{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:04:11Z","timestamp":1792800251504,"version":"4.5.0"},"reference-count":27,"publisher":"Impact Journals, LLC","issue":"44","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,9,29]]},"DOI":"10.18632\/oncotarget.18546","type":"journal-article","created":{"date-parts":[[2017,6,17]],"date-time":"2017-06-17T14:13:54Z","timestamp":1497708834000},"page":"76099-76107","source":"Crossref","is-referenced-by-count":29,"title":["The correlation of neutrophil-to-lymphocyte ratio with the presence and activity of myasthenia gravis"],"prefix":"10.18632","volume":"8","author":[{"given":"De-Hao","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Zi","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao-Mao","family":"Wei","sequence":"additional","affiliation":[{"name":"School of the First Clinical Medical Sciences, Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Meng","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Mian","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yan","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of the First Clinical Medical Sciences, Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2017,6,16]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.bcp.2015.07.011","article-title":"AChR-specific immunosuppressive therapy of myasthenia gravis","volume":"97","author":"Lindstrom","year":"2015","journal-title":"Biochem Pharmacol"},{"key":"2","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1212\/WNL.41.9.1497","article-title":"Inflammation at the neuromuscular junction in myasthenia gravis","volume":"41","author":"Wollmann","year":"1991","journal-title":"Neurology"},{"key":"3","doi-asserted-by":"publisher","first-page":"7550","DOI":"10.18632\/oncotarget.6885","article-title":"Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis","volume":"7","author":"Le Panse","year":"2016","journal-title":"Oncotarget"},{"key":"4","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.immuni.2011.10.015","article-title":"Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation","volume":"35","author":"Kuchroo","year":"2011","journal-title":"Immunity"},{"key":"5","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jaut.2010.12.001","article-title":"Blocking of IL-6 suppresses experimental autoimmune myasthenia gravis","volume":"36","author":"Souroujon","year":"2011","journal-title":"J Autoimmun"},{"key":"6","doi-asserted-by":"crossref","first-page":"25886","DOI":"10.1038\/srep25886","article-title":"Changes in inflammatory cytokine networks in myasthenia gravis","volume":"6","author":"Kuwabara","year":"2016","journal-title":"Sci Rep"},{"key":"7","first-page":"8191254","article-title":"Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Patients with Sepsis: A Prospective Observational Study","volume":"2016","author":"Pan","year":"2016","journal-title":"Mediators Inflamm"},{"key":"8","doi-asserted-by":"crossref","first-page":"E257","DOI":"10.1002\/lary.25204","article-title":"The significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in vestibular neuritis","volume":"125","author":"Lee","year":"2015","journal-title":"Laryngoscope"},{"key":"9","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/1346-8138.13061","article-title":"Assessments of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in Korean patients with psoriasis vulgaris and psoriatic arthritis","volume":"43","author":"Lee","year":"2016","journal-title":"J Dermatol"},{"key":"10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1007\/s10157-012-0728-x","article-title":"Neutrophil to lymphocyte ratio independently predicts cardiovascular events in patients with chronic kidney disease","volume":"17","author":"Gaipov","year":"2013","journal-title":"Clin Exp Nephrol"},{"key":"11","doi-asserted-by":"publisher","first-page":"50963","DOI":"10.18632\/oncotarget.7680","article-title":"Elevated neutrophil-to-lymphocyte ratio is an independent poor prognostic factor in patients with intrahepatic cholangiocarcinoma","volume":"7","author":"Li","year":"2016","journal-title":"Oncotarget"},{"key":"12","doi-asserted-by":"crossref","first-page":"e0156101","DOI":"10.1371\/journal.pone.0156101","article-title":"Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictive and Prognostic Factor for High-Grade Serous Ovarian Cancer","volume":"11","author":"Wu","year":"2016","journal-title":"PLoS One"},{"key":"13","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/s12885-016-2219-z","article-title":"Neutrophil-to-lymphocyte ratio is a prognostic marker in bladder cancer patients after radical cystectomy","volume":"16","author":"Yamanaka","year":"2016","journal-title":"BMC Cancer"},{"key":"14","first-page":"213","article-title":"Neutrophil-to-lymphocyte ratio in inflammatory bowel disease - as a new predictor of disease severity","volume":"116","author":"Yuksel","year":"2015","journal-title":"Bratisl Lek Listy"},{"key":"15","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.kjms.2015.10.010","article-title":"The relation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume with the presence and severity of Behcet's syndrome","volume":"31","author":"Turkoglu","year":"2015","journal-title":"Kaohsiung J Med Sci"},{"key":"16","first-page":"700","article-title":"The clinical significance of the neutrophil-to-lymphocyte ratio in multiple sclerosis","volume":"126","author":"Yurekli","year":"2016","journal-title":"Int J Neurosci"},{"key":"17","article-title":"Thymic Germinal Centers and Corticosteroids in Myasthenia Gravis: an Immunopathological Study in 1035 Cases and a Critical Review","author":"Berrih-Aknin","year":"2016","journal-title":"Clin Rev Allergy Immunol"},{"key":"18","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.autrev.2013.03.010","article-title":"Etiology of myasthenia gravis: innate immunity signature in pathological thymus","volume":"12","author":"Le Panse","year":"2013","journal-title":"Autoimmun Rev"},{"key":"19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jaut.2013.12.015","article-title":"Both Treg cells and Tconv cells are defective in the Myasthenia gravis thymus: roles of IL-17 and TNF-alpha","volume":"52","author":"Berrih-Aknin","year":"2014","journal-title":"J Autoimmun"},{"key":"20","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.5551\/jat.25940","article-title":"Usefulness of the neutrophil-to-lymphocyte ratio in predicting the severity of coronary artery disease: a Gensini score assessment","volume":"21","author":"Li","year":"2014","journal-title":"J Atheroscler Thromb"},{"key":"21","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/ije\/19.4.889","article-title":"The leucocyte count: correlates and relationship to coronary risk factors: the CARDIA study","volume":"19","author":"Sidney","year":"1990","journal-title":"Int J Epidemiol"},{"key":"22","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.ahj.2007.06.043","article-title":"Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting","volume":"154","author":"Hillis","year":"2007","journal-title":"Am Heart J"},{"key":"23","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.amjcard.2007.11.004","article-title":"Usefulness of the neutrophil to lymphocyte ratio in predicting long-term mortality in ST segment elevation myocardial infarction","volume":"101","author":"Llacer","year":"2008","journal-title":"Am J Cardiol"},{"key":"24","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/jcla.21908","article-title":"The Association Between Neutrophil\/Lymphocyte Ratio and Disease Activity in Rheumatoid Arthritis and Ankylosing Spondylitis","volume":"30","author":"Goker","year":"2016","journal-title":"J Clin Lab Anal"},{"key":"25","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1089\/dia.2013.0097","article-title":"Neutrophil-to-lymphocyte ratio as a quick and reliable predictive marker to diagnose the severity of diabetic retinopathy","volume":"15","author":"Inan","year":"2013","journal-title":"Diabetes Technol Ther"},{"key":"26","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1056\/NEJM199406233302507","article-title":"Myasthenia gravis","volume":"330","author":"Drachman","year":"1994","journal-title":"N Engl J Med"},{"key":"27","first-page":"327","article-title":"Myasthenia gravis: recommendations for clinical research standards","volume":"70","author":"Sanders","year":"2000","journal-title":"Ann Thorac Surg"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.18546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,9]],"date-time":"2020-08-09T17:47:56Z","timestamp":1596995276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.18546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,16]]},"references-count":27,"journal-issue":{"issue":"44","published-print":{"date-parts":[[2017,9,29]]}},"alternative-id":["18546","29100295"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.18546","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,16]]}}}