{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:29:55Z","timestamp":1788877795683,"version":"build-2803163510"},"reference-count":39,"publisher":"Impact Journals, LLC","issue":"45","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,10,3]]},"DOI":"10.18632\/oncotarget.19565","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T16:50:16Z","timestamp":1501087816000},"page":"79803-79808","source":"Crossref","is-referenced-by-count":17,"title":["Loneliness and its impact on quality of life in Chinese heroin-dependent patients receiving methadone maintenance treatment"],"prefix":"10.18632","volume":"8","author":[{"given":"Ying-Jia","family":"Yang","sequence":"first","affiliation":[{"name":"Shenzhen Key Laboratory for Psychological Healthcare, Shenzhen Institute of Mental Health, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen, Guangdong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Min","family":"Xu","sequence":"additional","affiliation":[{"name":"Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Cai","family":"Chen","sequence":"additional","affiliation":[{"name":"Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Liang","family":"Zhong","sequence":"additional","affiliation":[{"name":"Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2017,7,26]]},"reference":[{"key":"1","first-page":"1","article-title":"Indirect Effects of Loneliness on Substance Use through Stress","volume":"3","author":"Pavlich","year":"2017","journal-title":"Health Commun"},{"key":"2","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1080\/09540121.2015.1120269","article-title":"Loneliness and substance use: the influence of gender among HIV+ Black\/African American adults 50+","volume":"28","author":"Whitehead","year":"2016","journal-title":"AIDS Care"},{"key":"3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0277-9536(92)90300-F","article-title":"Loneliness and alcohol abuse: a review of evidences of an interplay","volume":"34","author":"Hornquist","year":"1992","journal-title":"Soc Sci Med"},{"key":"4","first-page":"46","article-title":"The Molecular Neurobiology of Twelve Steps Program & Fellowship: Connecting the Dots for Recovery","volume":"1","author":"Gold","year":"2015","journal-title":"J Reward Defic Syndr"},{"key":"5","first-page":"e22688","article-title":"Emotional and social loneliness in individuals with and without substance dependence disorder","volume":"3","author":"Bakhshani","year":"2014","journal-title":"Int J High Risk Behav Addict"},{"key":"6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/add.12781","article-title":"National Methadone Maintenance Treatment Working G. Who uses methadone services in China? Monitoring the world\u2019s largest methadone programme","volume":"110","author":"Mi","year":"2015","journal-title":"Addiction"},{"key":"7","doi-asserted-by":"crossref","first-page":"e008162","DOI":"10.1136\/bmjopen-2015-008162","article-title":"Trends and risk factors for HIV, HCV and syphilis seroconversion among drug users in a methadone maintenance treatment programme in China: a 7-year retrospective cohort study","volume":"5","author":"Zhang","year":"2015","journal-title":"BMJ Open"},{"key":"8","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/pubmed\/fds079","article-title":"Methadone maintenance treatment in China: perceived challenges from the perspectives of service providers and patients","volume":"35","author":"Hser","year":"2013","journal-title":"J Public Health (Oxf)"},{"key":"9","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jad.2016.09.003","article-title":"Rates and characteristics of elderly suicide in China, 2013-14","volume":"206","author":"Conwell","year":"2016","journal-title":"J Affect Disord"},{"key":"10","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jagp.2015.12.009","article-title":"Effects of Transient Versus Chronic Loneliness on Cognitive Function in Older Adults: Findings From the Chinese Longitudinal Healthy Longevity Survey","volume":"24","author":"Conwell","year":"2016","journal-title":"Am J Geriatr Psychiatry"},{"key":"11","doi-asserted-by":"crossref","first-page":"e3903","DOI":"10.1097\/MD.0000000000003903","article-title":"Prevalence and correlates of loneliness among Chinese service industry migrant workers: A cross-sectional survey","volume":"95","author":"Liu","year":"2016","journal-title":"Medicine"},{"key":"12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/ADM.0000000000000180","article-title":"Predictors of Poor Adherence to Methadone Maintenance Treatment in Yunnan Province, China","volume":"10","author":"Li","year":"2016","journal-title":"J Addict Med"},{"key":"13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0140-6736(14)60175-6","article-title":"Drug policy in China: progress and challenges","volume":"383","author":"Xiao","year":"2014","journal-title":"Lancet"},{"key":"14","first-page":"259","article-title":"Prevalence of antisocial personality disorder among Chinese individuals receiving treatment for heroin dependence: a meta-analysis","volume":"26","author":"Chiu","year":"2014","journal-title":"Shanghai Arch Psychiatry"},{"key":"15","first-page":"58","article-title":"Reliability and validity of Chinese eition of the World Health Organization\u2019s Quality of Life Questionnaire-Brief Version for outpatients on methadone maintenance treatment","volume":"20","author":"Zhong","year":"2011","journal-title":"Chin J Drug Depend"},{"key":"16","first-page":"833","article-title":"Drug addiction maintenance treatment and quality of life measurements","volume":"40","author":"Subata","year":"2004","journal-title":"Medicina (Kaunas)"},{"key":"17","first-page":"299","article-title":"Quality of life and its associated factors of heroin dependent patients receiving methadone -maintainance treatment","volume":"23","author":"Liu","year":"2014","journal-title":"Chin J Drug Depend"},{"key":"18","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1097\/QAI.0b013e3181c7dfb5","article-title":"Quality of life of outpatients in methadone maintenance treatment clinics","volume":"53","author":"Wei","year":"2010","journal-title":"J Acquir Immune Defic Syndr"},{"key":"19","first-page":"44","article-title":"Pain and its association with quality of life in heroin-dependent patients receiving methadone maintenance treatment","volume":"23","author":"Zhu","year":"2017","journal-title":"Chin J Pain Med"},{"key":"20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.kjms.2010.09.003","article-title":"Quality of life and its correlates among heroin users in Taiwan","volume":"27","author":"Chang","year":"2011","journal-title":"Kaohsiung J Med Sci"},{"key":"21","first-page":"43","article-title":"Loneliness in Elderly People, Associated Factors and Its Correlation with Quality of Life: A Field Study from Western Turkey","volume":"44","author":"Acar","year":"2015","journal-title":"Iran J Public Health"},{"key":"22","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1093\/geronb\/gbw037","article-title":"Loneliness and Cognitive Function in Older Adults: Findings From the Chinese Longitudinal Healthy Longevity Survey","volume":"72","author":"Conwell","year":"2017","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"23","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.socscimed.2011.11.028","article-title":"Loneliness, health, and mortality in old age: a national longitudinal study","volume":"74","author":"Cacioppo","year":"2012","journal-title":"Soc Sci Med"},{"key":"24","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1037\/a0017805","article-title":"Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults","volume":"25","author":"Cacioppo","year":"2010","journal-title":"Psychol Aging"},{"key":"25","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1037\/a0017216","article-title":"Perceived social isolation makes me sad: 5-year cross-lagged analyses of loneliness and depressive symptomatology in the Chicago Health, Aging, and Social Relations Study","volume":"25","author":"Thisted","year":"2010","journal-title":"Psychol Aging"},{"key":"26","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1037\/a0014400","article-title":"Loneliness predicts reduced physical activity: cross-sectional & longitudinal analyses","volume":"28","author":"Cacioppo","year":"2009","journal-title":"Health Psychol"},{"key":"27","first-page":"48","article-title":"Social exclusion and social inclusion: difficulties and solutions for returning to society of illicit drug users","volume":"305","author":"Lin","year":"2015","journal-title":"Guizhou Soc Sci"},{"key":"28","article-title":"Loneliness in New Zealand: Findings from the 2010 NZ General Social Survey","author":"Statistics New Zealand","year":"2013","journal-title":"(Wellington, New Zealand: Statistics New Zealand)"},{"key":"29","article-title":"Social relations and loneliness among older patients consulting their general practitioner","volume":"64","author":"Waldorff","year":"2017","journal-title":"Dan Med J"},{"key":"30","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/13607863.2014.944091","article-title":"Predictors of loneliness among older women and men in Sweden: A national longitudinal study","volume":"19","author":"Lennartsson","year":"2015","journal-title":"Aging Ment Health"},{"key":"31","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000091828","article-title":"Social contacts and their relationship to loneliness among aged people - a population-based study","volume":"52","author":"Pitkala","year":"2006","journal-title":"Gerontology"},{"key":"32","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.archger.2014.06.010","article-title":"Loneliness in middle and old age: demographics, perceived health, and social satisfaction as predictors","volume":"59","author":"Simoes","year":"2014","journal-title":"Arch Gerontol Geriatr"},{"key":"33","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1007\/s00127-016-1281-9","article-title":"Causal inference and longitudinal data: a case study of religion and mental health","volume":"51","author":"Li","year":"2016","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"34","doi-asserted-by":"crossref","first-page":"e0157530","DOI":"10.1371\/journal.pone.0157530","article-title":"Acculturative Stress of Chinese Rural-To-Urban Migrant Workers: A Qualitative Study","volume":"11","author":"Chiu","year":"2016","journal-title":"PLoS One"},{"key":"35","first-page":"298","article-title":"Association between loneliness and risks of depressive episode among rural older people","volume":"42","author":"Zhou","year":"2017","journal-title":"J Cent South Univ (Med Sci)"},{"key":"36","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1037\/0882-7974.21.1.140","article-title":"Loneliness as a specific risk factor for depressive symptoms: cross-sectional and longitudinal analyses","volume":"21","author":"Thisted","year":"2006","journal-title":"Psychol Aging"},{"key":"37","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1093\/geronb\/gbu013","article-title":"Self-rated health changes and oldest-old mortality","volume":"69","author":"Vogelsang","year":"2014","journal-title":"J Gerontol B Psychol Sci Soc Sci"},{"key":"38","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1017\/S0959259805001723","article-title":"Measuring loneliness in later life: a comparison of differing measures","volume":"15","author":"Boldy","year":"2005","journal-title":"Rev Clin Gerontol"},{"key":"39","first-page":"1","article-title":"Common mental health problems in rural-to-urban migrant workers in Shenzhen","author":"Chiu","year":"2017","journal-title":"China: prevalence and risk factors. Epidemiol Psychiatr Sci"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.19565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T13:05:34Z","timestamp":1589202334000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.19565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,26]]},"references-count":39,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2017,10,3]]}},"alternative-id":["19565","29108361"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.19565","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,26]]}}}