{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:45:13Z","timestamp":1778561113913,"version":"3.51.4"},"reference-count":40,"publisher":"Impact Journals, LLC","issue":"29","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,7,18]]},"DOI":"10.18632\/oncotarget.11603","type":"journal-article","created":{"date-parts":[[2016,8,25]],"date-time":"2016-08-25T16:53:49Z","timestamp":1472144029000},"page":"46834-46845","source":"Crossref","is-referenced-by-count":43,"title":["Distinct plasma lipids profiles of recurrent ovarian cancer by liquid chromatography-mass spectrometry"],"prefix":"10.18632","volume":"8","author":[{"given":"Junnan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinlong","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Gynecology Oncology, The Affiliated Tumor Hospital of Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingtao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjie","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenzi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harman S.","family":"Dhillon","sequence":"additional","affiliation":[{"name":"Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita S.","family":"Openkova","sequence":"additional","affiliation":[{"name":"Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Washington, Seattle 96596, WA, U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Harbin Medical University, Harbin 150086, P.R. China"},{"name":"Key Laboratory of Cardiovascular Medicine Research (Harbin Medical University), Ministry of Education, Harbin 150086, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2016,8,25]]},"reference":[{"key":"1","first-page":"15","article-title":"Ovarian cancer screening and early detection in the general population","volume":"4","author":"Olawaiye","year":"2011","journal-title":"Reviews in Obstetrics and Gynecology"},{"key":"2","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/jnci\/djg036","article-title":"A randomized clinical trial of cisplatin\/paclitaxel versus carboplatin\/paclitaxel as first-line treatment of ovarian cancer","volume":"95","author":"Schr\u00f6der","year":"2003","journal-title":"Journal of the National Cancer Institute"},{"key":"3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199601043340101","article-title":"Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer","volume":"334","author":"Davidson","year":"1996","journal-title":"The New England Journal Of Medicine"},{"key":"4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.critrevonc.2013.08.017","article-title":"Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer","volume":"89","author":"Ray-Coquard","year":"2014","journal-title":"Critical reviews in oncology\/hematology"},{"key":"5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0889-8545(21)00314-4","article-title":"Secondary cytoreductive surgery for ovarian cancer","volume":"21","author":"Morris","year":"1994","journal-title":"Obstetrics and gynecology clinics of North America"},{"key":"6","first-page":"156","article-title":"Stages III and IV invasive epithelial ovarian carcinoma in younger versus older women: what prognostic factors are important?","volume":"102","author":"DiSaia","year":"2003","journal-title":"Obstetrics and Gynecology"},{"key":"7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1006\/gyno.1993.1113","article-title":"Impact of age on survival of patients with ovarian cancer","volume":"49","author":"Almadrones","year":"1993","journal-title":"Gynecologic oncology"},{"key":"8","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1200\/JCO.2006.10.2517","article-title":"Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study","volume":"25","author":"McGuire","year":"2007","journal-title":"Journal of Clinical Oncology"},{"key":"9","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1007\/s00432-013-1435-z","article-title":"Prognostic significance of several biomarkers in epithelial ovarian cancer: a meta-analysis of published studies","volume":"139","author":"Wang","year":"2013","journal-title":"Journal of cancer research and clinical oncology"},{"key":"10","doi-asserted-by":"crossref","first-page":"973","DOI":"10.4161\/cbt.25966","article-title":"p19INK4d mRNA and protein expression as new prognostic factors in ovarian cancer patients","volume":"14","author":"Kupryjanczyk","year":"2013","journal-title":"Cancer biology & therapy"},{"key":"11","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1194\/jlr.D048801","article-title":"Highly automated nano-LC\/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols","volume":"55","author":"Lundanes","year":"2014","journal-title":"The Journal of lipid research"},{"key":"12","doi-asserted-by":"crossref","first-page":"8917","DOI":"10.1021\/ac302154g","article-title":"Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines","volume":"84","author":"Reid","year":"2012","journal-title":"Analytical chemistry"},{"key":"13","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1002\/elps.201200629","article-title":"Serum lipid profiling of patients with chronic hepatitis B, cirrhosis, and hepatocellular carcinoma by ultra fast LC\/IT-TOF MS","volume":"34","author":"Xu","year":"2013","journal-title":"Electrophoresis"},{"key":"14","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1752-0509-4-126","article-title":"Determining and interpreting correlations in lipidomic networks found in glioblastoma cells","volume":"4","author":"Conrad","year":"2010","journal-title":"BMC systems biology"},{"key":"15","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00216-010-4290-7","article-title":"Shotgun lipidomics for candidate biomarkers of urinary phospholipids in prostate cancer","volume":"399","author":"Moon","year":"2011","journal-title":"Analytical and bioanalytical chemistry"},{"key":"16","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/ijc.29010","article-title":"Large-scale profiling of metabolic dysregulation in ovarian cancer","volume":"136","author":"Lou","year":"2015","journal-title":"International Journal of Cancer"},{"key":"17","first-page":"1","article-title":"Differential plasma lipids profiling and lipid signatures as biomarkers in the early diagnosis of ovarian carcinoma using UPLC-MS","volume":"12","author":"Li","year":"2016","journal-title":"Metabolomics"},{"key":"18","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jchromb.2014.01.057","article-title":"Metabolic profiling study of early and late recurrence of hepatocellular carcinoma based on liquid chromatography-mass spectrometry","volume":"966","author":"Xu","year":"2014","journal-title":"Journal of Chromatography B"},{"key":"19","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.chroma.2013.10.002","article-title":"Searching for urine biomarkers of bladder cancer recurrence using a liquid chromatography-mass spectrometry and capillary electrophoresis\u2013mass spectrometry metabolomics approach","volume":"1318","author":"Barbas","year":"2013","journal-title":"Journal of Chromatography A"},{"key":"20","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1158\/1055-9965.EPI-14-0458","article-title":"Serum lipid profile and risk of prostate cancer recurrence: results from the SEARCH Database","volume":"23","author":"Freedland","year":"2014","journal-title":"Cancer Epidemiology Biomarkers & Prevention"},{"key":"21","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1212\/WNL.0000000000001093","article-title":"Metabolomics predicts stroke recurrence after transient ischemic attack","volume":"84","author":"Portero-Ot\u00edn","year":"2015","journal-title":"Neurology"},{"key":"22","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1039\/C4MB00407H","article-title":"Prediction of advanced ovarian cancer recurrence by plasma metabolic profiling","volume":"11","author":"Zhang","year":"2015","journal-title":"Molecular BioSystems"},{"key":"23","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1242\/dmm.011338","article-title":"Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development","volume":"6","author":"Schulze","year":"2013","journal-title":"Disease Models and Mechanisms"},{"key":"24","first-page":"1627","article-title":"Recurrence season impacts the survival of epithelial ovarian cancer patients","volume":"15","author":"Wu","year":"2013","journal-title":"Asian Pacific journal of cancer prevention: APJCP"},{"key":"25","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ygyno.2015.01.539","article-title":"Assessment of published models and prognostic variables in epithelial ovarian cancer at Mayo Clinic","volume":"137","author":"Tarabishy","year":"2015","journal-title":"Gynecologic oncology"},{"key":"26","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.bcp.2006.11.010","article-title":"Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor","volume":"73","author":"Bae","year":"2007","journal-title":"Biochemical pharmacology"},{"key":"27","doi-asserted-by":"crossref","first-page":"e41456","DOI":"10.1371\/journal.pone.0041456","article-title":"Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes","volume":"7","author":"Bruce","year":"2012","journal-title":"PLoS One"},{"key":"28","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.ccr.2009.03.027","article-title":"Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases","volume":"15","author":"Murrow","year":"2009","journal-title":"Cancer cell"},{"key":"29","first-page":"1","article-title":"Autotaxin expression and its connection with the TNF-alpha-NF-\u03baB axis in human hepatocellular carcinoma","volume":"9","author":"Maluccio","year":"2010","journal-title":"Molecular cancer"},{"key":"30","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1158\/0008-5472.CAN-09-3833","article-title":"Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells","volume":"70","author":"Mezzanzanica","year":"2010","journal-title":"Cancer research"},{"key":"31","doi-asserted-by":"crossref","unstructured":"Oskouian, Saba. Cancer treatment strategies targeting sphingolipid metabolism. Sphingolipids as Signaling and Regulatory Molecules: Springer; pp. 185\u2013205.","DOI":"10.1007\/978-1-4419-6741-1_13"},{"key":"32","doi-asserted-by":"crossref","first-page":"6352","DOI":"10.1158\/0008-5472.CAN-14-1292","article-title":"Ceramide kinase promotes tumor cell survival and mammary tumor recurrence","volume":"74","author":"Chodosh","year":"2014","journal-title":"Cancer research"},{"key":"33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1042\/BJ20130644","article-title":"Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle","volume":"455","author":"Dequiedt","year":"2013","journal-title":"Biochemical Journal"},{"key":"34","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5732\/cjc.014.10289","article-title":"The PI3K\/Akt\/mTOR pathway in ovarian cancer: therapeutic opportunities and challenges","volume":"34","author":"Leary","year":"2015","journal-title":"Chinese journal of cancer"},{"key":"35","first-page":"275","article-title":"The PI3K\/Akt\/mTOR Pathway in Ovarian Cancer: Biological Rationale and Therapeutic Opportunities","author":"Lhomm\u00e9","year":"2013","journal-title":"Ovarian cancer-a clinical and translational update Croatia: InTech"},{"key":"36","unstructured":"Hu, Zhang, Song. Lipid metabolism, metabolic syndrome, and cancer. INTECH Open Access Publisher."},{"key":"37","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1002\/ijc.25703","article-title":"Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort study","volume":"128","author":"Zheng","year":"2011","journal-title":"International Journal of Cancer"},{"key":"38","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1158\/1055-9965.EPI-09-0291","article-title":"Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal women","volume":"18","author":"Deapen","year":"2009","journal-title":"Cancer Epidemiology Biomarkers & Prevention"},{"key":"39","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1053\/j.ajkd.2004.03.024","article-title":"The effect of n-3 fatty acids on plasma lipids and lipoproteins and blood pressure in patients with CRF","volume":"44","author":"Schmidt","year":"2004","journal-title":"American journal of kidney diseases"},{"key":"40","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/ijc.28491","article-title":"Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients","volume":"134","author":"Denkert","year":"2014","journal-title":"International Journal of Cancer"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.11603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T02:02:18Z","timestamp":1718762538000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.11603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,25]]},"references-count":40,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2017,7,18]]}},"alternative-id":["11603","27564116"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.11603","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,25]]}}}