{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:45:08Z","timestamp":1783651508751,"version":"3.55.0"},"reference-count":29,"publisher":"Impact Journals, LLC","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,1,31]]},"DOI":"10.18632\/oncotarget.14395","type":"journal-article","created":{"date-parts":[[2017,1,3]],"date-time":"2017-01-03T12:40:46Z","timestamp":1483447246000},"page":"8657-8669","source":"Crossref","is-referenced-by-count":22,"title":["Selected patients can benefit more from the management of etoposide and platinum-based chemotherapy and thoracic irradiation-a retrospective analysis of 707 small cell lung cancer patients"],"prefix":"10.18632","volume":"8","author":[{"given":"Shoubo","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyan","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingwei","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2016,12,31]]},"reference":[{"issue":"27","key":"1","first-page":"158","article-title":"Prognostic factors and prognostic staging system for small cell lung cancer","volume":"1997","author":"Furuse","journal-title":"Jpn J Clin Oncol"},{"issue":"12","key":"2","first-page":"1096","article-title":"Small cell lung cancer: have we made any progress over the last 25 years?","volume":"2007","author":"Perry","journal-title":"Oncologist"},{"issue":"46","key":"3","first-page":"4189","article-title":"Prognostic factors in small cell lung cancer: multivariate model based on 778 patients treated with chemotherapy with or without irradiation","volume":"1986","author":"Andersen","journal-title":"Cancer Res"},{"issue":"8","key":"4","first-page":"547","article-title":"Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients","volume":"1997","author":"Reyn\u00e9s","journal-title":"Ann Oncol"},{"issue":"39","key":"5","first-page":"146","article-title":"Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients","volume":"1987","author":"Thatcher","journal-title":"Int J Cancer"},{"issue":"45","key":"6","first-page":"2878","article-title":"Prognostic significance of laboratory parameters measured at diagnosis in small cell carcinoma of the lung","volume":"1985","author":"Tobias","journal-title":"Cancer Res"},{"issue":"61","key":"7","first-page":"597","article-title":"An overview of prognostic factors in small cell lung cancer. A report from the subcommittee for the management of lung cancer of the United Kingdom coordinating committee on cancer research","volume":"1990","author":"Peto","journal-title":"Br J Cancer"},{"issue":"8","key":"8","first-page":"1042","article-title":"Outcome of patients with small-cell lung cancer: effect of changes in staging procedures and imaging technology on prognostic factors over 14 years","volume":"1990","author":"Johnson","journal-title":"J Clin Oncol"},{"issue":"89","key":"9","first-page":"523","article-title":"Prognostic factors for patients with small cell lung carcinoma: analysis of a series of 763 patients included in 4consecutive prospective trials with a minimum follow-up of 5 years","volume":"2000","author":"Klastersky","journal-title":"Cancer"},{"issue":"454","key":"10","first-page":"436","article-title":"Cancer-related inflammation","volume":"2008","author":"Balkwill","journal-title":"Nature"},{"issue":"125","key":"11","first-page":"3347","article-title":"Immunity, inflammation, and cancer: an eternal fight between good and evil","volume":"2015","author":"Karin","journal-title":"J Clin Invest"},{"issue":"12","key":"12","first-page":"298","article-title":"The immune contexture in human tumours: impact on clinical outcome","volume":"2012","author":"Galon","journal-title":"Nat Rev Cancer"},{"issue":"31","key":"13","first-page":"860","article-title":"Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98","volume":"2013","author":"Di Leo","journal-title":"J Clin Oncol"},{"issue":"71","key":"14","first-page":"5670","article-title":"Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy","volume":"2011","author":"Beckhove","journal-title":"Cancer Res"},{"issue":"6","key":"15","first-page":"275","article-title":"Combination of platelet to lymphocyte ratio and neutrophil to lymphocyte ratio is a useful prognostic factor in advanced non-small cell lung cancer patients","volume":"2015","author":"Song","journal-title":"Thorac Cancer"},{"issue":"31","key":"16","first-page":"323","article-title":"Prognostic significance of the lymphocyte-to-monocyte ratio in patients with small cell lung cancer","volume":"2014","author":"Kang","journal-title":"Med Oncol"},{"issue":"90","key":"17","first-page":"111","article-title":"Prognostic significance of the lymphocyte-to-monocyte ratio in patients with malignant pleural mesothelioma","volume":"2015","author":"Kishimoto","journal-title":"Lung Cancer"},{"issue":"36","key":"18","first-page":"8537","article-title":"Preoperative lymphocyte-monocyte and platelet-lymphocyte ratios as predictors of overall survival in patients with bladder cancer undergoing radical cystectomy","volume":"2015","author":"Ye","journal-title":"Tumour Biol"},{"issue":"31","key":"19","first-page":"305","article-title":"The prognostic value of preoperative NLR, d-NLR, PLR and LMR for predicting clinical outcome in surgical colorectal cancer patients","volume":"2014","author":"Wang","journal-title":"Med Oncol"},{"issue":"10","key":"20","first-page":"e0143061","article-title":"The Peripheral Blood Neutrophil-To Lymphocyte Ratio Is Superior to the Lymphocyte-To-Monocyte Ratio for Predicting the Long-Term Survival of Triple Negative Breast Cancer Patients","volume":"2015","author":"Su","journal-title":"PLoS One"},{"issue":"69","key":"21","first-page":"633","article-title":"Prognostic significance of pretreatment laboratory parameters in combined small-cell lung cancer","volume":"2014","author":"Li","journal-title":"Cell Biochem Biophys"},{"issue":"6","key":"22","first-page":"283","article-title":"Platelets and granulocytes, in particular the neutrophils, form important compartments for circulating vascular endothelial growth factor","volume":"2003","author":"Mulder","journal-title":"Angiogenesis"},{"key":"23","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/bjc.2015.61","article-title":"Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer","volume":"112","author":"Menter","year":"2015","journal-title":"Br J Cancer"},{"issue":"104","key":"24","first-page":"1937","article-title":"Lactate dehydrogenase as prognostic factor in limited and extensive disease stage small cell lung cancer-A retrospective single institution analysis","volume":"2010","author":"Reck","journal-title":"Respir Med"},{"issue":"107","key":"25","first-page":"422","article-title":"Serum markers lactate dehydrogenase and S100B predict independently disease outcome in melanoma patients with distant metastasis","volume":"2012","author":"Garbe","journal-title":"Br J Cancer"},{"issue":"97","key":"26","first-page":"39","article-title":"Alkaline phosphatase levels as a prognostic factor in metastatic colorectal cancer treated with the FOLFOX 4 regimen: a monoinstitutional retrospective study","volume":"2011","author":"Nardi","journal-title":"Tumori"},{"issue":"30","key":"27","first-page":"607","article-title":"Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy","volume":"2012","author":"Tannock","journal-title":"Urol Oncol"},{"issue":"20","key":"28","first-page":"746","article-title":"CALy Prognostic Score (CEA ALP Lymphocyte Count) as a predictor of survival after hepatectomy for liver-only colorectal metastases","volume":"2015","author":"Mudan","journal-title":"J BUON"},{"issue":"37","key":"29","first-page":"1879","article-title":"The predictive value of alkaline phosphatase and lactate dehydrogenase for overall survival in patients with esophageal squamous cell carcinoma","volume":"2016","author":"Xu","journal-title":"Tumour Biol"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.14395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T16:21:12Z","timestamp":1589127672000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.14395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,31]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,1,31]]}},"alternative-id":["14395","28055965"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.14395","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,31]]}}}