{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T09:14:25Z","timestamp":1749546865656},"reference-count":63,"publisher":"Impact Journals, LLC","issue":"5-6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Cancer"],"published-print":{"date-parts":[[2015,5,4]]},"DOI":"10.18632\/genesandcancer.63","type":"journal-article","created":{"date-parts":[[2015,12,17]],"date-time":"2015-12-17T15:26:38Z","timestamp":1450365998000},"page":"254-264","source":"Crossref","is-referenced-by-count":6,"title":["PSCA s2294008 C&gt;T and rs2976392 G&gt;A polymorphisms contribute to cancer susceptibility: evidence from published studies"],"prefix":"10.18632","volume":"6","author":[{"given":"Yong","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang-Sheng","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-Xi","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Molecular Epidemiology Laboratory and Laboratory Medicine, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Wen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin-Hui","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi-Qiu","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo-Sheng","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He-Ping","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"},{"name":"Department of Medical Imaging, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D. Global cancer statistics. CA Cancer J Clin. 2011; 61(2):69-90. [PubMed]","DOI":"10.3322\/caac.20107"},{"key":"2","doi-asserted-by":"crossref","unstructured":"Ullah MF and Aatif M. The footprints of cancer development: Cancer biomarkers. Cancer Treat Rev. 2009; 35(3):193-200. [PubMed]","DOI":"10.1016\/j.ctrv.2008.10.004"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Zaridze DG. Molecular epidemiology of cancer. Biochemistry. 2008; 73(5):532-542. [PubMed]","DOI":"10.1134\/S0006297908050064"},{"key":"4","doi-asserted-by":"crossref","unstructured":"He J, Shi TY, Zhu ML, Wang MY, Li QX and Wei QY. Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: a meta-analysis. Int J Cancer. 2013; 133(8):1765-1775. [PubMed]","DOI":"10.1002\/ijc.28089"},{"key":"5","doi-asserted-by":"crossref","unstructured":"Xue WQ, He YQ, Zhu JH, Ma JQ, He J and Jia WH. Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis. Sci Rep. 2014; 4:6791. [PubMed] https:\/\/doi.org\/10.1038\/srep06791.","DOI":"10.1038\/srep06791"},{"key":"6","doi-asserted-by":"crossref","unstructured":"Carlson CS, Eberle MA, Kruglyak L and Nickerson DA. Mapping complex disease loci in whole-genome association studies. Nature. 2004; 429(6990):446-452. [PubMed]","DOI":"10.1038\/nature02623"},{"key":"7","doi-asserted-by":"crossref","unstructured":"Manolio TA. Genomewide association studies and assessment of the risk of disease. N Engl J Med. 2010; 363(2):166-176. [PubMed]","DOI":"10.1056\/NEJMra0905980"},{"key":"8","doi-asserted-by":"crossref","unstructured":"Sakamoto H, Yoshimura K, Saeki N, Katai H, Shimoda T, Matsuno Y, Saito D, Sugimura H, Tanioka F, Kato S, Matsukura N, Matsuda N, Nakamura T, Hyodo I, Nishina T, Yasui W, et al. Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet. 2008; 40(6):730-740.[PubMed]","DOI":"10.1038\/ng.152"},{"key":"9","doi-asserted-by":"crossref","unstructured":"Wu X, Ye Y, Kiemeney LA, Sulem P, Rafnar T, Matullo G, Seminara D, Yoshida T, Saeki N, Andrew AS, Dinney CP, Czerniak B, Zhang ZF, Kiltie AE, Bishop DT, Vineis P, et al. Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet. 2009; 41(9):991-995. [PubMed] https:\/\/doi.org\/10.1038\/ng.421.","DOI":"10.1038\/ng.421"},{"key":"10","doi-asserted-by":"crossref","unstructured":"Reiter RE, Gu Z, Watabe T, Thomas G, Szigeti K, Davis E, Wahl M, Nisitani S, Yamashiro J, Le Beau MM, Loda M and Witte ON. Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. Proc Natl Acad Sci U S A. 1998; 95(4):1735-1740.[PubMed] https:\/\/doi.org\/10.1073\/pnas.95.4.1735.","DOI":"10.1073\/pnas.95.4.1735"},{"key":"11","doi-asserted-by":"crossref","unstructured":"Eshel R, Zanin A, Kapon D, Sagi-Assif O, Brakenhoff R, van Dongen G and Witz IP. Human Ly-6 antigen E48 (Ly6D) regulates important interaction parameters between endothelial cells and head-and-neck squamous carcinoma cells. Int J Cancer. 2002; 98(6):803-810. [PubMed]","DOI":"10.1002\/ijc.10301"},{"key":"12","doi-asserted-by":"crossref","unstructured":"Saeki N, Gu J, Yoshida T and Wu X. Prostate stem cell antigen: a Jekyll and Hyde molecule? Clin Cancer Res. 2010; 16(14):3533-3538.. 2002; 98(6):803-810. [PubMed] https:\/\/doi.org\/10.1158\/1078-0432.CCR-09-3169.","DOI":"10.1158\/1078-0432.CCR-09-3169"},{"key":"13","doi-asserted-by":"crossref","unstructured":"Bahrenberg G, Brauers A, Joost HG and Jakse G. Reduced expression of PSCA, a member of the LY-6 family of cell surface antigens, in bladder, esophagus, and stomach tumors. Biochem Biophys Res Commun. 2000; 275(3):783788. [PubMed]","DOI":"10.1006\/bbrc.2000.3393"},{"key":"14","doi-asserted-by":"crossref","unstructured":"Matsuo K, Tajima K, Suzuki T, Kawase T, Watanabe M, Shitara K, Misawa K, Ito S, Sawaki A, Muro K, Nakamura T, Yamao K, Yamamura Y, Hamajima N, Hiraki A and Tanaka H. Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese. Int J Cancer. 2009; 125(8):1961-1964.[PubMed]","DOI":"10.1002\/ijc.24519"},{"key":"15","doi-asserted-by":"crossref","unstructured":"Wu C, Wang G, Yang M, Huang L, Yu D, Tan W and Lin D. Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population. Mol Carcinog. 2009; 48(12):1131-1138. [PubMed]","DOI":"10.1002\/mc.20565"},{"key":"16","doi-asserted-by":"crossref","unstructured":"Lu Y, Chen J, Ding Y, Jin G, Wu J, Huang H, Deng B, Hua Z, Zhou Y, Shu Y, Liu P, Hu Z, Shen J, Xu Y and Shen H. Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-type gastric cancer in a Chinese population. Int J Cancer. 2010; 127(9):2183-2189. [PubMed]","DOI":"10.1002\/ijc.25228"},{"key":"17","doi-asserted-by":"crossref","unstructured":"Ou J, Li K, Ren H, Bai H, Zeng D and Zhang C. Association and haplotype analysis of prostate stem cell antigen with gastric cancer in Tibetans. DNA Cell Biol. 2010; 29(6):319323. [PubMed]","DOI":"10.1089\/dna.2009.0960"},{"key":"18","doi-asserted-by":"crossref","unstructured":"Wang S, Tang J, Wang M, Yuan L and Zhang Z. Genetic variation in PSCA and bladder cancer susceptibility in a Chinese population. Carcinogenesis. 2010; 31(4):621-624. [PubMed]","DOI":"10.1093\/carcin\/bgp323"},{"key":"19","doi-asserted-by":"crossref","unstructured":"Joung JY, Lee YS, Park S, Yoon H, Lee SJ, Park WS, Seo HK, Chung J, Kim SY, Hong SH, Kim JS and Lee KH. Haplotype analysis of prostate stem cell antigen and association with prostate cancer risk. J Urol. 2011; 185(6):2112-2118. [PubMed]","DOI":"10.1016\/j.juro.2011.01.083"},{"key":"20","doi-asserted-by":"crossref","unstructured":"Lochhead P, Frank B, Hold GL, Rabkin CS, Ng MT, Vaughan TL, Risch HA, Gammon MD, Lissowska J, Weck MN, Raum E, Muller H, Illig T, Klopp N, Dawson A, McColl KE, et al. Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals. Gastroenterology. 2011; 140(2):435-441. [PubMed] https:\/\/doi.org\/10.1053\/j.gastro.2010.11.001.","DOI":"10.1053\/j.gastro.2010.11.001"},{"key":"21","doi-asserted-by":"crossref","unstructured":"Song HR, Kim HN, Piao JM, Kweon SS, Choi JS, Bae WK, Chung IJ, Park YK, Kim SH, Choi YD and Shin MH. Association of a common genetic variant in prostate stemcell antigen with gastric cancer susceptibility in a Korean population. Mol Carcinog. 2011; 50(11):871-875.","DOI":"10.1002\/mc.20796"},{"key":"22","doi-asserted-by":"crossref","unstructured":"Zeng Z, Wu X, Chen F, Yu J, Xue L, Hao Y, Wang Y, Chen M, Sung JJ and Hu P. Polymorphisms in prostate stem cell antigen gene rs2294008 increase gastric cancer risk in Chinese. Mol Carcinog. 2011; 50(5):353-358. [PubMed]","DOI":"10.1002\/mc.20718"},{"key":"23","doi-asserted-by":"crossref","unstructured":"Fu YP, Kohaar I, Rothman N, Earl J, Figueroa JD, Ye Y, Malats N, Tang W, Liu L, Garcia-Closas M, Muchmore B, Chatterjee N, Tarway M, Kogevinas M, Porter-Gill P, Baris D, et al. Common genetic variants in the PSCA gene influence gene expression and bladder cancer risk. Proc Natl Acad Sci U S A. 2012; 109(13):4974-4979. [PubMed] https:\/\/doi.org\/10.1073\/pnas.1202189109.","DOI":"10.1073\/pnas.1202189109"},{"key":"24","doi-asserted-by":"crossref","unstructured":"Kim SY, Yoo JY, Shin A, Kim Y, Lee ES and Lee YS. Prostate stem cell antigen single nucleotide polymorphisms influence risk of estrogen receptor negative breast cancer in Korean females. Asian Pac J Cancer Prev. 2012; 13(1):4148. [PubMed]","DOI":"10.7314\/APJCP.2012.13.1.041"},{"key":"25","doi-asserted-by":"crossref","unstructured":"Li F, Zhong MZ, Li JH, Liu W and Li B. Case-control study of single nucleotide polymorphisms of PSCA and MUC1 genes with gastric cancer in a Chinese. Asian Pac J Cancer Prev. 2012; 13(6):2593-2596. [PubMed]","DOI":"10.7314\/APJCP.2012.13.6.2593"},{"key":"26","doi-asserted-by":"crossref","unstructured":"Sala N, Munoz X, Travier N, Agudo A, Duell EJ, Moreno V, Overvad K, Tjonneland A, Boutron-Ruault MC, ClavelChapelon F, Canzian F, Kaaks R, Boeing H, Meidtner K, Trichopoulos A, Tsiotas K, et al. Prostate stem-cell antigen gene is associated with diffuse and intestinal gastric cancer in Caucasians: results from the EPIC-EURGAST study. Int J Cancer. 2012; 130(10):2417-2427. [PubMed]","DOI":"10.1002\/ijc.26243"},{"key":"27","doi-asserted-by":"crossref","unstructured":"Smith C, Lochhead P, Basavaraju U, Hold GL, Fyfe N, Murray GI and El-Omar EM. Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study. BMC Res Notes. 2012; 5:371. [PubMed] https:\/\/doi.org\/10.1186\/1756-0500-5-371.","DOI":"10.1186\/1756-0500-5-371"},{"key":"28","doi-asserted-by":"crossref","unstructured":"Ma Z, Hu Q, Chen Z, Tao S, Macnamara L, Kim ST, Tian L, Xu K, Ding Q, Zheng SL, Sun J, Xia G and Xu J. Systematic evaluation of bladder cancer risk-associated single-nucleotide polymorphisms in a Chinese population. Mol Carcinog. 2013; 52(11):916-921. [PubMed]","DOI":"10.1002\/mc.21932"},{"key":"29","doi-asserted-by":"crossref","unstructured":"Ono H, Chihara D, Chiwaki F, Yanagihara K, Sasaki H, Sakamoto H, Tanaka H, Yoshida T, Saeki N and Matsuo K. Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells. J Carcinog. 2013; 12:4. [PubMed] https:\/\/doi.org\/10.4103\/1477-3163.109030.","DOI":"10.4103\/1477-3163.109030"},{"key":"30","doi-asserted-by":"crossref","unstructured":"Rai R, Sharma KL, Misra S, Kumar A and Mittal B. PSCA gene variants (rs2294008 and rs2978974) confer increased susceptibility of gallbladder carcinoma in females. Gene. 2013; 530(2):172-177. [PubMed]","DOI":"10.1016\/j.gene.2013.08.058"},{"key":"31","doi-asserted-by":"crossref","unstructured":"Rizzato C, Kato I, Plummer M, Munoz N and Canzian F. Genetic variation in PSCA and risk of gastric advanced preneoplastic lesions and cancer in relation to Helicobacter pylori infection. PloS One. 2013; 8(9):e73100. [PubMed] https:\/\/doi.org\/10.1371\/journal.pone.0073100.","DOI":"10.1371\/journal.pone.0073100"},{"key":"32","doi-asserted-by":"crossref","unstructured":"Zhao J, Geng P, Li Z, Cui S, Wang L, Li J, Ji F, Li G, Shen G, Lin M and Shen C. Prostate stem cell antigen rs2294008 polymorphism differentially contributes to -negative gastric cancer among various populations in China. Mol Clin Oncol. 2013; 1(3):493-498.[PubMed] https:\/\/doi.org\/10.3892\/mco.2013.70.","DOI":"10.3892\/mco.2013.70"},{"key":"33","doi-asserted-by":"crossref","unstructured":"Dai N, Zheng M, Wang C, Ji Y, Du J, Zhu C, He Y, Zhu M, Zhu X, Sun M, Dai J, Ma H, Chen J, Hu Z, Gu H, Jin G, et al. Genetic variants at 8q24 are associated with risk of esophageal squamous cell carcinoma in a Chinese population. Cancer Sci. 2014; 105(6):731-735. [PubMed] https:\/\/doi.org\/10.1111\/cas.12399.","DOI":"10.1111\/cas.12399"},{"key":"34","doi-asserted-by":"crossref","unstructured":"Sun Y, Gu J, Ajani JA, Chang DW, Wu X and Stroehlein JR. Genetic and intermediate phenotypic susceptibility markers of gastric cancer in Hispanic Americans: A case-control study. Cancer. 2014; 120(19):3040-3048. [PubMed]","DOI":"10.1002\/cncr.28792"},{"key":"35","doi-asserted-by":"crossref","unstructured":"Wang P, Ye D, Guo J, Liu F, Jiang H, Gong J, Gu C, Shao Q, Sun J, Zheng SL, Yu H, Lin X, Xia G, Fang Z, Zhu Y, Ding Q, et al. Genetic score of multiple risk-associated single nucleotide polymorphisms is a marker for genetic susceptibility to bladder cancer. Genes Chromosomes Cancer. 2014; 53(1):98-105. [PubMed]","DOI":"10.1002\/gcc.22121"},{"key":"36","unstructured":"Ju YF, Diao YQ, Song MQ and Jiang XJ. [PSCA polymorphism rs2976392 in gastric cancer]. Chinese Journal of Oncology Prevention and Treatment. 2013; 5(4):300-303."},{"key":"37","unstructured":"Shen G, Zhang C, Zhao J, Geng P, Dou L, Zhang S, Ma D and Li G. [A study of relationship between PSCA gene polymorphisms and susceptibility to Tibetan gastric cancer in Qinghai area]. Journal of Qinghai Medical College. 2011; 32(3):169-171."},{"key":"38","unstructured":"Wang B, Pang C, Yang G, Ren J, Wang H and Wang Y. [An association study of SNP rs2976392 in PSCA gene and gastric cancer]. Journal of Baotou Medical College. 2014; 30(4):1-2."},{"key":"39","unstructured":"Kupcinskas J, Wex T, Link A, Bartuseviciute R, Dedelaite M, Kevalaite G, Leja M, Skieceviciene J, Kiudelis G, Jonaitis L, Kupcinskas L and Malfertheiner P. PSCA and MUC1 gene polymorphisms are linked with gastric cancer and pre-malignant gastric conditions. Anticancer Res. 2014; 34(12):7167-7175. [PubMed]"},{"key":"40","doi-asserted-by":"crossref","unstructured":"Lee JH, Song HR, Kim HN, Kweon SS, Yun YW, Choi JS, Jung SI, Kwon DD, Kim SH, Choi YD and Shin MH. Genetic variation in PSCA is associated with bladder cancer susceptibility in a Korean population. Asian Pac J Cancer Prev. 2014; 15(20):8901-8904. [PubMed]","DOI":"10.7314\/APJCP.2014.15.20.8901"},{"key":"41","doi-asserted-by":"crossref","unstructured":"Garcia-Gonzalez MA, Bujanda L, Quintero E, Santolaria S, Benito R, Strunk M, Sopena F, Thomson C, Perez-Aisa A, Nicolas-Perez D, Hijona E, Carrera-Lasfuentes P, Piazuelo E, Jimenez P, Espinel J, Campo R, et al. Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease. Int J Cancer. 2015. DOI: 10.1002\/ijc.29500 [PubMed] https:\/\/doi.org\/10.1002\/ijc.29500.","DOI":"10.1002\/ijc.29500"},{"key":"42","doi-asserted-by":"crossref","unstructured":"Ichikawa H, Sugimoto M, Uotani T, Sahara S, Yamade M, Iwaizumi M, Yamada T, Osawa S, Sugimoto K, Miyajima H, Yamaoka Y and Furuta T. Influence of Prostate Stem Cell Antigen Gene Polymorphisms on Susceptibility to Helicobacter pylori-associated Diseases: A Case-control Study. Helicobacter. 2015; 20(2):106-113. [PubMed]","DOI":"10.1111\/hel.12183"},{"key":"43","doi-asserted-by":"crossref","unstructured":"Sun H, Wu X, Wu F, Li Y, Yu Z, Chen X, Chen Y and Yang W. Associations of genetic variants in the PSCA, MUC1 and PLCE1 genes with stomach cancer susceptibility in a Chinese population. PloS One. 2015; 10(2):e0117576. [PubMed] https:\/\/doi.org\/10.1371\/journal.pone.0117576.","DOI":"10.1371\/journal.pone.0117576"},{"key":"44","doi-asserted-by":"crossref","unstructured":"Qiao L and Feng Y. Genetic variations of prostate stem cell antigen (PSCA) contribute to the risk of gastric cancer for Eastern Asians: a meta-analysis based on 16792 individuals. Gene. 2012; 493(1):83-91. [PubMed]","DOI":"10.1016\/j.gene.2011.11.017"},{"key":"45","doi-asserted-by":"crossref","unstructured":"Shi D, Wang S, Gu D, Wu D, Wang M, Chu H, Tong N, Ma L, Zhong D and Zhang Z. The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis. J Cancer Res Clin Oncol. 2012; 138(8):1339-1345. [PubMed]","DOI":"10.1007\/s00432-012-1210-6"},{"key":"46","doi-asserted-by":"crossref","unstructured":"Wang T, Zhang L, Li H, Wang B and Chen K. Prostate stem cell antigen polymorphisms and susceptibility to gastric cancer: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2012; 21(5):843-850. [PubMed]","DOI":"10.1158\/1055-9965.EPI-11-1176"},{"key":"47","doi-asserted-by":"crossref","unstructured":"Zhang QH, Yao YL, Gu T, Gu JH, Chen L and Liu Y. Association of the PSCA rs2294008 C>T polymorphism with gastric cancer risk: evidence from a meta-analysis. Asian Pac J Cancer Prev. 2012; 13(6):2867-2871. [PubMed]","DOI":"10.7314\/APJCP.2012.13.6.2867"},{"key":"48","doi-asserted-by":"crossref","unstructured":"Zhang T, Chen YN, Wang Z, Chen JQ and Huang S. Effect of PSCA gene polymorphisms on gastric cancer risk and survival prediction: A meta-analysis. Exp Ther Med. 2012; 4(1):158-164. [PubMed] https:\/\/doi.org\/10.3892\/etm.2012.563.","DOI":"10.3892\/etm.2012.563"},{"key":"49","doi-asserted-by":"crossref","unstructured":"Gu X, Zhang W, Xu L and Cai D. Quantitative assessment of the influence of prostate stem cell antigen polymorphisms on gastric cancer risk. Tumour Biol. 2014; 35(3):21672174. [PubMed]","DOI":"10.1007\/s13277-013-1287-9"},{"key":"50","doi-asserted-by":"crossref","unstructured":"Zhao Y, Gui ZL, Liao S, Gao F, Ge YZ and Jia RP. Prostate stem cell antigen rs2294008 (C>T) polymorphism and bladder cancer risk: a meta-analysis based on cases and controls. Genet Mol Res. 2014; 13(3):5534-5540. [PubMed]","DOI":"10.4238\/2014.July.25.7"},{"key":"51","doi-asserted-by":"crossref","unstructured":"Wang M, Bai J, Tan Y, Wang S, Tian Y, Gong W, Zhou Y, Gao Y, Zhou J and Zhang Z. Genetic variant in PSCA predicts survival of diffuse-type gastric cancer in a Chinese population. Int J Cancer. 2011; 129(5):1207-1213. [PubMed]","DOI":"10.1002\/ijc.25740"},{"key":"52","doi-asserted-by":"crossref","unstructured":"Abnet CC, Freedman ND, Hu N, Wang Z, Yu K, Shu XO, Yuan JM, Zheng W, Dawsey SM, Dong LM, Lee MP, Ding T, Qiao YL, Gao YT, Koh WP, Xiang YB, et al. A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet. 2010; 42(9):764-767. [PubMed] https:\/\/doi.org\/10.1038\/ng.649.","DOI":"10.1038\/ng.649"},{"key":"53","doi-asserted-by":"crossref","unstructured":"Shi Y, Hu Z, Wu C, Dai J, Li H, Dong J, Wang M, Miao X, Zhou Y, Lu F, Zhang H, Hu L, Jiang Y, Li Z, Chu M, Ma H, et al. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nat Genet. 2011; 43(12):1215-1218. [PubMed]","DOI":"10.1038\/ng.978"},{"key":"54","doi-asserted-by":"crossref","unstructured":"Hwang JY, Kim DH, Ji YI, Jin Go M, Heo L, Jin Kim Y, Sung Sohn T, Hyung Noh J, Kim S, Lee YS, Kim SY, Kim YW, Won Ryu K, Choi IJ, Lee J, Kim BJ, et al. Recapitulation of previous genome-wide association studies with two distinct pathophysiological entities of gastric cancer in the Korean population. J Hum Genet. 2013; 58(4):233-235. [PubMed]","DOI":"10.1038\/jhg.2012.158"},{"key":"55","doi-asserted-by":"crossref","unstructured":"Tanikawa C, Urabe Y, Matsuo K, Kubo M, Takahashi A, Ito H, Tajima K, Kamatani N, Nakamura Y and Matsuda K. A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. Nat Genet. 2012; 44(4):430-434, S431-432. [PubMed]","DOI":"10.1038\/ng.1109"},{"key":"56","doi-asserted-by":"crossref","unstructured":"Yuan LJ, Jin TB, Yin JK, Du XL, Wang Q, Dong R, Wang SZ, Cui Y, Chen C and Lu JG. Polymorphisms of tumor-related genes IL-10, PSCA, MTRR and NOC3L are associated with the risk of gastric cancer in the Chinese Han population. Cancer Epidemiol. 2012; 36(6):e366-372. [PubMed]","DOI":"10.1016\/j.canep.2012.05.016"},{"key":"57","doi-asserted-by":"crossref","unstructured":"Wang N, Wang L, Yang H, Zhang HQ, Lan B, He X, Jin TB, Kang LL and Chen C. Multiple genetic variants are associated with colorectal cancer risk in the Han Chinese population. Eur J Cancer Prev. 2015; 24(1):1-5. [PubMed]","DOI":"10.1097\/CEJ.0000000000000012"},{"key":"58","doi-asserted-by":"crossref","unstructured":"Krejs GJ. Gastric cancer: epidemiology and risk factors. Dig Dis. 2010; 28(4-5):600-603. [PubMed]","DOI":"10.1159\/000320277"},{"key":"59","doi-asserted-by":"crossref","unstructured":"He J, Liao XY, Zhu JH, Xue WQ, Shen GP, Huang SY, Chen W and Jia WH. Association of MTHFR C677T and A1298C polymorphisms with non-Hodgkin lymphoma susceptibility: evidence from a meta-analysis. Sci Rep. 2014; 4:6159. [PubMed] https:\/\/doi.org\/10.1038\/srep06159.","DOI":"10.1038\/srep06159"},{"key":"60","doi-asserted-by":"crossref","unstructured":"Hua RX, Li HP, Liang YB, Zhu JH, Zhang B, Ye S, Dai QS, Xiong SQ, Gu Y and Sun XZ. Association between the PARP1 Val762Ala polymorphism and cancer risk: evidence from 43 studies. PloS One. 2014; 9(1):e87057. [PubMed] https:\/\/doi.org\/10.1371\/journal.pone.0087057.","DOI":"10.1371\/journal.pone.0087057"},{"key":"61","unstructured":"Mantel N and Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959; 22(4):719-748. [PubMed]"},{"key":"62","doi-asserted-by":"crossref","unstructured":"DerSimonian R and Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986; 7(3):177-188.[PubMed] https:\/\/doi.org\/10.18632\/oncotarget.26908.","DOI":"10.18632\/oncotarget.26908"},{"key":"63","doi-asserted-by":"crossref","unstructured":"Egger M, Davey Smith G, Schneider M and Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997; 315(7109):629-634. [PubMed] https:\/\/doi.org\/10.1136\/bmj.315.7109.629.","DOI":"10.1136\/bmj.315.7109.629"}],"container-title":["Genes &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.genesandcancer.com\/lookup\/doi\/10.18632\/genesandcancer.63","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T14:04:17Z","timestamp":1598796257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.genesandcancer.com\/lookup\/doi\/10.18632\/genesandcancer.63"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,4]]},"references-count":63,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["63","26124924"],"URL":"https:\/\/doi.org\/10.18632\/genesandcancer.63","relation":{},"ISSN":["1947-6027"],"issn-type":[{"value":"1947-6027","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,4]]}}}