{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T15:59:32Z","timestamp":1776700772499,"version":"3.51.2"},"reference-count":87,"publisher":"Impact Journals, LLC","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncotarget"],"published-print":{"date-parts":[[2018,2,20]]},"DOI":"10.18632\/oncotarget.24405","type":"journal-article","created":{"date-parts":[[2018,2,5]],"date-time":"2018-02-05T12:13:18Z","timestamp":1517832798000},"page":"11858-11875","source":"Crossref","is-referenced-by-count":69,"title":["Effects of the polyunsaturated fatty acids, EPA and DHA, on hematological malignancies: a systematic review"],"prefix":"10.18632","volume":"9","author":[{"given":"Milad","family":"Moloudizargari","sequence":"first","affiliation":[{"name":"Department of Immunology, School of Medicine, Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esmaeil","family":"Mortaz","sequence":"additional","affiliation":[{"name":"Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran"},{"name":"Clinical Tuberculosis and Epidemiology Research Center, National Research Institute for Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran"},{"name":"Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Hossein","family":"Asghari","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian M.","family":"Adcock","sequence":"additional","affiliation":[{"name":"Cell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, Dovehouse Street, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank A.","family":"Redegeld","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Garssen","sequence":"additional","affiliation":[{"name":"Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands"},{"name":"Nutricia Research Centre for Specialized Nutrition, Utrecht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7892","published-online":{"date-parts":[[2018,2,5]]},"reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"592S","DOI":"10.3945\/jn.111.155259","article-title":"Mechanisms of action of (n-3) fatty acids","volume":"142","author":"Calder","year":"2012","journal-title":"The Journal of nutrition"},{"key":"2","volume-title":"The Report of the British Nutrition Foundation\u2019s Task Force","author":"Acids","year":"1992"},{"key":"3","doi-asserted-by":"crossref","unstructured":"Geleijnse, Giltay, Grobbee, Donders, Kok. Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials. LWW. 2002.","DOI":"10.1097\/00004872-200208000-00010"},{"key":"4","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/MCO.0b013e3282f44bdf","article-title":"Omega-3 fatty acids: antiarrhythmic, proarrhythmic or both? current opinion in","volume":"11","author":"von Schacky","year":"2008","journal-title":"Clinical Nutrition & Metabolic Care"},{"key":"5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0005-2736(72)90116-2","article-title":"The properties of polyunsaturated lecithins in monolayers and liposomes and the interactions of these lecithins with cholesterol","volume":"266","author":"van Deenen","year":"1972","journal-title":"Biochimica et Biophysica Acta (BBA)-Biomembranes"},{"key":"6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s11745-000-0495-0","article-title":"Dietary docosahexaenoic acid suppresses inflammation and immunoresponses in contact hypersensitivity reaction in mice","volume":"35","author":"Tanaka","year":"2000","journal-title":"Lipids"},{"key":"7","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0167-4889(01)00143-4","article-title":"Prevention of docosahexaenoic acid-induced cytotoxicity by phosphatidic acid in jurkat leukemic cells: the role of protein phosphatase-1","volume":"1541","author":"Stillwell","year":"2001","journal-title":"Biochimica et Biophysica Acta - Molecular Cell Research"},{"key":"8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.urolonc.2005.03.001","article-title":"An introduction to dietary\/supplemental omega-3 fatty acids for general health and prevention: Part II","volume":"23","author":"Moyad","year":"2005","journal-title":"Urologic Oncology: Seminars and Original Investigations"},{"key":"9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s11745-008-3263-5","article-title":"The antiproliferative effect of EPA in HL60 cells is mediated by alterations in calcium homeostasis","volume":"44","author":"Schonberg","year":"2009","journal-title":"Lipids"},{"key":"10","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.3390\/ijms17081257","article-title":"Docosahexaenoic acid induces oxidative DNA damage and apoptosis, and enhances the chemosensitivity of cancer cells","volume":"17","author":"Kim","year":"2016","journal-title":"International Journal of Molecular Sciences"},{"key":"11","first-page":"119","article-title":"effects of omega-3 fatty acids on regulatory t cells in hematologic neoplasms","volume":"35","author":"Trindade","year":"2013","journal-title":"Revista Brasileira de Hematologia e Hemoterapia"},{"key":"12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.lfs.2017.07.020","article-title":"Melatonin as a multifunctional anti-cancer molecule: Implications in gastric cancer","volume":"185","author":"Abdollahi","year":"2017","journal-title":"Life Sciences"},{"key":"13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/ijc.20462","article-title":"Enhancement of arsenic trioxide-mediated apoptosis using docosahexaenoic acid in arsenic trioxide-resistant solid tumor cells","volume":"112","author":"Bachleitner-Hofmann","year":"2004","journal-title":"International Journal of Cancer"},{"key":"14","doi-asserted-by":"crossref","first-page":"4990","DOI":"10.1182\/blood-2002-08-2391","article-title":"Docosahexaenoic acid enhances arsenic trioxide-mediated apoptosis in arsenic trioxide-resistant HL-60 cells","volume":"101","author":"Bachleitner-Hofmann","year":"2003","journal-title":"Blood"},{"key":"15","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1093\/jn\/133.6.1913","article-title":"Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts","volume":"133","author":"Chapkin","year":"2003","journal-title":"The Journal of nutrition"},{"key":"16","doi-asserted-by":"crossref","first-page":"37335","DOI":"10.1074\/jbc.M106193200","article-title":"Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition","volume":"276","author":"Waldhausl","year":"2001","journal-title":"Journal of Biological Chemistry"},{"key":"17","first-page":"821","article-title":"Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids","volume":"62","author":"Utsumi","year":"2001","journal-title":"Biochemical Pharmacology"},{"key":"18","first-page":"9","article-title":"Eicosapentaenoic acid activates RAS\/ERK\/C\/EBP\u03b2 pathway through H-ras intron 1 CpG island demethylation in U937 leukemia cells","author":"Vecchini","year":"2014","journal-title":"PLoS ONE"},{"key":"19","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/biof.181","article-title":"Docosahexaenoic acid: a natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects","volume":"37","author":"Altenburg","year":"2011","journal-title":"BioFactors"},{"key":"20","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.jnutbio.2014.06.013","article-title":"Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells","volume":"25","author":"Redegeld","year":"2014","journal-title":"Journal of Nutritional Biochemistry"},{"key":"21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ejphar.2016.10.038","article-title":"Novel n-3 PUFA monoacylglycerides of pharmacological and medicinal interest: anti-inflammatory and anti-proliferative effects","volume":"792","author":"Rousseau","year":"2016","journal-title":"European Journal of Pharmacology"},{"key":"22","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0271-5317(00)00285-2","article-title":"Regulation of cellular differentiation and apoptosis by fatty acids and their metabolites","volume":"21","author":"Erickson","year":"2001","journal-title":"Nutrition Research"},{"key":"23","first-page":"257","article-title":"Evaluation of the anti-proliferative activity of natural lipid preparations against tumor cell lines","volume":"13","author":"Usydus","year":"2014","journal-title":"Journal of East Asian Studies"},{"key":"24","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1182\/blood-2006-04-015537","article-title":"Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1","volume":"109","author":"Nicot","year":"2007","journal-title":"Blood"},{"key":"25","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.plefa.2013.01.004","article-title":"Arachidonic acid enhances TPA-induced differentiation in human leukemia HL-60 cells via reactive oxygen species-dependent ERK activation","volume":"88","author":"Chen","year":"2013","journal-title":"Prostaglandins Leukotrienes and Essential Fatty Acids"},{"key":"26","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1042\/bj3360451","article-title":"Cell proliferation, apoptosis and accumulation of lipid droplets in U937-1 cells incubated with eicosapentaenoic acid","volume":"336","author":"Kolset","year":"1998","journal-title":"Biochemical Journal"},{"key":"27","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0952-3278(97)90572-X","article-title":"Cytotoxic action of alpha-linolenic and eicosapentaenoic acids on myeloma cells","volume":"56","author":"Das","year":"1997","journal-title":"Prostaglandins, leukotrienes, and essential fatty acids"},{"key":"28","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0022-4804(02)96496-6","article-title":"Eicosapentaenoic acid and \u03b3-linolenic acid induce apoptosis in HL-60 cells","volume":"107","author":"Karlstad","year":"2002","journal-title":"Journal of Surgical Research"},{"key":"29","first-page":"91","article-title":"Docosahexaenoic acid induces apoptosis in primary chronic lymphocytic leukemia cells","volume":"7","author":"Bay","year":"2015","journal-title":"Hematology Reports"},{"key":"30","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0005-2760(98)00015-0","article-title":"Distinctive inhibitory activity of docosahexaenoic acid against sphingosine-induced apoptosis","volume":"1391","author":"Masuzawa","year":"1998","journal-title":"Biochimica Et Biophysica Acta-Lipids and Lipid Metabolism"},{"key":"31","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s11745-002-0963-6","article-title":"Eicosapentaenoic acid promotes apoptosis in Ramos cells via activation of caspase-3 and -9","volume":"37","author":"Hollung","year":"2002","journal-title":"Lipids"},{"key":"32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/10715760500043587","article-title":"Involvement of hydroperoxide in mitochondria in the induction of apoptosis by the eicosapentaenoic acid","volume":"39","author":"Nakagawa","year":"2005","journal-title":"Free Radical Research"},{"key":"33","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1080\/10715760500264654","article-title":"Role of calcium-induced mitochondrial hydroperoxide in induction of apoptosis of RBL2H3 cells with eicosapentaenoic acid treatment","volume":"39","author":"Nakagawa","year":"2005","journal-title":"Free Radical Research"},{"key":"34","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1271\/bbb.68.2415","article-title":"Docosahexaenoic acid induces apoptosis via the bax-independent pathway in HL-60 cells","volume":"68","author":"Takahata","year":"2004","journal-title":"Bioscience, Biotechnology and Biochemistry"},{"key":"35","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11010-005-1090-z","article-title":"Docosahexaenoic acid-containing phosphatidylethanolamine enhances HL-60 cell differentiation by regulation of c-jun and c-myc expression","volume":"275","author":"Takahashi","year":"2005","journal-title":"Molecular and Cellular Biochemistry"},{"key":"36","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0304-3835(99)00224-4","article-title":"Induction of apoptosis in HL-60 cells by eicosapentaenoic acid (EPA) is associated with downregulation of bcl-2 expression","volume":"145","author":"Wan","year":"1999","journal-title":"Cancer Lett"},{"key":"37","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.arr.2017.09.005","article-title":"Autophagy, its mechanisms and regulation: implications in neurodegenerative diseases","volume":"40","author":"Abdollahi","year":"2017","journal-title":"Ageing Res Rev"},{"key":"38","first-page":"789","article-title":"Induction of apoptosis by dietary polyunsaturated fatty acids in human leukemic cells is not associated with DNA fragmentation","volume":"17","author":"Ooi","year":"2000","journal-title":"International journal of oncology"},{"key":"39","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1182\/blood.V84.11.3799.bloodjournal84113799","article-title":"Effect of n-3 and n-6 fatty acids on proliferation and differentiation of promyelocytic leukemic HL-60 cells","volume":"84","author":"Drevon","year":"1994","journal-title":"Blood"},{"key":"40","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/sj.leu.2401030","article-title":"Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids","volume":"12","author":"Drevon","year":"1998","journal-title":"Leukemia"},{"key":"41","first-page":"737","article-title":"Docosahexaenoic acid modulates different genes in cell cycle and apoptosis to control growth of human leukemia HL-60 cells","volume":"25","author":"Ooi","year":"2004","journal-title":"International journal of oncology"},{"key":"42","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0167-4889(00)00128-2","article-title":"Docosahexaenoic acid induces apoptosis in jurkat cells by a protein phosphatase-mediated process","volume":"1499","author":"Stillwell","year":"2001","journal-title":"Biochimica et Biophysica Acta - Molecular Cell Research"},{"key":"43","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/bj20021667","article-title":"Cell-cycle arrest in jurkat leukaemic cells: a possible role for docosahexaenoic acid","volume":"371","author":"Zaloga","year":"2003","journal-title":"Biochemical Journal"},{"key":"44","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1089\/jmf.2013.2935","article-title":"Eicosapentaenoic acid and docosahexaenoic acid suppress Th2 cytokine expression in RBL-2H3 basophilic leukemia cells","volume":"17","author":"Pyo","year":"2014","journal-title":"Journal of Medicinal Food"},{"key":"45","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.cell.2007.01.029","article-title":"The epigenomics of cancer","volume":"128","author":"Baylin","year":"2007","journal-title":"Cell"},{"key":"46","doi-asserted-by":"crossref","first-page":"27092","DOI":"10.1074\/jbc.M111.253609","article-title":"Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT\/enhancer-binding protein delta in U937 leukemia cells","volume":"286","author":"Vecchini","year":"2011","journal-title":"Journal of Biological Chemistry"},{"key":"47","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1124\/mol.107.039792","article-title":"Docosahexaenoic acid induces increases in Ca2+ (i) via inositol 1,4,5-triphosphate production and activates protein kinase C gamma and -delta via phosphatidylserine binding site: implication in apoptosis in U937 cells","volume":"72","author":"Khan","year":"2007","journal-title":"Molecular Pharmacology"},{"key":"48","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1038\/sj.bjp.0705563","article-title":"Docosahexaenoic acid and other fatty acids induce a decrease in pH i in jurkat t-cells","volume":"140","author":"Khan","year":"2003","journal-title":"British Journal of Pharmacology"},{"key":"49","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1006\/bbrc.1998.8810","article-title":"On the mechanism of action of econazole, the capacitative calcium inflow blocker","volume":"248","author":"Bygrave","year":"1998","journal-title":"Biochemical and biophysical research communications"},{"key":"50","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0167-4889(98)00159-1","article-title":"Multiple effects of econazole on calcium signaling: depletion of thapsigargin-sensitive calcium store, activation of extracellular calcium influx, and inhibition of capacitative calcium entry","volume":"1448","author":"Tseng","year":"1999","journal-title":"Biochimica et Biophysica Acta (BBA)-Molecular Cell Research"},{"key":"51","first-page":"175","article-title":"Dietary docosahexaenoic acid levels influence the outcome of arabinosylcytosine chemotherapy in L1210 leukemic mice","volume":"44","author":"Meckling","year":"2002","journal-title":"Nutrition and Cancer"},{"key":"52","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1158\/1940-6207.CAPR-15-0050","article-title":"Chemopreventive effects of dietary eicosapentaenoic acid supplementation in experimental myeloid leukemia","volume":"8","author":"Prabhu","year":"2015","journal-title":"Cancer Prevention Research"},{"key":"53","doi-asserted-by":"crossref","first-page":"E109","DOI":"10.1152\/ajpendo.1991.261.1.E109","article-title":"Differential effects of omega-3 fish oils on protein kinase activities","volume":"261","author":"Brunton","year":"1991","journal-title":"American Journal of Physiology-Endocrinology and Metabolism"},{"key":"54","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.3945\/jn.116.231639","article-title":"Membrane disordering by eicosapentaenoic acid in B lymphomas is reduced by elongation to docosapentaenoic acid as revealed with solid-state nuclear magnetic resonance spectroscopy of model membranes","volume":"146","author":"Shaikh","year":"2016","journal-title":"The Journal of nutrition"},{"key":"55","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1016\/0006-2952(93)90447-5","article-title":"Effects of polyunsaturated fatty acids on the efficacy of antineoplastic agents toward L5178Y lymphoma cells","volume":"45","author":"Black","year":"1993","journal-title":"Biochemical pharmacology"},{"key":"56","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s11745-001-0765-x","article-title":"Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants","volume":"36","author":"Drevon","year":"2001","journal-title":"Lipids"},{"key":"57","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s11745-002-0963-6","article-title":"Eicosapentaenoic acid promotes apoptosis in ramos cells via activation of caspase-3 and-9","volume":"37","author":"Hollung","year":"2002","journal-title":"Lipids"},{"key":"58","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s11745-003-1059-z","article-title":"Eicosapentaenoic acid-induced apoptosis depends on acyl CoA-synthetase","volume":"38","author":"Drevon","year":"2003","journal-title":"Lipids"},{"key":"59","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1002\/(SICI)1097-0142(20000415)88:8<1916::AID-CNCR22>3.0.CO;2-F","article-title":"Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma","volume":"88","author":"Hand","year":"2000","journal-title":"Cancer"},{"key":"60","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1016\/0899-9007(95)00066-6","article-title":"Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia","volume":"12","author":"Tisdale","year":"1996","journal-title":"Nutrition"},{"key":"61","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0952-3278(03)00007-3","article-title":"The effects on plasma, red cell and platelet fatty acids of taking 12g\/day of ethyl-eicosapentaenoate for 16 months: dihomogammalinolenic, arachidonic and docosahexaenoic acids and relevance to Inuit metabolism","volume":"68","author":"Muskiet","year":"2003","journal-title":"Prostaglandins, leukotrienes and essential fatty acids"},{"key":"62","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0306-9877(03)00075-6","article-title":"A low toxicity maintenance regime, using eicosapentaenoic acid and readily available drugs, for mantle cell lymphoma and other malignancies with excess cyclin D1 levels","volume":"60","author":"Horrobin","year":"2003","journal-title":"Medical hypotheses"},{"key":"63","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00277-010-0904-6","article-title":"Abnormal fatty acid distribution of the serum phospholipids of patients with non-Hodgkin lymphoma","volume":"89","author":"Glibeti\u0107","year":"2010","journal-title":"Annals of hematology"},{"key":"64","first-page":"3905","article-title":"Polyunsaturated fatty acids induce cell death in YAC-1 lymphoma by a caspase-3-independent mechanism","volume":"23","author":"Alvarez de Cienfuegos","year":"2002","journal-title":"Anticancer research"},{"key":"65","first-page":"1678","article-title":"Docosahexaenoic acid enhances the toxic effect of imatinib on Bcr-Abl expressing HL-60 cells","volume":"21","author":"Curi","year":"2007","journal-title":"Toxicology"},{"key":"66","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1158\/1535-7163.MCT-06-0608","article-title":"Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity","volume":"6","author":"Lind","year":"2007","journal-title":"Molecular Cancer Therapeutics"},{"key":"67","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s12032-013-0741-2","article-title":"Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin\u2019s lymphoma patients","volume":"30","author":"Glibeti\u0107","year":"2013","journal-title":"Medical Oncology"},{"key":"68","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1158\/1535-7163.MCT-06-0067","article-title":"Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells","volume":"5","author":"Lind","year":"2006","journal-title":"Molecular Cancer Therapeutics"},{"key":"69","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0024-3205(00)00714-1","article-title":"Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388\/DOX resistant and P388 parental cell lines","volume":"67","author":"Tan","year":"2000","journal-title":"Life Sciences"},{"key":"70","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.phrs.2005.02.024","article-title":"Differential effects of eicosapentaenoic and docosahexaenoic acids upon oxidant-stimulated release and uptake of arachidonic acid in human lymphoma U937 cells","volume":"52","author":"Ross","year":"2005","journal-title":"Pharmacological research"},{"key":"71","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0022-2275(20)32403-2","article-title":"Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis","volume":"41","author":"Drevon","year":"2000","journal-title":"Journal of Lipid Research"},{"key":"72","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0005-2736(98)00039-X","article-title":"Docosahexaenoic acid (DHA) alters the structure and composition of membranous vesicles exfoliated from the surface of a murine leukemia cell line","volume":"1371","author":"Stillwell","year":"1998","journal-title":"Biochimica et Biophysica Acta - Biomembranes"},{"key":"73","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.plefa.2009.05.004","article-title":"Toxicology and safety of DHA","volume":"81","author":"Lien","year":"2009","journal-title":"Prostaglandins, leukotrienes and essential fatty acids"},{"key":"74","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.plefa.2014.07.012","article-title":"A new, microalgal DHA-and EPA-containing oil lowers triacylglycerols in adults with mild-to-moderate hypertriglyceridemia","volume":"91","author":"Geohas","year":"2014","journal-title":"Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)"},{"key":"75","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/pbc.21852","article-title":"The use of a protein and energy dense eicosapentaenoic acid containing supplement for malignancy-related weight loss in children","volume":"52","author":"Tanyeli","year":"2009","journal-title":"Pediatric Blood and Cancer"},{"key":"76","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1080\/01635580802582777","article-title":"Antineoplastic Effects of N-3 Polyunsaturated fatty acids in combination with drugs and radiotherapy: preventive and therapeutic strategies","volume":"61","author":"Pessina","year":"2009","journal-title":"Nutrition and Cancer-an International Journal"},{"key":"77","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1017\/S000711450765795X","article-title":"n-3 Fatty acids, cancer and cachexia: a systematic review of the literature","volume":"97","author":"Casimiro","year":"2007","journal-title":"British Journal of Nutrition"},{"key":"78","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/cncr.20362","article-title":"Phase II study of high-dose fish oil capsules for patients with cancer-related cachexia","volume":"101","author":"Paskett","year":"2004","journal-title":"Cancer"},{"key":"79","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1136\/gut.52.10.1479","article-title":"Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial","volume":"52","author":"Tisdale","year":"2003","journal-title":"Gut"},{"key":"80","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.plefa.2006.11.001","article-title":"Antioxidant modulation of oxidant-stimulated uptake and release of arachidonic acid in eicosapentaenoic acid-supplemented human lymphoma U937 cells","volume":"76","author":"Ross","year":"2007","journal-title":"Prostaglandins, leukotrienes and essential fatty acids"},{"key":"81","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.yrtph.2010.09.007","article-title":"Safety assessment of EPA-rich triglyceride oil produced from yeast: genotoxicity and 28-day oral toxicity in rats","volume":"59","author":"Gillies","year":"2011","journal-title":"Regulatory Toxicology and Pharmacology"},{"key":"82","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1182\/blood-2012-01-403105","article-title":"Dietary eicosapentaenoic acid (EPA) to produce antileukemic cyclopentenone prostaglandin J3?","volume":"119","author":"Stichtenoth","year":"2012","journal-title":"Blood"},{"key":"83","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/jhn.12471","article-title":"Oral fish oil positively influences nutritional-inflammatory risk in patients with haematological malignancies during chemotherapy with an impact on long-term survival: a randomised clinical trial","volume":"30","author":"Nunes","year":"2017","journal-title":"Journal of Human Nutrition and Dietetics"},{"key":"84","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/BF01920754","article-title":"Antiproliferative effect of polyunsaturated fatty acids and interleukin-2 on normal and abnormal human lymphocytes","volume":"50","author":"Das","year":"1994","journal-title":"Experientia"},{"key":"85","first-page":"12","article-title":"Omega 3 fatty acids increase the chemo-sensitivity of B-CLL-derived cell lines EHEB and MEC-2 and of B-PLL-derived cell line JVM-2 to anti-cancer drugs doxorubicin, vincristine and fludarabine","author":"Hardman","year":"2013","journal-title":"Lipids in Health and Disease"},{"key":"86","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF02535772","article-title":"Docosahexaenoic acid increases permeability of lipid vesicles and tumor cells","volume":"28","author":"Jenski","year":"1993","journal-title":"Lipids"},{"key":"87","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.bcp.2005.05.008","article-title":"Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation","volume":"70","author":"Mizushina","year":"2005","journal-title":"Biochemical Pharmacology"}],"container-title":["Oncotarget"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.24405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T22:40:09Z","timestamp":1660430409000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.oncotarget.com\/lookup\/doi\/10.18632\/oncotarget.24405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,5]]},"references-count":87,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2018,2,20]]}},"alternative-id":["24405","29545942"],"URL":"https:\/\/doi.org\/10.18632\/oncotarget.24405","relation":{},"ISSN":["1949-2553"],"issn-type":[{"value":"1949-2553","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,5]]}}}