{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T15:30:22Z","timestamp":1746459022039},"reference-count":40,"publisher":"Impact Journals, LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"DOI":"10.18632\/aging.205479","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T17:05:04Z","timestamp":1706547904000},"source":"Crossref","is-referenced-by-count":1,"title":["Identification of an immune-related eRNA prognostic signature for clear cell renal cell carcinoma"],"prefix":"10.18632","author":[{"given":"Yang","family":"Lv","sequence":"first","affiliation":[{"name":"Department of Urology, The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University, Suzhou 215228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Niu","sequence":"additional","affiliation":[{"name":"Central Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian 116021, China"},{"name":"Department of Pharmacy, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University, Suzhou 215228, China"},{"name":"Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenchuan","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Urology, The State Key Lab of Reproductive, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinghan","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Urology, The State Key Lab of Reproductive, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulin","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Children\u2019s Hospital of Nanjing Medical University, Nanjing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongqi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, The Affiliated Jiangsu Shengze Hospital of Nanjing Medical University, Suzhou 215228, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2024,1,29]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.eururo.2014.04.029","article-title":"Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity.","volume":"6","author":"Kutikov","year":"2015","journal-title":"Eur Urol"},{"key":"2","doi-asserted-by":"publisher","first-page":"507","DOI":"10.3322\/caac.21411","article-title":"Treatment of renal cell carcinoma: Current status and future directions.","volume":"6","author":"Rini","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"3","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1016\/j.eururo.2015.01.005","article-title":"EAU guidelines on renal cell carcinoma: 2014 update.","volume":"6","author":"Staehler","year":"2015","journal-title":"Eur Urol"},{"key":"4","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1093\/annonc\/mdz056","article-title":"Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up\u2020.","volume":"3","author":"Horwich","year":"2019","journal-title":"Ann Oncol"},{"key":"5","doi-asserted-by":"publisher","first-page":"17009","DOI":"10.1038\/nrdp.2017.9","article-title":"Renal cell carcinoma.","volume":"3","author":"Ficarra","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"6","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.","volume":"6","author":"Jemal","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"7","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1038\/s41581-020-0316-3","article-title":"The immunology of renal cell carcinoma.","volume":"1","author":"Finke","year":"2020","journal-title":"Nat Rev Nephrol"},{"key":"8","doi-asserted-by":"publisher","first-page":"4416","DOI":"10.1158\/1078-0432.CCR-16-2848","article-title":"Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma.","volume":"2","author":"Germain","year":"2017","journal-title":"Clin Cancer Res"},{"key":"9","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/nrc3246","article-title":"The determinants of tumour immunogenicity.","volume":"1","author":"Jaffee","year":"2012","journal-title":"Nat Rev Cancer"},{"key":"10","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S1470-2045(18)30778-2","article-title":"Patient-reported outcomes of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib (CheckMate 214): a randomised, phase 3 trial.","volume":"2","author":"Motzer","year":"2019","journal-title":"Lancet Oncol"},{"key":"11","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1038\/nature10887","article-title":"Modular regulatory principles of large non-coding RNAs.","volume":"48","author":"Rinn","year":"2012","journal-title":"Nature"},{"key":"12","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.7150\/ijbs.40769","article-title":"LncRNAs regulate metabolism in cancer.","volume":"1","author":"Jin","year":"2020","journal-title":"Int J Biol Sci"},{"key":"13","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1038\/s41418-018-0084-9","article-title":"LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.","volume":"2","author":"Bai","year":"2018","journal-title":"Cell Death Differ"},{"key":"14","doi-asserted-by":"publisher","first-page":"3965","DOI":"10.1158\/0008-5472.CAN-16-2634","article-title":"Long Noncoding RNA and Cancer: A New Paradigm.","volume":"7","author":"Mandal","year":"2017","journal-title":"Cancer Res"},{"key":"15","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1038\/nrg.2016.4","article-title":"Enhancers as non-coding RNA transcription units: recent insights and future perspectives.","volume":"1","author":"Rosenfeld","year":"2016","journal-title":"Nat Rev Genet"},{"key":"16","doi-asserted-by":"publisher","first-page":"4493","DOI":"10.7150\/ijbs.66181","article-title":"Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer.","volume":"1","author":"Jiang","year":"2021","journal-title":"Int J Biol Sci"},{"key":"17","doi-asserted-by":"publisher","first-page":"4562","DOI":"10.1038\/s41467-019-12543-5","article-title":"Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer.","volume":"1","author":"Mills","year":"2019","journal-title":"Nat Commun"},{"key":"18","doi-asserted-by":"publisher","first-page":"5661","DOI":"10.1038\/onc.2017.184","article-title":"LncRNA-mediated regulation of cell signaling in cancer.","volume":"3","author":"Mo","year":"2017","journal-title":"Oncogene"},{"key":"19","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1182\/blood.2018874503","article-title":"The enhancer RNAactivates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.","volume":"13","author":"Sanda","year":"2019","journal-title":"Blood"},{"key":"20","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.3390\/cancers14081978","article-title":"Enhancer RNAs (eRNAs) in Cancer: The Jacks of All Trades.","volume":"1","author":"Bertoni","year":"2022","journal-title":"Cancers (Basel)"},{"key":"21","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1080\/15384101.2015.1032650","article-title":"A PreSTIGEous use of LncRNAs to predict enhancers.","volume":"1","author":"Kraus","year":"2015","journal-title":"Cell Cycle"},{"key":"22","doi-asserted-by":"publisher","first-page":"347","DOI":"10.3390\/cancers11030347","article-title":", A Prognosis-Related Enhancer RNA in Squamous Cell Carcinoma of the Head and Neck.","volume":"1","author":"Nylander","year":"2019","journal-title":"Cancers (Basel)"},{"key":"23","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1111\/j.1349-7006.2011.01945.x","article-title":"Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma.","volume":"10","author":"Takeya","year":"2011","journal-title":"Cancer Sci"},{"key":"24","first-page":"5132","article-title":"Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity.","volume":"6","author":"Ohtani","year":"2001","journal-title":"Cancer Res"},{"key":"25","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3389\/fcell.2019.00377","article-title":"Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate.","volume":"7","author":"Li","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"26","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1517\/14712598.2015.1029452","article-title":"Enhancer-associated RNAs as therapeutic targets.","volume":"1","author":"Agami","year":"2015","journal-title":"Expert Opin Biol Ther"},{"key":"27","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/nature09033","article-title":"Widespread transcription at neuronal activity-regulated enhancers.","volume":"46","author":"Bito","year":"2010","journal-title":"Nature"},{"key":"28","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/s41594-020-0446-0","article-title":"Enhancer RNAs are an important regulatory layer of the epigenome.","volume":"2","author":"Lauberth","year":"2020","journal-title":"Nat Struct Mol Biol"},{"key":"29","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/j.molcel.2012.11.021","article-title":"eRNAs are required for p53-dependent enhancer activity and gene transcription.","volume":"4","author":"Agami","year":"2013","journal-title":"Mol Cell"},{"key":"30","doi-asserted-by":"publisher","first-page":"7319","DOI":"10.1073\/pnas.1324151111","article-title":"Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation.","volume":"11","author":"Kantoff","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"31","doi-asserted-by":"publisher","first-page":"657051","DOI":"10.3389\/fgene.2021.657051","article-title":"Identification and Validation of an Immune-Related eRNA Prognostic Signature for Hepatocellular Carcinoma.","volume":"1","author":"Zhang","year":"2021","journal-title":"Front Genet"},{"key":"32","doi-asserted-by":"publisher","first-page":"676845","DOI":"10.3389\/fgene.2021.676845","article-title":"A Robust Prognostic Gene Signature Based on eRNAs-Driven Genes in Prostate Cancer.","volume":"1","author":"Wang","year":"2021","journal-title":"Front Genet"},{"key":"33","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1038\/s41746-022-00704-8","article-title":"Integrating Internet multisource big data to predict the occurrence and development of COVID-19 cryptic transmission.","volume":"5","author":"Wu","year":"2022","journal-title":"NPJ Digit Med"},{"key":"34","doi-asserted-by":"publisher","first-page":"11971","DOI":"10.3390\/ijms231911971","article-title":"Development of a Hallmark Pathway-Related Gene Signature Associated with Immune Response for Lower Grade Gliomas.","volume":"2","author":"Xie","year":"2022","journal-title":"Int J Mol Sci"},{"key":"35","doi-asserted-by":"publisher","first-page":"5346","DOI":"10.3390\/cancers14215346","article-title":"A Novel m7G-Related Genes-Based Signature with Prognostic Value and Predictive Ability to Select Patients Responsive to Personalized Treatment Strategies in Bladder Cancer.","volume":"1","author":"Xie","year":"2022","journal-title":"Cancers (Basel)"},{"key":"36","doi-asserted-by":"publisher","first-page":"755","DOI":"10.3390\/cells12050755","article-title":"The Characteristics of Tumor Microenvironment Predict Survival and Response to Immunotherapy in Adrenocortical Carcinomas.","volume":"1","author":"Xie","year":"2023","journal-title":"Cells"},{"key":"37","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.3390\/genes13091602","article-title":"A Novel 3-Gene Signature for Identifying COVID-19 Patients Based on Bioinformatics and Machine Learning.","volume":"1","author":"Xie","year":"2022","journal-title":"Genes (Basel)"},{"key":"38","doi-asserted-by":"publisher","first-page":"D1086","DOI":"10.1093\/nar\/gkac942","article-title":"OrganoidDB: a comprehensive organoid database for the multi-perspective exploration of bulk and single-cell transcriptomic profiles of organoids.","volume":"5","author":"Pan","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"39","doi-asserted-by":"publisher","first-page":"633812","DOI":"10.3389\/fgene.2021.633812","article-title":"Immunogenomic Profiling Demonstrate AC003092.1 as an Immune-Related eRNA in Glioblastoma Multiforme.","volume":"1","author":"Dong","year":"2021","journal-title":"Front Genet"},{"key":"40","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1038\/s41419-018-1183-8","article-title":"Long noncoding RNA AC003092.1 promotes temozolomide chemosensitivity through miR-195\/TFPI-2 signaling modulation in glioblastoma.","volume":"9","author":"Guo","year":"2018","journal-title":"Cell Death Dis"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T17:05:08Z","timestamp":1706547908000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,29]]},"references-count":40,"alternative-id":["205479"],"URL":"https:\/\/doi.org\/10.18632\/aging.205479","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,29]]}}}