{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T12:08:34Z","timestamp":1788782914065,"version":"build-2803163510"},"reference-count":48,"publisher":"Impact Journals, LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"DOI":"10.18632\/aging.205713","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T15:55:31Z","timestamp":1713455731000},"source":"Crossref","is-referenced-by-count":3,"title":["An LRPPRC-HAPSTR1-PSMD14 interaction regulates tumor progression in ovarian cancer"],"prefix":"10.18632","author":[{"given":"Dongxiao","family":"Li","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.","volume":"6","author":"Jemal","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s13148-018-0602-0","article-title":"Epigenetic therapy for ovarian cancer: promise and progress.","volume":"1","author":"Chiappinelli","year":"2019","journal-title":"Clin Epigenetics"},{"key":"3","doi-asserted-by":"publisher","first-page":"12041","DOI":"10.3390\/ijms231912041","article-title":"Molecular Biomarkers for the Early Detection of Ovarian Cancer.","volume":"2","author":"Chan","year":"2022","journal-title":"Int J Mol Sci"},{"key":"4","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s13402-020-00513-9","article-title":"Current insights into the metastasis of epithelial ovarian cancer - hopes and hurdles.","volume":"4","author":"Pasdar","year":"2020","journal-title":"Cell Oncol (Dordr)"},{"key":"5","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/s41419-022-04510-8","article-title":"Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion.","volume":"1","author":"Chang","year":"2022","journal-title":"Cell Death Dis"},{"key":"6","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1038\/s41392-022-00975-3","article-title":"Targeting non-coding RNAs to overcome cancer therapy resistance.","volume":"7","author":"Calin","year":"2022","journal-title":"Signal Transduct Target Ther"},{"key":"7","doi-asserted-by":"publisher","first-page":"2910","DOI":"10.3892\/ol.2015.3137","article-title":"Hybrid-polymerase chain reaction to identify novel target genes of miR-134 in paclitaxel resistant human ovarian carcinoma cells.","volume":"9","author":"Chang","year":"2015","journal-title":"Oncol Lett"},{"key":"8","doi-asserted-by":"publisher","first-page":"3154","DOI":"10.1016\/j.febslet.2015.08.047","article-title":"Down-regulated expression of miR-134 contributes to paclitaxel resistance in human ovarian cancer cells.","volume":"58","author":"Wang","year":"2015","journal-title":"FEBS Lett"},{"key":"9","doi-asserted-by":"publisher","first-page":"e2111262119","DOI":"10.1073\/pnas.2111262119","article-title":"C16orf72\/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.","volume":"11","author":"Cho","year":"2022","journal-title":"Proc Natl Acad Sci USA"},{"key":"10","doi-asserted-by":"publisher","first-page":"112496","DOI":"10.1016\/j.celrep.2023.112496","article-title":"HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.","volume":"4","author":"Bennett","year":"2023","journal-title":"Cell Rep"},{"key":"11","doi-asserted-by":"publisher","first-page":"e13331","DOI":"10.1111\/acel.13331","article-title":"A novel p53 regulator, C16ORF72\/TAPR1, buffers against telomerase inhibition.","volume":"2","author":"Harrington","year":"2021","journal-title":"Aging Cell"},{"key":"12","doi-asserted-by":"publisher","first-page":"4773","DOI":"10.1158\/0008-5472.CAN-16-2597","article-title":"Huwe1 Sustains Normal Ovarian Epithelial Cell Transformation and Tumor Growth through the Histone H1.3-H19 Cascade.","volume":"7","author":"Zhao","year":"2017","journal-title":"Cancer Res"},{"key":"13","doi-asserted-by":"publisher","first-page":"4028","DOI":"10.3390\/ijms21114028","article-title":"Regulation of Deubiquitinating Enzymes by Post-Translational Modifications.","volume":"2","author":"Kim","year":"2020","journal-title":"Int J Mol Sci"},{"key":"14","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1038\/s41416-022-01829-z","article-title":"POH1\/Rpn11\/PSMD14: a journey from basic research in fission yeast to a prognostic marker and a druggable target in cancer cells.","volume":"12","author":"Buetti-Dinh","year":"2022","journal-title":"Br J Cancer"},{"key":"15","doi-asserted-by":"publisher","first-page":"3639","DOI":"10.1002\/1878-0261.13076","article-title":"Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM2.","volume":"1","author":"Yang","year":"2021","journal-title":"Mol Oncol"},{"key":"16","doi-asserted-by":"publisher","first-page":"166594","DOI":"10.1016\/j.bbadis.2022.166594","article-title":"Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC.","volume":"186","author":"Song","year":"2023","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"17","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1186\/s12967-023-04349-3","article-title":"A traditional gynecological medicine inhibits ovarian cancer progression and eliminates cancer stem cells via the LRPPRC-OXPHOS axis.","volume":"2","author":"Gu","year":"2023","journal-title":"J Transl Med"},{"key":"18","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/pro.3978","article-title":"The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions.","volume":"3","author":"Chatr-Aryamontri","year":"2021","journal-title":"Protein Sci"},{"key":"19","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1097\/PAS.0000000000001929","article-title":"NTRK -Rearranged Uterine Sarcomas: Clinicopathologic Features of 15 Cases, Literature Review, and Risk Stratification.","volume":"4","author":"Kolin","year":"2022","journal-title":"Am J Surg Pathol"},{"key":"20","doi-asserted-by":"publisher","first-page":"e2384","DOI":"10.1038\/cddis.2016.289","article-title":"The Fra-1-miR-134-SDS22 feedback loop amplifies ERK\/JNK signaling and reduces chemosensitivity in ovarian cancer cells.","volume":"7","author":"Tang","year":"2016","journal-title":"Cell Death Dis"},{"key":"21","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1007\/s13238-014-0088-2","article-title":"MicroRNA-495 induces breast cancer cell migration by targeting JAM-A.","volume":"5","author":"Hou","year":"2014","journal-title":"Protein Cell"},{"key":"22","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1083\/jcb.200601018","article-title":"The epithelial-mesenchymal transition: new insights in signaling, development, and disease.","volume":"17","author":"Thompson","year":"2006","journal-title":"J Cell Biol"},{"key":"23","doi-asserted-by":"publisher","first-page":"110909","DOI":"10.1016\/j.biopha.2020.110909","article-title":"EMT, cancer stem cells and autophagy; The three main axes of metastasis.","volume":"13","author":"Jaghi","year":"2021","journal-title":"Biomed Pharmacother"},{"key":"24","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.apsb.2015.07.005","article-title":"Cancer metastases: challenges and opportunities.","volume":"5","author":"Guan","year":"2015","journal-title":"Acta Pharm Sin B"},{"key":"25","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1038\/nrm3758","article-title":"Molecular mechanisms of epithelial-mesenchymal transition.","volume":"1","author":"Derynck","year":"2014","journal-title":"Nat Rev Mol Cell Biol"},{"key":"26","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation.","volume":"14","author":"Weinberg","year":"2011","journal-title":"Cell"},{"key":"27","doi-asserted-by":"publisher","first-page":"3903","DOI":"10.3390\/ijms22083903","article-title":"Mitophagy in Human Diseases.","volume":"2","author":"Monsalve","year":"2021","journal-title":"Int J Mol Sci"},{"key":"28","doi-asserted-by":"publisher","first-page":"5634724","DOI":"10.1155\/2022\/5634724","article-title":"Mitochondrial Dysfunction Pathway Alterations Offer Potential Biomarkers and Therapeutic Targets for Ovarian Cancer.","volume":"202","author":"Zhan","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"29","doi-asserted-by":"publisher","first-page":"119233","DOI":"10.1016\/j.bbamcr.2022.119233","article-title":"The fate of damaged mitochondrial DNA in the cell.","volume":"186","author":"He","year":"2022","journal-title":"Biochim Biophys Acta Mol Cell Res"},{"key":"30","doi-asserted-by":"publisher","first-page":"379","DOI":"10.3390\/cells8040379","article-title":"Mitochondrial DNA: Distribution, Mutations, and Elimination.","volume":"8","author":"Song","year":"2019","journal-title":"Cells"},{"key":"31","doi-asserted-by":"publisher","first-page":"166431","DOI":"10.1016\/j.bbadis.2022.166431","article-title":"Autophagy and EMT in cancer and metastasis: Who controls whom?","volume":"186","author":"Ghavami","year":"2022","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"32","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.cell.2016.06.028","article-title":"EMT: 2016.","volume":"16","author":"Thiery","year":"2016","journal-title":"Cell"},{"key":"33","doi-asserted-by":"publisher","first-page":"545","DOI":"10.3389\/fcell.2020.00545","article-title":"The Autophagy Machinery Contributes to E-cadherin Turnover in Breast Cancer.","volume":"8","author":"Santarosa","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"34","doi-asserted-by":"publisher","first-page":"e1880","DOI":"10.1038\/cddis.2015.249","article-title":"Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation.","volume":"6","author":"Alonzi","year":"2015","journal-title":"Cell Death Dis"},{"key":"35","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.4161\/auto.32171","article-title":"Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition.","volume":"1","author":"He","year":"2014","journal-title":"Autophagy"},{"key":"36","doi-asserted-by":"publisher","first-page":"12424","DOI":"10.1021\/jacs.8b05147","article-title":"Cell-Permeable Activity-Based Ubiquitin Probes Enable Intracellular Profiling of Human Deubiquitinases.","volume":"14","author":"Zhuang","year":"2018","journal-title":"J Am Chem Soc"},{"key":"37","doi-asserted-by":"publisher","first-page":"102201","DOI":"10.1016\/j.redox.2021.102201","article-title":"LRPPRC regulates redox homeostasis via the circANKHD1\/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis.","volume":"4","author":"Yao","year":"2021","journal-title":"Redox Biol"},{"key":"38","doi-asserted-by":"publisher","first-page":"e51780","DOI":"10.15252\/embr.202051780","article-title":"Snail enhances arginine synthesis by inhibiting ubiquitination-mediated degradation of ASS1.","volume":"2","author":"Hou","year":"2021","journal-title":"EMBO Rep"},{"key":"39","doi-asserted-by":"publisher","first-page":"2655","DOI":"10.7150\/thno.48375","article-title":"Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1\/Akt\/SOX2-mediated stemness.","volume":"1","author":"Zhang","year":"2021","journal-title":"Theranostics"},{"key":"40","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.canlet.2019.10.025","article-title":"Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2.","volume":"46","author":"Yin","year":"2020","journal-title":"Cancer Lett"},{"key":"41","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.4161\/epi.29675","article-title":"ABCB1 regulation through LRPPRC is influenced by the methylation status of the GC -100 box in its promoter.","volume":"9","author":"Abdelhay","year":"2014","journal-title":"Epigenetics"},{"key":"42","doi-asserted-by":"publisher","first-page":"1144774","DOI":"10.3389\/fimmu.2023.1144774","article-title":"LRPPRC facilitates tumor progression and immune evasion through upregulation of m6A modification of PD-L1 mRNA in hepatocellular carcinoma.","volume":"1","author":"Li","year":"2023","journal-title":"Front Immunol"},{"key":"43","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1007\/s11357-023-00742-4","article-title":"Discovery and ranking of the most robust prognostic biomarkers in serous ovarian cancer.","volume":"4","author":"Gy\u0151rffy","year":"2023","journal-title":"Geroscience"},{"key":"44","doi-asserted-by":"publisher","first-page":"D956","DOI":"10.1093\/nar\/gkx1090","article-title":"LinkedOmics: analyzing multi-omics data within and across 32 cancer types.","volume":"4","author":"Zhang","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"45","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.","volume":"1","author":"Chanda","year":"2019","journal-title":"Nat Commun"},{"key":"46","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters.","volume":"1","author":"He","year":"2012","journal-title":"OMICS"},{"key":"47","doi-asserted-by":"publisher","first-page":"D1420","DOI":"10.1093\/nar\/gkaa1020","article-title":"TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment.","volume":"4","author":"Zhang","year":"2021","journal-title":"Nucleic Acids Res"},{"key":"48","doi-asserted-by":"publisher","first-page":"W509","DOI":"10.1093\/nar\/gkaa407","article-title":"TIMER2.0 for analysis of tumor-infiltrating immune cells.","volume":"4","author":"Liu","year":"2020","journal-title":"Nucleic Acids Res"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T15:55:34Z","timestamp":1713455734000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,18]]},"references-count":48,"alternative-id":["205713"],"URL":"https:\/\/doi.org\/10.18632\/aging.205713","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,18]]}}}