on DNA damage, oxidative stress, and morphological alterations in mouse testis and spermatozoa.","volume":"21","author":"Micale","year":"2015","journal-title":"Int J Hyg Environ Health"},{"key":"50","doi-asserted-by":"publisher","first-page":"53","DOI":"10.13703\/j.0255-2930.20191128-k0005","article-title":"[Effect of moxibustion on Nrf2\/HO-1 signaling pathway in rats with diminished ovarian reserve].","volume":"4","author":"Shen","year":"2021","journal-title":"Zhongguo Zhen Jiu"},{"key":"51","doi-asserted-by":"publisher","first-page":"2772","DOI":"10.3390\/ijms18122772","article-title":"Nrf2, the Master Regulator of Anti-Oxidative Responses.","volume":"1","author":"von Knethen","year":"2017","journal-title":"Int J Mol Sci"},{"key":"52","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1007\/s43440-020-00096-0","article-title":"Fenofibrate ameliorates testicular damage in rats with streptozotocin-induced type 1 diabetes: role of HO-1 and p38 MAPK.","volume":"7","author":"Khalaf","year":"2020","journal-title":"Pharmacol Rep"},{"key":"53","doi-asserted-by":"publisher","first-page":"714892","DOI":"10.3389\/fphar.2021.714892","article-title":"Qiangjing Tablets Regulate Apoptosis and Oxidative StressKeap\/Nrf2 Pathway to Improve the Reproductive Function in Asthenospermia Rats.","volume":"1","author":"Chang","year":"2021","journal-title":"Front Pharmacol"},{"key":"54","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1007\/s12010-019-03052-8","article-title":"Therapeutic effects of moxibustion simultaneously targeting Nrf2 and NF-\u03baB in diabetic peripheral neuropathy.","volume":"18","author":"Tang","year":"2019","journal-title":"Appl Biochem Biotechnol"},{"key":"55","doi-asserted-by":"publisher","first-page":"119031","DOI":"10.1016\/j.lfs.2021.119031","article-title":"Activation of autophagy by sitagliptin attenuates cadmium-induced testicular impairment in rats: Targeting AMPK\/mTOR and Nrf2\/HO-1 pathways.","volume":"26","author":"Eid","year":"2021","journal-title":"Life Sci"},{"key":"56","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.joim.2022.01.007","article-title":"Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K\/AKT signaling pathway.","volume":"2","author":"Shen","year":"2022","journal-title":"J Integr Med"},{"key":"57","volume-title":"WHO laboratory manual for the examination and processing of human semen. 5th ed","author":"World Health Organization","year":"2010"},{"key":"58","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.7150\/thno.51869","article-title":"Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia.","volume":"1","author":"Xing","year":"2021","journal-title":"Theranostics"},{"key":"59","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.ecoenv.2018.08.109","article-title":"Sulphur dioxide and arsenic affect male reproduction via interfering with spermatogenesis in mice.","volume":"16","author":"Wang","year":"2018","journal-title":"Ecotoxicol Environ Saf"},{"key":"60","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/978-1-62703-038-0_14","article-title":"Sperm chromatin structure assay (SCSA\u00ae).","volume":"92","author":"Evenson","year":"2013","journal-title":"Methods Mol Biol"},{"key":"61","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1002\/j.1939-4640.2002.tb02599.x","article-title":"Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques.","volume":"2","author":"Jost","year":"2002","journal-title":"J Androl"},{"key":"62","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/j.taap.2017.06.019","article-title":"Maternal exposure to a mixture of persistent organic pollutants (POPs) affects testis histology, epididymal sperm count and induces sperm DNA fragmentation in mice.","volume":"32","author":"Ropstad","year":"2017","journal-title":"Toxicol Appl Pharmacol"},{"key":"63","doi-asserted-by":"publisher","first-page":"74","DOI":"10.3390\/ani10010074","article-title":"Maternal Exposure to T-2 Toxin Induces Changes in Antioxidant System and Testosterone Synthesis in the Testes of Mice Offspring.","volume":"1","author":"Li","year":"2019","journal-title":"Animals (Basel)"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T16:59:53Z","timestamp":1706201993000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,25]]},"references-count":63,"alternative-id":["205475"],"URL":"https:\/\/doi.org\/10.18632\/aging.205475","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,25]]}}}