{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:26:50Z","timestamp":1768454810828,"version":"3.49.0"},"reference-count":35,"publisher":"Impact Journals, LLC","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2018,2,13]]},"DOI":"10.18632\/oncotarget.23853","type":"journal-article","created":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T10:36:03Z","timestamp":1514975763000},"page":"10445-10456","source":"Crossref","is-referenced-by-count":28,"title":["Selenium-binding protein 1 is down-regulated in malignant melanoma"],"prefix":"10.18632","volume":"9","author":[{"given":"Mandy","family":"Schott","sequence":"first","affiliation":[{"name":"University of Erlangen, Institute of Biochemistry, Biochemistry and Molecular Medicine, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam M.","family":"de Jel","sequence":"additional","affiliation":[{"name":"University of Erlangen, Institute of Biochemistry, Biochemistry and Molecular Medicine, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia C.","family":"Engelmann","sequence":"additional","affiliation":[{"name":"University of Regensburg, Institute of Functional Genomics, Statistical Bioinformatics, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Renner","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward K.","family":"Geissler","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja K.","family":"Bosserhoff","sequence":"additional","affiliation":[{"name":"University of Erlangen, Institute of Biochemistry, Biochemistry and Molecular Medicine, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke","family":"Kuphal","sequence":"additional","affiliation":[{"name":"University of Erlangen, Institute of Biochemistry, Biochemistry and Molecular Medicine, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2018,1,2]]},"reference":[{"key":"1","first-page":"335","article-title":"[Changes in the Incidence of Skin and Lip Cancer Between 1978 and 2007.] [Article in Spanish]","volume":"108","author":"Buend\u00eda-Eisman","year":"2017","journal-title":"Actas Dermosifiliogr"},{"key":"2","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/ng1148","article-title":"Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia","volume":"34","author":"Yudt","year":"2003","journal-title":"Nat Genet"},{"key":"3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.exer.2014.07.009","article-title":"Tg(Grm1) transgenic mice: a murine model that mimics spontaneous uveal melanoma in humans?","volume":"127","author":"Bosserhoff","year":"2014","journal-title":"Exp Eye Res"},{"key":"4","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1158\/0008-5472.CAN-06-3665","article-title":"Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma","volume":"67","author":"Chen","year":"2007","journal-title":"Cancer Res"},{"key":"5","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.bbagrm.2012.06.005","article-title":"Regulation of mGluR1 expression in human melanocytes and melanoma cells","volume":"1819","author":"Chen","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"6","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/pcmr.12244","article-title":"Transcriptome sequencing of melanocytic nevi and melanomas from Grm1 transgenic mice to determine melanoma driver mutations","volume":"27","author":"Bosserhoff","year":"2014","journal-title":"Pigment Cell Melanoma Res"},{"key":"7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/jn\/136.5.1311","article-title":"Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression","volume":"136","author":"Davis","year":"2006","journal-title":"J Nutr"},{"key":"8","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s10552-007-9072-y","article-title":"Vitamin E and selenium supplementation and risk of prostate cancer in the Vitamins and lifestyle (VITAL) study cohort","volume":"19","author":"White","year":"2008","journal-title":"Cancer Causes Control"},{"key":"9","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1002\/mnfr.200800103","article-title":"Selenium and the prevention of prostate and colorectal cancer","volume":"52","author":"Takata","year":"2008","journal-title":"Mol Nutr Food Res"},{"key":"10","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1097\/01.ju.0000107837.66277.e9","article-title":"Selenium: epidemiology and basic science","volume":"171","author":"Klein","year":"2004","journal-title":"J Urol"},{"key":"11","doi-asserted-by":"crossref","first-page":"e0127295","DOI":"10.1371\/journal.pone.0127295","article-title":"Evidence that selenium binding protein 1 is a tumor suppressor in prostate cancer","volume":"10","author":"Diamond","year":"2015","journal-title":"PLoS One"},{"key":"12","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/path.1524","article-title":"Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas","volume":"202","author":"Beer","year":"2004","journal-title":"J Pathol"},{"key":"13","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.3892\/ijo.2013.1850","article-title":"Selenium-binding protein 1 may decrease gastric cellular proliferation and migration","volume":"42","author":"Das","year":"2013","journal-title":"Int J Oncol"},{"key":"14","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1002\/ijc.21671","article-title":"Selenium binding protein 1 in ovarian cancer","volume":"118","author":"Ng","year":"2006","journal-title":"Int J Cancer"},{"key":"15","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1002\/mnfr.200700331","article-title":"Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer","volume":"52","author":"Augenlicht","year":"2008","journal-title":"Mol Nutr Food Res"},{"key":"16","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1158\/1078-0432.CCR-09-2801","article-title":"Decreased selenium-binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity","volume":"16","author":"Chang","year":"2010","journal-title":"Clin Cancer Res"},{"key":"17","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s12032-010-9482-7","article-title":"Reduced selenium-binding protein 1 is associated with poor survival rate in gastric carcinoma","volume":"28","author":"Lin","year":"2011","journal-title":"Med Oncol"},{"key":"18","doi-asserted-by":"crossref","first-page":"e63702","DOI":"10.1371\/journal.pone.0063702","article-title":"Reduced selenium-binding protein 1 in breast cancer correlates with poor survival and resistance to the anti-proliferative effects of selenium","volume":"8","author":"Yao","year":"2013","journal-title":"PLoS One"},{"key":"19","doi-asserted-by":"crossref","first-page":"e7774","DOI":"10.1371\/journal.pone.0007774","article-title":"Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts","volume":"4","author":"Yang","year":"2009","journal-title":"PLoS One"},{"key":"20","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1158\/1078-0432.CCR-12-0183","article-title":"Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1alpha to promote hepatocellular carcinoma invasiveness","volume":"18","author":"Fan","year":"2012","journal-title":"Clin Cancer Res"},{"key":"21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11010-005-5075-8","article-title":"Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells","volume":"277","author":"Rigaud","year":"2005","journal-title":"Mol Cell Biochem"},{"key":"22","doi-asserted-by":"crossref","first-page":"22528","DOI":"10.1074\/jbc.273.35.22528","article-title":"Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide","volume":"273","author":"Kola","year":"1998","journal-title":"J Biol Chem"},{"key":"23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1146\/annurev.nutr.27.061406.093716","article-title":"Metabolic regulation and function of glutathione peroxidase-1","volume":"27","author":"McClung","year":"2007","journal-title":"Annu Rev Nutr"},{"key":"24","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1093\/carcin\/bgq114","article-title":"Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein","volume":"31","author":"Yang","year":"2010","journal-title":"Carcinogenesis"},{"key":"25","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.3892\/or.2014.3141","article-title":"Selenium-binding protein 1 is associated with the degree of colorectal cancer differentiation and is regulated by histone modification","volume":"31","author":"Jiang","year":"2014","journal-title":"Oncol Rep"},{"key":"26","doi-asserted-by":"crossref","first-page":"D945","DOI":"10.1093\/nar\/gkq929","article-title":"COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer","volume":"39","author":"Stratton","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"27","doi-asserted-by":"crossref","first-page":"D652","DOI":"10.1093\/nar\/gkp995","article-title":"COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer","volume":"38","author":"Futreal","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"28","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.ejca.2010.01.031","article-title":"Constitutive HIF-1 activity in malignant melanoma","volume":"46","author":"Bosserhoff","year":"2010","journal-title":"Eur J Cancer"},{"key":"29","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.freeradbiomed.2014.11.015","article-title":"Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: a novel mechanism of cancer-specific cytotoxicity of selenite","volume":"79","author":"Xiong","year":"2015","journal-title":"Free Radic Biol Med"},{"key":"30","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1158\/0008-5472.CAN-08-3643","article-title":"Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition","volume":"69","author":"Arbeit","year":"2009","journal-title":"Cancer Res"},{"key":"31","first-page":"3927","article-title":"The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase","volume":"60","author":"Oberley","year":"2000","journal-title":"Cancer Res"},{"key":"32","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1158\/1535-7163.MCT-09-0924","article-title":"Telomerase as an important target of androgen signaling blockade for prostate cancer treatment","volume":"9","author":"Dong","year":"2010","journal-title":"Mol Cancer Ther"},{"key":"33","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1038\/nprot.2006.339","article-title":"Clonogenic assay of cells in vitro","volume":"1","author":"van Bree","year":"2006","journal-title":"Nat Protoc"},{"key":"34","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"feature Counts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Shi","year":"2014","journal-title":"Bioinformatics"},{"key":"35","first-page":"227","article-title":"Low-dose cancer risk modeling must recognize up-regulation of protection","volume":"8","author":"Neumann","year":"2009","journal-title":"Dose Response"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.23853","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T11:45:24Z","timestamp":1589024724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.23853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,2]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,2,13]]}},"alternative-id":["23853","29535818"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.23853","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,2]]}}}