{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:15:52Z","timestamp":1792080952526,"version":"4.4.0"},"reference-count":33,"publisher":"Impact Journals, LLC","issue":"64","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2017,12,8]]},"DOI":"10.18632\/oncotarget.22534","type":"journal-article","created":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T06:51:59Z","timestamp":1511160719000},"page":"107577-107588","source":"Crossref","is-referenced-by-count":74,"title":["Alterations in the mucosa-associated fungal microbiota in patients with ulcerative colitis"],"prefix":"10.18632","volume":"8","author":[{"given":"Xinyun","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhua","family":"Jiao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaqiong","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijiao","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7892","published-online":{"date-parts":[[2017,11,20]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.18632\/oncotarget.13715","article-title":"Chemopreventive effects of 5-aminosalicylic acid on inflammatory bowel disease-associated colorectal cancer and dysplasia: a systematic review with meta-analysis","volume":"8","author":"Zhang","year":"2017","journal-title":"Oncotarget"},{"key":"2","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1023\/A:1020841601110","article-title":"Factors affecting health related quality of life of patients with inflammatory bowel disease","volume":"11","author":"Malagelada","year":"2002","journal-title":"Qual Life Res"},{"key":"3","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1053\/j.gastro.2014.02.009","article-title":"The microbiome in inflammatory bowel disease: current status and the future ahead","volume":"146","author":"Gevers","year":"2014","journal-title":"Gastroenterology"},{"key":"4","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1136\/gutjnl-2014-307410","article-title":"Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific","volume":"64","author":"Ooi","year":"2015","journal-title":"Gut"},{"key":"5","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.pharmthera.2014.12.006","article-title":"The involvement of gut microbiota in inflammatory bowel disease pathogenesis: potential for therapy","volume":"149","author":"Curro","year":"2015","journal-title":"Pharmacol Ther"},{"key":"6","doi-asserted-by":"crossref","first-page":"65995","DOI":"10.1039\/C6RA03869G","article-title":"Fungal-bacterial interactions in mice with dextran sulfate sodium (DSS)-induced acute and chronic colitis","volume":"6","author":"Liu","year":"2016","journal-title":"RSC Adv"},{"key":"7","doi-asserted-by":"crossref","first-page":"e66019","DOI":"10.1371\/journal.pone.0066019","article-title":"Archaea and fungi of the human gut microbiome: correlations with diet and bacterial residents","volume":"8","author":"Bushman","year":"2013","journal-title":"PLoS One"},{"key":"8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nri3684","article-title":"The mycobiota: interactions between commensal fungi and the host immune system","volume":"14","author":"Lliev","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"9","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.crohns.2014.01.024","article-title":"A novel gas chromatography mass spectrometry-based serum diagnostic and assessment approach to ulcerative colitis","volume":"8","author":"Yoshida","year":"2014","journal-title":"J Crohns Colitis"},{"key":"10","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jim.2006.05.013","article-title":"Soluble Dectin-1 as a tool to detect \u03b2-glucans","volume":"314","author":"Brown","year":"2006","journal-title":"J Immunol Methods"},{"key":"11","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1126\/science.1221789","article-title":"Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis","volume":"336","author":"McGovern","year":"2012","journal-title":"Science"},{"key":"12","doi-asserted-by":"crossref","first-page":"10416","DOI":"10.1038\/srep10416","article-title":"Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis","volume":"5","author":"Liu","year":"2015","journal-title":"Sci Rep"},{"key":"13","first-page":"107","article-title":"Effect of Candida colonization on human ulcerative colitis and the healing of inflammatory changes of the colon in the experimental model of colitis ulcerosa","volume":"60","author":"Pawlik","year":"2009","journal-title":"J Physiol Pharmacol"},{"key":"14","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1136\/gutjnl-2015-310746","article-title":"Fungal microbiota dysbiosis in IBD","volume":"66","author":"Langella","year":"2017","journal-title":"Gut"},{"key":"15","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/MCG.0000000000000035","article-title":"Dysbiosis of Gut Fungal Microbiota is Associated With Mucosal Inflammation in Crohn's Disease","volume":"48","author":"Li","year":"2014","journal-title":"J Clin Gastroenterol"},{"key":"16","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.chom.2015.09.008","article-title":"Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn's Disease","volume":"18","author":"Compher","year":"2015","journal-title":"Cell Host Microbe"},{"key":"17","doi-asserted-by":"crossref","first-page":"7980","DOI":"10.1038\/srep07980","article-title":"Dysbiosis of fungal microbiota in the intestinal mucosa of patients with colorectal adenomas","volume":"5","author":"Zhu","year":"2015","journal-title":"Sci Rep"},{"key":"18","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1093\/ecco-jcc\/jjv209","article-title":"Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn's Disease Patients","volume":"10","author":"Sokol","year":"2016","journal-title":"J Crohns Colitis"},{"key":"19","unstructured":"Suhr. Characterization and Investigation of Fungi Inhabiting the Gastrointestinal Tract of Healthy and Diseased Humans. Dissertations & Theses in Food Science and Technology. 2015; pp. 1\u2013149. http:\/\/digitalcommons.unl.edu\/foodscidiss\/53\/."},{"key":"20","doi-asserted-by":"publisher","first-page":"rjt091","DOI":"10.1093\/jscr\/rjt091","article-title":"Disseminated enteroinvasive aspergillosis in a critically ill patient without severe immunocompromise","volume":"11","author":"Longo","year":"2013","journal-title":"J Surg Case Rep"},{"key":"21","first-page":"316","article-title":"Invasive pulmonary aspergillosis in an immunocompromised patient with severe ulcerative colitis","volume":"109","author":"Bosca-Watts","year":"2017","journal-title":"Rev Esp Enferm Dig"},{"key":"22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00281-014-0462-4","article-title":"Pattern recognition receptors in antifungal immunity","volume":"37","author":"Brown","year":"2015","journal-title":"Semin Immunopathol"},{"key":"23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nri3684","article-title":"The mycobiota: interactions between commensal fungi and the host immune system","volume":"14","author":"Iliev","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"24","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nri3661","article-title":"Cytokines in inflammatory bowel disease","volume":"14","author":"Neurath","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"25","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1128\/AEM.03491-12","article-title":"Heterologous expression of a bioactive beta-hexosyltransferase, an enzyme producer of prebiotics, from Sporobolomyces singularis","volume":"79","author":"Bruno-Barcena","year":"2013","journal-title":"Appl Environ Microbiol"},{"key":"26","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/ptr.3378","article-title":"Coriolus versicolor suppresses inflammatory bowel disease by Inhibiting the expression of STAT1 and STAT6 associated with IFN-gamma and IL-4 expression","volume":"25","author":"Lim","year":"2011","journal-title":"Phytother Res"},{"key":"27","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1111\/1751-2980.12422","article-title":"Therapeutic modulation of gut microbiota in inflammatory bowel disease: More questions to be answered","volume":"17","author":"Ran","year":"2016","journal-title":"J Dig Dis"},{"key":"28","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/ecco-jcc\/jjx008","article-title":"Third European Evidence-Based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, diagnosis, extra-intestinal manifestations, pregnancy, cancer surveillance, surgery, and ileo-anal pouch disorders","volume":"11","author":"Pellino","year":"2017","journal-title":"J Crohns Colitis"},{"key":"29","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1056\/NEJMoa042982","article-title":"Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin","volume":"352","author":"Vandervoort","year":"2005","journal-title":"N Engl J Med"},{"key":"30","first-page":"5498","article-title":"Serum IL-17 and IL-6 increased accompany with TGF-beta and IL-13 respectively in ulcerative colitis patients","volume":"7","author":"Zheng","year":"2014","journal-title":"Int J Clin Exp Med"},{"key":"31","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00248-013-0245-9","article-title":"Dysbiosis signature of fecal microbiota in colorectal cancer patients","volume":"66","author":"Wang","year":"2013","journal-title":"Microb Ecol"},{"key":"32","first-page":"306","article-title":"The mathematical theory of communication. 1963","volume":"14","author":"Shannon","year":"1997","journal-title":"MD Comput"},{"key":"33","doi-asserted-by":"crossref","first-page":"2840","DOI":"10.1097\/01.MIB.0000435440.22484.e8","article-title":"Comparative study of candidate housekeeping genes for quantification of target gene messenger RNA expression by real-time PCR in patients with inflammatory bowel disease","volume":"19","author":"Ladas","year":"2013","journal-title":"Inflamm Bowel Dis"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.22534","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T14:42:26Z","timestamp":1596724946000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.22534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,20]]},"references-count":33,"journal-issue":{"issue":"64","published-print":{"date-parts":[[2017,12,8]]}},"alternative-id":["22534","29296188"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.22534","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,20]]}}}