{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:33:32Z","timestamp":1790609612314,"version":"4.1.0"},"reference-count":27,"publisher":"Impact Journals, LLC","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,1,10]]},"DOI":"10.18632\/oncotarget.12446","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T21:22:53Z","timestamp":1475616173000},"page":"2525-2535","source":"Crossref","is-referenced-by-count":27,"title":["MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer"],"prefix":"10.18632","volume":"8","author":[{"given":"Xi","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailiu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longwei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongwang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuerui","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laiping","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial - Head & Neck Oncology, Shanghai Key Laboratory of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"1","first-page":"69","article-title":"Global cancer statistics","volume":"61","author":"Forman","year":"2011","journal-title":"CA: a cancer journal for clinicians"},{"key":"2","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.oraloncology.2015.08.009","article-title":"Elective versus therapeutic neck dissection in node-negative oral cancer: Evidence from five randomized controlled trials","volume":"51","author":"Zhang","year":"2015","journal-title":"Oral Oncol"},{"key":"3","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/j.jcms.2014.04.012","article-title":"Anterolateral thigh myocutaneous flaps as the preferred flaps for reconstruction of oral and maxillofacial defects","volume":"42","author":"Gong","year":"2014","journal-title":"J Craniomaxillofac Surg"},{"key":"4","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.joms.2014.09.021","article-title":"Transfer of anterolateral thigh flaps in elderly oral cancer patients: complications in oral and maxillofacial reconstruction","volume":"73","author":"Zhang","year":"2015","journal-title":"J Oral Maxillofac Surg"},{"key":"5","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/lary.24840","article-title":"The role of elective neck dissection in early stage buccal cancer","volume":"125","author":"Chen","year":"2015","journal-title":"Laryngoscope"},{"key":"6","doi-asserted-by":"crossref","first-page":"e0132476","DOI":"10.1371\/journal.pone.0132476","article-title":"The Harmonic Scalpel versus Conventional Hemostasis for Neck Dissection: A Meta-Analysis of the Randomized Controlled Trials","volume":"10","author":"Zhang","year":"2015","journal-title":"PLoS One"},{"key":"7","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1002\/hed.21033","article-title":"Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma","volume":"31","author":"Trendell-Smith","year":"2009","journal-title":"Head Neck"},{"key":"8","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.oraloncology.2011.03.009","article-title":"A meta-analysis of the randomized controlled trials on elective neck dissection versus therapeutic neck dissection in oral cavity cancers with clinically node-negative neck","volume":"47","author":"Sesterhenn","year":"2011","journal-title":"Oral Oncol"},{"key":"9","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1056\/NEJMoa1506007","article-title":"Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer","volume":"373","author":"Ghosh-Laskar","year":"2015","journal-title":"N Engl J Med"},{"key":"10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1471-2407-9-11","article-title":"Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis","volume":"9","author":"Shaha","year":"2009","journal-title":"BMC Cancer"},{"key":"11","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1038\/sj.onc.1204685","article-title":"Oral cancer in vivo gene expression profiling assisted by laser capture microdissection and microarray analysis","volume":"20","author":"Todd","year":"2001","journal-title":"Oncogene"},{"key":"12","first-page":"1184","article-title":"Molecular classification of head and neck squamous cell carcinoma using cDNA microarrays","volume":"62","author":"Childs","year":"2002","journal-title":"Cancer Res"},{"key":"13","first-page":"1179","article-title":"Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma","volume":"63","author":"Hofele","year":"2003","journal-title":"Cancer Res"},{"key":"14","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1038\/sj.onc.1208285","article-title":"Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity","volume":"24","author":"Muschel","year":"2005","journal-title":"Oncogene"},{"key":"15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.canlet.2012.03.025","article-title":"Over-expression of MAGED4B increases cell migration and growth in oral squamous cell carcinoma and is associated with poor disease outcome","volume":"321","author":"Cheong","year":"2012","journal-title":"Cancer Lett"},{"key":"16","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/mc.22007","article-title":"Decreased expression of kallikrein-related peptidase 13: possible contribution to metastasis of human oral cancer","volume":"53","author":"Uzawa","year":"2014","journal-title":"Mol Carcinog"},{"key":"17","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1002\/oby.21103","article-title":"MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation","volume":"23","author":"Pulkkinen","year":"2015","journal-title":"Obesity (Silver Spring)"},{"key":"18","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ajpath.2011.10.016","article-title":"Differentiation-promoting culture of competent and noncompetent keratinocytes identifies biomarkers for head and neck cancer","volume":"180","author":"Grafstrom","year":"2012","journal-title":"Am J Pathol"},{"key":"19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nature04296","article-title":"Oncogenic pathway signatures in human cancers as a guide to targeted therapies","volume":"439","author":"Dressman","year":"2006","journal-title":"Nature"},{"key":"20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1136\/thoraxjnl-2014-205091","article-title":"A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD","volume":"70","author":"Hao","year":"2015","journal-title":"Thorax"},{"key":"21","doi-asserted-by":"crossref","first-page":"5092","DOI":"10.1038\/ncomms6092","article-title":"Calcium-dependent FAK\/CREB\/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential","volume":"5","author":"Mok","year":"2014","journal-title":"Nat Commun"},{"key":"22","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ccr.2009.10.018","article-title":"A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2","volume":"16","author":"Brady","year":"2009","journal-title":"Cancer Cell"},{"key":"23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.4161\/cam.4.2.11716","article-title":"A prognostic gene signature in advanced ovarian cancer reveals a microfibril-associated protein (MAGP2) as a promoter of tumor cell survival and angiogenesis","volume":"4","author":"Banyard","year":"2010","journal-title":"Cell Adh Migr"},{"key":"24","doi-asserted-by":"crossref","first-page":"34404","DOI":"10.1074\/jbc.M111.267211","article-title":"Functional characterization of TNNC1 rare variants identified in dilated cardiomyopathy","volume":"286","author":"Hershberger","year":"2011","journal-title":"J Biol Chem"},{"key":"25","doi-asserted-by":"crossref","first-page":"8038","DOI":"10.4238\/2015.July.17.12","article-title":"Screening of differentially-expressed genes in the muscles of rabbit breeds with expression profile chip","volume":"14","author":"Wu","year":"2015","journal-title":"Genet Mol Res"},{"key":"26","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1037\/a0039143","article-title":"Work-family conflict, cardiometabolic risk, and sleep duration in nursing employees","volume":"20","author":"Buxton","year":"2015","journal-title":"Journal of occupational health psychology"},{"key":"27","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1007\/s12035-015-9175-5","article-title":"Neurovascular Invasion and Histological Grade Serve as the Risk Factors of Cervical Lymph Node Metastases in Early Tongue Squamous Cell Carcinoma","volume":"53","author":"Li","year":"2016","journal-title":"Mol Neurobiol"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.12446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T13:31:15Z","timestamp":1589117475000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.12446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,4]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,1,10]]}},"alternative-id":["12446","27713166"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.12446","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,4]]}}}