{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:31:02Z","timestamp":1779165062312,"version":"3.51.4"},"reference-count":46,"publisher":"Impact Journals, LLC","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2018,1,9]]},"DOI":"10.18632\/oncotarget.23234","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T16:41:44Z","timestamp":1513269704000},"page":"3303-3320","source":"Crossref","is-referenced-by-count":10,"title":["Specific alterations in gut microbiota are associated with prognosis of Budd-Chiari syndrome"],"prefix":"10.18632","volume":"9","author":[{"given":"Yu-Ling","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Qi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng-Xu","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Radioactive Intervention, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radioactive Intervention, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Hua","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Diagnosis, The People\u2019s Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiu-Xian","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-Fang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Diagnosis, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Digestive Diseases, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruo-Peng","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Peng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Pu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong-Tao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China"},{"name":"Institute of Hepatobiliary and Pancreatic Diseases, Zhengzhou University, Zhengzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2017,12,14]]},"reference":[{"key":"1","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.jhep.2008.10.007","article-title":"Primary Budd-Chiari syndrome","volume":"50","author":"Valla","year":"2009","journal-title":"J Hepatol"},{"key":"2","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1002\/hep.22772","article-title":"Vascular disorders of the liver","volume":"49","author":"Garcia-Tsao","year":"2009","journal-title":"Hepatology"},{"key":"3","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1002\/hep.27628","article-title":"Difference in Budd-Chiari syndrome between the West and China","volume":"62","author":"Fan","year":"2015","journal-title":"Hepatology"},{"key":"4","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1136\/gutjnl-2012-302471","article-title":"Compensation by collateral circulation determines invasive therapeutic indications for patients with Budd-Chiari syndrome","volume":"61","author":"Wang","year":"2012","journal-title":"Gut"},{"key":"5","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/S0168-8278(02)00434-8","article-title":"Budd-Chiari syndrome: a review by an expert panel","volume":"38","author":"Valla","year":"2003","journal-title":"J Hepatol"},{"key":"6","doi-asserted-by":"publisher","first-page":"1962","DOI":"10.1002\/hep.26306","article-title":"Good long-term outcome of Budd-Chiari syndrome with a step-wise management","volume":"57","author":"Hadengue","year":"2013","journal-title":"Hepatology"},{"key":"7","first-page":"499","article-title":"Obliterative hepatocavopathy-inferior vena cava thrombosis at its hepatic portion","volume":"1","author":"Okuda","year":"2002","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"8","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/j.cell.2006.02.017","article-title":"Ecological and evolutionary forces shaping microbial diversity in the human intestine","volume":"124","author":"Gordon","year":"2006","journal-title":"Cell"},{"key":"9","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1038\/nature05698","article-title":"Epithelial NEMO links innate immunity to chronic intestinal inflammation","volume":"446","author":"Pasparakis","year":"2007","journal-title":"Nature"},{"key":"10","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1126\/science.1124234","article-title":"Metagenomic analysis of the human distal gut microbiome","volume":"312","author":"Nelson","year":"2006","journal-title":"Science"},{"key":"11","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nature11450","article-title":"A metagenome-wide association study of gut microbiota in type 2 diabetes","volume":"490","author":"Jie","year":"2012","journal-title":"Nature"},{"key":"12","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1038\/nrmicro3089","article-title":"The gut microbiota and obesity: from correlation to causality","volume":"11","author":"Zhao","year":"2013","journal-title":"Nat Rev Microbiol"},{"key":"13","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1136\/gutjnl-2012-303816","article-title":"Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice","volume":"62","author":"G\u00e9rard","year":"2013","journal-title":"Gut"},{"key":"14","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1002\/hep.26093","article-title":"Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH","volume":"57","author":"Gill","year":"2013","journal-title":"Hepatology"},{"key":"15","doi-asserted-by":"publisher","first-page":"e75950","DOI":"10.1371\/journal.pone.0075950","article-title":"Liver ischemic preconditioning (IPC) improves intestinal microbiota following liver transplantation in rats through 16s rDNA-based analysis of microbial structure shift","volume":"8","author":"Zheng","year":"2013","journal-title":"PLoS One"},{"key":"16","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1002\/hep.24423","article-title":"Characterization of fecal microbial communities in patients with liver cirrhosis","volume":"54","author":"Li","year":"2011","journal-title":"Hepatology"},{"key":"17","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.ccr.2012.02.007","article-title":"Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4","volume":"21","author":"Friedman","year":"2012","journal-title":"Cancer Cell"},{"key":"18","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1097\/TP.0000000000000334","article-title":"Intestinal microbial variation may predict early acute rejection after liver transplantation in rats","volume":"98","author":"Zhou","year":"2014","journal-title":"Transplantation"},{"key":"19","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.26494","article-title":"Microbiota-liver axis in hepatic disease","volume":"59","author":"Gewirtz","year":"2014","journal-title":"Hepatology"},{"key":"20","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1053\/j.gastro.2014.01.020","article-title":"Interactions between the intestinal microbiome and liver diseases","volume":"146","author":"Brenner","year":"2014","journal-title":"Gastroenterology"},{"key":"21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/nature13568","article-title":"Alterations of the human gut microbiome in liver cirrhosis","volume":"513","author":"Liu","year":"2014","journal-title":"Nature"},{"key":"22","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1038\/nbt.2676","article-title":"Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences","volume":"31","author":"Huttenhower","year":"2013","journal-title":"Nat Biotechnol"},{"key":"23","doi-asserted-by":"publisher","first-page":"e1002358","DOI":"10.1371\/journal.pcbi.1002358","article-title":"Metabolic reconstruction for metagenomic data and its application to the human microbiome","volume":"8","author":"Meth\u00e9","year":"2012","journal-title":"PLOS Comput Biol"},{"key":"24","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1136\/gutjnl-2015-310500","article-title":"The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls","volume":"66","author":"Hov","year":"2017","journal-title":"Gut"},{"key":"25","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1136\/gutjnl-2015-309800","article-title":"Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer","volume":"66","author":"Chen","year":"2017","journal-title":"Gut"},{"key":"26","doi-asserted-by":"publisher","first-page":"2364","DOI":"10.1111\/j.1572-0241.2002.05791.x","article-title":"Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia","volume":"97","author":"Blum","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"27","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.jhep.2012.08.019","article-title":"Targeting gut flora to prevent progression of hepatocellular carcinoma","volume":"58","author":"Moniaux","year":"2013","journal-title":"J Hepatol"},{"key":"28","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/S1499-3872(11)60042-8","article-title":"Necessity and indications of invasive treatment for Budd-Chiari syndrome","volume":"10","author":"Luo","year":"2011","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"29","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1136\/gutjnl-2011-301501","article-title":"An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota","volume":"61","author":"Simr\u00e9n","year":"2012","journal-title":"Gut"},{"key":"30","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/j.immuni.2014.05.014","article-title":"Diet, metabolites, and \u201cwestern-lifestyle\u201d inflammatory diseases","volume":"40","author":"Mackay","year":"2014","journal-title":"Immunity"},{"key":"31","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1038\/nrmicro3344","article-title":"The gut microbiota, bacterial metabolites and colorectal cancer","volume":"12","author":"Flint","year":"2014","journal-title":"Nat Rev Microbiol"},{"key":"32","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.immuni.2014.05.015","article-title":"Finding the missing links among metabolites, microbes, and the host","volume":"40","author":"Knight","year":"2014","journal-title":"Immunity"},{"key":"33","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/j.cmet.2014.10.016","article-title":"Specialized metabolites from the microbiome in health and disease","volume":"20","author":"Mazmanian","year":"2014","journal-title":"Cell Metab"},{"key":"34","doi-asserted-by":"publisher","first-page":"168","DOI":"10.3389\/fphys.2010.00168","article-title":"Microbial induction of immunity, inflammation, and cancer","volume":"1","author":"O\u2019Keefe","year":"2011","journal-title":"Front Physiol"},{"key":"35","doi-asserted-by":"publisher","first-page":"C979","DOI":"10.1152\/ajpcell.00228.2014","article-title":"From microbe to man: the role of microbial short chain fatty acid metabolites in host cell biology","volume":"307","author":"Pluznick","year":"2014","journal-title":"Am J Physiol Cell Physiol"},{"key":"36","doi-asserted-by":"publisher","first-page":"e73","DOI":"10.1038\/cti.2016.17","article-title":"Regulation of immune cell function by short-chain fatty acids","volume":"5","author":"Vinolo","year":"2016","journal-title":"Clin Transl Immunology"},{"key":"37","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1172\/JCI2338","article-title":"LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria","volume":"101","author":"Schumann","year":"1998","journal-title":"J Clin Invest"},{"key":"38","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1093\/jnci\/djn326","article-title":"Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design","volume":"100","author":"Potter","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"39","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","article-title":"FLASH: fast length adjustment of short reads to improve genome assemblies","volume":"27","author":"Salzberg","year":"2011","journal-title":"Bioinformatics"},{"key":"40","doi-asserted-by":"publisher","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","article-title":"UCHIME improves sensitivity and speed of chimera detection","volume":"27","author":"Knight","year":"2011","journal-title":"Bioinformatics"},{"key":"41","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1038\/nmeth.2604","article-title":"UPARSE: highly accurate OTU sequences from microbial amplicon reads","volume":"10","author":"Edgar","year":"2013","journal-title":"Nat Methods"},{"key":"42","doi-asserted-by":"publisher","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Cole","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"43","unstructured":"Oksanen, Blanchet, Kindt, Legendre, Minchin, O\u2019Hara. Ordination methods, diversity analysis and other functions for community and vegetation ecologists. In: Vegan: Community Ecology Package. 05-26 ed; 2015."},{"key":"44","doi-asserted-by":"publisher","first-page":"e61217","DOI":"10.1371\/journal.pone.0061217","article-title":"phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data","volume":"8","author":"Holmes","year":"2013","journal-title":"PLoS One"},{"key":"45","doi-asserted-by":"publisher","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Huttenhower","year":"2011","journal-title":"Genome Biol"},{"key":"46","doi-asserted-by":"publisher","first-page":"7485","DOI":"10.1038\/srep07485","article-title":"Impacts of infection with different toxigenic Clostridium difficile strains on faecal microbiota in children","volume":"4","author":"Xiang","year":"2014","journal-title":"Sci Rep"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.23234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T10:57:49Z","timestamp":1589021869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.23234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,14]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,1,9]]}},"alternative-id":["23234","29423048"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.23234","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,14]]}}}