{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:51:59Z","timestamp":1791892319969,"version":"4.3.4"},"reference-count":41,"publisher":"Impact Journals, LLC","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aging"],"published-print":{"date-parts":[[2024,5,30]]},"DOI":"10.18632\/aging.205846","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T13:55:30Z","timestamp":1716386130000},"page":"8866-8879","source":"Crossref","is-referenced-by-count":7,"title":["Associations of collagen type 1 \u03b11 gene polymorphisms and musculoskeletal soft tissue injuries: a meta-analysis with trial sequential analysis"],"prefix":"10.18632","volume":"16","author":[{"given":"Rui","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shutao","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Xinjiang Medical University First Affiliated Hospital, Urumqi, Xinjiang 830054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazierhan","family":"Shaxika","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aihaiti","family":"Aizezi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Center, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830001, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2024,5,22]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s12891-018-1969-y","article-title":"Prevalence of adolescent physical activity-related injuries in sports, leisure time, and school: the National Physical Activity Behaviour Study for children and Adolescents.","volume":"1","author":"Parkkari","year":"2018","journal-title":"BMC Musculoskelet Disord"},{"key":"2","doi-asserted-by":"publisher","first-page":"1265","DOI":"10.1136\/bjsports-2017-097956","article-title":"Sports injury and illness incidence in the Rio de Janeiro 2016 Olympic Summer Games: A prospective study of 11274 athletes from 207 countries.","volume":"5","author":"Engebretsen","year":"2017","journal-title":"Br J Sports Med"},{"key":"3","doi-asserted-by":"publisher","first-page":"2325967116684776","DOI":"10.1177\/2325967116684776","article-title":"Cost of Outpatient Arthroscopic Anterior Cruciate Ligament Reconstruction Among Commercially Insured Patients in the United States, 2005-2013.","volume":"5","author":"Spang","year":"2017","journal-title":"Orthop J Sports Med"},{"key":"4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s40798-017-0087-y","article-title":"Biomedical Risk Factors of Achilles Tendinopathy in Physically Active People: a Systematic Review.","volume":"3","author":"Hughes","year":"2017","journal-title":"Sports Med Open"},{"key":"5","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1136\/bjsports-2018-099991","article-title":"Clinical risk factors for Achilles tendinopathy: a systematic review.","volume":"5","author":"de Vos","year":"2019","journal-title":"Br J Sports Med"},{"key":"6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1159\/000445243","article-title":"Genes and Musculoskeletal Soft-Tissue Injuries.","volume":"6","author":"September","year":"2016","journal-title":"Med Sport Sci"},{"key":"7","doi-asserted-by":"publisher","first-page":"663","DOI":"10.3390\/life12050663","article-title":"Tendon and Ligament Genetics: How Do They Contribute to Disease and Injury? A Narrative Review.","volume":"1","author":"Collins","year":"2022","journal-title":"Life (Basel)"},{"key":"8","doi-asserted-by":"publisher","first-page":"2642","DOI":"10.3390\/polym13162642","article-title":"Current Insights into Collagen Type I.","volume":"1","author":"Bahari","year":"2021","journal-title":"Polymers (Basel)"},{"key":"9","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/j.1600-0838.2005.00439.x","article-title":"The COL5A1 gene and Achilles tendon pathology.","volume":"1","author":"Collins","year":"2006","journal-title":"Scand J Med Sci Sports"},{"key":"10","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/tsm2.13","article-title":"Genetic variation in candidate genes and patellar tendinopathy: Prospective cohort study of 126 elite volleyball players.","volume":"1","author":"Bahr","year":"2018","journal-title":"Transl Sports Med"},{"key":"11","doi-asserted-by":"publisher","first-page":"15","DOI":"10.11138\/mltj\/2018.8.1.015","article-title":"Are COL1A1 gene polymorphisms associated with anterior cruciate ligament tear in the Indian population? Results of a preliminary case-control study.","volume":"8","author":"Bammidi","year":"2019","journal-title":"Muscles Ligaments Tendons J"},{"key":"12","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1177\/0363546518808467","article-title":"No Association Between Risk of Anterior Cruciate Ligament Rupture and Selected Candidate Collagen Gene Variants in Female Elite Athletes From High-Risk Team Sports.","volume":"4","author":"Bahr","year":"2019","journal-title":"Am J Sports Med"},{"key":"13","doi-asserted-by":"publisher","first-page":"2290","DOI":"10.1002\/jor.24621","article-title":"Functional COL1A1 variants are associated with the risk of acute musculoskeletal soft tissue injuries.","volume":"3","author":"September","year":"2020","journal-title":"J Orthop Res"},{"key":"14","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s43465-020-00119-1","article-title":"COLIA1\u2009+\u20091245 G\u2009>\u2009T Sp1 Binding Site Polymorphism is Not Associated with ACL Injury Risks Among Indian Athletes.","volume":"5","author":"Amrathlal","year":"2020","journal-title":"Indian J Orthop"},{"key":"15","doi-asserted-by":"publisher","first-page":"515","DOI":"10.4085\/1062-6050-335-18","article-title":"Correlations Between the Genetic Variations in theGenes and Anterior Cruciate Ligament Injury in Chinese Patients","volume":"5","author":"Zhao","year":"2020","journal-title":"J Athl Train"},{"key":"16","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.3390\/genes12071056","article-title":"Interactions between Gene Variants within theandGenes and Musculoskeletal Injuries in Physically Active Caucasian.","volume":"1","author":"Leo\u0144ska-Duniec","year":"2021","journal-title":"Genes (Basel)"},{"key":"17","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1249\/MSS.0000000000002658","article-title":"Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant.","volume":"5","author":"Zempo","year":"2021","journal-title":"Med Sci Sports Exerc"},{"key":"18","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1186\/s13018-022-03341-9","article-title":"Anterior cruciate ligament injury and its postoperative outcomes are not associated with polymorphism in COL1A1 rs1107946 (G\/T): a case-control study in the Middle East elite athletes.","volume":"1","author":"Akbari-Aghdam","year":"2022","journal-title":"J Orthop Surg Res"},{"key":"19","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12891-022-05105-2","article-title":"Influence of type I collagen polymorphisms and risk of anterior cruciate ligament rupture in athletes: a case-control study.","volume":"2","author":"Cossich","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"key":"20","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1038\/sj.ejhg.5201410","article-title":"Hardy-Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power.","volume":"1","author":"Ioannidis","year":"2005","journal-title":"Eur J Hum Genet"},{"key":"21","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1080\/08820139.2020.1869253","article-title":"Lack of Associations betweenGene Polymorphisms and Ankylosing Spondylitis: A Meta-analysis with Trial Sequential Analysis.","volume":"5","author":"Sheng","year":"2022","journal-title":"Immunol Invest"},{"key":"22","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.gene.2013.12.014","article-title":"Is Sp1 binding site polymorphism within COL1A1 gene associated with tennis elbow?","volume":"53","author":"Akseki","year":"2014","journal-title":"Gene"},{"key":"23","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.jsams.2012.10.004","article-title":"Gene variants within the COL1A1 gene are associated with reduced anterior cruciate ligament injury in professional soccer players.","volume":"1","author":"Eynon","year":"2013","journal-title":"J Sci Med Sport"},{"key":"24","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1177\/0363546508320805","article-title":"Type I collagen alpha1 Sp1 polymorphism and the risk of cruciate ligament ruptures or shoulder dislocations.","volume":"3","author":"Micha\u00eblsson","year":"2008","journal-title":"Am J Sports Med"},{"key":"25","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1123\/jsr.2015-0151","article-title":"Is the Combination of COL1A1 Gene Polymorphisms a Marker of Injury Risk?","volume":"2","author":"Cieszczyk","year":"2017","journal-title":"J Sport Rehabil"},{"key":"26","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1055\/s-0042-1757959","article-title":"Genetic Polymorphisms ingene and the Risk of Tendinopathy: Case-Control Study.","volume":"5","author":"Perini","year":"2023","journal-title":"Rev Bras Ortop (Sao Paulo)"},{"key":"27","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.3390\/genes14071418","article-title":"Collagen Gene Variants and Anterior Cruciate Ligament Rupture in Italian Athletes: A Preliminary Report.","volume":"1","author":"Cal\u00f2","year":"2023","journal-title":"Genes (Basel)"},{"key":"28","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1177\/0363546504265678","article-title":"The familial predisposition toward tearing the anterior cruciate ligament: a case control study.","volume":"3","author":"Fowler","year":"2005","journal-title":"Am J Sports Med"},{"key":"29","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.jse.2021.10.008","article-title":"The role of familial predisposition in imaging-confirmed atraumatic rotator cuff tears.","volume":"3","author":"Khazzam","year":"2022","journal-title":"J Shoulder Elbow Surg"},{"key":"30","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/B978-0-12-816193-7.00015-4","article-title":"Chapter Fifteen - Genetics of musculoskeletal soft tissue injuries: Current status, challenges, and future directions.","author":"September","year":"2019","journal-title":"Sports, Exercise, and Nutritional Genomics"},{"key":"31","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.3390\/biom11091279","article-title":"The Role of Polymorphisms in Collagen-Encoding Genes in Intervertebral Disc Degeneration.","volume":"1","author":"Nasyrova","year":"2021","journal-title":"Biomolecules"},{"key":"32","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1186\/s13018-021-02724-8","article-title":"Association between polymorphisms of collagen genes and susceptibility to intervertebral disc degeneration: a meta-analysis.","volume":"1","author":"Zhang","year":"2021","journal-title":"J Orthop Surg Res"},{"key":"33","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1111\/1756-185X.13052","article-title":"Association of collagen type I alpha 1 +1245G\/T polymorphism and osteoporosis risk in post-menopausal women: a meta-analysis.","volume":"2","author":"Zhou","year":"2017","journal-title":"Int J Rheum Dis"},{"key":"34","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1002\/art.21011","article-title":"Type I collagen alpha1 Sp1 transcription factor binding site polymorphism is associated with reduced risk of hip osteoarthritis defined by severe joint space narrowing in elderly women.","volume":"5","author":"Lane","year":"2005","journal-title":"Arthritis Rheum"},{"key":"35","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1002\/humu.1124","article-title":"Thirty-three novel COL1A1 and COL1A2 mutations in patients with osteogenesis imperfecta types I-IV.","volume":"1","author":"Glorieux","year":"2001","journal-title":"Hum Mutat"},{"key":"36","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1242\/jcs.95.4.649","article-title":"Collagen fibrillogenesis in vitro: interaction of types I and V collagen regulates fibril diameter.","volume":"9","author":"Linsenmayer","year":"1990","journal-title":"J Cell Sci"},{"key":"37","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1172\/JCI10347","article-title":"A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality.","volume":"10","author":"Ralston","year":"2001","journal-title":"J Clin Invest"},{"key":"38","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/s0945-053x(01)00128-7","article-title":"Multiple changes in gene expression in chronic human Achilles tendinopathy.","volume":"2","author":"Riley","year":"2001","journal-title":"Matrix Biol"},{"key":"39","doi-asserted-by":"publisher","first-page":"902","DOI":"10.1016\/j.bone.2004.12.012","article-title":"In vitro functional assay of alleles and haplotypes of two COL1A1-promoter SNPs.","volume":"3","author":"Balcells","year":"2005","journal-title":"Bone"},{"key":"40","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1093\/hmg\/ddp205","article-title":"Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis.","volume":"1","author":"Ralston","year":"2009","journal-title":"Hum Mol Genet"},{"key":"41","doi-asserted-by":"publisher","first-page":"27627","DOI":"10.18632\/oncotarget.15271","article-title":"Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis.","volume":"8","author":"Liu","year":"2017","journal-title":"Oncotarget"}],"container-title":["Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205846","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T15:47:10Z","timestamp":1717602430000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aging-us.com\/lookup\/doi\/10.18632\/aging.205846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,22]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,5,30]]}},"alternative-id":["205846","38787354"],"URL":"https:\/\/doi.org\/10.18632\/aging.205846","relation":{},"ISSN":["1945-4589"],"issn-type":[{"value":"1945-4589","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,22]]}}}