{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T04:04:49Z","timestamp":1793851489069,"version":"4.6.1"},"reference-count":34,"publisher":"Impact Journals, LLC","issue":"47","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2016,11,22]]},"DOI":"10.18632\/oncotarget.12949","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T00:51:13Z","timestamp":1477615873000},"page":"76453-76463","source":"Crossref","is-referenced-by-count":31,"title":["The aberrant expression of microRNAs and correlations with T cell subsets in patients with immune thrombocytopenia"],"prefix":"10.18632","volume":"7","author":[{"given":"Lu","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingqiang","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanfang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"He","sequence":"additional","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoxin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Hematology, Qilu Hospital, Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2016,10,27]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1182\/blood-2008-07-162503","article-title":"Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group","volume":"113","author":"Imbach","year":"2009","journal-title":"Blood"},{"key":"2","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1038\/nm921","article-title":"T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura","volume":"9","author":"Wadenvik","year":"2003","journal-title":"Nature medicine"},{"key":"3","first-page":"1","article-title":"Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura","volume":"38","author":"Moore","year":"1951","journal-title":"The Journal of laboratory and clinical medicine"},{"key":"4","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/MOH.0b013e32833eaef3","article-title":"Recent progress in understanding the pathogenesis of immune thrombocytopenia","volume":"17","author":"Freedman","year":"2010","journal-title":"Current opinion in hematology"},{"key":"5","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1182\/blood.V87.10.4245.bloodjournal87104245","article-title":"Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity","volume":"87","author":"Freedman","year":"1996","journal-title":"Blood"},{"key":"6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.thromres.2006.09.008","article-title":"Reduced Cd4+Cd25+ T cells in patients with idiopathic thrombocytopenic purpura","volume":"120","author":"Shiku","year":"2007","journal-title":"Thrombosis research"},{"key":"7","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.3324\/haematol.2009.007823","article-title":"Elevated profile of Th17, Th1 and Tc1 cells in patients with immune thrombocytopenic purpura","volume":"94","author":"Hou","year":"2009","journal-title":"Haematologica"},{"key":"8","doi-asserted-by":"crossref","first-page":"e26522","DOI":"10.1371\/journal.pone.0026522","article-title":"Increased number of Tc17 and correlation with Th17 cells in patients with immune thrombocytopenia","volume":"6","author":"Hou","year":"2011","journal-title":"PloS one"},{"key":"9","doi-asserted-by":"crossref","first-page":"e51339","DOI":"10.1371\/journal.pone.0051339","article-title":"Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome","volume":"7","author":"Hou","year":"2012","journal-title":"PloS one"},{"key":"10","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/s10875-011-9540-8","article-title":"Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis","volume":"31","author":"Wang","year":"2011","journal-title":"Journal of clinical immunology"},{"key":"11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.humimm.2012.04.015","article-title":"Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia","volume":"73","author":"Hou","year":"2012","journal-title":"Human immunology"},{"key":"12","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1261\/rna.2146903","article-title":"New microRNAs from mouse and human","volume":"9","author":"Tuschl","year":"2003","journal-title":"Rna"},{"key":"13","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/nature02873","article-title":"Mechanisms of gene silencing by double-stranded RNA","volume":"431","author":"Tuschl","year":"2004","journal-title":"Nature"},{"key":"14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.semcancer.2008.01.005","article-title":"MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation","volume":"18","author":"Pivarcsi","year":"2008","journal-title":"Seminars in cancer biology"},{"key":"16","doi-asserted-by":"crossref","first-page":"R71","DOI":"10.1186\/gb-2005-6-8-r71","article-title":"MicroRNA profiling of the murine hematopoietic system","volume":"6","author":"Kosik","year":"2005","journal-title":"Genome biology"},{"key":"17","unstructured":"Lu, Chuan-fang, Min, Tian, Shuang, Na, Yuan-xin, Dao-xin. The aberrant expression of microRNA-181a, microRNA-146a, microRNA-326 and micro-142-3p in peripheral blood mononuclear cell of patients with immune thrombocytopeniain Chinese. Journal of Shandong University. 2013; pp. 55\u201360+66."},{"key":"18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/bjh.12213","article-title":"Reduced expression of MIR409-3p in primary immune thrombocytopenia","volume":"161","author":"Yang","year":"2013","journal-title":"British journal of haematology"},{"key":"19","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/art.24436","article-title":"MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins","volume":"60","author":"Shen","year":"2009","journal-title":"Arthritis and rheumatism"},{"key":"20","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1186\/ar2493","article-title":"Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients","volume":"10","author":"Chan","year":"2008","journal-title":"Arthritis research & therapy"},{"key":"21","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1002\/art.23429","article-title":"Expression of microRNA-146 in rheumatoid arthritis synovial tissue","volume":"58","author":"Asahara","year":"2008","journal-title":"Arthritis and rheumatism"},{"key":"22","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/nature06878","article-title":"TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function","volume":"453","author":"Littman","year":"2008","journal-title":"Nature"},{"key":"23","doi-asserted-by":"crossref","first-page":"e128","DOI":"10.1182\/blood-2010-06-292920","article-title":"MicroRNA expression in maturing murine megakaryocytes","volume":"116","author":"Weiss","year":"2010","journal-title":"Blood"},{"key":"24","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1038\/ni.1798","article-title":"MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis","volume":"10","author":"Pei","year":"2009","journal-title":"Nature immunology"},{"key":"25","doi-asserted-by":"crossref","first-page":"e1002128","DOI":"10.1371\/journal.pgen.1002128","article-title":"A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus","volume":"7","author":"Shen","year":"2011","journal-title":"PLoS genetics"},{"key":"26","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1002\/art.34505","article-title":"Decreased microRNA-142-3p\/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus","volume":"64","author":"Lu","year":"2012","journal-title":"Arthritis and rheumatism"},{"key":"27","doi-asserted-by":"crossref","first-page":"e7158","DOI":"10.1371\/journal.pone.0007158","article-title":"miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression","volume":"4","author":"Mennerich","year":"2009","journal-title":"PloS one"},{"key":"28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/eji.200939381","article-title":"Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells","volume":"40","author":"Reiner","year":"2010","journal-title":"European journal of immunology"},{"key":"29","doi-asserted-by":"crossref","first-page":"e610","DOI":"10.1371\/journal.pone.0000610","article-title":"MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?","volume":"2","author":"Pivarcsi","year":"2007","journal-title":"PloS one"},{"key":"30","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1177\/0961203307084158","article-title":"Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients","volume":"16","author":"Yin","year":"2007","journal-title":"Lupus"},{"key":"31","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.cell.2007.03.008","article-title":"miR-181a is an intrinsic modulator of T cell sensitivity and selection","volume":"129","author":"Chen","year":"2007","journal-title":"Cell"},{"key":"32","doi-asserted-by":"crossref","first-page":"4190","DOI":"10.1182\/blood-2010-08-302984","article-title":"The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia","volume":"117","author":"American Society of","year":"2011","journal-title":"Blood"},{"key":"33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1034\/j.1600-0609.2003.00076.x","article-title":"Mycophenolate mofetil (MMF) for the treatment of steroid-resistant idiopathic thrombocytopenic purpura","volume":"70","author":"Zhang","year":"2003","journal-title":"European journal of haematology"},{"key":"34","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.cell.2010.08.012","article-title":"Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses","volume":"142","author":"Rudensky","year":"2010","journal-title":"Cell"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.12949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T06:55:53Z","timestamp":1718866553000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.12949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,27]]},"references-count":34,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2016,11,22]]}},"alternative-id":["12949","27802180"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.12949","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,27]]}}}